ProKnee Bplan ppt

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					  Ravi Chacko CEO
Chase McCaleb CFO
 Walker Plash CMO
     Perry Yin CTO
  George Zhou CRO
           Problem | Market | Company | Product| Business Plan | Development| Finances



   ACL Injury
 100,000 -200,000 rupturs per year1
 60,000-75,000 ACL reconstructions
  are performed annually2
 Surgery > $10,000; Rehab >$10,000;
  Time ~ 1 year 3
 Lifelong effects (i.e. Patellofemoral
  Syndrome, Osteoarthritis)
 No currently available options for
  general risk assessment aimed
  towards prevention



  1. Mayo Clinic Online
  2. JD Hubbell, MD; E Schwartz, MD; http://emedicine.medscape.com/article/89442-overview
  3. WebMD
      Problem | Market | Company | Product| Business Plan | Development| Finances




Market
 CDC estimates 7.2mil high school athletes in the US1
 NCAA comprises 400,000+ athletes
    700+ men’s and 500+ women’s soccer teams total
 FIFA estimates 265mil people play soccer worldwide2
    In soccer, 70% of all ACL injuries are non-contact3
    UEFA’s top 25 teams have an operating income of over $1
     billion and revenue of $7 billion in 20094


 1. CDC: MMWR; September 29, 2006 / 55(38);1037-1040; http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5538a1.htm
 2. A Junge; J Dvorak; Br J Sports Med 2007 41: i3-i7; doi: 10.1136/bjsm.2007.036020
 3. Katharina Grimm, MD; Holly Silver, PT; Bert Mandelbaum, MD; Health and Fitness for the Female Football Player ;
    http://www.fifa.com/mm/document/afdeveloping/medical/ffb_gesamt_e_20035.pdf
 4. http://www.forbes.com/lists/2009/34/soccer-values-09_Soccer-Team-Valuations_Rank.html
        Problem | Market | Company | Product| Business Plan | Development| Finances




          The ProKnee Advantage

Mechanical and
Mechanical or             Laboratory
                           Wearable                Small scale data
                                                       Massive
                                                      Massive
 Physiological
Physiological               based
                         during athletic                                       ProKnee
                                                     collection
                                                      database
                                                      database
  Modeling
  Modeling                movements
                          movements
 Problem | Market | Company | Product| Business Plan | Development| Finances




Design
     Problem | Market | Company | Product| Business Plan | Development| Finances




 Design – Insole Attachment
 Gyroscope/Accelerometer
   • Work together to give position to calculate ankle angle
 Wire
   • Connects to knee straps for power and to relay data
 Force Sensors
   • Force summed to find moment at knee at impact
   • Determines time
   of impact
     Problem | Market | Company | Product| Business Plan | Development| Finances




 Design – Knee Straps
 Gyroscope/Accelerometer
   • Work together to give
     position to calculate flexion
     angle and medial motion
     angle
 EMG (VL-ST)
   • Measures muscle activation
 Wire
   • Connects to hip pack for
     power electronics and relay
     data
     Problem | Market | Company | Product| Business Plan | Development| Finances




 Design – Hip Pack
 Battery (9V)
   • Power electronics in unit
 USB Memory (1 GB)
   • Stores data for use with
     software later
 Gyroscope/Accelerometer
   • Work together to give
     position and angle of torso
 Wire
   • Connects to knee straps to
     power electronics and
     receive information
 Problem | Market | Company | Product| Business Plan | Development| Finances




Design
    Problem | Market | Company | Product| Business Plan | Development| Finances




Business Model
            Phase 1:                                      Phase 2:
          Prototyping                         Research and Development
• Proof of concept                          • Distribute to select athletic
• Initial working prototype                   teams and collect data
  and testing                               • Proof of concept: able to
• Fundraising                                 identify individuals at risk
  • Venture Capitalists                       • build consumer
  • SBIR                                        confidence in our product
                                            • Strategic Partnerships
                                              • Researchers
                                              • Military
                                              • Sports teams and industry
  Problem | Market | Company | Product| Business Plan | Development| Finances




Business Model (cont.)
      Problem | Market | Company | Product| Business Plan | Development| Finances




        Phase I         Phase II          Phase III              Phase IV
Months: 0           6                18                 30
   Phase I
    Prototype 1 – Accurately model knee movement:
     Test 1: Differentiate between people
     Test 2: Differentiate between motions of an
     individual
   Prototype 2 – Portable enough for athletic use
     Maintain accuracy and repeatability
    Display movements and muscle firing in a
   computer model
      Problem | Market | Company | Product| Business Plan | Development| Finances




        Phase I         Phase II          Phase III              Phase IV
Months: 0           6                18                 30
   Phase II
    Apply for FDA approval and patent
    License to industry and academia
    Clinical Trials 1 (Predictive)
   Phase III
    Clinical Trials 2 (Preventative)
    Market to sports teams
    1st generation release
   Phase IV
    Review data for 2nd generation release
        Problem | Market | Company | Product| Business Plan | Development| Finances




Phase I Budget
Part and ID#                             Notes                                          Source        Quantity Unit Price Subtotal
MEMS Gyroscope (497-8971-1-ND)           DUAL AXIS 16-LGA ±300°/s                       Digikey               9       8.74    78.66
MEMS Gyroscope (ADXRS612BBGZ-RLCT-ND)    IC SENSOR GYRO 7MV 250D/S 32CBGA               Digikey               3     31.74     95.22
MEMS Accelerometer (497-8327-1-ND)       ±2g, 8g; 3-axis; Analog Out                    Digikey               1     13.63     13.63
MEMS Accelerometer (551-1063-1-ND)       ±2g, 8g; 3-axis; Analog Out; Shock Resistant   Digikey               3     16.41     49.23

Wii Motion Plus (Gyroscope Attachment)   Keith's Suggestion                             Nintendo             2           17.96    35.92
Wiimote                                  1 borrowed, 1 purchased                                             1           40.00    40.00

Knee brace                               Borrowed                                       Amazon.com           1           15.00    15.00
Arduino microcontroller                  Borrowed                                       Arduino              2            0.00     0.00

EMG Amplifier                            Lafayette 70702 EMG Amplifier                  GetThatPart          1           49.00    49.00
Oscilloscope                             Borrowed                                                            1            0.00     0.00

NIDAQ USB                                Multiple inputs, so A/D converters needed      Borrowed      2-3                 0.00     0.00
Computer with MATLAB software                                                           Borrowed      1                   0.00     0.00
Batteries                                                                                             10                  1.00    10.00
Large EKG/EMG contact pads                                                                            10                  2.00    20.00
ECG electrodes                                                                                        2                   0.25     0.50

                                                                                                                 Total           407.16
             Problem | Market | Company | Product| Business Plan | Development| Finances




         Financial Projections
             Phase I       Phase II          Phase III              Phase IV
$3,500,000

$3,000,000

$2,500,000

$2,000,000
                                                                                       Revenue
$1,500,000                                                                             Expenditures
                                                                                       Running Net
$1,000,000

 $500,000

       $0
             0        6        12        18       24        30        36        42
                                        Time (months)
Thank you
 Dr. Paul Sadja
    Associate Professor of Biomedical Engineering
 Jim Gossett
    Associate Athletics Director for Sports Medicine
 Paige Plash
    Physical Therapist, COO Encore Rehabilitation
 Dr. Elizabeth Hillman
    Assistant Professor of Biomedical Engineering
 Keith Yeager
    Senior Staff Associate, Laboratory Manager
Questions?

				
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posted:8/8/2012
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