UNIVERSITY OF CAMBRIDGE SCHOOL OF CLINICAL MEDICINE CLINICAL LECTURESHIP IN GASTROENTEROLOGY FURTHER PARTICULARS 1. The Department of Medicine The Appointment The appointments committee for clinical lectures in the School of Clinical Medicine invite applications for a post in Gastroenterology, with specific research interest in Hepatology, in the Department of Medicine, commencing 1st October 2012. Applicants should have had suitable experience and training in Gastroenterology and Hepatology. They should be of the standing required for an Honorary Contract of Service with the NHS East of England as a Specialist Registrar. The appointment will be for 4 years. The successful candidate will be recommended for an honorary clinical contract with the Cambridge University Hospital NHS Foundation Trust. The Clinical Lecturer will be required to undertake research, clinical work and training and also teaching duties as assigned by the Head of Department, the Professor of Medicine (Ken G.C. Smith). The field of research will be determined by the successful applicant in discussion with the Head of Department (Professor Ken G.C. Smith). The Clinical Lectureship is aimed at doctors with a PhD/MD (or equivalent), who already have core specialty training experience, have gained the MRCP and show outstanding potential for continuing a career in academic medicine. It provides opportunities for post-higher degree research and facilitates applications for further research funding and postdoctoral academic training for doctors working towards completion of specialty training. Clinical Lecturers (CLs) spend 50% of their time undertaking specialist clinical training and 50% undertaking research. It is expected that CLs will complete their specialty training during the period of the Lectureship. The speciality training programme to be followed will be determined by the successful applicant in discussion with relevant members of the operational board of the Deanery Postgraduate School of Gastroenterology. Eligibility for CL: The post is open to doctors who have completed a PhD/MD Fellowship (or equivalent) or an MB PhD programme, have gained the Membership of the Royal College of Psychiatrists (or equivalent) and who meet the entry criteria for entry into specialty training. Appraisal for CL: There will be joint academic and clinical appraisal according to Follett principles with assessment, according to College and Deanery recommendations for Clinical Lecturers. 2. Biomedical research at the University of Cambridge The School of Clinical Medicine at the University of Cambridge (‘the Clinical School’) is one of the UK’s leading Medical Schools. Its strength is built on close relationships with pre-clinical science, on the one hand; and on translational partnerships with NHS organisations on the other. Excellence in Partnership The Clinical School is a member of Cambridge University Health Partners, a partnership between the University of Cambridge, Cambridge University Hospitals NHS Foundation Trust (the main acute trust for Cambridge), Papworth Hospital NHS Foundation Trust (a specialist Cardio-Thoracic Trust) and the Cambridge and Peterborough NHS Foundation Trust (the regional Trust responsible for Mental Health). Cambridge University Health Partners has been awarded ‘Academic Health Science Centre Status’ in recognition of its excellence in research education and clinical service, and of the close working relationships between the partners which enable this excellence to be achieved. Cambridge University Health Partners is based on the Cambridge Biomedical Campus. This campus hosts activities from all four of the partners, and is the main physical site for two of them. It also hosts Institutes and Units run by other bodies which make major contributions to the richness of the environment. These include the Medical Research Council, Cancer Research UK and GlaxoSmithKline. Together, the partners are intending to double the size of the Cambridge Biomedical Campus by 2020. New developments will include additional clinical space to accommodate expansion and improvement of healthcare, including the relocation of Papworth Hospital, new research space associated with the clinical developments, and a commercial biomedical science park. Through the University of Cambridge, CUHP has access to a wealth of pre-clinical excellence, both in Clinical School Departments and Institutes, and in the School of the Biological Sciences. Excellence in Research The School’s research strategy has identified a number of strategic themes, which are aligned with the strategic themes of the School of the Biological Sciences and our NHS partners. These are: - Cancer - Cardiovascular science and medicine - Developmental and regenerative biology and medicine - Epidemiology and public health - Functional genomics, systems biology and genetic medicine - Infection and immunity - Medical Imaging - Metabolic medicine, integrative and comparative physiology - Neuroscience, psychology and mental health - Women’s health Further information may be found at: http://www.biomed.cam.ac.uk/research/ In the 2008 RAE, the University of Cambridge made submissions to 7 out of 8 of the Units of Assessment under Main Panel’s A and B, and achieved the following quality profiles: Percentage of research activity in the submission judged to meet the FTE standard for: Unit of Assessment Category A 4* 3* 2* 1* U/C 1 - Cardiovascular Medicine 14 35 50 10 5 0 2 - Cancer Studies 33.5 35 45 15 5 0 3 - Infection and Immunology 46 35 45 15 0 5 4 - Other Hospital Based Clinical Subjects 53.7 35 45 20 0 0 5 - Other Laboratory Based Clinical Subjects 40.55 45 40 10 5 0 6 - Epidemiology and Public Health 10 40 45 15 0 0 8 - Primary Care and Other Community Based Clinical Subjects 5.2 20 45 30 5 0 9 - Psychiatry, Neuroscience and Clinical Psychology 40.8 40 40 15 5 0 243.75 Overall, Cambridge Medicine achieved a Grade Point Average of 3.14, and was ranked first in the THES league table. Together with our NHS partners, we have been awarded significant NIHR funding. Cambridge University NHS Foundation Trust hosts one of five Comprehensive Biomedical Research Centres (BRCs), and Cambridgeshire and Peterborough NHS Trust hosts one of five Collaborations for Leadership in Applied Health Research and Care (CLAHRCs). The School hosts three MRC Centres: The MRC Centre for Obesity and Related Metabolic Diseases, the MRC Centre for Stem Cells Biology and Regenerative Medicine, and the MRC Centre for Nutritional Epidemiology in Cancer Prevention and Survival. In addition The Institute of Public Health was chosen as one of five UK organisations to be awarded a UKCRC Public Health Centre of Excellence grant. The Cambridge centre is known as the Centre for Diet and Physical Activity Research. Excellence in Teaching Undergraduate medical education is delivered in partnership with the School of the Biological Sciences and a number of associated partner NHS Trusts and general practices throughout the eastern region. The university offers three integrated undergraduate medical education programmes leading to the MBBChir degree: 1. standard course: six years including a compulsory BA (Medical and Veterinary Sciences Tripos). 2. MBPhD course: extended standard course of nine years including the BA and a research period intercalated between years 4 and 5 leading to a PhD. 3. Cambridge Graduate Course in Medicine (CGC): accelerated four year programme for graduates with a first degree in any academic discipline. The university admits 280 students to the standard course. Initially based in the School of Biological Sciences, all students undertake two years of core biomedical science study, with additional input from the Clinical School to contextualise their scientific study and provide some early clinical experience. Year 3 is a further year of academic study leading to the University’s primary degree, the BA. Students then progress to clinical studies either in the School of Clinical Medicine, one of the London medical schools or Oxford. Over the last five years, Cambridge has become the clinical school of choice for our students, resulting in competition for clinical places. From 2012 intake, the School will admit 160 students to continue study in Cambridge; we hope to increase this number over the next few years. The Clinical School offers students a first class scientific approach to medicine combined with learning and teaching programmes that emphasize the development of excellence in the clinical, communication, practical and professional skills required for good medical practice. Based at the Cambridge University Hospitals NHS Trust (Addenbrookes Hospital) on the Biomedical Campus, the School promotes the benefits of learning medicine in a research – rich environment, offering all students opportunities to pursue their interests through the student–selected components and other project, research and independent study opportunities. Teaching also occurs in a network of partner NHS Trusts throughout the eastern region and a large number of associated general practices. These are linked by an enthusiastic and committed Clinical Sub-Deans group, the Clinical Skills Unit network and the School’s virtual learning environment, enabling simultaneous curriculum delivery across a wide range of sites. The School provides staff development and regular education and Quality Assurance visits to promote these partnerships in teaching and learning. Each year, between five and ten students admitted to the standard course are accepted onto the MBPhD programme. At the end of year 4, these students intercalate a PhD, with groups across the university and other local research institutions offering studentships. Throughout their doctoral studies, students continue to receive clinical supervisions and seminars. Having completed their PhD, MBPhD students are integrated into the final two years of the CGC clinical programme. The CGC provides a graduate entry route for 20 academically able students whose first degree may be in any subject, not restricted to biomedical science. During the first two years students undertake the standard core biomedical science programme, spending the vacation time following a bespoke programme of clinical study based at West Suffolk Hospital and a small number of specially selected GP practices. The final two years are largely integrated with the standard programme with the final year for CGC and MBPhD students based at West Suffolk. The School maintains close links with our local NHS postgraduate education community through the CUHP and good working relationships with the Postgraduate Deanery team and East Anglia Foundation School. Looking forward, the establishment of strong partnerships in the local health economy provide security for student placements and continuity between undergraduate and postgraduate medical education. Establishment of the Clinical Academic Training Office within the School has further enhanced opportunities for seamless clinical academic education, particularly providing career structure and guidance for students wishing to pursue combined clinical and research – based training. The University provides exciting and varied programmes for medical students. Outcome measures have demonstrated significant improvement in national ranking when Clinical School graduates are asked about their preparedness for being a doctor (placing Cambridge now in the top 10 of all UK medical schools for this indicator) and over 90% of our students have been placed in their first choice Foundation School since the introduction of the national selection process. Most importantly, we now have very high levels of student satisfaction, both in internal feedback and in the National Student Survey, rising from 67% overall satisfaction in 2008 to 93% in 2011. Organisation of the School Internally, the School is organised on a departmental basis, with Departments mapping closely onto the clinical directorate structures of our NHS partners: - Clinical Biochemistry - Clinical Neurosciences - Haematology - Medical Genetics - Medicine - Obstetrics and Gynaecology - Oncology - Paediatrics - Public Health and Primary Care - Psychiatry - Radiology - Surgery Alongside departments, the School maintains a number of cross-departmental Institutes to bring together researchers with cognate interest. At present, there are three Institutes, with a fourth (in Cardio-Respiratory Medicine) planned. - Cambridge Institute of Medical Research - Institute of Metabolic Sciences - Institute of Public Health 3. Academic Gastroenterology and Hepatology in Cambridge The Department of Medicine, headed by Professor Ken Smith (email@example.com), comprises a number of Divisions each involved in research related to human disease with a substantial number of research associates, postgraduate students and technical staff. Non- clinical and clinical research staff work on common problems, and postgraduate students are also a mix of both clinical and non-clinical workers. The Department has a large and active research programme whose broad aim is to understand disease processes at the molecular level and apply this knowledge to clinical management. The principal research interests of the Department by Division are: Gastroenterology and Hepatology (Professor A. Kaser, Dr M. Parkes, Dr R. Fitzgerald, Dr G. Alexander and colleagues) – research interests highlighted below. Renal Medicine The study of immune regulation and autoimmune disease (both basic immunobiology and a translational medicine programme; Professor K.G.C. Smith and colleagues) and endothelial cell biology (Dr. J. Bradley), in relation to renal disease. See http://www.med.cam.ac.uk/nephrology/index.html Wellcome Immunology UnitIn vivo and in vitro studies of T cell memory (Professor D.T. Fearon and colleagues). Rheumatology The immunology and pathogenesis of inflammatory joint diseases (Professor J.S.H. Gaston Dr. Frances Hall and colleagues). Infectious Disease The molecular virology, immunology and pathogenesis of persistent virus infections - including herpesviruses and retroviruses (Professor A.M.L. Lever, Professor. J.H. Sinclair, Professor Paul Lehner, Professor J.G.P. Sissons and colleagues). Dermatology Pathogenesis of cutaneous papilloma virus infections (Dr. J. Sterling). Metabolic Medicine The biochemical genetics, molecular pathogenesis and treatment of inborn errors of metabolism (Professor T.M. Cox, Dr.P.B.Deegan and colleagues). Diabetes and Endocrinology Genetic endocrinology including nuclear hormone receptors and human disease (Professor K. Chatterjee, Dr.M.Gurnell, Dr.M. Evans and colleagues). Bone Research The cellular, molecular and endocrine mechanisms of osteoporosis and bone disease (Professor J. Compston, Dr. N. Loveridge, Dr. J. Reeve and colleagues). Cardiovascular Medicine. The study of the cellular and molecular aspects of vascular disease (Professor M. Bennett). The role of cytokines in autoimmune and cardiovascular diseases (Dr. D. Grainger). The Clinical Pharmacology Unit (Professor M.J. Brown and colleagues) The pathogenesis and genetics of high blood pressure. Respiratory Medicine Inflammatory lung disease – in particular granulocyte biology (Professor E.R. Chilvers), -antitrypsin structure/function and pulmonary vascular remodelling (Dr. N. Morrell). The role of conformational transitions of proteins in disease (Professor D. Lomas). The Anaesthetics Unit is also attached to the Department of Medicine. Current research in the Unit (Professor D.K. Menon) focuses on metabolic imaging of brain injury and inflammatory processes in acute brain injury. There are excellent opportunities for research. The successful applicant will usually have research interest in gastroenterology and/or hepatology in its broadest sense. This might involve work in the Division of Gastroenterology and Hepatology, but could also include research in any of the Departments or Institutes associated with the University of Cambridge. Professor Arthur Kaser heads the Division of Gastroenterology and Hepatology, and he and his colleagues pursue work on the mucosal immunological basis of inflammatory bowel diseases. In particular they have a profound interest in the relationship between the intestinal microbiota and the host, and the epithelium in-between these compartments. Close ties to the Wellcome Trust Sanger Institute (Professor Gordon Dougan, Dr Trevor Lawley, Dr Simon Clare) exist that relate to the genomic study of the intestinal microbiota, as well as to functional studies involving gnotobiotic approaches. Further interest relates to the fundamental biology of the biliary epithelium and hence liver disease. This group employs genetic murine models to gain insight into basic mechanisms of mucosal homeostasis and disease, and aims at transforming genetic insight into fundamental functional insight into disease and further into translational opportunities for patients. Dr Miles Parkes and his group investigate the fundamental genetic basis of inflammatory bowel disease, again in close collaboration with the Wellcome Trust Sanger Institute (Dr Carl A Anderson, Dr Jeffrey Barrett) as well as the UK IBD genetics consortium. In addition, this group aims at translational approaches in the context of clinical trials attached to the NHS clinical service. The programme of Dr M Parkes will work closely together with that of Arthur Kaser and form part of the emerging theme of inflammation and immunity overseen by Professor Ken Smith in the Department of Medicine. Professor Ken Smith (Dept of Medicine, and Renal Medicine and Immunology) and colleagues collaborate with Dr M Parkes in their investigations into applying novel techniques (such as micro-array analysis) to analysing therapeutic responses in patients with autoimmune diseases within their “translational medicine” programme. Dr Rebecca Fitzgerald (based in the MRC Cancer Cell Unit; Dept of Oncology; NHS Dept of Gastroenterology) and colleagues investigate the molecular pathogenesis and progression of Barrett’s disease and oesophageal cancer - and in so doing to provide tools for early diagnosis, accurate prognostication and therapy which can be applied to clinical practice. Alongside basic laboratory projects this group have a number of clinical trials including Barrett’s Oesophagus gene study and Trimodal Imaging and Molecular endpoints which are both registered on the NIHR portfolio. Further details can be found on: http://www.hutchison-mrc.cam.ac.uk/Research/Rebecca_Fitzgerald/index.html. Dr Graeme Alexander and colleagues study chronic liver disease with special interest in viral hepatitis and hepatocellular carcinoma. In collaboration with Dr Richard Sanford in Medical Genetics Dr Alexander has spearheaded a UK genome-wide association study of primary biliary cirrhosis and primary sclerosing cholangitis with the largest assembled cohorts of patients worldwide to date. Dr Alexander Gimson and colleagues investigate liver transplantation outcomes and the genetic basis of chronic liver disease. Further research interests in hepatology relate to NAFLD and alcoholic liver disease (Dr Michael Allison) and inherited liver disease (Dr Bill Griffiths). Further research opportunities within gastroenterology arise from the fact that Cambridge is a centre for National Bowel Cancer Screening (Dr. Ewen Cameron) and a national centre for Transplantation (Dr. Steve Middleton). There are collaborative research programmes ongoing, for example in coeliac disease (Prof. Ming Du, Dept. Pathology with Dr. Jeremy Woodward, Gastroenterology). In addition to the scientific programmes and research opportunities mentioned above which are directly or indirectly affiliated with the Department of Medicine and the Division of Gastroenterology and Hepatology within the Department, numerous other Departments and Institutes on campus have research interests that fall in the wider field of gastroenterology and hepatology or might relate to this field. Examples of such include research on the metabolic syndrome, stem cell biology, epithelial development and differentiation, microbial community structures and host-pathogen interaction, and innumerable others. Such work might be performed by research groups also located in the Institute of Metabolic Science (IMS), the Cambridge Institute of Medical Research, the Cancer Research UK Cambridge Research Institute, The Wellcome Trust Sanger Institute, as well as many others within, affiliated with, or collaborating with the University of Cambridge and its School of Clinical Medicine. The main sources of research funding of the Division of Gastroenterology and Hepatology are from the Wellcome Trust (WTCCC3), from the European Research Council (ERC), and translational initiatives are supported through the NIHR Cambridge Biomedical Research Centre (Director Dr John Bradley). The Lecturer will be required to attract outside funding for research. 4. Clinical Training Gastroenterology The East Anglia area is mainly rural and covers the counties of Norfolk, Suffolk and Cambridgeshire with a population of around 3 million. The Deanery training area also includes the counties of Bedfordshire, Essex and Hertfordshire. Training and Supervision Clinical training is supervised by the Higher Training Committee overseen by the East of England Deanery. They will carry out an Annual Review of each trainee’s progress. The specific learning objectives set for each placement will be appraised at this review. The trainees will be expected to maintain a logbook of experience gained to support their learning objectives. In addition the clinical lecturer will keep an account of teaching feed- back from students and progress in research activity which will form part of their overall annual review. 5. Clinical Lectureships – general conditions of appointment a) Medical Defence All staff actively engaged in the practice of medicine are required by the University to obtain medical defence cover appropriate for their activities. Evidence of such membership must be produced to the Secretary's office on taking up appointment. b) Clinical Lectureships Clinical Lectureships are limited tenure academic appointments which are held at honorary NHS Specialist Registrar level, or equivalent. They are intended for doctors interested in a medical academic career; the duties combine teaching, clinical work and research before proceeding to a more senior appointment either in academic medicine or in the National Health Service. Arrangements will be made to provide clinical training facilities which will meet the requirements for CCT including, where appropriate, clinical experience in hospitals elsewhere than Cambridge. Clinical Lecturers are expected to fulfil the role of Clinical Supervisor to a group of clinical students. Clinical Lecturers may be eligible to receive non-pensionable payments for extra duty; the number is determined by the relevant Hospital. Appointments to Clinical Lectureships are made for four years in the first instance with the possibility of re-appointment for up to two years. Clinical Lecturers are entitled to six weeks' leave (including Bank Holidays) to be taken by arrangement with the Head of Department and head of Service, and must be willing to provide clinical and teaching cover for University and NHS colleagues in the event of sickness or absence. c) General Scales of stipends for University Officers are determined by the University from time to time and normally reflect nationally negotiated agreements. The Notices advertising vacancies and the further particulars of such posts will show the scales in force at the particular time. Applicants for posts may be asked to provide additional information to enable starting salaries to be determined. Staff appointed to posts with clinical duties and responsibilities must hold an Honorary NHS Contract for which application will be made by the Head of Department/in liaison with the School Office. Contribution Reward Scheme The University operates an annual contribution reward scheme for non-academic staff. The scheme is made up of two components: i. Contribution Increments (for sustained/ongoing contribution) ii. Single Contribution Payments (for one-off/time limited contribution) All appointments are subject to the Statutes and Ordinances of the University. Probation – all appointments are subject to an initial period of employment unless waived by the authority concerned. College duties - Staff with clinical responsibility are precluded by Ordinance from holding certain College offices. Superannuation - Eligible for membership of the Universities Superannuation Scheme or may be eligible to remain in the NHS Superannuation Scheme. Residence - Officers are required to reside within 20 miles of Great St Mary's Church; application can be made to the General Board for permission to live outside this limit through the Head of Department and Chairman of the Faculty Board of Clinical Medicine. d) Staff Review and Development (Appraisal) (SRD) Details of the University's SRD scheme, whose purpose is to enhance work effectiveness and facilitate career development, are given in an information sheet (which is included in starter packs for new members of staff) and a booklet answering frequently asked questions. These are available in hard copy from the Human Resources Division or can be downloaded: http://www.admin.cam.ac.uk/offices/hr/policy/appraisal/ For new staff the University operates schemes for mentoring, assistance and assessment during the probationary period or fixed-term appointment, and for staff appraisal. Arrangements have been developed for joint University and NHS appraisal of those holding Honorary NHS contracts. Details are available from the Head of Department. For those University Officers who have Honorary Consultant contracts with NHS Trusts or who provide clinical sessions under Service Level Agreements, the responsibility for the performance of their clinical duties rests with the relevant NHS Trust. University Officers will be subject to the Trust’s policies and disciplinary procedures for the performance of their clinical duties, in consultation with the University as primary employer. e) Staff Development The University manages an annual programme covering a range of areas including supervising and lecturing, and conducting staff appraisal. In addition the Director of Medical Education oversees staff development in relation to the teaching of clinical medical students. Staff new to teaching are strongly advised to attend courses on clinical teaching. f) Family Friend Policies, including Flexible Working The University has a range of family friendly policies. Advice on procedures and further information may be obtained from : http://www.admin.cam.ac.uk/offices/hr/policy/flexible/. g) Pre-employment screening The University and the NHS have policies on pre-employment health screening; appointments to offices where duties involve certain activities will be made conditional upon a satisfactory health screen. The NHS also requires certain pre- employment checks. The University issues papers to candidates for University posts with clinical duties on behalf of the NHS. h) Equal Opportunities Policy and Codes of Practice http://www.admin.cam.ac.uk/offices/hr/policy/equal.html The University of Cambridge is committed in its pursuit of academic excellence to equality of opportunity and to a pro-active and inclusive approach to equality, which supports and encourages all under-represented groups, promotes an inclusive culture, and values diversity. The University is therefore committed to a policy and practice which require that, for students, admission to the University and progression within undergraduate and graduate studies, will be determined only by personal merit and by performance. For staff, entry into employment with the University and progression within employment will be determined only by personal merit and by the application of criteria which are related to the duties and conditions of each particular post and the needs of the institution concerned. Subject to statutory provisions no applicant for admission as a student, or for a staff appointment, or student, or member of staff, will be treated less favourably than another on the grounds of sex (including gender reassignment), marital or parental status, race, ethnic or national origin, colour, disability, sexual orientation, religion, or age. For students, ability to meet the requirements of the selection criteria for competitive admission and for staff, ability to perform the job, will be the primary consideration. 6. Applications Further application information about the post can be found at http://www.medschl.cam.ac.uk/jobs/?p=1526 Email your completed CHRIS 6 application from in the MS WORD (including details of three referees who may be consulted before interview), covering letter, Curriculum Vitae, FPS Form, CCT Form and Declaration Form to firstname.lastname@example.org by 5pm on the deadline Monday 28 May 2012.
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