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					                                                  Anesthesia Technician Pharmacology
                                                                                                 50 kg
   Category            Generic           Trade         Form                  Dose                100kg
                                                                                                                     Reversal        Indication              Contra                        Notes

Benzodiazepines
                                                   Injection                                                                                         Narrow angle
                  Diazepam             Valium      5 mg/ml             5-10 mg                                    Flumazenil         Pre-op sedation glacoma                    Max dose 30 mg
                                                   Injection 1                              100 kg:                                                                             Intolerence to Benz.
                                                                       50 kg:
                  Midazolam            Versed      5 mg/ml                                  0.07 = 7 ml           Flumazenil         Pre-op sedation                            Max 2-5 mg
                                                                       0.07 = 3.5 ml
                                                                       0.08 = 4 ml          0.08 = 8 ml
Induction
                                                                                            50 kg: 0.2 mg = 5 ml                     General                                    Immunosuppressed
                  Etomidate            Amidate     2 mg/ml             0.2-0.3 mg/kg        100 kg: 0.2 mg = 10 ml                   anesthesia                                 patient
                                                                                            50 kg: 2 mg = 10 ml                      Induction and
                  Propofol             Diprivan    10 mg/ml            1-2.5 mg/kg          100 kg: 2 mg = 20 ml                     maintenance


Analgesia
                                                                                            50 kg: 1-2 ml         Naloxon 0.2-0.4    Analgesia &        Pregnancy-crosses
                  Fentanyl             Sublimaze   50 mcg/ml           1-2 mcg/ml           100 kg: 2-4 ml        mg IV              Anesthesia         placenta barrier,
                                                                                                                                                        Depression occurs
                                                                                                                                                        w/prolonged exp. to
                                                                                                                                                        transdermal patch
                                                                       Adult: 2.5-5 mg      50 kg: 25-150 ml      Naloxone,          Analgesia &        Pregnancy-crosses       May reduce effects of diuretics;
                  Morphine Sulfate     Morphine    50 mcg/ml           Child: 0.05-0.2mg/kg 100 kg: 50-300 ml     Naltrexone         Anesthesia         placenta barrier,       Be careful not to confuse the
                                                                                                                                                        Neonates may need       highly concentrated oral solution
                                                                                                                                                        resuscitation so have   (100 mg/ml) w/the solution for
                                                                                                                                                        Naloxone                injection
                                                   1 mg powder 3 ml    Main: 0.05 to 0.8    50 kg: 0.0002 mg =0.03 ml                                   Continuously            Onset 1 to 5 mins.
                  Remifentanil         Ultiva      vial, 2 mg powder   mcg/kg/min, Post -op 100 kg: 0.0002 mg = 0.06 ml                                 monitor oxygen          Rarely used for induction
                                                   5 ml vial, 5 mg     pain: 0.025 to 0.2
                                                   powder 10 ml vial   mcg/kg/min

                                                                       Induction: IV 2 to 10 50 kg: 0.03 mcg =0.03 ml
                  Sufentanil Citrate   Sufenta     50 mcg/ml           mcg     Infusion: 0.01 100 kg: 0.03 mcg= 0.06 ml
                                                                       to 0.05 mcg/kg/min

Neuromuscular                                                                               50 kg: 1 mg = 50 mg   Neostigmine with   For anesthesia
Blockers          Rocuronium           Zemuron     10 mg/ml            0.6-1 mg/kg          100 kg:1 mg=100 mg    glycopyrrolate     induction
                                                                                            50 kg: 0.1 mg=5 mg  Neo w/ glyco         For anesthesia
                  Vecuronium           Norcuron    10 mg/ml            0.05-0.2 mg/kg       100 kg:0.1 mg=10 mg 0.01 mg/kg           induction
                                                                                            50 kg: 0.1 mg=5 mg  Glycopyrolate 0.2    For anesthesia
                  Pancuronium          Pavulon     2 mg/ml             0.04-0.1 mg/kg       100 kg:0.1 mg=10 mg mg/dose given        induction
                                                                                            50 kg: 1 mg = 50 mg                                                                 Onset: Immediate
                  Succinylcholine      Anectine    20 mg/ml            1-1.5 mg/kg          100 kg:1 mg=100 mg                                                                  MH susceptible

Maintenance
                                                                       Titrate to offset,                                            Pediatric          Overt renal disease,
                  Sevoflurane          Ultane      Volatile liquid minding other                                  Stop flow, time                       MH susceptible
                                                                                                                                     patients
                                                                       drugs on board,                                                                  Hypotension, MH         Crosses placental barrier,
                                                                                                                                     general            susceptible             tachycardia, glucose elevation
                  Isoflurane           Forane      100 ml              tolerance, etc…                            Stop flow, time
                                                                                                                                     anesthesia
                                                                                                                                                         Hypotension, MH
                  Desflurane           Suprane     100 ml                                                         Stop flow, time                        susceptible
                                                                                                                                      Notes for all three: Apnea, resp. depression, arrhythmia, increased cranial
                                                                                                                                                                                                        pressure

                                                                         Prepared by AT Class 2011-12                                                                                                      Page 1
                                                                                                 50 kg
   Category            Generic          Trade            Form                  Dose              100kg
                                                                                                                    Reversal             Indication               Contra                          Notes

Reversal                                                                                    50 kg               100 kg
                                                                                                                                        Non depolarizing                          Dosage with glyco is less than
                   Neostigmine        Prostigmin 1 mg/ml                 0.01 mg/kg         0.01 mg/0.5 ml      0.01 mg/1 ml            muscle relaxants     Bradycardia & asthma by itself
                                                                                                                                        Reversal for
                   Flumazenil         Romazicon 0.1 mg/ml                4-20 mcg/kg        10 mcg/5 ml         10 mcg/10 ml            benzodiazepines                               Titrate 3 mg/hr max
                                                                                                                                        Reversal for                                  Titrate 1 mg max
                   Naloxone           Narcan        0.4 mg/ml            0.1-0.2 mg         0.2 mg/25 ml        0.2 mg/50 ml                                 Cardiac disease          5-10 mcg/kg children
                                                                                                                                        narcotics -
Anti-emetics                                                                                                                            Causes pain
                                                    2 ml, 10 ml vials                                                                   Treat gastric    Don't use for patients Don't use in non high risk,
                   Ranitidine         Zantac        25 mg/ml             50 mg 2x daily                         N/A                     ulcers,          with hypersensitivity aspiration in surgical patient
                                                                                                                                        gastroesophageal to ranitidine
                                                                                                                                        reflux
                                                                                                                                                                                      For perioperative nausea and
                   Ondansetron HCL    Zofran        4 mg = 2 ml          2 to 4 mg                              N/A                                                                   vomiting

Diuretics
                                                    Injection and                                                                        Protection of renal
                   Mannitol           Osmitrol                           15%-20% solution                       N/A                      function during
                                                    irrigation
                                                                                                    Note: Also reduction of intracranial periods of          Contraindicated in patients with pulmonary edema,
                                                                                                       pressure & intraocular pressure hypoperfusion;        congestive heart failure, severe dehydration, impaired
                                                                                                                                         TURP irrigation     renal function, edema associated w/capillary fragility or
                                                                                                                                                             acute intracranial bleeding
                                                    Injection, tablets   For bolus do not                                               Hypertension;        Contraindicated in anuria & pregnancy. Use caution in
                   Furosemide         Lasix         and oral solution    exceed 1g/day                          N/A                     pulmonary &          patients w/severe or progressive renal & hepatic disease and
                                                                                                                                        cerebral edema;      those allergic to sulfonamides and those with severe
                                                                                                                                        edema of cardiac;    electrolyte imbalances
                                                                                                                                        hepatic or renal
                                                                                                                                        origin

Locals
                                                    0.25%, 0.5%,         EPI 50-100 mg,
                                      Marcaine
                                                    0.75 %, 10 ml        0.25%-0.75%
                   Bupivocaine HCL    Sensorcaine
                                                    plastic ampules
                                      Marcaine                                              Do not exceed 400 mg in 24 hrs
                   Heavy Bupivocaine Sensorcaine    0.5% / 1/2%          5mg/ml             (max single dose is 175 mg)                                                                                 Spinal
                   plus
                   Dextrose/Glucose
                                                                      Infiltraton peripheral nerveblock
                   Prilocaine HCL     Citanest       0.5%-2% solution 0.5-0.6 mg/kg                                                                                                     Regional Anesthesia
                                                                      Max dose: 6mg/kg without epi
                                                                      9mg/kg with epi 1:200,000
                                                    1.5% and 2%       Max 200-300 mg/hr        Dose: With epinephrine (other than
   Xylocaine Jelly, Lidocaine HCL     Xylocaine     solutions         Max dose: 4.5 mg/kg spinal) max dose is 500 mg (7mg/kg)

 Xylocaine viscous
      oral solution




                                                                           Prepared by AT Class 2011-12                                                                                                            Page 2
                                                                                                50 kg
   Category        Generic           Trade          Form                  Dose                                   Reversal           Indication                Contra                        Notes
                                                                                                100kg
Others
                                                                                          Max dose: 40        CPR, asystole, symptomatic bradycardia     Avoid when tachycardia would be harmful. Avoid in
              Atropine Sulfate                 Injection                                  mcg/kg, event                                                  hyperpyrexial states because it inhibits sweating.
                                               Injection           1 ml ephedrine to 9 mg saline=10 ml                                                   Used for spinals and epidurals; use caution in patients
                                                                                                                                    Hypotension and
                                               30 mg/10 ml =       syringe                                                                               with hyper tension and ischemic heart disease
              Ephedrine Sulfate                3mg/ml                                                         N/A                   bradycardia

                                                                   Cardiac arrest: 0.5 - 1 mg IV bolus                              Inotropic support;   Be cautious with       May be administered through
                                                                   every 5 min; inotropic support: 2 - 20 N/A                       anaphylaxis;         coronary artery        the endotracheal tube
              Epinephrine HCL     Adrenaline Chloride                                                                               cardiac arrest;      disease, hypertension,
                                                                   mcg/min (0.1 to 1 mcg/kg/min);
                                                                                                                                    increases local      diabetes mellitus
                                                                   anaphylaxis: 100 - 300 mcg IV push,                              anesthesia
                                                                   depending on severity
                                               Injection
              Glycopyrrolate      Robinul      0.2 mg/ml                                  0.2 mg for every 1 mg of neostigmine                           Avoid when tachycardia would be harmful
                                               Injection                                                                                                 Long-term therapy for bronchial asthma; reversal for
              Aminophylline       Theodur      25 mg/ml             IV 5 to 6 mg/kg                           N/A                                        bronchospasm
                                  Humulin R,   5 to 10 units in adults; 2 to 4 units in                                             Indication: Diabetic ketoacidosis,         10 to 15 minutes before meals
              Insulin             Novolin R    children                                   N/A                 N/A                   treatment of diabetes mellitus,            and at bedtime
                                                                                                                                    hyperkalemia




                                                                      Prepared by AT Class 2011-12                                                                                                          Page 3

				
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