Contribution Reward Scheme by vUR7N8


                                 FURTHER PARTICULARS

1.   The Department of Medicine

     The Appointment

     The appointments committee for clinical lectures in the School of Clinical Medicine invite
     applications for a post in Gastroenterology, with specific research interest in Hepatology, in
     the Department of Medicine, commencing 1st October 2012. Applicants should have had
     suitable experience and training in Gastroenterology and Hepatology. They should be of the
     standing required for an Honorary Contract of Service with the NHS East of England as a
     Specialist Registrar. The appointment will be for 4 years. The successful candidate will be
     recommended for an honorary clinical contract with the Cambridge University Hospital NHS
     Foundation Trust.

     The Clinical Lecturer will be required to undertake research, clinical work and training and
     also teaching duties as assigned by the Head of Department, the Professor of Medicine (Ken
     G.C. Smith). The field of research will be determined by the successful applicant in discussion
     with the Head of Department (Professor Ken G.C. Smith).

     The Clinical Lectureship is aimed at doctors with a PhD/MD (or equivalent), who already have
     core specialty training experience, have gained the MRCP and show outstanding potential for
     continuing a career in academic medicine. It provides opportunities for post-higher degree
     research and facilitates applications for further research funding and postdoctoral academic
     training for doctors working towards completion of specialty training. Clinical Lecturers (CLs)
     spend 50% of their time undertaking specialist clinical training and 50% undertaking
     research. It is expected that CLs will complete their specialty training during the period of the
     Lectureship. The speciality training programme to be followed will be determined by the
     successful applicant in discussion with relevant members of the operational board of the
     Deanery Postgraduate School of Gastroenterology.

     Eligibility for CL:
     The post is open to doctors who have completed a PhD/MD Fellowship (or equivalent) or an
     MB PhD programme, have gained the Membership of the Royal College of Psychiatrists (or
     equivalent) and who meet the entry criteria for entry into specialty training.

     Appraisal for CL:
     There will be joint academic and clinical appraisal according to Follett principles with
     assessment, according to College and Deanery recommendations for Clinical Lecturers.

2.   Biomedical research at the University of Cambridge

     The School of Clinical Medicine at the University of Cambridge (‘the Clinical School’) is one of
     the UK’s leading Medical Schools. Its strength is built on close relationships with pre-clinical
     science, on the one hand; and on translational partnerships with NHS organisations on the
Excellence in Partnership

The Clinical School is a member of Cambridge University Health Partners, a partnership
between the University of Cambridge, Cambridge University Hospitals NHS Foundation Trust
(the main acute trust for Cambridge), Papworth Hospital NHS Foundation Trust (a specialist
Cardio-Thoracic Trust) and the Cambridge and Peterborough NHS Foundation Trust (the
regional Trust responsible for Mental Health).

Cambridge University Health Partners has been awarded ‘Academic Health Science Centre
Status’ in recognition of its excellence in research education and clinical service, and of the
close working relationships between the partners which enable this excellence to be

Cambridge University Health Partners is based on the Cambridge Biomedical Campus. This
campus hosts activities from all four of the partners, and is the main physical site for two of
them. It also hosts Institutes and Units run by other bodies which make major contributions
to the richness of the environment. These include the Medical Research Council, Cancer
Research UK and GlaxoSmithKline. Together, the partners are intending to double the size of
the Cambridge Biomedical Campus by 2020. New developments will include additional
clinical space to accommodate expansion and improvement of healthcare, including the
relocation of Papworth Hospital, new research space associated with the clinical
developments, and a commercial biomedical science park.

Through the University of Cambridge, CUHP has access to a wealth of pre-clinical excellence,
both in Clinical School Departments and Institutes, and in the School of the Biological

Excellence in Research

The School’s research strategy has identified a number of strategic themes, which are aligned
with the strategic themes of the School of the Biological Sciences and our NHS partners.
These are:

-   Cancer
-   Cardiovascular science and medicine
-   Developmental and regenerative biology and medicine
-   Epidemiology and public health
-   Functional genomics, systems biology and genetic medicine
-   Infection and immunity
-   Medical Imaging
-   Metabolic medicine, integrative and comparative physiology
-   Neuroscience, psychology and mental health
-   Women’s health

Further information may be found at:

In the 2008 RAE, the University of Cambridge made submissions to 7 out of 8 of the Units of
Assessment under Main Panel’s A and B, and achieved the following quality profiles:
                                                                            Percentage of research activity in the
                                                                               submission judged to meet the
                                                                     FTE               standard for:
Unit of Assessment                                             Category A       4*      3*      2*      1*     U/C
1 - Cardiovascular Medicine                                           14        35      50      10       5       0
2 - Cancer Studies                                                  33.5        35      45      15       5       0
3 - Infection and Immunology                                          46        35      45      15       0       5
4 - Other Hospital Based Clinical Subjects                          53.7        35      45      20       0       0
5 - Other Laboratory Based Clinical Subjects                       40.55        45      40      10       5       0
6 - Epidemiology and Public Health                                    10        40      45      15       0       0
8 - Primary Care and Other Community Based Clinical Subjects         5.2        20      45      30       5       0
9 - Psychiatry, Neuroscience and Clinical Psychology                40.8        40      40      15       5       0


Overall, Cambridge Medicine achieved a Grade Point Average of 3.14, and was ranked first in
the THES league table.

Together with our NHS partners, we have been awarded significant NIHR funding. Cambridge
University NHS Foundation Trust hosts one of five Comprehensive Biomedical Research
Centres (BRCs), and Cambridgeshire and Peterborough NHS Trust hosts one of five
Collaborations for Leadership in Applied Health Research and Care (CLAHRCs).

The School hosts three MRC Centres: The MRC Centre for Obesity and Related Metabolic
Diseases, the MRC Centre for Stem Cells Biology and Regenerative Medicine, and the MRC
Centre for Nutritional Epidemiology in Cancer Prevention and Survival. In addition The
Institute of Public Health was chosen as one of five UK organisations to be awarded a UKCRC
Public Health Centre of Excellence grant. The Cambridge centre is known as the Centre for
Diet and Physical Activity Research.

Excellence in Teaching

Undergraduate medical education is delivered in partnership with the School of the
Biological Sciences and a number of associated partner NHS Trusts and general practices
throughout the eastern region. The university offers three integrated undergraduate medical
education programmes leading to the MBBChir degree:

     1. standard course: six years including a compulsory BA (Medical and Veterinary
        Sciences Tripos).
     2. MBPhD course: extended standard course of nine years including the BA and a
        research period intercalated between years 4 and 5 leading to a PhD.
     3. Cambridge Graduate Course in Medicine (CGC): accelerated four year programme for
        graduates with a first degree in any academic discipline.

The university admits 280 students to the standard course. Initially based in the School of
Biological Sciences, all students undertake two years of core biomedical science study, with
additional input from the Clinical School to contextualise their scientific study and provide
some early clinical experience. Year 3 is a further year of academic study leading to the
University’s primary degree, the BA. Students then progress to clinical studies either in the
School of Clinical Medicine, one of the London medical schools or Oxford. Over the last five
years, Cambridge has become the clinical school of choice for our students, resulting in
competition for clinical places. From 2012 intake, the School will admit 160 students to
continue study in Cambridge; we hope to increase this number over the next few years.
The Clinical School offers students a first class scientific approach to medicine combined with
learning and teaching programmes that emphasize the development of excellence in the
clinical, communication, practical and professional skills required for good medical practice.
Based at the Cambridge University Hospitals NHS Trust (Addenbrookes Hospital) on the
Biomedical Campus, the School promotes the benefits of learning medicine in a research –
rich environment, offering all students opportunities to pursue their interests through the
student–selected components and other project, research and independent study
opportunities. Teaching also occurs in a network of partner NHS Trusts throughout the
eastern region and a large number of associated general practices. These are linked by an
enthusiastic and committed Clinical Sub-Deans group, the Clinical Skills Unit network and the
School’s virtual learning environment, enabling simultaneous curriculum delivery across a
wide range of sites. The School provides staff development and regular education and
Quality Assurance visits to promote these partnerships in teaching and learning.

Each year, between five and ten students admitted to the standard course are accepted onto
the MBPhD programme. At the end of year 4, these students intercalate a PhD, with groups
across the university and other local research institutions offering studentships. Throughout
their doctoral studies, students continue to receive clinical supervisions and seminars.
Having completed their PhD, MBPhD students are integrated into the final two years of the
CGC clinical programme.

The CGC provides a graduate entry route for 20 academically able students whose first
degree may be in any subject, not restricted to biomedical science. During the first two years
students undertake the standard core biomedical science programme, spending the vacation
time following a bespoke programme of clinical study based at West Suffolk Hospital and a
small number of specially selected GP practices. The final two years are largely integrated
with the standard programme with the final year for CGC and MBPhD students based at
West Suffolk.

The School maintains close links with our local NHS postgraduate education community
through the CUHP and good working relationships with the Postgraduate Deanery team and
East Anglia Foundation School. Looking forward, the establishment of strong partnerships in
the local health economy provide security for student placements and continuity between
undergraduate and postgraduate medical education. Establishment of the Clinical Academic
Training Office within the School has further enhanced opportunities for seamless clinical
academic education, particularly providing career structure and guidance for students
wishing to pursue combined clinical and research – based training.

The University provides exciting and varied programmes for medical students. Outcome
measures have demonstrated significant improvement in national ranking when Clinical
School graduates are asked about their preparedness for being a doctor (placing Cambridge
now in the top 10 of all UK medical schools for this indicator) and over 90% of our students
have been placed in their first choice Foundation School since the introduction of the
national selection process. Most importantly, we now have very high levels of student
satisfaction, both in internal feedback and in the National Student Survey, rising from 67%
overall satisfaction in 2008 to 93% in 2011.

Organisation of the School

Internally, the School is organised on a departmental basis, with Departments mapping
closely onto the clinical directorate structures of our NHS partners:
     -   Clinical Biochemistry
     -   Clinical Neurosciences
     -   Haematology
     -   Medical Genetics
     -   Medicine
     -   Obstetrics and Gynaecology
     -   Oncology
     -   Paediatrics
     -   Public Health and Primary Care
     -   Psychiatry
     -   Radiology
     -   Surgery

     Alongside departments, the School maintains a number of cross-departmental Institutes to
     bring together researchers with cognate interest. At present, there are three Institutes, with
     a fourth (in Cardio-Respiratory Medicine) planned.

     -   Cambridge Institute of Medical Research
     -   Institute of Metabolic Sciences
     -   Institute of Public Health

3.   Academic Gastroenterology and Hepatology in Cambridge

     The Department of Medicine, headed by Professor Ken Smith (,
     comprises a number of Divisions each involved in research related to human disease with a
     substantial number of research associates, postgraduate students and technical staff. Non-
     clinical and clinical research staff work on common problems, and postgraduate students are
     also a mix of both clinical and non-clinical workers. The Department has a large and active
     research programme whose broad aim is to understand disease processes at the molecular
     level and apply this knowledge to clinical management. The principal research interests of
     the Department by Division are:

             Gastroenterology and Hepatology (Professor A. Kaser, Dr M. Parkes, Dr R. Fitzgerald,
     Dr G. Alexander and colleagues) – research interests highlighted below.
             Renal Medicine The study of immune regulation and autoimmune disease (both
     basic immunobiology and a translational medicine programme; Professor K.G.C. Smith and
     colleagues) and endothelial cell biology (Dr. J. Bradley), in relation to renal disease. See
             Wellcome Immunology UnitIn vivo and in vitro studies of T cell memory (Professor
     D.T. Fearon and colleagues).
             Rheumatology The immunology and pathogenesis of inflammatory joint diseases
     (Professor J.S.H. Gaston Dr. Frances Hall and colleagues).
             Infectious Disease The molecular virology, immunology and pathogenesis of
     persistent virus infections - including herpesviruses and retroviruses (Professor A.M.L. Lever,
     Professor. J.H. Sinclair, Professor Paul Lehner, Professor J.G.P. Sissons and colleagues).
             Dermatology Pathogenesis of cutaneous papilloma virus infections (Dr. J. Sterling).
             Metabolic Medicine The biochemical genetics, molecular pathogenesis and
     treatment of inborn errors of metabolism (Professor T.M. Cox, Dr.P.B.Deegan and
             Diabetes and Endocrinology Genetic endocrinology including nuclear hormone
receptors and human disease (Professor K. Chatterjee, Dr.M.Gurnell, Dr.M. Evans and
        Bone Research The cellular, molecular and endocrine mechanisms of osteoporosis
and bone disease (Professor J. Compston, Dr. N. Loveridge, Dr. J. Reeve and colleagues).
        Cardiovascular Medicine. The study of the cellular and molecular aspects of vascular
disease (Professor M. Bennett). The role of cytokines in autoimmune and cardiovascular
diseases (Dr. D. Grainger).
        The Clinical Pharmacology Unit (Professor M.J. Brown and colleagues) The
pathogenesis and genetics of high blood pressure.
        Respiratory Medicine Inflammatory lung disease – in particular granulocyte biology
(Professor E.R. Chilvers), -antitrypsin structure/function and pulmonary vascular
remodelling (Dr. N. Morrell). The role of conformational transitions of proteins in disease
(Professor D. Lomas).
        The Anaesthetics Unit is also attached to the Department of Medicine. Current
research in the Unit (Professor D.K. Menon) focuses on metabolic imaging of brain injury and
inflammatory processes in acute brain injury.

There are excellent opportunities for research. The successful applicant will usually have
research interest in gastroenterology and/or hepatology in its broadest sense. This might
involve work in the Division of Gastroenterology and Hepatology, but could also include
research in any of the Departments or Institutes associated with the University of Cambridge.
Professor Arthur Kaser heads the Division of Gastroenterology and Hepatology, and he and
his colleagues pursue work on the mucosal immunological basis of inflammatory bowel
diseases. In particular they have a profound interest in the relationship between the
intestinal microbiota and the host, and the epithelium in-between these compartments.
Close ties to the Wellcome Trust Sanger Institute (Professor Gordon Dougan, Dr Trevor
Lawley, Dr Simon Clare) exist that relate to the genomic study of the intestinal microbiota, as
well as to functional studies involving gnotobiotic approaches. Further interest relates to the
fundamental biology of the biliary epithelium and hence liver disease. This group employs
genetic murine models to gain insight into basic mechanisms of mucosal homeostasis and
disease, and aims at transforming genetic insight into fundamental functional insight into
disease and further into translational opportunities for patients. Dr Miles Parkes and his
group investigate the fundamental genetic basis of inflammatory bowel disease, again in
close collaboration with the Wellcome Trust Sanger Institute (Dr Carl A Anderson, Dr Jeffrey
Barrett) as well as the UK IBD genetics consortium. In addition, this group aims at
translational approaches in the context of clinical trials attached to the NHS clinical service.
The programme of Dr M Parkes will work closely together with that of Arthur Kaser and form
part of the emerging theme of inflammation and immunity overseen by Professor Ken Smith
in the Department of Medicine. Professor Ken Smith (Dept of Medicine, and Renal Medicine
and Immunology) and colleagues collaborate with Dr M Parkes in their investigations into
applying novel techniques (such as micro-array analysis) to analysing therapeutic responses
in patients with autoimmune diseases within their “translational medicine” programme. Dr
Rebecca Fitzgerald (based in the MRC Cancer Cell Unit; Dept of Oncology; NHS Dept of
Gastroenterology) and colleagues investigate the molecular pathogenesis and progression of
Barrett’s disease and oesophageal cancer - and in so doing to provide tools for early
diagnosis, accurate prognostication and therapy which can be applied to clinical practice.
Alongside basic laboratory projects this group have a number of clinical trials including
Barrett’s Oesophagus gene study and Trimodal Imaging and Molecular endpoints which are
both registered on the NIHR portfolio. Further details can be found on: Dr Graeme
Alexander and colleagues study chronic liver disease with special interest in viral hepatitis
     and hepatocellular carcinoma. In collaboration with Dr Richard Sanford in Medical Genetics
     Dr Alexander has spearheaded a UK genome-wide association study of primary biliary
     cirrhosis and primary sclerosing cholangitis with the largest assembled cohorts of patients
     worldwide to date. Dr Alexander Gimson and colleagues investigate liver transplantation
     outcomes and the genetic basis of chronic liver disease. Further research interests in
     hepatology relate to NAFLD and alcoholic liver disease (Dr Michael Allison) and inherited liver
     disease (Dr Bill Griffiths).

     Further research opportunities within gastroenterology arise from the fact that Cambridge is
     a centre for National Bowel Cancer Screening (Dr. Ewen Cameron) and a national centre for
     Transplantation (Dr. Steve Middleton). There are collaborative research programmes
     ongoing, for example in coeliac disease (Prof. Ming Du, Dept. Pathology with Dr. Jeremy
     Woodward, Gastroenterology).

     In addition to the scientific programmes and research opportunities mentioned above which
     are directly or indirectly affiliated with the Department of Medicine and the Division of
     Gastroenterology and Hepatology within the Department, numerous other Departments and
     Institutes on campus have research interests that fall in the wider field of gastroenterology
     and hepatology or might relate to this field. Examples of such include research on the
     metabolic syndrome, stem cell biology, epithelial development and differentiation, microbial
     community structures and host-pathogen interaction, and innumerable others. Such work
     might be performed by research groups also located in the Institute of Metabolic Science
     (IMS), the Cambridge Institute of Medical Research, the Cancer Research UK Cambridge
     Research Institute, The Wellcome Trust Sanger Institute, as well as many others within,
     affiliated with, or collaborating with the University of Cambridge and its School of Clinical

     The main sources of research funding of the Division of Gastroenterology and Hepatology are
     from the Wellcome Trust (WTCCC3), from the European Research Council (ERC), and
     translational initiatives are supported through the NIHR Cambridge Biomedical Research
     Centre (Director Dr John Bradley). The Lecturer will be required to attract outside funding for

4.   Clinical Training Gastroenterology

     The East Anglia area is mainly rural and covers the counties of Norfolk, Suffolk and
     Cambridgeshire with a population of around 3 million. The Deanery training area also
     includes the counties of Bedfordshire, Essex and Hertfordshire.

     Training and Supervision

     Clinical training is supervised by the Higher Training Committee overseen by the East of
     England Deanery. They will carry out an Annual Review of each trainee’s progress. The
     specific learning objectives set for each placement will be appraised at this review. The
     trainees will be expected to maintain a logbook of experience gained to support their
     learning objectives. In addition the clinical lecturer will keep an account of teaching feed-
     back from students and progress in research activity which will form part of their overall
     annual review.
5.   Clinical Lectureships – general conditions of appointment

     a)    Medical Defence

           All staff actively engaged in the practice of medicine are required by the University to
           obtain medical defence cover appropriate for their activities. Evidence of such
           membership must be produced to the Secretary's office on taking up appointment.

     b)    Clinical Lectureships

           Clinical Lectureships are limited tenure academic appointments which are held at
           honorary NHS Specialist Registrar level, or equivalent. They are intended for doctors
           interested in a medical academic career; the duties combine teaching, clinical work
           and research before proceeding to a more senior appointment either in academic
           medicine or in the National Health Service. Arrangements will be made to provide
           clinical training facilities which will meet the requirements for CCT including, where
           appropriate, clinical experience in hospitals elsewhere than Cambridge. Clinical
           Lecturers are expected to fulfil the role of Clinical Supervisor to a group of clinical
           students. Clinical Lecturers may be eligible to receive non-pensionable payments for
           extra duty; the number is determined by the relevant Hospital. Appointments to
           Clinical Lectureships are made for four years in the first instance with the possibility of
           re-appointment for up to two years. Clinical Lecturers are entitled to six weeks' leave
           (including Bank Holidays) to be taken by arrangement with the Head of Department
           and head of Service, and must be willing to provide clinical and teaching cover for
           University and NHS colleagues in the event of sickness or absence.

     c)    General

           Scales of stipends for University Officers are determined by the University from time
           to time and normally reflect nationally negotiated agreements. The Notices
           advertising vacancies and the further particulars of such posts will show the scales in
           force at the particular time. Applicants for posts may be asked to provide additional
           information to enable starting salaries to be determined. Staff appointed to posts
           with clinical duties and responsibilities must hold an Honorary NHS Contract for which
           application will be made by the Head of Department/in liaison with the School Office.

           Contribution Reward Scheme

           The University operates an annual contribution reward scheme for non-academic staff.
           The scheme is made up of two components:

           i.      Contribution Increments (for sustained/ongoing contribution)

           ii.     Single Contribution Payments (for one-off/time limited contribution)

           All appointments are subject to the Statutes and Ordinances of the University.

           Probation – all appointments are subject to an initial period of employment unless
           waived by the authority concerned.
     College duties - Staff with clinical responsibility are precluded by Ordinance from
     holding certain College offices.

     Superannuation - Eligible for membership of the Universities Superannuation Scheme
     or may be eligible to remain in the NHS Superannuation Scheme.

     Residence - Officers are required to reside within 20 miles of Great St Mary's Church;
     application can be made to the General Board for permission to live outside this limit
     through the Head of Department and Chairman of the Faculty Board of Clinical

d)   Staff Review and Development (Appraisal) (SRD)

     Details of the University's SRD scheme, whose purpose is to enhance work
     effectiveness and facilitate career development, are given in an information sheet
     (which is included in starter packs for new members of staff) and a booklet answering
     frequently asked questions. These are available in hard copy from the Human
     Resources Division or can be downloaded:

     For new staff the University operates schemes for mentoring, assistance and
     assessment during the probationary period or fixed-term appointment, and for staff

     Arrangements have been developed for joint University and NHS appraisal of those
     holding Honorary NHS contracts. Details are available from the Head of Department.

     For those University Officers who have Honorary Consultant contracts with NHS Trusts
     or who provide clinical sessions under Service Level Agreements, the responsibility for
     the performance of their clinical duties rests with the relevant NHS Trust. University
     Officers will be subject to the Trust’s policies and disciplinary procedures for the
     performance of their clinical duties, in consultation with the University as primary

e)   Staff Development

     The University manages an annual programme covering a range of areas including
     supervising and lecturing, and conducting staff appraisal. In addition the Director of
     Medical Education oversees staff development in relation to the teaching of clinical
     medical students. Staff new to teaching are strongly advised to attend courses on
     clinical teaching.

f)   Family Friend Policies, including Flexible Working

     The University has a range of family friendly policies. Advice on procedures and
     further information may be obtained from :

g)   Pre-employment screening
           The University and the NHS have policies on pre-employment health screening;
           appointments to offices where duties involve certain activities will be made
           conditional upon a satisfactory health screen. The NHS also requires certain pre-
           employment checks. The University issues papers to candidates for University posts
           with clinical duties on behalf of the NHS.

     h)    Equal Opportunities Policy and Codes of Practice

           The University of Cambridge is committed in its pursuit of academic excellence to
           equality of opportunity and to a pro-active and inclusive approach to equality, which
           supports and encourages all under-represented groups, promotes an inclusive culture,
           and values diversity.

           The University is therefore committed to a policy and practice which require that, for
           students, admission to the University and progression within undergraduate and
           graduate studies, will be determined only by personal merit and by performance. For
           staff, entry into employment with the University and progression within employment
           will be determined only by personal merit and by the application of criteria which are
           related to the duties and conditions of each particular post and the needs of the
           institution concerned.

           Subject to statutory provisions no applicant for admission as a student, or for a staff
           appointment, or student, or member of staff, will be treated less favourably than
           another on the grounds of sex (including gender reassignment), marital or parental
           status, race, ethnic or national origin, colour, disability, sexual orientation, religion, or
           age. For students, ability to meet the requirements of the selection criteria for
           competitive admission and for staff, ability to perform the job, will be the primary

6.   Applications

     Further application information about the post can be found at

     Email your completed CHRIS 6 application from in the MS WORD (including details of three
     referees who may be consulted before interview), covering letter, Curriculum Vitae, FPS
     Form, CCT Form and Declaration Form to by 5pm on the
     deadline Monday 28 May 2012.

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