HIV / AIDS
THE EFFECTS OF HIGHLY ACTIVE
FORMULAE IN THE TREATMENT OF
HIV / AIDS
IDIOPATHIC CD-4 LYMPHOCYTOPENIA
( ICL )
Prof. Dr. Ananthan Krishnan PhD.
Geethanjali Gausillia Kathirvalu
Alternative Medicine Research Institute
Center for Asia
Acquired immune deficiency syndrome or acquired immunodeficiency
syndrome (AIDS or Aids) is a set of symptoms and infections resulting from
the damage to the human immune system caused by the human
immunodeficiency virus (HIV). This condition progressively reduces the
effectiveness of the immune system and leaves individuals susceptible to
opportunistic infections and tumors. This study was aimed to assess the
affects of highly active micro-nutrient wholesome formulae which are made
out of Seeds, Beans, Cereals and Vitamins (SBCVs). It is a non-invasive
alternative treatment in treating HIV/AIDS. Total nutritional formulas can
constantly optimize the body’s physiological and bio-chemical balance
which can be reducing gradually. The viral replication and with time
eliminate the virus from the system. This treatment has proven to be
effective as the CD4+ count of the patients studied was significantly raised,
without using any allopathic anti-retroviral drugs. Patients also had a very
good increase in weight, stamina and strength. They were also getting
themselves into their normal life that they used to have before contracting
the disease. The level of CD4 count of patients who were studied also
increased. The study proved that CD4 count is not the absolute parameter
for the indication of the status and HIV/AIDS of a person. Other mechanism
of immunological defense has developed with the aid of Mas Ayu product.
Through the verbal assessment carried out among the patient. It showed that
patients were overwhelmed and stated that the treatment is commendable
and helped them to regain their health. Conclusively, the study revealed that
the natural product made of highly active micro-nutrient wholesome
formulae is effective against HIV and it should be made available to treat
HIV and AIDS patients. SBCV package is the natural answer for both
prevention and treatment and even cure.
LIST OF TABLES iii
LIST OF FIGURES iv
LIST OF ABBREVIATIONS v
CHAPTER 1: INTRODUCTION
1.1 Introduction to HIV 1
1.2 Aim and Objective of the Study 4
CHAPTER II: LITERATURE REVIEW
2.1 General information about HIV 5
2.2 AIDS without HIV 6
2.3 World statistic on HIV cases 8
2.4 Routes of transmission 9
2.5 Incubation period 10
2.6 Diagnosis 10
2.7 Phylosophy and concept of Natural Healthcare 11
2.8 Comparative treatment 14
2.8.1 Allopathic treatment 15
2.8.2 Study detail 18
2.8.3 Side effects of HARRT 19
2.8.4 Cost 21
2.8.5 Effectiveness 22
2.9 Naturopathic treatment 23
2.9.1 Product used 26
2.9.2 Side effects of Natural Product 28
2.9.3 Cost 28
2.9.4 Effectiveness of HAMNWF 29
2.10 Comparative analysis of the two treatment 29
2.11 Prevention of HIV 30
2.12 Care for HIV/AIDS patients 34
CHAPTER III: METHODOLOGY
3.1 Study location 36
3.2 Sample 36
3.3 Methodology of the study 37
3.4 Case Studies 38
CHAPTER IV: CONCLUSION
4.1 General conclusion 57
APPENDIX I 60
APPENDIX B 61
LIST OF TABLES
Numbers of Tables Page
Table 2.1 Comparative analyses of allopathic and naturopathic 18
Table 3.1 Viral load and CD4 count 42
Table 3.2 Natural nutritional treatment 45
Table 3.3 Lab test result 45
Table 3.4 Natural nutritional treatment 47
Table 3.5 Lab test report 48
Table 3.6 Progress of patient CD4+ 54
Table 3.7 Natural nutritional treatment 56
LIST OF FIGURES
Numbers of figures Page
Figure 1.1 Model of Human Immunodeficiency Virus 1
Figure 2.1 Products used 26
Figure 3.1 Madam Parameswary 38
Figure 3.2 Madam Parameswary with Prof.AK 39
Figure 3.3 Mr. Doraisamy 41
Figure 3.4 En. Abdullah bin Abdul Ghani 44
Figure 3.5 En. Jaafar bin Daud 46
Figure 3.6 En. Yusri 49
Figure 3.7 Mr. Benjamin Ong 51
Figure 3.7 Mr. Benjamin Ong 52
Figure 4.8 CD4+ Count of Zainudin 54
LIST OF ABBREVIATION
< Less than
> More than
= Equal to
HIV Human Immunodeficiency Virus
AIDS Acquired Immune Deficiency Syndrome
RNA Ribonucleic Acid
DNA Deoxyribonucleic Acid
IgG Immunoglobulin G
IgM Immunoglobulin M
GH General Hospital
USD United States Dollars
SBCV Seed, Bean, Cereal and Vitamin
HAMNWF Highly Active Micro Nutrient Wholesome Formulae
ELISA Enzyme Linked Immunosorbent Assay
1.1 INTRODUCTION TO HIV
HIV (Human Immunodeficiency Virus) is a retrovirus1 that infects and ultimately depletes
the CD4+ population of helper T lymphocyte2 cells in the body. As levels of these cells
fall, the patient moves into the phase of having AIDS (Acquired Immune Deficiency
Syndrome). This is an incurable disease where the cells are in a profound state of
immunodeficiency. The inability to fight disease at a cellular level puts the patient at a high
risk of developing opportunistic infections. This disease is defined as a CD4+ count of less
than 200uL (this is when the CD4+ cells account for less than 14% of the lymphocyte
population of an HIV+ person).
Figure 1: Model of Human Immunodeficiency Virus
Retrovirus …A retrovirus is any virus belonging to the viral family Retroviridae. They are enveloped
viruses possessing an RNA genome, and replicate via a DNA intermediate.
T lymphocyte…belong to a group of white blood cells known as lymphocytes, and play a central role in
After being introduced into the body the virus replicates freely in the blood. Viremia3 peaks
two to three weeks after infection, reaching very high levels. With primary HIV infection,
there are usually no clinical signs. 50 to 70% of patients show signs of acute retroviral
syndrome, which starts two to four weeks after exposure. This can last up to six weeks. It is
characterized by a febrile illness with an abrupt onset. It resembles mononucleosis and lasts
for a period of one to two weeks. The signs and symptoms include pharyngitis4, rash,
thrush, diarrhea, nausea, vomiting, and lymphadenopathy5, mucocutaneous6 ulcerations of
the mouth, esophagus and the genitals.
Patients with the acute retroviral syndrome can remain asymptomatic for the next few
years. The peripheral blood mononuclear cells carry a relatively small amount of the virus.
HIV is found in higher concentration in the lymphoid tissue. As a result most patients
develop persistent generalized lymphadenopathy. In this case, the best measure of the
immunological depression is the CD4+ count.
HIV not only affects the CD4+ lymphocytes, but also affects the monocytes and
macrophages. The virus does not kill them. The infected macrophages carry the virus to the
tissues and organs. HIV interferes with the cytokine production which further hampers
cellular immunity levels. HIV infected persons produce too little gamma interferon, which
activates the macrophages to kill intracellular pathogens and too little interleukin-2 which
is responsible for the proliferation of T cells. The virus basically does not give the body
what it needs in order to defend itself against infections – it stops the growth of the
“fighter” T cells and does not allow the “eating” macrophage cells to become activated.
Viremia is a medical condition where viruses enter the bloodstream and hence have access to the rest
of the body.
Pharyngitis is an inflammation of the pharynx. It frequently results in a sore throat.
Lymphadenopathy is a term meaning "disease of the lymph nodes." It is, however,
almost synonymously used with "swollen/enlarged lymph nodes".
Monocyte is a leukocyte, part of the human body's immune system that protects against blood-borne
pathogens and moves quickly to sites of infection in the tissues.
During the first few years of infection, the CD4+ count falls by an average of only 30 cells
uL/yr. This again, is subject to individual variation. After five to eight years of infection,
the rate of depletion rises to 50 to 100 cells uL/yr. This predicts the shift from HIV to AIDS
within 18 to 24 months.
When CD4+ counts are over 500uL, the only clinical manifestation may be an unusual
susceptibility to virulent pathogens such as Streptococus Pneumoniae7. When the CD4+
counts drop below 500uL, patients tend to develop pneumonococcal or other bacterial
pneumonia, reactivation of varicella zoster virus (shingles) and tuberculosis. After seven to
eight years of infection, most patients with CD4+ counts over 200 to 300 uL are still
asymptomatic but show increased cytokine expression, acid-labile interferon, beta2-
microglobulin and interleukin-2 receptors. Patients may now start to experience weight
loss, fever, night sweats, thrombocytopenia and other infections. When the CD4+ count
falls lower than 200uL, the risk for greatly progressive diseases is higher. These diseases
include pneumonia, herpes, and tuberculosis and mycobacterial8 infections.
The cytotoxic T lymphocytes which appear after the first two to three weeks are the body's
first response to HIV. These T cells bring a three to five log decrease in HIV concentrations
in peripheral blood. There is a sudden decline of the virus in the body, which suggests that
the host immune system suppresses HIV partially in the initial stages of the infection. 6 to
twelve weeks after infection, the body begins producing IgG, IgA and IgM antibodies
against the HIV antigen present in the serum. The presence of these antibodies in the
patient’s serum is what forms the basis of an HIV test.
Streptococus Pneumoniae is a significant human pathogen, S. pneumoniae was recognized as a major
cause of pneumonia
Mycobacterial is the pathogens known to cause serious diseases in mammals, including tuberculosis and
1.2 Aims and Objective of the Study
The primary aim of this preliminary outcome driven natural medicine therapy study is to
assess the clinical value of safe SBCV9 which are highly active micro-nutrient wholesome
natural formulae in the non - invasive treatment of confirmed HIV/AIDS cases that were
referred to AK Pharmacy and Naturopathy Center by the kith and kin of patients either
admitted to the hospitals or who were detected in the private clinics.
SBCV- Seed, Bean, Cereal and Vitamins
2.1 GENERAL INFORMATION ABOUT HIV
AIDS – THE CONVENTIONAL THEORY
The conventional theory subscribes to the scientific belief that HIV or Human Immuno-
Deficiency Virus is the sole primary cause of AIDS. The entire hypothesis of the theory is
based exclusively on the claims by Luc Montagnier and Robert Gallo, M.D. of the National
Cancer Institute, who in April of 1984 announced that AIDS was a retrovirus with tumor
In an earlier 1983 paper published in Science, Montagnier and his colleagues presented
three lines of evidence which they claimed proved the existence of a new human
exogenous immunodeficiency virus, presently known as human immunodeficiency virus or
HIV. These were detection of (i) reverse transcriptase activity (ii) retrovirus-like particles
(iii) immunological reactivity between proteins from the culture supernatant banded at the
density of 1.16g/ml (purified virus) and antibodies in a patient’s (BRU) serum.
The purpose of a hypothesis is to explain observations and make predictions. The HIV
hypothesis proposed was 3-fold (1) high frequency of malignant Kaposi’s sarcoma, (2)
opportunistic infections and (3) a decrease in T4 lymphocytes. The hypothesis proposed
that HIV kills the T4 cells and the decrease of T4 cells leads to the appearance of diseases
and symptoms which constitute the clinical syndrome.
The theory predicted that HIV was sexually transmitted and AIDS would spread
indiscriminately throughout the heterosexual population causing an AIDS epidemic
‘unparalleled in recorded history’ placing persistent IV drug users, homosexuals and
prostitutes (through blood and body fluid) in the high risk group.
This theory compounded by the broad spectrum of opportunistic diseases associated with
AIDS led to presumptive diagnosis, diagnostic chaos and verbal autopsy that have sparked
an international ongoing debate that remains unresolved.
2.2 AIDS WITHOUT HIV
Due to increase of alarming predictions and AIDS incidences, it was crucial to distinguish
between a virus (HIV) and a syndrome (AIDS) to recognize how ambiguous definitions
have helped spawn misinformation about AIDS. To distinguish between a HIV antibody
test and an actual AIDS case, the Ganteng Health Department, in 1997, decided to
henceforth use the term ‘HIV infection’ to include every stage of infection and disease.
The CDC initially suspected that AIDS was caused by drugs as the syndrome was most
prevalent in the gay community. Recognized as Gay Related Immune Deficiency or GRID,
the condition mostly afflicted male homosexuals in major cities like New York and San
Francisco, who were constantly exposed to sexually transmitted disease, bacterial
infections and indiscriminate use of IV drugs.
Soon, other groups such as hemophiliacs, drug addicts and the third world poor became
affected with AIDS and the various opportunistic diseases associated with it. These risk
groups shared similar systems of immune suppression caused by multiple co-factors
including drug use, bacterial infection, unsafe sexual practices, poor nutrition, pollution and
unsanitary living conditions.
Prior to the discovery of HIV in 1984, many of these various immunosuppressant factors
were still being investigated, but due to the firm believe in the HIV hypothesis, much
research was discontinued.
In recent years, there have been a growing number of cases of severe immune suppression
clinically identical to AIDS but do not test positive for HIV and who are HIV positive but
do not develop AIDS.
It was believed that HIV also destroys T4 cells; one of the markers for AIDS but studies
suggests that high T4 counts do not necessarily correspond with health. Researchers have
found people whose T4 counts are almost non-existent who show no signs of disease.
Furthermore, there is no proof that low T4 counts are sufficient to produce AIDS
symptoms. AIDS causes a decline in CD4 counts, another marker for immune suppression,
used by virtually all AIDS therapies. Researchers now stress that the CD4 is no longer a
reliable marker for clinical progression of the disease because certain drugs have raised
CD4 counts with no improvement to health.
Finally, the chemical interactions or chemistry of most people with AIDS and those at risk
does not resemble a ‘typical response to a single viral agent’ and is far closer to resembling
a ‘stress response’.
Although, the orthodox AIDS establishment remains firm in its belief that HIV causes
AIDS, they now admit that HIV alone cannot cause AIDS. Recent studies and the
overwhelming evidence that debunks the HIV hypothesis including the immense pressure
by peers and the media have caused the CDC to reevaluate their stance on the AIDS debate.
The CDC has now settled on a new name for the ‘mysterious disease’ calling it Idiopathic9
(cause of disease unknown) CD-4 Lymphocytopenia10 or ICL.
Idiopathic is an adjective used primarily in medicine meaning arising spontaneously or from an obscure
or unknown cause
Lymphocytopenia is the condition of having an abnormal low level of white blood cell in the blood
2.3 WORLD STATISTICS ON HIV CASES
• The first HIV case was reported in the USA in 1981. There was a high incidence of
the disease in homosexual males and intravenous drug users.
• 1985 – The test for the HIV antibodies becomes available.
• In 1996, 18 million people in the world were infected with HIV.
• In the USA, AIDS is the first leading cause of death among men aged 25-44 and the
third leading cause for women in that same age bracket.
• 2005 – UNAIDS – 40.3 million people are infected with HIV worldwide.
• 2005 – Number of infected people totaled 4.9 million
• 2005 – Death toll was 3.1 million
• December 2005 – 46% of all adults who were infected with HIV were women. 57%
were from Sub-Saharan Africa.
• In Africa there are 12 million AIDS orphans.
• Since 1981, AIDS has killed more than 25 million people.
• The age bracket of 15-24 accounts for half of the new HIV infections worldwide.
• More than 6000 people are infected everyday.
• 6.5 million People in developing and transitional countries need HIV antiretroviral
therapy, only 1 million receive treatment.
2.4 ROUTES OF TRANSMISSION
This virus can be transmitted through any form of sexual intercourse. The use of condoms
greatly reduces the risk of contracting this virus, but it does not prevent it. There have been
situation where condoms have ruptured, leaving the person at risk of contracting the virus.
There have been studies on the effectiveness of spermicides11 in killing the virus, but these
have not been conclusive.
It can also be contracted by the percutaneous12 inoculation of blood or any other infected
materials. This can happen via blood transfusions and through the sharing of contaminated
needles by users of intravenous drugs.
HIV can also be transmitted from the mother to her child. This can happen while the child
is in the womb, via the placenta, during birth, with the tearing of the tissues of the vagina
and the presence of blood as well as the child's underdeveloped immune system, as well as
after the child has been born, through the breast milk. The presence of the virus is low in
breast milk, but there is still the slight chance that transmission can occur.
Spermicides are chemical products inserted in a woman's vagina before sex that inactivate or kill sperm.
Percutaneous pertains to any medical procedure where access to inner organs or other tissue is done via
needle-puncture of the skin, rather than by using an "open" approach where inner organs or tissue are
2.5 INCUBATION PERIOD
This varies greatly, but on average, the time span of exposure to the virus and the
appearance of an AIDS related opportunistic disease, is 11 years.
The window period (the period where the virus replicates in the blood, but cannot be
detected by blood tests) is roughly about 90 days. This period is quite critical as there is the
high possibility of spreading the disease, but there is not laboratory test that can be done to
detect the antibodies. Infected individuals can continue to spread the disease unknowingly.
People look healthy and there are usually no signs of symptoms, apart from flu-like
symptoms, that could raise suspicion.
The presence of the HIV antibodies is usually detected and confirmed by a serological test,
especially if there is a suspicion of having contracted the virus. These serological tests are
also important if there are cases of bacterial pneumonia, tuberculosis, oral candidiasis13,
cytopenia14, Kaposi's sarcoma and Pneumocyctis carinii pneumonia.
The diagnosis of the acute retroviral syndrome requires the direct measurement of viral
constituents, such as, the viral p24 antigen, viral culture of the amplification of viral nucleic
acids. The ELISA (Enzyme Linked Immunosorbent Assay) is the test that is used to screen
persons with suspected HIV infection, six to 12 weeks after the infection. It detects
antibodies to HIV core proteins and surface glycoproteins16. It is a highly sensitive test, but
it is still possible to generate false positive results, especially in those patients who have
Candidiasis commonly called yeast infection or thrush, is a fungal infection
Cytopenia is a reduction in the number of blood cells.
A positive ELISA test is further confirmed with a test called the Western Blot. This test is
more specific. The HIV antigens are separated by electrophoresis and specific antibodies in
the serum bind to viral antigens and can be visualized.
HIV serology is strongly recommended for people who have STD's (Sexually Transmitted
Diseases), who engage in high risk behavior, who have HIV related illnesses, who have had
sexual contact with an infected person, and who have had blood transfusions between 1977
and 1985, those who are contemplating pregnancy and those in situations which the
contraction of HIV could complicate.
2.7 Philosophy and Concept of Natural Healthcare and Medicine in the treatment
and management of HIV/AIDS or Idiopathic CD-4 Lymphoctopenia (ICL)
The philosophy of Natural Healthcare and Medicine subscribes to the belief that the cosmic
energy is the creative essence and life empowering force of the universe or cosmos. This
energy, which is described as having no beginning and no end, through its own inherent
natural intelligence, assumes various forms, changes its form continuously from the energy
dimension to the material dimension. In its smallest basic form it tends to be either wave–
like or form–like. The energy itself is neither created nor destroyed but takes various forms
and moves in waves, such as electromagnetic waves, light waves and other unknown means
yet to be fully discovered.
The cosmic energy assumes life forms which vary from very small subatomic particles to
minerals, to plants, animals and human beings. These life forms especially that which is
organic in nature, recreates itself to perpetuate its existence. A virus are one of the simplest
yet very powerful forms of organic life and being a member of the myriad of living forms
created by nature, survives by sharing its niche with other life forms. For instance the
Hepatitis B Virus survives in the human body only and perpetuates itself by moving from
one human being to another human being through blood and body fluids.
Essentially there is a dynamic ecological interrelatedness and balance among the living
organisms that make up the world of living things. The life forms display progressive
adaptation through a process of mutation which can result in either better survival of the
mutated form or lose out by its inability to survive. Major ecological changes in the world
or the cosmos may disrupt the numerical balance of live forms. Some may not be able to
adapt to the drastic changes brought about my natural disasters or changes in the climate.
Such life forms may just go extinct or undergo subtle mutation, enabling it to adapt to new
niches as changes takes place in the primary, secondary or tertiary niche of existence.
For the Human immunodeficiency virus (HIV) the primary niche is the human body. If the
virus gets into the human body, it uses its survival and reproductive intelligence to sense,
understand the host's intelligence, especially its defense mechanisms, and outsmart the
system and the parts that are involved in attacking and destroying the invading virus.
In order to understand how the Human immunodeficiency virus (HIV) operates within the
host, one must understand how it exercises its inherent intelligence, to sense and recognize
the elements of its niche, the terrain of the hosts which it uses to travel within the niche and
how it uses the information it has sought to develop its strategy to colonize the niche,
perpetuate its reproduction and growth, using the host’s materials and resources. Dealing
with physical entities such as enzymes, cells and other proteins which are within the host’s
niche alone is insufficient to understand the full operative activity of the virus in its effort
to overpower and colonize the host.
The sensing mechanism, and the nature of how viral information system travels to the
various parts of the host, how it copies, analyses and understand the host’s defense system
and parts, these invisible non physical processes must be recognized fully if one wants to
disrupt the viral attacking activity.
Natural Healthcare and Medicine attempts to recognize and understand the physically
invisible expression of the viral intelligence in its attempt to convert the host’s materials as
its nutrient for replication. What is to be visualized is to imaginatively understand the
interchange of viral and host energy in the interactive survival of the two competing or
fighting life forms within the human organism. The virus as the invading life form and the
human immune cells as the defending life form, in a preset terrain where the inherent
intelligence of each life form expresses itself through multi–directional movement of
information, transmitted and received, for each one to develop their respective offensive
response. The nature of this instructive and feedback information, its dynamics and the
terrain must be understood if a disruption in the viral operative activity is desired. A way
must be devised to disrupt the flow of information, its sensing mechanisms and also to
change the terrain.
Disrupting the terrain by flooding the viral pathway with thousands of natural substances,
with a view towards misleading the virus-sensing mechanism, intercepting its information
transmission pathways, creating natural decoys, all these will have a confounding effect on
the viral expression of its intelligence; it may also affect the host’s immune response. But
from the clinical outcome one can conclude whether the disruption favors the virus or the
host. The thousands of bioactive principles found in the Highly Active Micro-Nutrient
Wholesome Formulae (HAMNWF), transform the terrain and disrupt the permanent routes
The aim of natural medicine therapy is to disturb the terrain, its travel route and intercept
the flow of viral information which is generated from the expression of the viral
intelligence in trying to overpower the host’s defense cells. This change in the terrain
confounds and confuses the virus which can curb its growth process, thus slowing down its
replication. Once this happens the host’s defense is in a better and a more favorable
position to mount an immunological attack on the virus.
How does a natural medicine product thwart the HIV virus? The postulation is based on the
assumption that if thousands of safe bioactive substances in HAMNWF16 in ppm
HAMNWF- Highly Active Micro-Nutrient Wholesome Formulae
quantities are released into the blood stream, the appearance of the terrain of the virus will
be transformed, by all the bioactive substances moving in its pathway. This change in the
nature of the virus terrain confuses the viral intelligence, disturbs its route, thwarts its
replication rate and slows down its attack on the host’s defense cells. The scientific basis is
that one type of compound, aiming to attack the virus, as in the allopathic viewpoint is
insufficient to effect a transformational change in the terrain familiar to the virus. For that
reason allopathy has no totally safe and effective medicine to disarm or confuse the HIV
The clinical findings of the case studies in this paper seems to be consistent with the
postulated hypothesis that multi-molecular HAMNWF treatment approach to disorientate
the viral intelligence, provides an effective and safe therapy for immunologically
confirmed HIV/AIDS cases. More than 20,000 bioactive components contained in ppm
quantities in the products used renders the virus pathologically less virulent and allow the
body's immune system to keep the invading virus at bay. The superiority of the treatment is
its safety profile as compared to the very severe side effects of anti- retroviral drugs
currently used in allopathic conventional HIV /AIDS therapy.
2.8 COMPARATIVE TREATMENT
Up to the present time of the research and writing of this paper, there has been no total cure
for HIV/AIDS. It has been treated in two different ways:
1. By the management of secondary infections or malignancies associated with AIDS
2. By the treatment of HIV itself.
The treatment of HIV involves the utilization of various treatments. These forms of
treatment can be either allopathic or chemical in nature or natural and free of chemicals. In
this paper, we will be looking at the advantages and disadvantages leading allopathic
treatments as well as the naturopathic treatments that have been developed and are
currently being used at AK Pharmacy and Naturopathy Centre and AMRI-Asia.
2.8.1 ALLOPATHIC TREATMENT
As mentioned before, there are two main approaches that both allopathic and naturopathic
medicine takes in the treatment of HIV/AIDS - the management of malignant diseases
associated with the AIDS and the treatment of HIV. The former treatment deals with
maintaining the strength of the body. This is done through proper nutrition and the general
building up of the immune system so that the infection does not set in. Medications are also
given to treat the opportunistic diseases e.g. Zovirax-a drug which is given for the treatment
of herpes. It slows the growth and spread of the herpes virus so that the body can fight
off the infection. Zovirax causes allergic reaction such as hives; difficulty breathing;
swelling of face, lips, tongue, or throat. It also causes serious side effects such as urinating
less than usual or not at all, easy bruising or bleeding; and unusual weakness.
With the treatment of HIV itself, it is a little different. This approach attempts to stop the
replication of the virus. In order for viral replication to take place, there are certain viral
enzymes that need to be present.
The enzyme reverse transcriptase promotes the formation of viral DNA (Deoxyribonucleic
Acid) from viral RNA (Ribonucleic Acid). The first effective treatment for HIV was a drug
called AZT (Azidothymidine). It is also known as Zidovudine. This drug is a reverse
transcriptase inhibitor - it prevents the formation of viral DNA from viral RNA. This drug
can delay the onset of full blown AIDS, but it does not increase the survival time of patients.
It has been found however, that the number of babies who contract HIV from mothers is
dramatically reduced by giving mothers AZT during pregnancy and to the babies following
birth. The side effects of this drug are a decrease of red or white blood cells, especially when
taken in the later stages of the disease. Some may also cause inflammation of the pancreas
and painful nerve damage. There have been reports of complications and other severe
reactions, including death, to some of the antiretroviral drugs when used alone or in
combination. After six to 18 months of treatment with this drug, HIV mutates to become
resistant to AZT. Other drugs such as Dideoxyinosine (DDI) have been given to patients who
are resistant to AZT.
Other drugs such as Ritonavir and Indinavir inhibit the enzyme protease or also known as
protease inhibitor. This enzyme breaks large viral proteins into smaller ones which are
incorporated into the new HIV. The most common side effects associated with protease
inhibitors include nausea, diarrhea, and other gastrointestinal symptoms. In addition, protease
inhibitors can interact with other drugs resulting in serious side effects. Fuzeon may also
cause severe allergic reactions such as pneumonia, trouble breathing, chills and fever, skin
rash, blood in urine, vomiting, and low blood pressure. Local skin reactions are also possible
since it is given as an injection underneath the skin.
The current treatment for HIV suppression is a combination of three drugs - two reverse
transcriptase inhibitors and one protease inhibitor. There is a less likely possibility that a
person will develop resistance to all three drugs. This combination is effective in reducing
the death rate and partially restoring health in some individuals. There is still much research
being done on the enzyme integrase. It inserts the viral DNA into the DNA of the host cell.
The measurement of the viral load, or the quantity of HIV present in a millilitre of blood.
They have found that the higher the viral load, the faster the person will develop full blown
AIDS. Attempts are currently being made to match the drug treatment to the viral load of the
The primary goal of antiretroviral therapy for human immunodeficiency virus (HIV)
infection is suppression of viral replication. Evidence indicates that the optimal way to
achieve this goal is by initiating combination therapy with two or more antiretroviral agents.
Using allopathic antiretroviral therapy drugs has shown to increase the CD4+ counts, if the
therapy is started in the early stages of the disease when the CD4+ counts are higher to start
with. There have been, however, complications with resistance, long term adverse effects,
drug interactions and decreased compliance use. The general consensus of medical personnel
is that ART should be started if the patient has a CD4+ count of lesser than 350 u/L.
Some other medical professionals prefer to look at treatment using the viral load of the
patient as opposed to the CD4+ count. When this is used, the patient is considered for
treatment with a viral load of higher than 5,000 to 20,000 copies per ml, regardless of the
CD4+ count. Selection of the combination regimen must take into account the patient's prior
history of antiretroviral use, the side effects of these agents and drug-drug interactions that
occur among these agents and with other drugs as well. Because of the potential for viral
resistance, non-nucleoside reverse transcriptase inhibitors and protease inhibitors should only
be used in combination therapy.
There is still some speculation as to whether or not ARTI improves the survival in patients
with CD4+ cell counts in the range of 500u/L. Patients with high CD4+ counts (greater than
500) are at low risk of clinical progression of the disease in the ensuing three years.
In a one-year study of HIV-infected people, infusions of the immune system protein
interleukin-2 (IL-2) have resulted in dramatic and sustained increases in the primary immune
system cells depleted during HIV infection, according to investigators at the National
Institutes of Health (NIH).
In the study, patients randomly assigned to receive IL-2 plus standard antiretroviral therapy
had mean CD4+ T cell counts that increased from 428 cells per cubic millimeter of blood
(mm3) at baseline to 916cells/mm3 at month 12. Among patients randomly assigned to
receive standard antiretroviral therapy alone, mean CD4+ T cell counts decreased from
406cells/mm3 to 349cells/mm3. CD4+ T cells are the main targets of HIV; the progressive
loss of these cells leads to the symptoms of the acquired immunodeficiency syndrome
Significantly, the amount of HIV in the blood of study patients receiving IL-2 therapy
remained stable over time. Previous studies had shown that IL-2 treatment can result in
transient bursts of virus production in some patients, but the current data clearly indicate that
these bursts do not lead to sustained increases in viral load.
In addition, the side effects of IL-2 infusions in the current study were much less severe than
those seen in previous studies using higher doses of intravenous IL-2.
"Our study has clearly demonstrated that IL-2 therapy can have a substantial positive impact
on the major immunologic abnormality associated with HIV infection, the loss of CD4+ T
cells, without leading to an overall increase in the level of HIV in the bloodstream or to
unmanageable toxicities," says Dr. Kovacs.
Despite flu-like symptoms and other side effects during IL-2 infusions, patients in the study
reported feeling as well overall as patients not receiving IL-2, according to a quality of life
analysis presented at the 11th International Conference on AIDS in Vancouver, B.C.
2.8.2 STUDY DETAILS
In the study, 60 patients with baseline CD4+ T cell counts above 200/mm3 of blood were
randomly assigned to receive IL-2 plus licensed antiretroviral therapy, or antiretroviral
therapy alone. IL-2 was administered at a starting dose of 18million International Units (IU)
a day for five days every two months. The dose was reduced as needed; the mean dose used
in the latter part of the study was approximately 8 million IU/day.
The most common side effects during IL-2 administration were fatigue or malaise, reported
by patients during 44 percent of the five-day treatment cycles, and headache, reported during
7 percent of treatment cycles. The most common laboratory abnormality, seen during 8
percent of the treatment cycles, was an elevation in bilirubin levels, indicating an effect on
the liver. The elevations were not accompanied by clinical symptoms, and levels returned to
normal after the treatment period. The investigators note that toxicities decreased in
frequency during later rounds of treatment as IL-2 dosages were reduced.
In an extension phase of the trial, the investigators found that increases in CD4+ T cells
could be sustained for more than two years by continuing to administer IL-2 on an
individualized schedule. In five patients, CD4+ T cell counts remained over 1000/mm3 for at
least 18 months after discontinuing IL-2.
"To date, no combination of antiretroviral agents has been shown capable of inducing
increases in CD4+ T cell counts of this magnitude or duration," the authors write.
Because IL-2 targets the immune system rather than HIV itself, viral mutations should not
reduce its effectiveness, the investigators note. In contrast, resistance to antiretroviral drugs
occurs because of HIV's high rate of mutation.
"The lack of resistance to IL-2 helps explain why some patients have continued to respond
to IL-2 therapy even 50 months after beginning therapy," says Dr. Kovacs.
While the current study of IL-2 enrolled only patients with CD4+ T cell counts above
200/mm3, additional Phase II work in NIAID's AIDS Clinical Trials Group is being
planned in patients with more advanced disease. Ronald T. Mitsuyasu, M.D., director of the
UCLA Center for AIDS Research and Education and associate professor at the UCLA
School of Medicine, is focusing his efforts on patients with lower CD4+ T cell counts, and
will assess IL-2 given with antiretroviral regimens that include a protease inhibitor.
The NIH investigators currently are working with scientific colleagues in the United States
and abroad to develop a Phase III strategy to determine whether the increases in CD4+ T
cells achieved with IL-2 therapy will translate to fewer AIDS-related complications and
improved survival for HIV-infected people.
2.8.3 SIDE EFFECTS OF HAART
Adverse effects of antiretroviral drugs vary by drug, by ethnicity, and by individual, and by
interaction with other drugs, including alcohol. Hypersensitivity to some drugs may also
occur in some individuals. The following list is not complete, but includes several of the
common adverse effects experienced by patients taking some antiretroviral drugs:
• Abdominal pain
• Dizziness (Vertigo)
• Fanconi syndrome
• Hypercholesterolemia (Dyslipidemia, Hyperlipidemia, high cholesterol)
• Hyperpigmentation (of nails, palms, or soles)
• Ingrown nails
• Liver failure
• Mental confusion
• Mitochondrial toxicity
• Myalgic Encephalomyelitis (chronic fatigue syndrome)
• Oral ulcers
• Paresthesia (numbness)
• Peripheral neuropathy
• Renal failure or insufficiency
• Somnolence (drowsiness)
• Stevens-Johnson syndrome
• Change in taste perception
• Xeroderma (dry skin)
• Xerostomia (dry mouth)
• Diarrhea and other gastrointestinal symptoms.
• Harmful drug interactions resulting in serious side effects.
• Allergic reactions such as pneumonia, trouble breathing, chills and fever.
• Skin rash.
• Blood in urine.
• Low blood pressure.
• Local skin reactions are also possible since it is given as an injection underneath the
* The long term effects of these allopathic drugs are not known.
Cost is another factor that plays an important role in the treatment of HIV/AIDS. There are
some people who can afford the treatment and others who cannot. In countries like Guyana,
South America, the AIDS patients are not required to pay for the medications because they
are manufactured in the country. In other countries, the cost of the medicine is high and this
can be a factor in the decision of people to undergo the antiretroviral therapy.
“Chequer said the annual cost of treating a patient with antiretroviral drugs reached
$2500 in 2004, $1150 more than in 2003 because of the high cost of medications.”
- Reuters, June 11th, 2004.
“Abbott last December raised the price of a 100-milligram Norvir capsule to $8.57 from
$1.71. The company said the price hike was necessary to reflect the drug's true value and
to help fund future research. AIDS activists and some physicians called the higher price
- Reuters, June 11th 2004.
“The wholesale prices for a month's treatment of Norvir were raised from $265 from $54.
The special booster role that Norvir plays already usually cost between $800 and $1,300 a
- V. Fuhrmans, the Wall Street Journal, December 19th 2003.
“Reyataz's wholesale price is $684 a month and Lexiva wholesales for $480 a month,
Kaletra prices at $580 a month wholesale.”
- V. Fuhrmans, the Wall Street Journal, December 19th 2003.
All the prices that were quoted above were all in USD$. It can be seen and concluded that
for HIV antiretroviral therapy, the prices for treatment, using allopathic drugs ranges from
USD$ 680 to $480 monthly.
• AZT can delay the onset of full blown AIDS, but it does not increase the survival
time of patients.
• The number of babies who contract HIV from mothers is dramatically reduced by
giving mothers AZT during pregnancy and to the babies following birth.
• After six to 18 months of treatment AZT, HIV mutates to become resistant to it.
Other drugs such as Dideoxyinosine (DDI) have been given to patients who are
resistant to AZT.
• Three drugs are usually given in combination so that there is a lesser chance of the
virus becoming immune to the individual drugs.
2.9 NATUROPATHIC TREATMENT
There are many naturopathic treatments that can be taken to alleviate some of the
symptoms of HIV/AIDS. In this study, we will be focusing on the treatments used and
developed at AK Pharmacy and Naturopathy Centre, Malaysia.
The treatment that was given to the patient was all made from spices, vitamins, cereals and
beans. The treatments that were given were given in capsule form. This was done to
facilitate the way the medicine was taken. The treatment was made up of four HAMNWF
SBCV Mas Ayu Treatment for HIV/AIDS, its uses and posology
Mas Amirtha 1 1 1
-- Regulation of the biochemical and physiological balance of the body
-- Improves the quality and quantity of blood cells
-- Optimizes immunity and maintains a disease refusal state
-- Regulates blood fats, carbohydrate and protein metabolism
-- Adjunct for kidney function maintenance
-- Reduces uric and other acids which cause renal and gall stones
-- Improves blood circulation and vision
-- Antiviral, flu, dengue and blood borne virus.
--Adjunct for fever caused by viral and bacterial infection
-- Iron deficiency anemia
Mas Aki 1 1 1
-- For energy, strength and stamina
-- Improvement of blood circulation
-- Improvement of metabolism of absorbed food
-- For carbohydrate metabolism
Mas Semalu 1 1 1
-- Prevents urinary tract infection
-- Adjunct for the treatment of gall stones and renal stones
-- Natural mild antibiotic
-- Adjunct for viral fever
Mas Tenang 0 0 1
-- Reduces mental and physical stress
-- Regulates blood pressure
-- Prevents tension headaches (migraine)
-- Improves interpersonal communication
Mas Neem Plus 1 1 1
-- This is a natural antiviral treatment
-- Tradisionally used for viral and bacterial infections.
Mas Collustrum 1 1 1
-- Is the first milk which is rich in antibodies, enriched with extra ingredients (spices)
for normal metabolism, growth and development.
-- It is an excellent product to built immunity
-- It also assists in regeneration and improves normal growth of aged or injured
muscles, bone cartilages, skin collagen and nerve tissue.
Goats Milk Daily
-- It is a renewable source of animal fats with the magic 8 essential amino acids that
the body cannot produce on its own.
-- Excellent for a healthy gut
-- Goat’s milk contains 13 percent calcium, 25 percent vitamin B-6, 47
percent vitamin A, 134 percent potassium, and three times niacin. It
is also four times higher in copper. Goat's milk also contains 27 percent more of the
Pure Natural Honey Daily
-- Honey is one of nature’s most wonderful foods.
-- Eliminate most of the free radicals in body.
2.9.1 Products Used for the Treatment and Management of HIV/AIDS
Mas Ayu- Amirtha – MOH: MAL05041853TC
Mas Ayu- Mas Aki - MOH: MAL05041851TC
KJH Mas Ayu- Neem – (FOOD)
Mas Ayu- Semalu – MOH – MAL05041863TC
Mas Ayu- Tenang – MOH – MAL05041856TC
2.9.2 SIDE EFFECTS OF NATURAL PRODUCT
The naturopathic products used by AK Pharmacy and Naturopathy Centre are virtually
side-effect free. Since the product are made from SBCV products (spices, beans, cereals
and vitamins), which all containing fibrous components, it is expected that the side –effect
would be a purging of the body in the form of a mild diarrhea. This side effect is not
common, but it has been experienced by some patients. It stops once the body has come to
a balance with the treatment that is being put into it. This process takes roughly two days.
The products used in the naturopathic treatment of dengue are all manufactured from
natural substances, from plants and seeds that have been part of our daily cooking recipes
from the beginning of time. In the treatment that is given, patients will find something for
the pain, something for the fevers and something for the general malaise and weakness that
they are feeling. The combinations used in the treatment are all natural, with the ingredients
used, being derived from everyday spices, beans, cereals and vitamins. The products are
already combined and come in a capsule form, making them easier to take. The patients
begin to feel better in a shorter period of time on the natural treatment described in this
case. There is a quicker alleviation of the aches and pains and those who are hospitalized
are discharged sooner.
The cost of naturopathic treatment for HIV/AIDS, using the products developed by AK
Pharmacy in Malaysia is as follows:
Mas Amirtha – 250mg – RM 41 x 3 = RM 123
Mas Aki – 250 – RM 35 x 3 = RM 105
Mas Semalu – 250mg – RM35 x 3 = RM 105
Neem – 250mg – RM 25 x 3 = RM 75
Mas Tenang – 250mg – RM 23 x 3 = RM 69
TOTAL: RM 477
It has been estimated that with taking one of each of these capsules three times a day that
the need would be for 90 capsules a month of each product.
2.9.4 EFFECTIVENESS OF HAMNWF
• Natural medicines do not need to be combined with specific medications in order to
• They are easy to take – they do not involve the use of needles or anything so traumatic.
• There is no exchange of fluids involved, so care givers do not need to feel like they are
being put at risk of contracting the virus.
• They have managed to raise the CD4+ count.
• There are no side effects.
2.10 COMPARATIVE ANALYSIS OF THE TWO TREATMENTS
Here we have a table showing the comparison of the two types of treatments and their
advantages as well as their disadvantages.
• Old drugs may not • This treatment has
be as effective as proven to be
new discoveries are effective – the
made. CD4+ count was
• Side effects can be significantly raised,
more dangerous than without using any of
the disease itself the current
(Refer comparative allopathic anti-
analysis of side retroviral drugs.
• The cost for • The cost for
treatment ranges treatment is USD$
from UDS$ 684 to 195 monthly.
USD$ 480 monthly.
• Lot of side effects • There are no side
that can be stressful effects, so the
Emotional to deal with. patient feels better.
• Emotional trauma • Natural medicine
because of the makes it a point to
needles that is treat the patient as
sometimes required well as the disease.
for taking the drug.
2.11 PREVENTION OF HIV/AIDS
Governments all around the world have to deal with the epidemic crisis of HIV/AIDS.
Millions of dollars every year are spent on HIV education. Billboards are put up, pamphlets
are made a distributed, sex education classes are help in high schools and universities, but
as the statistics show us, the number of new HIV infections continues to rise.
There must be something else that we are over looking or some other factors that are
involved – why are there so many new cases, especially in the 15 – 24 year old bracket, if
we are spending so much money for a good HIV education for the population?
The most common pneumonic that is used throughout the world for HIV/AIDS prevention
are the ABC’s of HIV/AIDS. We are told to Abstain, Be Faithful and to Condomise. This is
an effective way of remembering what we are supposed to do, but sometimes it is not
always as easy as that.
This is the complete refraining of engaging in any form of sexual activity. This is the best
way to prevent HIV, through sex. If there is no sex, there can be no exchange of semen of
vaginal secretions and thusly the virus cannot be transmitted, via sex. This however, is a
method which requires a great deal of self control. It is not easy to refrain from having
sexual intercourse, especially if one knows the feelings involved. For many teenagers and
young adults, sex is seen as a spontaneous thing. Spontaneity does not usually involve
What about cases where people are raped? They are forced to have sex. In most rape cases,
protection from HIV and other STD’s is usually not the foremost thought in someone’s
As mentioned earlier on in this study, HIV can be transmitted via the blood. If a person has
decided that they will abstain from having sex, but go to the hospital or clinic where they
receive infected blood, or they happen to share a needle with an infected person what
happens then? It is important to understand that HIV is not just confined to the parameters
of the ABC’s. If you decide to abstain from sex, sometimes that is not enough to prevent
ii. Being Faithful
This is a method which is usually practiced between two people who are in a monogamous
relationship, who trust both themselves as well as the other person in the relationship. In a
Utopian society, this would be an ideal way to curb the spread of the virus, but we do not
live in a perfect world. Two people who love and respect each other will remain faithful. It
is common for husbands and wives to engage in sexual acts without the use of condoms.
This is done to have children and also because of the love and trust mentioned before. If
one partner is unfaithful, there is a great risk and extreme likelihood that the virus will be
passed on and can infect the negative person. This is taken to another level if the couple
decides to have children. If there is no knowledge of the infidelity, then there will be no
need to have an HIV test done. If they do have children, there is a chance that they too
could become infected.
The whole issue of being faithful is further complicated if the person has a job where he or
she is apart from the other. Truck drivers, businessmen, etc, are all professions that leave a
window open for infection in this way. Financial security is another reason for infidelity.
Prostitution is the oldest trade in the world. It guarantees money and does not require a
degree of many years of schooling. For some people, this is the fastest way to make money
to pay the bills and to have some form of sustenance. For them, the risk of getting evicted
or of having the power cut is greater and means more to them than contracting HIV.
Getting evicted means having nowhere to go and nothing to eat – this is something that
people need to feel secure. They are tangible, touchable things that they know that they
need. HIV to them seems to be something abstract.
This is another method that is taught to us – to use condoms if we are going to engage in
sexual acts. A condom is made of a thin material called latex. It is pre-packed and is
usually covered with a spermicidal jelly. It is a sheath that is rolled over the entire length of
the erect penis before sexual intercourse and then is removed immediately after ejaculation.
There are female condoms, but they are not as popular and as easily available as the male
ones. Now they are being manufactured in different sizes, colors, flavors and textures.
Condoms are readily available. In most high schools, universities, clubs, restaurants, hotels
and rest stops in many countries, they can be found in dispensers or they can be bought.
They are light and easily carried.
There is some embarrassment in the buying of condoms, especially in females and
adolescent males. Society should do its best to eliminate this stigma – that is an
embarrassment to buy condoms. Some people prefer to do without, rather than to suffer the
embarrassment and buy them.
Since condoms are very delicate, care must be taken when putting them on and taking them
off. There have been cases where the condoms have broken during intercourse. In my
personal opinion, there are certain situations in which condoms will not function – if the
person is drunk, the condom may not be worn correctly. It can be put on too violently and
this may cause a rip or tear which can then lead to breakage.
The condom may come off in the act and the person may not realize it due to the fact that
he is drunk. In this case, using a condom is no different from not using one. Another
situation in which condoms may be of little or no use is if the person, either male or female,
happens to be allergic to latex or allergic to the spermicide that has been used in the
condoms. The spermicide will help to prevent a pregnancy if the condom breaks, but it will
not help in the prevention of contracting and STD or HIV. This is another situation where
using a condom would not have made a difference.
These are the three main ways that we are taught to protect ourselves from this virus, but
these are not the only ways in which we can become infected. The world is not a static
place and we need to keep our minds open to all possibilities.
There are some cultures which believe that the sharing of blood is one way to rejuvenate,
strengthen and keep people with us. It is also a way to pass on the virus. There are some
tribes in Kenya that practice this custom. A dying father will call his sons and ask them to
slit their wrists and there will be a transfer of blood from the father to the sons. There was
one such case where the father was dying of AIDS and he managed to infect his seven sons
because of this tradition. His sons in turn infected their wives and also the children that
they had following the infection. The last son was a “saved” man who was saving his
virginity for his wedding night. Customs like this is what is making this terrible virus
spread like wildfire throughout Africa.
People are told that sleeping with a virgin will cure them of this disease and that the
younger she is, the more potent the cure. Because of this, there have been thousands of
female infants who are raped by their uncles, cousins, brothers and neighbors, thinking that
they have just cured themselves.
Some countries have been caught between a rock and a hard place. Religious countries can
preach the law of abstinence and this may help in the spread of the virus in those countries,
but for others, religious law would be laughed at. How can you stop people from doing
what they have been doing for so long? Other, more progressive thinking countries have
started to look at things in a different way. They have come to the conclusion that if people
are going to continue to do what they have been doing, then the least that they can do is to
ensure that it is being done safely. Prostitutes are given free condoms and also receive free
STD tests and HIV tests. Intravenous drug users are given opportunities to change their
dirty, used needles for clean ones. For these people, prostitution and drug addiction may be
a way of life, the only thing that they know. It will not be that easy asking them to change
Ultimately, the prevention of HIV is based purely on individual choice. As humans we
have free will – the right to make our own decisions based on how we feel and how we
think. We know how the virus is spread, but we also know how we can prevent the spread.
HIV infection can be likened to two armies about to do battle, one in an open field and the
other in a walled city. The army that is inside the city, defending it has the walls as its
protection. If the invading army happens to entry the city, all is lost because the guards and
inhabitants of the city will have no where to run. Once the army has entered the city, it will
take it over. The key is not to let the army enter – to put up such a strong defense that there
is no possibility of entry.
2.12 CARE FOR HIV/AIDS PATIENTS
This can be difficult because of the social stigma and the lack of understanding of the
disease. Patients are often ostracized by society as well as family and friends. Society is
constantly changing the mental picture of the disease by the different awareness campaigns
and the recommendations that are given by people in authority, such as the government and
religious organizations. Everyone has an opinion as to what is right and acceptable and
what is not. It is important that the fact is separated from the fiction for the benefit of the
patient as well as his family and friends. This will help in destroying some of the stigma
surrounding the disease and may make acceptance in society easier.
There are new breakthroughs in the pharmaceutical world relating to HIV/AIDS - new
drugs are being developed and tested and old ones that are not as effective are being
discarded. The patient as well as the family should be aware of these developments. This
could affect his treatment, either financially or physically.
Most patients are given a very bleak and negative picture about life with the disease –
which is that they are going to die from an opportunistic illness or infections. This can
cause the patients to go into a state of depression. Depression will cause their already
depressed immune system to be put under more strain. This is not good for them
psychologically. They should be made to know that it is possible for them to live healthy,
productive and fulfilling lives despite having HIV. This is why counseling plays an
important part in the caring for HIV positive patients. It is important for them to be able to
share their feelings with people who not only understand what they are going through, but
also empathize with them.
For the caregivers, this can be an extremely gratifying and rewarding experience because of
the strong bonds that will be formed, but it can also be a very demanding, challenging and
sometimes a very nerve wracking experience.
It is important for these patients to have access to proper nutrition. Their immune systems
are already depressed. Proper nutrition will help to give the system the boost that it needs to
continue to function. Proper rest is also of paramount importance because of the strain that
is being put on the body. A sedentary life is not encouraged, but the patient should not
3.1 STUDY LOCATION
These sample groups of patients with HIV are those who come to the AK
Naturopathic Centre, which is located in Puchong to seek treatment.
A group of 100 HIV patients was chosen. These are those who sought alternative
natural treatment and choose the natural product for treatment. Half of them were those
under HAART (Highly Active Anti-Retroviral Therapy) and the rest were those who were
not under any medications. As such, there were 2 groups being studied.
1. 50 subject- On anti-retroviral drug
2. 50 subject- not on anti-retroviral drug
These patients were identified and selected carefully based on their sign and
symptoms. This research is based on the non-random sampling method, where to be
specific the purposive non-random sampling was used. This research particularly
conducted to see the effectiveness of SBCV in treating the HIV patients.
The study did not include a control group as it seems to be grossly unfair to the
patients being treated and the patients who are suffering from the disease without any
treatment. From the medical ethics and human rights, it seems unethical to do that. Hence
comparison with a control group was not conducted for this study.
3.3 METHODOLOGY OF THE STUDY
The method which was used in this study is basically a real time prospective study on HIV
patients who sought treatment at the AK Naturopathic Center.
1. A sample group of HIV patients was identified. These patients are those who come
to seek treatment from the naturopathic centre.
2. A survey was conducted thorough verbal interviews with patients directly and with
the founder of naturopathic centre.
Single or double blind controlled studies cannot be conducted on HIV patients, the primary
clinical objective is to arrest and reverse the infection in the shortest time possible.
• Each referred case was documented with information provided by the person who
came to collect the natural products for treatment.
• Follow up documentation on the progress of the patient was documented from the
information given by the person administering the products supported by periodic
blood reports provided.
• The changes in the symptoms and the clinical conditions and clinical outcome of
the treatment was recorded and documented as well.
• The type of treatment provided at the hospital was also recorded.
CASE STUDY 1
A 49- year old woman, named Parameswary was detected of having HIV Positive. She
was detected of HIV in 1997 from University Malaya Hospital. She contracted the disease
via her husband. She had symptoms of fatigue, weakness and weight lost. She was not
under any antiretroviral drugs. Madam Parameswary started Mas Ayu products on March
Madam Parameswary with Prof.
AK October 2007. Her case was followed up very closely by the naturopathic centre.
Date CD4 Count: Viral load.
03.02 04 NA 103 copies
25.03 05 NA 1250 copies
02.06 05 315 NA
24.03 06 569 19,200
Aug. 2007 NA NA
After the administration of Mas Ayu products Mdm. Parameswary’s health improved.
Her weight, stamina and strength improved, and she was getting into her normal life that
she used to have before contracting the disease. The level of her CD4 count also increased.
The study proved that CD4 count is not the absolute parameter for indication of the status
and HIV/AIDS of a person. Other mechanism of immunological defense has developed
with the aid of Mas Ayu product. Now Mdm. Paameswary is in good health and
continuously administering Mas Ayu products.
Prof. AK visited the patient in Alor Star Aug.
2007. She looked very healthy, and no sign of opportunistic infections.
CASE STUDY 2
A 43- year old male named Doraisamy became weak and developed swelling together with
abscess at the lymph nodes of his neck during March 2005 when he was diagnosed of
having HIV/AIDS. He sought treatment at Hospital Kuantan where he was diagnosed with
tuberculosis (TB), secondary to HIV/ AIDS. He was then treated for TB with Anti-
Tuberculosis drug. He was also referred to HIV clinic in Kuantan Hospital for the
management of AIDS. His CD4 count was reported to be 7 per Mic.l. Mr. Doraisamy was
later referred to naturopathic centre in March 2005 by one of the Medical Lab Technologist
from Hospital Kuantan. During the SBCV treatment the patient was not under any
The patient was put on SBCV treatment in March 2005.
MAS AMIRTHA 111
MAS SEMALU 111
MAS NEEM 111
MAS AKI 111
MAS TENANG 111
MAS KOLOSTRUM 1 01
GOATS MILK Daily
PURE HONEY Daily
FOLLOW UP ANALYSIS
SBCV treatment started in March 2007. His abscess healed rapidly and his health
improved. TB cleared completely and his health improved where he also did not have any
opportunistic infection. His weight, stamina and strength improved, and thus he could lead
a normal life. The doctors treating him were surprised with his health status. Because of his
unusual low CD4, but without any symptoms of AIDS the doctors in the hospital were
intrigued and a special team from HKL to investigated his case. The study proved that
CD4 count is not the absolute parameter for indication of the status and HIV/AIDS of a
person. Other mechanism of immunological defense has developed with the aid of Mas
AND STRONG DORAISAMY
A picture of Doraisamy looking, healthy, energetic and happy. Picture taken on 28th
Table showing viral load and CD4 count
DATE CD4 COUNT /UL viral load
MARCH 2005 7 NA
SEPTEMBER 2006 5 NA
SEPTEMBER 2007 4 16,000 COPIES
CASE STUDY 3
Medical/ Health History
A 54- year old male named Abdullah Abd Ghani was a drug addict and was diagnosed with
HIV/AIDS in 1994. He started on HAART in 2000 to control the viral count and for the
treatment of opportunistic infection. Since then he suffered from side effects such as severe
headache, migraine, weigh lost, pallor and tiredness. When this patient was interviewed by
research officers from AMRI Asia, he was looking skinny, very weak and his cheek bone
was protruding from the side effects of Anti-retroviral drug (LIPODYSTROPHY). Abdullah
was given the Mas Ayu natural nutritional therapy in April 2007
Physical Observation Before Mas Ayu Natural Treatment
– Cheek Bone Protruding
– Skin dry and pale
– Eyes looks Glazed
– Massive Headache
– Will sleep in the afternoon
– Sits slouched on the couch and barely answer the question
Mood and Mind
– Very negative
– Attention span is short
– Have repeat the question
– Very moody
Abdullah bin Abdul Ghani (Pengasih)
Mas Ayu natural nutritional therapy started in April 2007
MAS AMIRTHA 111
MAS SEMALU 111
MAS NEEM 111
MAS AKI 111
MAS TENANG 111
MAS KOLOSTRUM 1 01
GOATS MILK Daily
PURE HONEY Daily
The patient started the natural medication in April 2007. After 2 weeks of treatment, he was
relieved from headaches and gained more energy and stamina. He also increased in weight
and had a glowing skin. The patient also seemed to look happy and cheerful.
Natural Nutritional Treatment
SBCV Product Morning Noon Night
Amirtha 250mg caps. 1 1 1
Semalu 250mg caps. 1 1 1
Neem 250mg caps. 1 1 1
Aki 250mg caps. 1 1 1
Tenang 250mg caps. 1 1 1
Kolostrum 250mg caps. 1 0 1
Lab Test Result After the Administration of SBCV
WBC (4.3 – 11 /L) 6.2
RBC (3.8 – 5.5 /L) 5.10
Packed Cell Vol. (40 – 54%) 37
HB (13 – 18 g/dl) 12.3
Platelet (9150-400 x10^8 /L) 195
CASE STUDY 4
A 53- years old male has the history of being a drug addict and was diagnosed with HIV in
1993. He begins with HAART in 2002 in HKL. He had viral load of less than 50 copies in
June 2006. He also contracted Hepatitis C in 2006 and this is likely due to the side effects
of HAART. Ironically, HAART therapy also has been associated with a worsening or an
unmasking of occult opportunistic infections in patients with advanced AIDS. The patient
always looked tired and pale. His skin had a yellowish tinge to it. Due to the nature of his
work, he is required to travel frequently and that is taxing to his exhausted body. He also
suffers from insomnia. As he takes his anti-retroviral drugs in the morning, he will be flat
out for a couple of hours before he can function again.
Jaafar bin Daud
Natural Nutritional Treatment
SBCV* Products Morning Noon Night
Amirtha 250mg caps. 1 1 1
Semalu 250mg caps. 1 1 1
Neem 250mg caps. 1 1 1
Aki 250mg caps. 1 1 1
Tenang 250mg caps. 1 1 1
Kolostrum 250mg caps. 1 0 1
Goats Milk 1 0 0
Honey 1 0 0
Progress While on SBCV
His treatment started in April 2007. In the first week itself, he had noticed an
improvement in his mental function as well as energy level. His bowel movement
also improved. He no longer gets any side-effects from taking his anti-retroviral
drugs like he used to in the mornings and is able to function as per normal.
He stopped the treatment for a week when he underwent side effects from Pegasys,
a drug he was taking for Hepatitis C. Even in that week, his energy level managed
He is calmer and insomnia is getting less frequent. He now can nod off at around
midnight instead of waiting until 3:00 am. Energy level is now good even with a
more hectic daily schedule.
Lab Test Report
DATE/COMPONENT 4/1/07 27/4/07 26/5/07 15/11/07
WBC (4.3 – 11 /L) 3.20 2.83 3.80 4.60
RBC(3.8 – 5.5 /L) 3.00 3.08 3.10 3.50
Total RBC (RDW) 13.0 12.4 N/A N/A
(4.0 – 6.6 x10^12/L)
HB(13 – 18 g/dl) 11.6 12.2 12.5 14.5
Platelet(150-400 x10^8 /L) 146 98 187 181
There seem to be a lot of improvement from the physical and clinical changes of the patient
after the natural nutritional therapy. Hepatitis C was cleared and now he has developed
below detectable level under adjunct therapy together with pegasys.
CASE STUDY 5
A 37- year old male named Yusri was diagnosed with HIV/AIDS in 1997 and was on
HAART and later he was put on tuberculosis drugs and anti-hepatic drug. He was suffering
from serious side effects such as severe weight loss, poor health and energy from the drugs.
Yusri started Mas Ayu Product on 29.5.2007, and by June 2007 his health improved and he
regained his health and he could do his work and live his life without the debilitating side
effects Yusri also had a increase by 10 kg's. Now Yusri is in good health and continuously
administering Mas Ayu products.
CASE STUDY 6
A 54- year old male from the Drug Intervention Community (DIC) was detected of having
HIV Positive in 1990. He has a history of drug abuse since the age of 15. The period of
study begined on him in April 2007 until November 2007. Benjamin Ong Leong Wah was
first introduced to Alternative Medicine Research Institute- Asia in April 2007 by Mr.
Allen Tan, a member of Global Health Activism Network which is a network of trained
activist involved in the promotion of natural human healthcare and medicine. Mr. Allen
Tan convinced Mr. Benjamin to try our HIV/AIDS nutritional package for his medical
condition. He started taking SBCV products in April 2004. During that time Mr. Ong’s
disease had already progressed to AIDS despite of being treated with antiretroviral drug
since 1994. His general health was very poor, where he developed severe weight loss; he
was unable to move freely and was bed ridden most of the time due to the side effects of
anti-retroviral drug. In 1994 he was treated at the Kuala Lumpur General Hospital and later
his case was transferred to Sg. Buloh Hospital and later sent to Selayang General Hospital
where he underwent a major surgery to remove a tumor on his gall bladder. His surgery
went on successfully and he went through a rapid and remarkable recovery. The organ
damage in his body was mainly caused by the antiretroviral drugs which he was taking for
many years. He also developed tuberculosis and hepatitis C infection. He started on SBCV
HIV/AIDS regimen when the side effects of antiretroviral drug were destroying his
systems. This is because his lactate level reached high enough to cause his heart to fail.
Mr. Benjamin Ong Leong Wah
After the administration of SBCV product there was remarkable improvement in his health.
His appetite also improved and within two months of treatment, he gained 3 KG’s. After
about 4 months his lactate level became normal and he started on antiretroviral drugs again.
The most miraculous aspect of his recovery was the improvement in blood parameters
especially his liver function parameters, where his CD4 count and his viral load count was
reduced after the administration of Mas Ayu products. His CD4 count rose from below 300
to a staggering 857 in august 2007. His viral load which was more than 900,000 copies
during the peak of AIDS had become undetectable.
On the 23rd October 2007, the faxed copy of the report showed evidently that Mr. Ong has
become free from HIV/AIDS. The outcome from his review with infectious diseases
department of Sg. Buloh Hospital will be incorporated into this case study. Benjamin Ong’s
case is a classical case of how the devastating effects of antiviral drug was protected by
SBCV regimen and also allowed the CD4 count to reach an unprecedented level of above
LIVE TESTIMONY BY MR. BENJAMIN ONG
CASE STUDY 7
A 32-years old male named Norizam B. Jamal, who was a drug addict from the Pengasih
Centre, was detected of having HIV/AIDS due to needle sharing with other addicts in 2002.
Due to HIV/AIDS he developed a few opportunistic infections like tuberculosis,
pneumonia, lip ulcer, itchiness of the body, swelling at the neck and intermittent fever. He
has also complained of having dry skin, weakness, lethargy, dizziness and headache. He
was not under any antiretroviral drugs. This patient started Mas Ayu products in November
After the administration of SBCV product there was remarkable improvement in his health.
He was relieved from headaches and gained more energy and stamina. When patient was
visited on 28th February 2008 in Pengasih, he seems to be healthy and active even though
he was suffering from mild cough due to the weather. Patient also said that he developed
high fever (24 hour) in January 08 and recovered through PCM. He also claimed that he
could sleep well and feeling healthy these days. Blood test report showed mild
Normochromic Anemia but his CD4+ count increased tremendously after the
administration of highly active micro-nutrient wholesome formulae.
Progress of Patient CD4+
CD4+ COUNT Viral Load
July, 07 523 50
August, 07 516
January, 08 154 (Intervention) 288
18TH March 08 494
600 523 516
CD4+ 300 July, 07
200 154 Aug, 07
100 Jan, 08
0 Mar, 08
July, Aug, Jan, Mar,
07 07 08 08
CD4+ Count of Zainudin
CASE STUDY 8
A 68- year old male was confirmed HIV positive. HIV virus was detected in his blood
when a routine test was done when he volunteered to donate blood at the Kuala Lumpur
Blood bank in April 2004. The patient has no medical problems, his blood pressure and
blood glucose levels were all within normal limits. The HIV/AIDS clinic at Hospital Kuala
Lumpur did not prescribe any antiretroviral drugs. His CD4+ cell counts and general health
parameters were monitored periodically during his follow up visit to the HIV Clinic. He did
not show any clinical symptoms as it was still very early for the symptoms to show up.
Viral load studies were not carried out by the hospital. He decided to take naturopathic
treatment in 25th June 2007.
The CD4+ cell count recorded in this study was reported by the patient based on the reports
given by the HIV/AIDS clinic at Hospital Kuala Lumpur. His overall health was very good
without any infections in the four month period. No side effects were noted and patient did
not lose weight and his energy level and strength was much better with the treatment. No
skin allergy or lesions were noted. His overall health has been very good with high energy
levels and good strength and stamina. He has been taking the products daily without fail.
No infections or skin rashes was noted. There were absolutely no deleterious side effects as
expected because the products were all made from edible seeds and natural vitamins except
for Neem plus 250mg capsules which is a traditionally used Indian herb for viral
The patient was given the standard course of natural products developed at AK Pharmacy
and Naturopathy Center. The type and dosages is shown in the table below:
Natural Nutritional Treatment
SBCV* Products Morning Noon Night
Amirtha 250mg caps. 1 1 1
Semalu 250mg caps. 1 1 1
Neem 250mg caps. 1 1 1
Aki 250mg caps. 1 1 1
Tenang 250mg caps. 1 1 1
Kolostrum 250mg caps. 1 0 1
Goats Milk 1 0 0
Honey 1 0 0
In comparison with antiretroviral allopathic treatment, SBCV natural therapy is more
effective, safer for long term treatment and more affordable. This individualized study will
continue for 60 months to see the long term effects of this treatment on patients with HIV.
4.1 GENERAL CONCLUSIONS
Total nutritional formulas which can constantly optimize the body's physiological and bio-
chemical balance can reduce gradually. The viral replication and with time eliminate the
virus from the system. The SBCV creates a hostile environment for the virus in the blood
allowing the human immune response to be highly activated and offensive in nature,
possibly through the development of genetic HIV resistance through the suppression of
SBCV also protects the patients from the toxic side effect of HAART anti-retroviral drugs,
antibiotic and other potent drugs. SBCV package is the natural answer for both prevention
and treatment and even cure.
1) HIV Infection and AIDS
- Richard E. Chaisson M.D. and Thomas C. Quinn M.D.
2) Essentials of Anatomy and Physiology, 5th Edition
- McGraw – Hill International Edition, Seeley, Stephens, Tate, 2005, Library
Congress Cataloguing – in – Publication Data
- June 11th 2004.
4) V. Fuhrmans
- Cost of Long time HIV Drug Jumps, Reigniting Debate over Drug Pricing
Policies, Wall Street Journal, December 19th 2003.
5) AK Farmasi and Naturopathy Centre
18) Horowitz LG. Polio, hepatitis B and AIDS: an integrative theory on a possible
vaccine induced pandemic. Med Hypoth 2001;56(5):677-686.
19) Weiss, RA, Natural and iatrogenic factors in human immunodeficiency virus
transmission. Phil. Trans. R. Roc. Lond. B 2001;356,947-953.
20) Bliss M. Origin of AIDS (letter). The Lancet 2001;357 (January 6):73-74.
21) Marriott SJ, Lee TH, Slagle B and Butel JS. Activation of the HTLV-1 long
terminal repeat by the hepatitis B virus X protein. Virology 1996, 224;1:206-213.
Mr Ben Ong’s Medical Report from Selayang Hospital
27 June 2007
Mr Ben Ong’s Medical Report from Pathology Lab Kuala Lumpur Hospital October