IMPP 2009 Phy Visit

W
Shared by: HC120729172159
Categories
Tags
-
Stats
views:
2
posted:
7/29/2012
language:
English
pages:
82
Document Sample
scope of work template
							National Immunization Partners’ Program.




    Interamerican College of
     Physicians and Surgeons
                      ICPS
•   Not for Profit (501-C-3)

•   Established in 1979

•   Incorporated in the District of Columbia

•   National Hispanic Medical Society

•   Monthly Medical Journal

•   Monthly Health Awareness Digest

•   Grants - Government and Private
           Major Programs
   Continuing Medical Education
   Academic Detailing
   National Immunization Partner’s Program
   Meetings and Congresses
   National Summit on Health Disparities
   Interamerican Medical Summit
   National Hispanic Academic Network
   National Hispanic Youth Initiative
   Electronic Medical Records
   Physician Recognition Awards
   PBS Series on Minority Health Disparities
   Database and Website Update
   Hispanic Research Network
   Health Link for the Americas
   Know Your Numbers
     Immunization Program
 Continuing Medical Education Program
  sponsored by the Center for Disease Control
  and Prevention (CDC)
 8 hours of category 1 credit toward the AMA
  Physicians Recognition Award™
 Target Population: Hispanic physicians and
  physicians who serve the Hispanic community
      Program Evaluation
 Pre and post-course practice
 questionnaires

 Pre and post-course surveys
    Educational Objectives
 To educate Hispanic physicians and
  physicians who serve the Hispanic
  community about the Immunization
  Partners’ Program
 To improve the participation of Hispanic
  physicians in providing increased
  immunization services for the Hispanic
  community
                  Summary
 Visit- 1 hour
 Independent study - 7 hours
 8 hours of category 1 credit toward the
  AMA Physicians Recognition Award™
 Physicians should claim only the hours
  spend on the program.
                       Topics
   Data and Statistics
   Principles of Vaccination
   General Recommendations on Immunization
   Healthcare Personnel Vaccination Recommendations
   2009 Child & Adolescent Immunization Schedules
   The Vaccine Adverse Event Reporting System
   Catch-up Immunization Schedule for Persons Aged 4 Months
    Through 18 Years Who Start Late or Who Are More Than 1 Month
    Behind—United States • 2009
   Diseases & Vaccines Facts
   Vaccines for Children Program (VFC)
   Vaccine Myths
   Immunization Resources
   Independent Study Material
   Website Recommended to book mark in your Computer
National Estimated Vaccination Coverage
         Immunization Survey




        http://www.cdc.gov/vaccines/stats-surv
         Impact of Influenza
 36,000 influenza-associated pulmonary and
  circulatory deaths occurred during each
  influenza season
 Persons 65 years of age and older account for
  more than 90% of deaths
 More than 200 thousand influenza-related
  hospitalizations per year


  http://www.cdc.gov/flu/weekly/fluactivity.htm
Avian Influenza (H5N1)
 421 human infections with 257 (61%) deaths (WHO April 23, 2009)
 To date, human cases have been reported in six
  countries, most of which are in Asia.
 To date, no infections caused by H5N1 have been
  reported in the United States
 Contact with dead or sick birds is the principal source
  of human infection




        www.who.int/topics/avian_influenza
Swine Influenza (Flu)
 Is a respiratory disease of pigs caused by type A
  influenza viruses that causes regular outbreaks in
  pigs.
 People do not normally get swine flu, but human
  infections can and do happen.
 This new virus was first detected in people in the
  United States in April 2009.
 CDC recommends the use of Oseltamivir or
  Zanamivir for the treatment and/or prevention of
  infection with these swine influenza viruses.
            http://www.cdc.gov/h1n1flu
Principles of Vaccination
 Immunity & the immune system
 Active immunity
 Passive immunity
 Factors may influence the immune response to
  vaccination
 Classification of vaccines
 Live attenuated vaccines
 Inactivated vaccines
         Types of Immunity

                   Active Immunity
 Protection produced by the person's own immune
    system
   Usually permanent
   Another way to produce active immunity is by
    vaccination
                     Passive Immunity
   Protection transferred from another person or animal
   Temporary protection that wanes with time
   Transplacental most important source in infancy
 The Immune system complex
              Antigen
 A live or inactivated substance (e.g., protein,
  polysaccharide) capable of producing an
  immune response
             Antibody
 Protein molecules (immune-globulin)
  produced by B lymphocytes to help
  eliminate an antigen
Factors may influence the immune
     response to vaccination
 Presence of maternal antibody
 Nature and dose of antigen
 Route of administration
 Presence of adjuvant (e.g., aluminum-containing
 materials added to improve the immunogenic of the
 vaccine)
 Host factors such as age, nutritional factors,
 genetics and coexisting disease, may also
 affect the response.
   Classification of Vaccines
 There are two basic types of vaccines:
 live attenuated and inactivated

 Their characteristics are different, and
 these determine how the vaccine is used
Classification of Vaccines
 Live attenuated   Inactive
 1.     Viral      1. Whole
                         - Virus
                           - Bacterial



                   2.   Fractional
 2.    Bacterial
                           - Protein based
                           - Polysaccharide
                             based
  Live attenuated vaccines

 Virus: Measles, Mumps, Rubella, Yellow
 fever, intranasal Influenza, Rotavirus
 and oral Polio (not in US)

 Bacterium: BCG, oral Typhoid.
      Live Attenuated Vaccines
            Characteristic
 The resulting vaccine organism retains the
  ability to replicate and produce immunity,
  but does not cause illness.
 Must replicate to be effective.
 Immune response similar to natural
  infection.
 Usually effective with one dose, except those
  administrated orally.
 Can have interference from circulating
  antibody.
 Must be stored and handled carefully.
      Inactivated vaccines
 Whole                               Fractional
                              1. Protein Based
                                 Toxoid:       Diphtheria
1. Whole viruses:                              Tetanus
               Polio,
               Hepatitis A,      Subunit:      Hepatitis B
               Rabies,                         Influenza A
               Influenza                       Cellular Pertussis
                                               (Lyme), (HPV)
                              2. Polysaccharide based
2. Whole bacteria:
                                  Pure: Pneumococcal
               (Pertussis)              Meningococcal
               (Typhoid)
                                        Salmonella Typhi (VI)
               (Cholera),
               (Plague)       3. Conjugate : H influenzae Type b
                                             Pneumococcal
                                           Meningococcal
Inactivated vaccines Characteristics
  Cannot replicate
  Generally not as effective as live vaccines
  Less interference from circulating antibody than
   live vaccines
  Generally require 3-5 doses
  Immune response mostly humoral
  Antibody titer may diminish with time
Antibody–Vaccine Interactions
 Inactivated vaccines generally are not affected
  by circulating antibody to the antigen
 Live attenuated vaccines may be affected by
  circulating antibody to the antigen.
 When give vaccine first: wait 2 weeks before
  giving antibody
 When give antibody first: wait more than 3
  months before giving antibody vaccine*

*Except rotavirus vaccine, which should be delayed for 6 weeks
Interval between subsequent doses
of the same vaccine
 Increasing the interval between doses of a
  multidose vaccine does not diminish the
  effectiveness of the vaccine.
 Decreasing the interval between doses of a
  multidose vaccine may interfere with antibody
  response and protection.
 Vaccine doses should not be administered at
  intervals less than the recommended
  minimum intervals or earlier than the
  minimum ages.
     The Vaccine Adverse Event
         Reporting System
 The Vaccine Adverse Event Reporting System
  (VAERS) is a national reporting system, jointly
  administered by CDC and FDA.
 For more information go to
  http://vaers.hhs.gov
 Phone at 800-553-6847
 Mail to : VAERS
           P.O. Box 1100
           Rockville, MD 20849-1100
           Contraindications
            and Precautions
   Serious allergic reaction (e.g., anaphylaxis) after a
      previous vaccine dose or to a vaccine component.
     Encephalopathy within 7 days of administration
      of previous dose of DTP or DTaP
     Moderate or severe acute illness with or without
      fever
     Guillain-Barré syndrome <6 weeks after previous
      dose of tetanus toxoid-containing vaccine
     Known severe immunodeficiency

http://www.cdc.gov/vaccines/recs/vac-admin/contraindications-vacc.htm
    Invalid Contraindications
          to Vaccination
 Mild illness
 Antimicrobial therapy
 Disease exposure or convalescence
 Pregnant or immunosuppressed person in
  the household
 Breastfeeding
 Preterm birth
 Allergy to products not present in vaccine or
  allergy that is not anaphylactic
 Family history of adverse events
 Tuberculin skin testing
 Multiple vaccines
Screening Questions
 Is the child (or are you) sick today?
 Does the child have an allergy to any medications,
  food, or any vaccine?
 Has the child had a serious reaction to a vaccine in
  the past?
 Has the child had a seizure, brain or nerve
 problem?
 Does the child have cancer, leukemia, AIDS, or any
  other immune system problem?
 Standardized screening questionnaires are available
  at http://www.immunize.org (bottom-left of webpage)
  Immunization
  Registries
 Single data source for all providers
 Reliable immunization history
 Produce records for patient use
 Key to increasing immunization levels


     http://www.cdc.gov/vaccines/programs/iis
Reminders and recall to Patients
  Reminder- notification that
   immunization is due soon
  Recall- notification that
   immunization are past due
  Content of message and technique of
   delivery vary
  Reminders and recalls have been
   found to be effective
Reminders and recall to Providers

 Communication to healthcare providers that an
  individual client’s immunizations are due soon or
  past due
 Example:
     Computer-generated list
     Stamped note in chart

     Immunization due clip on chart
Reasons for Missed Opportunities

  Lack of simultaneous administration
  Unaware patient needs additional
   vaccines
  Invalid contraindications
  Inappropriate clinic policies
  Reimbursement deficiencies
      Reduction to barriers to
          Immunization

 Physical barriers
     -waiting time
     -distance
 Psychological barriers
     -unpleasant experience
     -safety concerns
      Healthcare Personnel Vaccination
             Recommendations
 Hepatitis B
 Influenza
 MMR
 Varicella
 Chickenpox
 Tetanus, diphtheria, Pertussis.
 Meningococcal


For more info go to http://www.immunize.org
        2009 Child & Adolescent
        Immunization Schedules
 Recommended Immunization Schedule
 for children from birth through 6 Years

 Recommended Immunization Schedule
 for persons aged 7 through 18 Years



     www.cdc.gov/vaccines/recs/schedules/child-schedule.htm
Recommended Immunization Schedule for Persons Aged
               0 Through 6 Years




      www.cdc.gov/vaccines/recs/schedules/child-schedule.htm
Recommended Immunization Schedule for Persons
         Aged 7 Through 18 Years
Catch-up Immunization Schedule for Persons
      Aged 4 Months Through 6 Years
CATCH-UP SCHEDULE FOR PERSONS AGED 7
          THROUGH 18 YEARS
          Diseases & Vaccines Facts
1.    Diphtheria and Diphtheria Toxoid Vaccine
2.    Tetanus and Tetanus Toxoid Vaccine
3.    Pertussis and Pertussis Vaccine
4.    Rotavirus and Rotavirus vaccine
5.    Polio and Polio Vaccine
6.    Haemophilus influenzae type B and Hib Vaccine
7.    Influenza and Influenza vaccine
8.    Measles and Measles Vaccine
9.    Mumps and Mumps Vaccine
10.   Rubella and Rubella Vaccine
11.   Varicella and Varicella Vaccine
12.   Herpes zoster and Single vaccine
13.   Hepatitis A and Hepatitis A Vaccine
14.   Hepatitis B and Hepatitis B Vaccine
15.   Human papilloma virus vaccine and HPV Vaccine
16.   Pneumococcal Disease and Pneumococcal Vaccine
17.   Meningococcal Disease and Meningococcal Vaccine
   Corynebacterium Diphtheriae
         http://www.cdc.gov/vaccines/vpd-vac/diphtheria/default.htm

                                         Membrane may cause Respiratory
•Aerobic gram-positive                            obstruction
bacillus
•This germ produces a
poisonous toxin which
frequently causes heart and
nerve problems
•Insidious onset of exudative
pharyngitis
•Exudates spreads within 2-3
days and may form adherent
membrane
•Fever usually not high but
patient appears toxic
            Clostridium Tetani
          http://www.cdc.gov/vaccines/vpd-vac/tetanus/default.htm

•Anaerobic gram + spore-
forming bacteria

•Generalized tetanus:
descending symptoms of
trismus (lockjaw), difficulty
swallowing, muscle rigidity
and spasms
      Pertussis Pathogenesis
        http://www.cdc.gov/vaccines/vpd-vac/pertussis/default.htm




 Highly contagious respiratory infection caused
  by Bordetella Pertussis
 Attachment to cilia of ciliated epithelial cells
  in respiratory tract
 Local tissue damage in
   respiratory tract
 Systemic disease may
  be toxin mediated
      Vaccine Dtap, Tdap
 DTaP and pediatric DT used through age 6 years
 Tdap Td for person > 7 years
 One dose of DTap, at each of the following ages: 2, 4, 6,
  and 15-18 months and 4-6 years
 A single dose of Tdap is recommended for adolescents
  11 or 12 years of age, or in place of one Td booster in
  older adolescents and adults age 19 through 64
 Td is a tetanus-diphtheria vaccine given to
  adolescents and adults as a booster shot every
   10 years
 Tdap is similar to Td but also protects against
  Pertussis
         Rotavirus Disease
      http://www.cdc.gov/vaccines/vpd-vac/rotavirus/default.htm



In the United States annually responsible for:
 More than 400,000 physician visits
 55,000-70,000 hospitalizations
 More than 200,000
  emergency dept. visits
 20-60 deaths
Rotavirus vaccine (Rota)
 The new rotavirus vaccine is recommended in a
  3-dose schedule at ages of:
    2-4-6 months of age
 Administer the first dose at age 6–12 weeks
 Do not start the series later than age 12 weeks
 Administer the final dose in the series by age 32 weeks
 Do not administer a dose later than age 32 weeks
 Data on safety and efficacy outside of these age ranges
  are insufficient
Poliovirus
http://www.cdc.gov/vaccines/vpd-vac/polio/default.htm

  Entry into mouth
  Enterovirus (RNA)
  Three serotypes: 1, 2, 3
  Replication in pharynx, GI
   tract, local lymphatic
  Hematology spread to
   lymphatic and central
   nervous system
  Viral spread along nerve
   fibers
  Destruction of motor
   neurons
Inactivated Polio Vaccine
 Contains 2-phenoxyethanol, neomycin, streptomycin,
    polymyxin B
   Only IPV is available in the United States
   Schedule begun with OPV should be completed with IPV
   Any combination of 4 doses of IPV and OPV by 5 years
    constitutes a complete series
   Routine vaccination of US residents > 18 years of age not
    necessary or recommended
   May consider vaccination of travelers to polio-endemic
    countries and selected laboratory workers
   Administer at 2-4-6(to 18) months of age with a booster at
    4-6 years of age
                   Haemophilus influenzae type b
                   http://www.cdc.gov/vaccines/vpd-vac/hib

                                                       Severe bacterial infection,
    Epiglottitis                                          particularly among infants
       17%
                                                         Aerobic gram Negative bacteria
                                         Meningitis
                                           50%           Polysaccharide capsule
Pneumonia                                                Six different serotypes (a-f) of
   15%
                                                          polysaccharide capsule
                                                         95% of invasive disease caused
Osteomyelitis
     2%
          Arthritis
                                                          by type b
              8% Cellulitis Bacteremia
                    6%
                                                         Cause 3 million cases of meningitis
                                2%
                                                          and severe pneumonia,
                                                          approximately 386,000 deaths
                                                          worldwide per year in children
                                                          aged <5 years
   Haemophilus influenzae type b Vaccine
            Routine Schedule

 Minimum age: 6 weeks
 • If PRP-OMP (PedvaxHIB® or Comvax®
  [HepB-Hib]) is administered at ages 2 and 4
  months, a dose at age 6 months is not
  indicated.
 • TriHiBit® (DTaP/Hib) should not be used
  for doses at ages 2, 4, or 6 months but can be
  used as the final dose in children aged 12
  months or older.
                   Influenza
       http://www.cdc.gov/vaccines/vpd-vac/flu

                      Who should get vaccinated each year
   Children aged 6 months until their 19th birthday, Pregnant women
   People 50 years of age and older
   People of any age with certain chronic medical conditions
   People who live in nursing homes and other long term care facilities
   Healthcare workers

                        Who Should Not Be Vaccinated
 People who have a severe allergy to chicken eggs
 People who have had a severe reaction to an influenza vaccination in the past
 People who developed Guillain-Barre Syndrome (GBS) within 6 weeks of
  getting an influenza vaccine
 Children less than 6 months of age
 People who have a moderate or severe illness with a fever should wait to get
  vaccinated until their symptoms lessen
Timing of Influenza Vaccine Programs

 Providers should begin offering vaccine soon
  after it becomes available, if possible by
  October
 To avoid missed opportunities for vaccination,
  providers should offer vaccine during routine
  healthcare visits or during hospitalizations
  whenever vaccine is available
   Inactivated Influenza Vaccines (TIV) &
 Live, attenuated influenza vaccine (LAIV)
Minimum age: 6 months for trivalent inactivated influenza
 vaccine [TIV]; 2 years for live, attenuated influenza vaccine
 [LAIV)

 Administer annually to children aged 6 months through 18 years
 For healthy non-pregnant persons: aged 2 through 49 years,
  either LAIV or TIV may be used

 Children receiving TIV should receive 0.25 ml if aged 6 through
  35 months or 0.5 ml if aged 3 years or older

 Administer 2 doses (separated by at least 4 weeks) to children
  aged younger than 9 years who are receiving influenza vaccine
  for the first time or who were vaccinated for the first time during
  the previous influenza season but only received 1 dose
    Measles Clinical Features
        http://www.cdc.gov/vaccines/vpd-vac/measles

 Maculopapular, becomes confluent
 Begins on face and head
 Persists 5-6 days
 Highly contagious viral illness
 Paramyxovirus (RNA)
 Hemagglutinin important surface antigen
 One antigenic type
 Rapidly inactivated by heat and light
Mumps Clinical Features
http://www.cdc.gov/vaccines/vpd-vac/mumps

    Incubation period 14-18 days
    Prodrome of myalgia, malaise
      headache, low-grade fever
    Parotitis in 30%-40%
    Paramyxovirus
    Respiratory transmission of virus
    Replication in nasopharynx and regional
     lymph nodes
    Viremia 12-25 days after exposure with spread
     to tissues
    Multiple tissues infected during viremia
   Rubella Clinical Features
        http://www.cdc.gov/vaccines/vpd-vac/rubella

 Toga virus
 Respiratory transmission
  of virus
 Incubation period 14 days
 Maculopapular rash 14-17
  days after exposure
 Replication in
  nasopharynx and regional
 lymph nodes
Congenital Rubella Syndrome
 Deafness, Cataracts
 Heart defects
 Microcephaly, Mental
    retardation
   May lead to fetal death or
    premature delivery
   Severity of damage to fetus
    depends on gestational age
   Up to 85% of infants affected if
    infected during first trimester
   Most reported rubella in the
    U.S. since the mid-1990s has
    occurred among foreign-born
    Hispanic adult
      Measles, Mumps, Rubella
MMR Vaccine indications :

 First dose to all infants >12 months of age
 Second dose is recommended routinely at age 4-6
  years
 Adult born before 1957 can be considered immune to
  measles
 Adult born during or after 1957 should received >1 dose
 Second dose is for the adult who have recently
  exposed to measles, mump outbreak
       Autism Controversy
                 http://www.cdc.gov/autism


 To date there is no convincing evidence that any vaccine causes
  autism or autism spectrum disorder.
 Concern has been raised about a possible relation between MMR
  vaccine and autism by some parents of children with autism.
 “Removed thimerosal (mercury) from childhood vaccines was done in
  1999, Thimerosal was removed from vaccines due to concerned about
  mercury”. The U.S. Public Health Service and the American Academy
  of Pediatrics called to be removed from vaccines administered to
  young children.
 “The only vaccine we routinely give to young children that still
  contains thimerosal as a preservative is some formulations of
  influenza vaccine”
Decisions of the U.S. Court of Federal Claims in Omnibus Autism
                Proceeding February 12, 2009
    The U.S. Court of Federal Claims divided the claims into
                      three different theories:
   Theory 1: MMR in combination with thimerosal-
    containing vaccines can cause autism.
   Theory 2: Thimerosal-containing vaccines alone can cause
    autism.
   Theory 3: The MMR vaccine alone can cause autism
         Each of the Special Masters ruled that the measles-
     mumps-rubella vaccine, whether administered alone or in
         conjunction with thimerosal-containing vaccines,
  were not causal factors in the development of autism or
                   autism spectrum disorders
Varicella Clinical Features
http://www.cdc.gov/vaccines/vpd-vac/varicella

 Herpes virus (DNA)
 Incubation period 14-16 days
 Generally appear first on head; most concentrated on
    trunk
   Successive crops (2-4 days) of pruritic vesicles
   Primary infection results in varicella (chickenpox)
   Recurrent infection results in herpes zoster (shingles)
   Respiratory transmission of virus
   Replication in nasopharynx and
    regional lymph nodes
      Congenital Varicella Syndrome
 Results from maternal infection during
  pregnancy
 Period of risk may extend through first 20
  weeks of pregnancy
 Low birth weight, atrophy of extremity with
  skin scarring, eye and neurologic
  abnormalities
    Varicella Vaccine-MMRV (ProQuad)
 Combination measles, mumps, rubella and varicella
  vaccine
 Titer of varicella vaccine virus in MMRV is more than 7
  times higher than standard varicella vaccine

                     In Children
 Routine Vaccination at 12-18 months of age
 Recommended for all children without evidence of varicella
  Immunity by 13th birthday
                     Adolescents and adults
 All persons > 13 years of age without evidence of varicella
  Immunity
 Two doses separately by 4-8 weeks
 Do not repeat first dose because of extended interval between
  doses
        Shingles
        http://www.cdc.gov/vaccines/vpd-vac/shingles

 Shingles is a painful skin rash caused by the varicella zoster virus
  (VZV)
 Pain, itching or tingling of the skin which is followed by a painful
  skin rash of blister-like lesions, usually localized to a small area
  on one side of the body
 Anyone who has recovered from chickenpox may develop
  shingles, including children. However, shingles most commonly
  occurs in people 50 years old and older
Hepatitis A Clinical Features
http://www.cdc.gov/vaccines/vpd-vac/hepa

     Picornavirus (RNA)
     Entry into mouth
     Viral replication in the liver
     Virus present in blood and feces 10-12 days
      after infection
     Virus excretion may continue for up to 3
      weeks after onset of symptoms
     Incubation period 28 days
     Children generally asymptomatic, adults
      symptomatic
Recommendation for Routine Hepatitis A
           Vaccination
Adult 1 dose and 1 booster dose 6-18 months after first dose
Children and adolescent 1 dose and 1 booster doses 6-18 months
after first dose
 International travelers
 Men who have sex with men
 Persons who use illegal drugs
 Persons who have clotting-factor disorders
 Persons with occupational risk
 Persons with chronic liver disease

All children should receive hepatitis A vaccine at 12-23 months age
Children who are not vaccinated by 2 years of age can be vaccinated
at subsequent visits
Hepatitis B Virus Infection
http://www.cdc.gov/vaccines/vpd-vac/hepb



 Hepadnaviridae family (DNA)
 >300 million chronically infected worldwide
 Established cause of chronic hepatitis and
  cirrhosis
 Human carcinogen—cause of up to 80% of
  hepatocellular carcinomas
 Hepatitis B Complications

 Fulminant hepatitis
 Hospitalization
 Cirrhosis
 Hepatocellular carcinoma
 Death
   Hepatitis B Perinatal
      Transmission
If mother is positive for HBsAg and HBeAg
   70%-90% of infants infected

   90% of infected infants become
    chronically infected
If positive for HBsAg only
   10% of infants infected

   90% of infected infants become
    chronically infected
            Hepatitis B Vaccine
 Doses at Birth or 1-2 months and 6-18 months with
    interval 4, 4 and 8 wks
   Infants who mothers are HBsAg + or unknown should
    receive the third dose at 6 months of age and least 16
    wks of interval of first
   Dose Routine vaccination recommended through age
    18 years
   Integrate into routine adolescent immunization visit
   Three doses (first one, 1month, 5months)
   Third dose must be separated from first dose by at
    least 16 wks
Human Papiloma Virus associated cancer
              lesions
      www.cdc.gov/cancer/hpv/statistics/
Human Papilloma Virus vaccine
http://www.cdc.gov/std/HPV


  Give the first dose of the HPV vaccine series
   to females at age 11–12 years
  Give the second dose 2 months after the first
   dose
  The third dose 6 months after the first dose
  Give the HPV vaccine series to females at age
   13–18 years if not
   previously vaccinated
Neisseria Meningitidis
    http://www.cdc.gov/vaccines/vpd-vac/mening



 Aerobic gram-negative bacteria
 Severe acute bacterial infection
 Cause of meningitis, sepsis, and focal infections
 Abrupt onset of fever, meningeal symptoms,
  hypotension and rash
 Fatality rate 9%-12%; up to 40% in meningococcemia
 At least 13 Sero groups based on characteristics of the
  polysaccharide capsule
 Most invasive disease caused by sero groups A, B, C, Y,
  and W-135
  Meningococcal vaccine
 http://www.cdc.gov/vaccines/vpd-vac/mening


Meningococcal Polysaccharide Vaccine (MPSV)
 Quadrivalent polysaccharide vaccine (A, C, Y, W-135)
 Approved for persons 2 years of age and older
 Administered by subcutaneous injection


Meningococcal Conjugate Vaccine (MCV)
 Quadrivalent polysaccharide vaccine (A, C, Y, W-135)
 Conjugated to diphtheria toxoid
 Approved for persons 11 through 55 years of age
 Administered by intramuscular injection
    Streptococcus Pneumoniae
    http://www.cdc.gov/vaccines/vpd-vac/pneumo


 Gram-positive bacteria
 More than 80 serotypes described by 1940
 First U.S. vaccine in 1977
 90 known serotypes
 Polysaccharide capsule important virulence
  factor
 Pneumococcal Pneumonia, Bacteremia,
  Meningitis
Pneumococcal Meningitis
    Estimated 3,000 - 6,000 cases per year
     in the United States
    Case-fatality rate ~30%, up to 80% in
     the elderly
    Neurologic sequelae common among
     survivors
    Children at Increased Risk of Invasive
             Pneumococcal Disease
    Functional or anatomic asplenia,
     especially sickle cell disease
    HIV infection
    Alaska Native, African-American,
     American-Indian
    Child care attendance
         Pneumococcal
         Vaccine
   Recommended for all children less than 24 months old
   For children between 24 and 59 months old who are at high risk of disease
   Older children and adults with risk factors
   Alaskan Native or from certain Native American populations may receive the
    Pneumococcal polysaccharide vaccine, (Pneumovax® and Pnu-Immune®).

Revaccination with pneumococcal polysaccharide vaccine:
 One-time revaccination after 5 years for persons with:
   -Chronic renal failure or nephrotic syndrome;
   -Functional or anatomic asplenia
   -Immunosuppressive conditions.
 For persons aged >65 years, one-time revaccination if they were vaccinated >5
  years previously and were aged <65 years at the time
Vaccines for Children Program
http://www.cdc.gov/vaccines/programs/vfc/contacts-state.htm


• VFC helps families of children who may not
  otherwise have access to vaccines by providing
  free vaccines to doctors who serve them.

• Any provider authorized to prescribe vaccines
  under your state law can be a VFC Provider. .

• VFC is administered at the national level by
 the CDC contracts with vaccine manufacturers
 to buy vaccines at reduced rates.
    Common Vaccine Questions
 Is it okay for my baby to have so many shots at once?
 Don’t infants have natural immunity?
 Haven’t we gotten rid of most of these diseases in this
    country?
   I heard that some vaccines can cause autism. Is this
    true?
   Can’t I just wait until my child goes to school to catch
    up on immunizations?
   Why does my child need a chickenpox shot? Isn’t it a
    mild disease?
   My child is sick right now. Is it okay for her to still get
    shots?
   Where can I get more information?
 Independent Study Material
 Epidemiology and Prevention of Vaccine-
 Preventable Disease, The Pink Book, 11Th edition,
 National Immunization Program

 http://www.cdc.gov/vaccines/pubs/pinkbook
 Chapters 1 through 20
 Appendices A through H
              Websites to bookmark

 www.cdc.gov/mmwr/PDF/wk/mm5753-Immunization.pdf

 www.cdc.gov/vaccines/pubs/pinkbook/pink-slides.htm

 www.cdc.gov/vaccines

 www.cdc.gov/vaccinesafety

 www.cdc.gov/vaccines/programs/vfc/default.htm

 www.icps.org/index/article_list.php?type=son&id=40
For more Information
Contact the National
Immunization Program (NIP):

E-mail    NIPInfo@cdc.gov
Hotline   1-800-CDC-INFO
Website   www.cdc.gov/nip

						
Related docs
Other docs by HC120729172159
ROSTER CONTRACT FALL
Views: 1  |  Downloads: 0
What I�mn reading now
Views: 0  |  Downloads: 0
SPPD Recruiting Guide
Views: 2  |  Downloads: 0
Creates a legal pleading
Views: 0  |  Downloads: 0
100512CCMO
Views: 0  |  Downloads: 0
Rotational Grazing Calculators (Excel)
Views: 3  |  Downloads: 0
Caldwell College � Education Department
Views: 0  |  Downloads: 0
Exposure Control Plan
Views: 1  |  Downloads: 0
2012-2013 School Calendar - DOC
Views: 2  |  Downloads: 0