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					LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE
(University of London)

DEPARTMENT OF INFECTIOUS AND TROPICAL DISEASES

DISEASE CONTROL AND VECTOR BIOLOGY UNIT

ADMINISTRATOR, MENINGOCOCCAL CARRIAGE CONSORTIUM

FURTHER PARTICULARS

1. ADVERT

A challenging opportunity is available for an experienced project administrator who will
support a large multicentre study of meningococcal carriage before and after the
introduction of a new meningococcal conjugate vaccine, developed by the Meningitis
Vaccine Project, into countries of the African meningitis belt. The study, which is being
supported by the Bill and Melinda Gates Foundation and the Wellcome Trust, will be
conducted in seven African countries and will last three years.

Responsibilities of the consortium administrator, who will be based in London, will
include supporting the seven African sites participating in the trial, managing the
consortium budget, developing the consortium website, providing assistance with the
purchase of supplies and organisation of consortium meetings in Africa and elsewhere.

Applicants should have proven experience of programme management, excellent IT and
organisational skills and be highly motivated. Experience of/or interest in developing
countries, especially those in Africa would be desirable.

An appointment will be made as soon as possible. A contract of 36 months will be
offered on the Professional Support Pathway Scale grade 5 from £30,639 - £35,194. The
successful candidate will be placed on the appropriate scale point according to skills and
experience.

For further particulars and an application form please contact the Personnel Office,
LSHTM (email: personnel@lshtm.ac.uk, Fax: 0207 636 4771, tel: +44 20 7927 2203 (24
hour answerphone)). The closing date for the receipt of applications is Friday 12 June
2009. Please quote reference BG-Mencar-2.

  “The London School of Hygiene & Tropical Medicine is committed to being an equal
                              opportunities employer”
2.     GENERAL INFORMATION

The London School of Hygiene & Tropical Medicine

The London School of Hygiene & Tropical Medicine has an internationally recognised
reputation in public health and tropical medicine, is a leading postgraduate medical
Institution in Europe and is Britain’s national school of public health. A special strength
of the School’s research is its multi-disciplinary nature: leading researchers have
backgrounds in public health medicine, epidemiology, clinical medicine, infectious
diseases, chemotherapy, biochemistry, immunology, genetics, molecular biology,
entomology, statistics, demography, health economics, public health engineering,
medical anthropology, health promotion, environmental health management, and health
policy.

The mission of the London School of Hygiene & Tropical Medicine is to contribute to the
improvement of health world-wide through the pursuit of excellence in research,
postgraduate teaching and advanced training in national and international public health
and tropical medicine, and through informing policy and practice in these areas.

Department of Infectious and Tropical Diseases

The Department of Infectious and Tropical Diseases encompasses all of the laboratory-
based research in the School as well as that on the clinical and epidemiological aspects
of infectious and tropical diseases. It is headed by Simon Croft, who is Professor of
Parasitology. The range of disciplines represented in the department is very broad and
inter-disciplinary research is a feature of much of its activity. The spectrum of diseases
studied is wide and there are major research groups with a focus on malaria,
tuberculosis, HIV/AIDS and other sexually transmitted diseases, vaccine development
and evaluation, and vector biology and disease control. The Department is organised
into four large research units comprising: Pathogen Molecular Biology, Immunology,
Disease Control and Vector Biology, and Clinical Research. There is close interaction
between scientists in different research teams. The Department has strong overseas
links, which provide a basis for field studies and international collaborations in developed
and developing countries. The teaching programme includes MSc courses, taught in-
house and by distance learning, which are modular in structure, a variety of short-
courses and an active doctoral programme (PhD and DrPH).

Disease Control and Vector Biology Unit

This multidisciplinary Unit, headed by Dr. Nigel Hill, includes epidemiologists,
entomologists, anthropologists, social scientists, clinical scientists, public health
engineers, and geographers. This range of expertise provides a battery of tools for
focusing on the control of diseases that are insect-borne, water-borne or associated with
poor social and living conditions including acute respiratory infections and meningitis.
Much of the research can be categorised as: evaluating disease control interventions;
investigating implementation strategies - including working with the private sector;
understanding the factors underlying household behaviour in relation to family health; or
determining how control resources can be targeted most efficiently. Particular attention
is paid to research directed at current health policy issues, including the gap between
policy and practice. The DFID Resource Centre for Water and Environmental Health
(WELL) and the Hygiene Centre make up the Unit's Environmental Health Group, which
plays a leadership role in research and operational support for hygiene promotion, water
supply and sanitation. The Unit also houses the largest research group in LSHTM
working on malaria control, including the DIFD Team for Applied Research to Generate
Effective Tools and Strategies for communicable disease control (TARGETs) and the
new Malaria Capacity Development Consortium (MCDC). The Unit’s valuable mosquito
colonies are used for testing repellent products and insecticides in the laboratory. The
Unit also includes a major grouping of researchers using spatial analysis in public health.

Teaching

The School offers 22, one year full-time taught courses leading to the Master of Science
(MSc) degree of the University of London and the Diploma of the London School of
Hygiene and Tropical Medicine (DLSHTM). The Department of Infectious and Tropical
Diseases runs or contributes substantially to ten of these courses and the “Immunology
of Infectious Diseases” course is run from within the Immunology Unit. In addition, the
Department is responsible for the three-month Diploma in Tropical Medicine and
Hygiene (DTM&H) and offers a range of specialist short courses usually lasting one or
two weeks. Three MSc courses are also offered by Distance-based Learning, including
one on Infectious Diseases.

Research Training

The School offers two doctoral training programmes. The MPhil/PhD degrees are
designed for those who wish to go on to a full time research career. The DrPH is
directed towards those who expect their careers to be more in the practice of public
health.

Project information

For over 100 years, major epidemic of meningococcal disease have occurred across the
Sahel and sub-Sahel regions of Africa – the African meningitis belt. These epidemics
can involve tens of thousands of patients and cause many deaths. For the past 30 years,
control of epidemics has depended upon the early detection of outbreaks and reactive
vaccination with polysaccharide vaccines. This approach has saved many lives but has
not prevented epidemics which continue to occur on a regular basis as polysaccharide
vaccines do not induce lasting immunity. This situation has been changed by the
development of conjugate vaccines which are immunogenic in young children and which
induce immunological memory.

A new serogroup A meningococcal conjugate is being developed for use in Africa by the
Meningitis Vaccine Project (MVP), a public private partnership supported by the Bill and
Melinda Gates Foundation. This vaccine, which is being produced by the Serum Institute
in India, is currently undergoing phase 2 clinical trials in several countries in Africa.
Immunogenicity and safety results from these trials are very encouraging and it is
anticipated that the vaccine will be deployed in Burkina Faso in 2009/2010 with other
meningitis belt countries following shortly afterwards.

If the new vaccine is to be successful, it must be able to prevent pharyngeal carriage of
meningococci and thus interrupt transmission. Little is known about the pattern of
pharyngeal carriage in Africa and much of the information that is available comes from
studies done many years ago. Thus, it is proposed to undertake a series of carriage
studies across Africa to define the age pattern of carriage, its duration and rates of
acquisition. These field studies will be accompanied by detailed molecular
characterization of the carriage isolates. The studies will help to define the age group of
subjects who need to be vaccinated in the mass vaccination campaigns that will take
place once the new vaccine has been licensed. Studies will be repeated in two or three
countries after vaccination has been introduced to ensure that the new vaccine does
prevent carriage.

This large programme of work will be undertaken by a consortium that includes seven
partners in Africa, eight partners in Europe, the Centers for Disease Control, Atlanta,
WHO and the Meningitis Vaccine Project.

Further information about this project can be obtained from Professor Brian Greenwood
(brian.greenwood@lshtm.ac.uk) or Dr Amit Bhasin (amit.bhasin@lshtm.ac.uk) at LSHTM.



4. JOB DESCRIPTION

Post:                   Administrator, Meningococcal Carriage Consortium

Grade:                  PSP 5

Responsible to:         Dr Amit Bhasin

Unit:                   Disease Control & Vector Biology

Start date:             1st July 2009

The post holder will have overall responsibility for providing administrative and
managerial support to the consortium’s research studies that will be undertaken at seven
field centres. They will take responsibility for the day to day administration of the
consortium, assisting in the procurement of supplies for field centres, contract
administration (including the monitoring of expenditure reports from centres), managing
consultants employed by the consortium and preparing financial reports for funders.

The administrator will work with other member of the consortium: a project leader, a
serology coordinator and a data manager.

Specific responsibilities will include -

Strategy and Communication

        to assist the consortium Director and other staff in liaising with and forming new
         collaborative links with staff from organizations and institutions with involvement
         in meningococcal vaccine research, both in the UK and abroad

        to establish an informative website which will form the basis of the establishment
         of a strong network of consortium members and which will disseminate the
         activities of the Consortium to the wider scientific and non-scientific community

        to assist the Director in the development and implementation of a
         communications strategy

        to co-ordinate the production of publicity material for the Consortium on its
         various activities and to prepare contributions for LSHTM Annual reports

        to assist the Director in preparing reports and reviews of the consortium’s
         activities as required by funders and other bodies
Financial Management

     to liaise with the LSHTM Contracts Officer to establish and/or amend research
      collaboration agreements as necessary

     to manage the consortium’s UK budget including the preparation of projections
      and producing summaries of the consortium finances on a regular or ad hoc
      basis and, if required, to present these to partners

     to assist the nine partner institutions receiving funds from the consortium to
      establish working budgets for each of the three potential co-funders and to
      develop a mechanism to regularly monitor expenditure from these budgets in line
      with funder requirements

     to establish consultancy agreements, including monitoring all contractual and
      financial arrangements arising from these

     to assist the consortium Director in the submission of annual financial reports to
      each of the funders

     to liaise, as necessary, with programme staff at the funding organisations


Administration

     to act as the first point of contact for consortium members from the UK, Africa,
      Europe and the USA

     to main maintain excellent working relationships with national and international
      collaborators

     to provide logistical support to the African partners, including sourcing and
      shipping equipment and supplies as necessary

     to organize the annual consortium meeting, including selection of an appropriate
      venue (which may be overseas) and all necessary travel and accommodation
      arrangements

     to provide support to the consortium steering committee by servicing meetings as
      required, including coordinating the production and distribution of agendas,
      reports and presentations

     to provide support to consortium members in organising and arranging travel,
      visas and reimbursement of expenses

     to provide administrative support to the scholarship programme that will allow
      students selected by the consortium to complete Distance Learning MSc’s at
      LSHTM

     to travel on site visits as required
Personnel Administration

      in conjunction with the Director and the Personnel Officer, to be responsible for
       all administrative matters relating to consortium staffing, including recruitment,
       monitoring probationary periods, extensions of contract, appraisals, staff
       development and training, ensuring that School procedures are adhered to

      to ensure that new consortium staff receive appropriate induction to the
       consortium and its operation and are provided with all necessary information

      to monitor and report as necessary on all staff sickness absence


Other Duties

      to respond to requests from the Unit and Departmental Administrator on all
       matters relating to unit and departmental administration

      to undertake other reasonable duties as may be required by the Director or line-
       manager.


5. PERSON SPECIFICATION

Essential and Desirable qualifications and skills for this post are as follows. It is
recognized that candidates may not fulfil all of the desirable requirements.


Essential requirements


      proven successful experience in the administration of scientific projects or
       programmes in a relevant area
      proven successful experience in preparing and monitoring complex budgets and
       preparing financial forecasts

      excellent written and oral communications skills including a high level of accuracy
       and a proven ability to write reports to a high standard

      a proven ability to work on own initiative, including an ability to know when to
       confer with colleagues and/or refer matters on

      excellent organisational skills including a proven ability to manage a significant
       workload under pressure and to organise and prioritise effectively

      excellent IT skills including the use of word processing packages, databases and
       an advanced working knowledge of spreadsheets

      excellent interpersonal skills, including a proven ability to establish and maintain
       effective working relationships with individuals from different backgrounds and
       cultures
Desirable requirements

         proven experience of organising and servicing meetings and workshops

         proven experience of designing and maintaining web-pages and a good working
          knowledge of Dreamweaver or other web development applications

       a working knowledge of French

         a willingness to periodically undertake site visits and other UK or non-UK work
          related travel

         experience of/or interest in developing countries, especially those in Africa




7.        SALARY AND CONDITIONS OF APPOINTMENT

The post is funded by grants to LSHTM from The Bill & Melinda Gates Foundation and
the Wellcome Trust for a period of 3 years and is available from 01/07/09. Salary is on
the Professional Support Pathway Grade 5 scale from £30,639 - £35,194 (inclusive of
London Weighting). Annual leave entitlement is 30 working days per year for all staff
(pro-rata for part-time staff). In addition to this there are 6 fixed-date "Director's Days".


8.        APPLICATIONS

Applications should consist of a letter of application addressing the requirements in the
Person Specification, plus a typed curriculum vitae with a daytime telephone number
and the names, email contacts, addresses and telephone numbers of two professional
referees who may be approached immediately, one of whom should be a recent
employer or academic supervisor.

Applications, quoting the appropriate reference number should be sent to the Personnel
Office, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E
7HT (email: personnel@lshtm.ac.uk fax: 0207 636 4771). Closing date for the receipt of
applications is Friday 12 June 2009. Please quote reference BG–Mencar–2. If you do
not hear from the Personnel Office by 10 July 2009 you should assume that your
application has not been shortlisted.

     “The London School of Hygiene & Tropical Medicine is committed to being an equal
                                 opportunities employer”

				
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