NEOPLASMS IN FISHES
●Tumor originated from liver, epidermis, hem
tissue, connective tissue, pigment cells, per
● Liver cancer--chemical etiology, viruses
EPIZOOTICS LIVER NEOPLASM
● Found in 12 fishes lived in heavy polluted water
1. Fish treated with carcinogen produced liver
2. Fish liver indirect acting to carcinogen.
3. Extract polluted water produced skin cancer.
3. Extract Hamilton Harbor induced liver cancers.
5. Transfer toxins
6. No EM evidence of viruses
EPIZOOTICS EPIDERMAL NEOPLASMS
● Viral (plaque type) and chemical (smooth lobular
● Plaque, fish pox, multiple, low, white opaqe
lesion scattered over skin.
● Hervesvirus was isolated fron skin, grown in
FHM (fathead minnow), EPC (epithelioma
● Globular epithelioma lip and mouth from
EPIZOOTICS HEMATOPOIETICS NEOPLASMS
● Tumor from skin-muscle-kidney, spleen, livers.
Tumor large unidentified blast cells
● No viral etiology
● Diseased fish, exophthalmia,petechiae, ascites,
splenomegaly, transmiable by intraperitoneal
EPIZOOTICS CUTANEOUS FIBRIOCYTICS
● Occurred in marine, in dermis, ossifying fibroma.
Tumor of trunk, stratum compactum, ori from
dermal fibrous tissue.
● No chemical etiology
EPIZZOTICS PIGMENT CELL NEOPLASM
● Due to genetics, chemical, age, “chromato-
blastomas”. Prevalence 0-47 %, highest in kraft
● Tumor exhibit production pigment, prevalency up
to 50 %.
EPIZOOTICS PERIPHERAL NERVE
● Schwannomas & neurofibromas in wild fish.
Occurs in fin, skin, pigmented. Transmitable by
injection (84 %).
Liver cancers indicate the carcinogen, fish pox viral
origin, squamous chemical origin