Society of Toxicology
Southern California Chapter
President President’s Message
Husam Younis (Submitted by Husam Younis)
Vice President The Southern California Chapter of
Michelle Horner the Society of Toxicology (SCCSOT)
Amgen Inc has had another great year. SCCSOT
Vice President-Elect is the only dues free regional chapter
Robert Dunn and has successfully maintained this
Amgen Inc status since 2000. The chapter
firstname.lastname@example.org represents a diverse membership
Secretary from academia, biotechnology, the
Anthony M. Ndifor
Johnson & Johnson Inc pharmaceutical industry, and
email@example.com regulatory bodies, among others, to
Treasurer promote and support the discipline of
Tina Leakakos toxicology in Southern California.
Arena Pharmaceuticals Inc.
Councilor I would like to welcome three new
Gregory J. Stevens members to the SCCSOT council.
Pfizer Inc Robert Dunn will serve as Vice-
Councilor President Elect and Jacob Jabbour
Jacob Jabbour and Andrew Seacat have joined the
Neurocrine chapter as councilors. I appreciate
firstname.lastname@example.org their commitment to the chapter and
look forward to their participation.
Allergan Inc Thanks Robert, Jacob and Andrew
Seacat_andrew@allergan.com for joining our council. I also want to
Councilor/Past President thank the rest of the council members
Hisham K. Hamadeh for all their efforts in supporting the
email@example.com chapter’s goals and mission over the
Student Representative year(s). Special thanks are extended
Sudheer Beedanagari to our fearless Past-President,
UCLA Hisham Hamadeh, for his unrelenting
www Liasion engagement and dedication to the
Brian H Mathison chapter. He has significantly
firstname.lastname@example.org contributed to the chapter’s success.
2007 Annual SCCSOT Meeting Third Place ($100): Ilona Bebenek.
The 2007 SCCSOT Annual Meeting Exploring the Link between HIF-1
was held October 26th, 2007, at and Radioprotection. IG Bebenek,
Amgen Inc., in Thousand Oaks, CA. WH McBride and O. Hankinson.
The meeting’s theme was Molecular Toxicology Program,
Contribution of Physiological University of California, Los
Differences to Different Toxicity
Outcomes Across Species. Despite 2008 Annual SOT Meeting
the wild fires that plagued our region Highlights
and limited participation of San A joint reception between SCCSOT
Diego members, more than 80 and the Mountain West Chapter was
participants attended. This is a held on March 16, 2008 during the
testament to the quality of the Annual SOT meeting in Seattle, WA.
scientific meeting. It was held at a cozy venue. The
reception was well attended and
Awards were presented for members of both chapters in
outstanding student poster attendance had a great opportunity to
presentations at the meeting. There get to know each other. We look
were 10 student posters with forward to future joint functions with
participants representing UCLA, UC other regional chapters.
Irvine, and UC Riverside.
2008 Greater San Diego Science
First Place ($500): Sudheer and Engineering Fair
Beedanagari. Characterization of SCCSOT coordinated judging by
TCDD-Induced Histone local toxicologists at this annual
Modifications to Study the event on April 2, 2008, as part of the
Differential Regulation of the Human K-12 SOT Outreach Program. A
CYP1A1 and CYP1B1 Genes. special thanks to Diana Johnson (K-
Sudheer Beedanagari, Robert Taylor 12 Liason), Brad Hirakawa, and
and Oliver Hankinson. Molecular Husam Younis for serving as judges
Toxicology Program, University of at this event. We were all impressed
California, Los Angeles with the quality of the science by
these local high school students.
Second Place ($250): Yvonne SCCSOT awarded a $100 prize to
Hoang. Follicle–Stimulating Alex Santillan (Effect of Caffeine on
Hormone Increases Glutathione the Fertilization Rate of
Synthesis in Primary Rat Granulosa Strongylocentrotus purpuratus) and
Cells: Involvement of cAMP/PKA Mirriam Baterina (Effect of Copper
Pathway. Yvonne Hoang and Ulrike Contamination on Eisenia fetida
Luderer. Depts. of Medicine and Redworms).
Develoopmental and Cell Biology,
University of California,
Upcoming Events A Mounting Concern for Novel
Therapeutics. Please see the attached
2008 Annual SCCSOT Meeting meeting agenda and call for abstracts.
The SCCSOT is organizing a very In addition to the poster
exciting annual meeting for the fall presentations, we will also include
on October 2, 2008, at the UCSD student/Post-Doc oral presentations at
Faculty Club in San Diego, CA. The the 2008 annual meeting. I look
title of the meeting is Cardiotoxicity: forward to seeing you there.
SCCSOT Annual Meeting
A Mounting Concern for Novel Therapeutics
October 2, 2008
UCSD Faculty Club
9300 Gilman Drive MC0121
San Diego, CA 92903
Time Activity Speaker
9-9:15 Introduction & Welcome Husam Younis,
9:15-11:45 Session 1: Cardiotoxicity of Novel
9:15-10:15 Translational Ideas to Curb Side Effects in Ariel Fernandez,
Anticancer Kinase-Targeting Therapy: Rice University
Reducing Cardiotoxicity Through Inhibitor
10:15-11 Cardiotoxicity Associated With Tyrosine Bart Jessen, Pfizer
Kinase Inhibitors Inc.
11-11:45 Pre-clinical and Clinical Cardiovascular Eileen Blasi, Pfizer
Effects of the CEPT-inhibitor Torcetrapib Inc.
1:30-3:45 Session 2: Safety Testing for Cardiotoxicity
1:30-2:15 QT Prolongation: A Look Beyond the Aida Sacaan,
hERG Channel. Neurocrine Inc.
2:15-3 Transcriptomics to Aid Evaluation and Greg Falls, GSK
Prediction of Compound-Induced
3-3:45 TBD Hugo Vargas,
4-4:45 Session 3: Student/Post Doc presentation
4-4:15 Student/Post Doc presentation TBD
4:15-4:30 Student/Post Doc presentation TBD
4:30-4:45 Student/Post Doc presentation TBD
4:45-6:30 Reception/poster session
6:30 Student/Post Doc presentation and poster Hisham Hamadeh,
award announcements SCCSOT Past-