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 roots for life
Fondation Mérieux’s mission
is to fight infectious diseases
affecting developing
countries by enhancing
local capacities.
It is an independent family foundation
with official charitable status.

      It has four main areas of action:
      Strengthening health infrastructures
      Training and sharing of knowledge
      Applied research
      Patient support
      With the support of Fondation Christophe
      et Rodolphe Mérieux, under the guidance
      of the Institut de France, it develops a network of training
      and applied research laboratories in the field,
      at the heart of developing countries.
Fondation Mérieux was created in 1967 by Dr. Charles Mérieux,
who named it in honor of his father, Marcel Mérieux, who worked
with Louis Pasteur and founded Institut Mérieux in 1897. It was
awarded official charitable status in France in 1976.
First and foremost, Fondation Mérieux is a great family undertaking in
which successive generations, sharing common values in the Pasteurian
tradition, have succeeded in passing on their vision of biology serving
public health worldwide.
By bringing together people with a wide variety of skills and cultural
origins, Dr. Charles Mérieux has succeeded in founding an exceptional
international network. Fondation Mérieux has thus played a unifying role,
acting as a catalyst of initiatives with the common goal of fighting
infectious diseases throughout the world.
Under Alain Mérieux and Dr. Christophe Mérieux, Fondation Mérieux has
refocused its action in the field, at the heart of infectious outbreaks.
Supported by Fondation Christophe and Rodolphe Mérieux, Fondation
Mérieux is today present in Mali, Cambodia, Laos, China, Haiti, Lebanon,
Madagascar as well as other countries.
In 2009, Fondation Mérieux and the Institut Pasteur signed an agreement
aimed at encouraging collaboration in the fight against infectious
diseases in developing countries, that includes research programs and
concrete actions in the field.

To ensure the effectiveness, sustainability and openness of its
actions, Fondation Mérieux operates under strict principles:
> Act impartially without regard for any commercial or industrial
> Give priority to projects that deliver tangible results
> Work with an international, multi-disciplinary team of scientific
experts, including doctors, pharmacists, biologists, researchers,
specialists in infectiology, vaccinology, epidemiology, and others
> Work in partnership with international development organizations
and health authorities, and local healthcare professionals, while
respecting each country’s practices and culture
> Ensure that its actions form part of a sustainable development
approach. In particular, Fondation Mérieux makes use of local skills
(builders, fitters, laboratory equipment suppliers) for all its projects
> Transfer the ownership of diagnostic and research tools set up
by Fondation Mérieux to local healthcare professionals and give
them the resources they need for effective long-term management of
the scientific and financial aspects.






                  Applied research
               LEBANON                             INDIA             LAOS




   BURKINA FASO                       MADAGASCAR                               CAMBODIA

          Permanent presence                             Programs
          of the Foundation experts                      and/or partnerships

     Training and sharing              Patient support                  Strengthening health
     of knowledge                                                       infrastructures
  diseases kill
     17 million                                          MÉRIEUX
  people each                                            IS ACTIVE
  year around                                            IN THE FIELD
   the world…                                            Projects serving four priorities
                   …developing countries account
for 16 million deaths, including 5 million children

                                                         Strengthening health
   4 children die of pneumonia                           infrastructures
                  every minute                           Fondation Mérieux makes cutting-edge scientific and
               the leading cause of death for children
                                                         medical tools available to developing countries
                                    under 5 years old
                                                         > Through its network of applied research and training
                                                         laboratories in developing countries, Rodolphe Mérieux
                                                         Laboratories, that are already set up in Cambodia, Laos,
                                                         Mali, Haiti and Madagascar, aim to become reference
                    Tuberculosis                         laboratories in their countries for applied research,
                    1.7 million deaths                   epidemiological surveillance and training.
                             each year                   > By refurbishing and equipping local healthcare
                                                         facilities: medical test laboratories in regional
                                                         hospitals and healthcare centers.
                                                         After identifying target facilities in the field, in Cambodia,
                                                         Laos, Madagascar, Haiti and India, Fondation Mérieux
                                                         has refurbished them and at the same time provided
                                                         training programs for healthcare staff.
                    2 million children
                        die each year
                  of which 90% are under 5 years old
                                                          20 million deaths in 20 years
                                                 <<       39.5 million seropositive people,
                                                          of which 2.3 million are children under 15 years old

                Training and
                     sharing                              Malaria
               of knowledge                               1 death every 30 seconds
                                                          500 million new cases each year
    Fondation Mérieux aims to play an active part         40% of the world population is exposed
          in the worldwide exchange and transfer
of scientific knowledge. Training and information
                   are at the heart of its strategy.

      Spreading scientific innovation                     Neglected tropical
       Fondation Mérieux aims to stimulate scientific
       reflection and promote innovation worldwide.       diseases
 It organizes numerous symposia and conferences
    in France and abroad, bringing together experts
                                                          1 person in 6 around
              to discuss current public health issues.    the world is affected
                 > The “Cent Gardes” symposium
                      on HIV, is held every two years ;
the last 2 were organized in Beijing and New Delhi.
               > The Christophe Mérieux “Trends
                            in Virology” conference       New emerging
            also held every two years, reviews recent
                 developments in infectious diseases
                    and particularly emerging viruses.    Since 1973, over  30 new diseases
  > Moving forward the diagnosis of infectious            associated with unknown viruses have appeared
                   diseases is an annual symposium
         on the issues in diagnosing key pathologies
                               in developing countries
     > Numerous conferences on more specific              WHO data

                 public health issues held in France
                          and in developing countries
                    Unequal access
                       to healthcare
                     15% of the world population benefits
             from 70% of worldwide healthcare expenditure

      The poorest countries only                                  Training healthcare professionals
  spend $16 per person per year                                   Fondation Mérieux organizes scientific and technical
                   on healthcare compared with an average         training for healthcare professionals in developing
                        of $2000 in industrialized countries      countries, including scientific experts, laboratory
                               and up to $4000 in the USA         personnel, medical students…
                                                                  Held in the field or at Les Pensières Conference Center,
                                                                  the training covers vaccinology, diagnosis,
                                                                  epidemiology or clinical biology laboratory
                                                                  management and techniques.
                                                                  > Promoting university education
                        A shortage                                Enhancing facilities for training the new scientific elites,
                                                                  such as opening the Faculty of Pharmacy of Phnom
                       of qualified                               Penh, Cambodia and assisting setting up
                   healthcare staff                               a new Faculty of Pharmacy in Madagascar.
                                                                  Advice on devising university programs for schools
                      Sub-Saharan Africa:                         of pharmacy and biology.
                         3% of worldwide                          > Training experts who pass on knowledge
                        healthcare staff –                         in the field
                                                                  ADVAC (Advanced Vaccinology Course) dedicated to
                          Americas: 42%                           at physicians involved in local, regional or international
                     57 countries, mostly in Africa and Asia,     decision makers (organized in partnership with the University
          suffer from a serious shortage of healthcare staff.
                                                                  of Geneva with the financial support from the European
         The worst-affected countries only have one doctor
                 for over 33,000 inhabitants compared with
                                                                  Commission and the Bill and Melinda Gates Foundation).
                   one doctor per 300 inhabitants in France.      > Enhancing know-how
                  Imbalance between towns and rural areas         Setting up local training actions to improve the professional
                                                                  know-how of clinical biology staff.
                                                                  - ACTION BIOMALI: improving clinical and biological
                                                                  diagnosis abilities in Mali through various training actions.
                                                                  - RESAOLAB: strengthening and building a network
                                                                  of laboratories in Mali, Senegal and Burkina Faso,
               Undiagnosed                                        continuous training of laboratory personnel, quality
                                                                  management and epidemiological monitoring (tuberculosis
               or incorrectly                                     and malaria). Program devised with the ministries of
                                                                  health in these three countries and financially backed
         diagnosed illnesses                                      by AFD (French Development Agency).
                              False negatives, false positives,
            unsuitable treatment, development of resistance
                              to treatments, contamination…
           Around 300,000 people in Senegal, Burkina Faso
           and Mali live with HIV, but 80% are unaware of it.
                                The majority of malaria cases
                              in Africa are poorly diagnosed.
One third of the world population is infected by tuberculosis,       GLOBE :
                                only 60% of                          new operational tool serving
                        cases are identified                         developing countries
                                                                     GLOBE (Global Link for Online Biomedical Expertise)
                                                     WHO data
                                                                     is a portal for scientific information and Internet-based
                                                                     e-learning. The portal aims to train and facilitate
                                                                     networking between scientists and healthcare
                                                                     professionals from developing and industrialized
                                                                     countries and provide operational solutions
                                                                     to questions that arise in their daily practice.
                                                                          Applied research
                       Fondation Mérieux is involved at various levels, supporting researchers in developing countries,
                                               and also directly conducting research programs in its own laboratories.

> Research programs on diseases such                            > Promote high level research
as tuberculosis, respiratory infections,                        in developing countries
malaria, HIV and hepatitis
                                                                Fondation Mérieux takes part in numerous local
Two applied research centers: the Laboratory
                                                                research programs on major pathologies (tuberculosis,
of Emerging Pathogens (Lyon-Gerland) and
                                                                HIV, malaria), providing expert advice, technical
the Christophe Mérieux Laboratory (created as part
                                                                resources and financial assistance.
of the Academy of Medical Sciences in Beijing).
Programs for the detection and identification                   Grants are awarded to young postgraduate
of emerging pathogens, including setting up tools               scientists from industrialized and developing countries
for epidemiological monitoring, locating biomarkers             and working on infectious diseases, in order to promote
of interest for studying infectious agents, creating            North/South exchanges and cooperation.
and transferring technologies suited to research
                                                                The Christophe Mérieux Prize is awarded each year
in developing countries.
                                                                by Fondation Christophe and Rodolphe Mérieux
> To conduct its applied research activities, Fondation         to researchers from developing countries who work
Mérieux has created an international network of research        in the field on infectious diseases.
laboratories, GABRIEL (Global Approach to Biological
Research on Infectious Epidemics in Low-income
countries). GABRIEL includes the various Rodolphe
Mérieux Laboratories around the world, as well as other
public or private international research units, hospital
laboratories, NGOs and corporations involved in diagnosis.
It is supported by two applied research centers: the
Laboratory of Emerging Pathogens (Lyon-Gerland) and
the Christophe Mérieux Laboratory (created as part of
the Academy of Medical Sciences in Beijing).
GABRIEL aim is to provide support to its members in
developing countries in their research projects on infectious
diseases through extensive exchanges of ideas, procedures,
data and experience in biosafety, biomathematics, bioethics,
project management and grant applications.
GABRIEL is conducting two major research programs
on tuberculosis and respiratory infections with the
objective to provide laboratory tools for the epidemiological
surveillance of infectious agents of pneumonia, influenza
and resistant tuberculosis based on technologies which
can also be applied to other diseases like malaria, HIV,
diarrhoea or hepatitis.
Although Fondation Mérieux’s field
of expertise is biology, it also aims
to take a more general approach
to public health by developing actions
to support patients and accompany them
in their return to active life.
> Microcredit program:
This program, conducted in Haiti,
in partnership with ACME (Association
for Cooperation with Micro-Enterprises) and
with the support of the GHESKIO Centers,
entitles seropositive women to a range of
services including medical diagnosis,
healthcare and monitoring, information,
training and access to microcredit.
> Programs to improve screening
and monitoring of infectious diseases
(HIV, tuberculosis, malaria, etc.) in
underprivileged regions (ACTION BIOMALI
throughout Mali, screening for Chagas’ disease
in Argentina, etc.)
> Subsidies for humanitarian initiatives
conducted by local NGOs in the field, aimed
at assisting people in developing countries and
facilitating access to healthcare.
                                                  Our supporters
                          Fondation Mérieux benefits from the financial support
of its long-term partners, including healthcare corporations, large foundations,
             the European Community and international development agencies.
           Through their confidence and their commitment, Fondation Mérieux
       is able to undertake long-term actions and adopt a sustainable strategy
                   in the fight against infectious diseases throughout the world.
                  69002 Lyon / France

               Fax: 33 (0)4 72 40 79 50
               Tel: 33 (0)4 72 40 79 79
                     17, rue Bourgelat
07-09 - Printed in France on recycled paper - Credit photo : J. Millet, Jupiterimages, C. Ganet, studio Bergoend, J.B. Mercier & studio K, P. Tournaire, C. Bécam, B. Eymann - THERA Conseil - RCS Lyon B 396 160 242

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