Laboratory Safety Design by u9GScg

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									        Safe Laboratory Design

American Chemical
Society
Charlotte, NC
March 24, 2004
           Safe Laboratory Design

 Purpose
     Eliminate or minimize employee exposure to
      hazardous materials used in laboratories. Human
      comfort and safety.
 Method
     Use of good design and engineering techniques
         Safe Laboratory Design

Components


    Establish   a guidance document
    Must  have good architectural and
    engineering firm with relevant
    experience
    Cooperative   work with
    institutional safety office
           Safe Laboratory Design

 Institutional Guidance Document
     Institutional Policy
     Design Specifics
         Safe Laboratory Design


 Assess user needs
 Design within
  regulatory framework
 Work within current
  institutional
  infrastructure
                       User Needs

 Laboratory Planning
 Material needs
      Type of case work
      Fume hood construction
          Polymer
          Stainless
          Composite
 Placement of biological safety cabinets and
  chemical fume hoods
                       User Needs

Chemical
       Type of work
       Type of chemicals
Biomedical
       Infectious agents
        Level 2-3
Radioactive
       Isotope used
       Activity
          Hazardous Materials

 Physical and Health Hazards
             Hazardous Materials

   Flammable liquid
   Oxidizers
   Pyrophoric
   Water Reactive
   Toxic
   Infectious
   Radioactive
   Select Agent
Hazardous Chemicals
           Routes of Exposure

 Inhalation
 Ingestion
 Dermal
                Routes of Exposure

 Inhalation
      Efficient way to
       introduce chemicals
       into the body
               Routes of Exposure

 Ingestion
      Dust
      Contaminated
       Consumables
      Other
                 Routes of Exposure

 Dermal
     Lipophyllic Compounds
         DMSO
              Chemical Storage

 Nature of hazard
     Flammable solvents
     NFPA 30
x
 Separation by compatibility
      Code and Regulatory Issues

 Regulatory agencies prefer that hazards be
  controlled by engineering methods.
            Regulatory Agencies

 Federal
 State
 Local
               Regulatory Agencies

 Federal
     Occupational Safety and Health Administration
       Occupational Exposure to Hazardous Chemicals in
        Laboratories
       Blood Borne Pathogen Standard

     Environmental Protection Agency
         Hazardous Waste
     Nuclear Regulatory Agency
         Radioisotope Use
             Regulatory Agencies

 State
     Environmental Protection Division
     OSHA
     Radiation Protection
     Building Codes
                    Regulatory

 Local
     National Fire Protection Association (NFPA)
       NFPA 5000
       NFPA 45

       NFPA 30

     Building Codes
              Engineering Methods

 Laboratory design to
  control hazards
      Ventilation
      Safety Devices
      Storage
          Laboratory Ventilation

 Directional air flow
  (negative to corridor)
 No re-circulated air
  (single pass)
 10-12 Air changes per
  hour (more in
  vivarium)
 Point source
  containment
             Chemical Fume Hoods

 Point source control
      Average flow rate of
       100 linear feet per
       minute at a set sash
       height
      VAV hoods
Fume Hood Controls
           Point Source Control

 Gas cabinets
 Glove box
               Ventilation Control

 Fans
     Terminal end of duct
 Controls
     DDC controls
     VAV fume hoods
            Fume Hood Exhaust

 Design to prevent re-
  entrainment.
                  Safety Devices

   Restraints
   Pressure Relief
   Shielding
   Instruments
                   Restraints

 Compressed gas
                      Shielding

 Explosions
     Pressure Relief
     NFPA 58
     Specifically engineered
 Radiation
     Shielding
                        Instruments

 Instruments to warn
      Oxygen levels
      Fluorine gas level
            Hazardous Waste

 Need facilities for handling surplus
  hazardous materials and hazardous waste.
 EPA
 DOT
       Hazardous Waste Facilities

 Manipulation and
  storage of large
  quantities of hazardous
  materials.
       Hazardous Waste Facilities

 Able to contain
  potential release of
  highly regulated
  chemicals.
       Hazardous Waste Facilities

 Appropriate services
Hazardous Waste Facilities
             Safety Equipment

 Explosion Proof
  Freezers
Hazardous Waste
                   Summary

 Design to fit specific needs of the laboratory
  functions
 Design within regulatory framework
 Work with the institutional safety office

								
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