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							                      Reference No: KIN-HIT/BIC/R 1/2011




       TENDER DOCUMENT
                         FOR

          SUPPLY, INSTALLATION, TESTING

 COMMISSIONING , DEMONSTRATION AND TRAINING

                          OF

     EQUIPMENTS / INSTRUMENTS / APPARATUS

                         FOR

       BIOTECHNOLOGY INCUBATION CENTRE

                          AT

       KINFRA HI -TECH PARK, KALAMASSERY


                       Volume- 1

                   TECHNICAL BID


      Issued to: ………………………………….



Kerala Industrial Infrastructure Development Corporation
‘Sreepadam’, T.C. No. 31/2312, Sasthamangalam P.O.
 Trivandrum - 695 010, Ph: 0471 - 2726585, 2724773(F)
 Website: www.kinfra.org E-mail: kinfrapark@gmail.com



                                                           1
                                       TENDER IN BRIEF

Kerala Industrial Infrastructure Development Corporation (KINFRA), a statutory body of
Govt. of Kerala, is setting up a Biotechnology Incubation Centre at its Biotech Zone in
Kalamassery, Ernakulam District. Sealed offers are invited from reputed manufacturers
or bonafide Indian agents/Indian Suppliers who have all India network of Sales and
Service either directly or through their authorized dealers / distributors for supply,
installation, testing, commissioning, demonstration and training of the following
equipments / instruments.
                                      TABLE 1.

                                                                         Tender             Avg annual
                                                             Issue of
                                                   Quanti                 Cost              Turn over
 Refer. No      Tender No      Name of equipment              Tender
                                                     ty                            EMD        In lakhs
                                                            document       (`)
                                                                                    (`)

             BIC/RB1/01/2011    Genetic Analyser     1
                                                                          10000    250000          150
                                     Liquid
             BIC/RB2/02/2011    Chromatograph-       1                    10000    250000          150
                                    MS MS
                                 Refrigerated
             BIC/RC1/03/2011   Centrifuge (Floor     1                      5000   100000           60
                                    model)
                                  Real Time-
   KIN-                                                     26.12.2011
             BIC/RB8/04/2011   Polymerase Chain      2                      4500   90000            60
 HIT/BIC/                                                       To
                                    Reactor
 R 1/2011                                                   10.01.2012
                               Rotary Evaporator
             BIC/RC9/05/2011                         1
                                        II                                  4000   75000            45
             BIC/RC6/06/2011    Fermenter 20 Lit     1
                                                                            3500   75000            40
             BIC/RC5/07/2011    Fermenter 7 Lit      1                      2100
                                                                                   35000            20
                                    Liquid
             BIC/RB6/08/2011                         1                      1600   26000            20
                                Chromatography




Eligibility Criteria:

    1. The bidder should have a minimum average annual turnover as in Table no.1
       during the last 3 financial years. Documentary proof of turnover in Indian Rupees
       (certified by Chartered Accountant in India or approved competent authority in
       case of foreign supplier) to be provided.

    2. The bidder should not have incurred any loss during the last three financial years.

    3. The bidder should have supplied, installed and commissioned these equipments
       at least in three reputed Indian organizations (Research / Laboratory / Institute of
       the State / Central Government Departments / Undertakings / Large Private
       Concerns) in the past 3 years.




                                                                                                    2
Tender documents can be downloaded from the website www.kinfra.org or obtained
during office hours on all working days (between 9.30am to 5:00 p.m.) from the Park
Centre, KINFRA Hi-Tech Park, Opposite Co-operative Medical College, Kalamassery-
683503 by paying cost as mentioned in Table no:1 in the form of cash/ demand draft
drawn in favour of Managing Director KINFRA payable at Thiruvanathapuram. Those
who download the form from website should submit the fees in the form of Demand
Draft along with Technical bid. Tender documents are not transferable.

Foreign bidders may obtain the tender documents through their authorized Indian
agents.

The EMD as in Table no.1 should be in the form of demand draft/ Bank Guarantee from
a scheduled bank/ Nationalized bank infavour of The Managing Director, KINFRA,
payable at Trivandrum. Separate EMD to be submitted in case the bidder is quoting for
more than one item .

Tenders submitted through e-mail or fax will not be considered. KINFRA is not liable for
non-receipt, delay or loss of document when sent / received by post or courier. Bids to be
submitted in separate envelopes in case the bidder is quoting for more than one item.
Tenders received without EMD will not be considered at all. KINFRA reserves the right
to accept or reject any or all tenders without assigning any reasons whatsoever and no
claim shall be made by any supplier as a matter of right.


The time and date of opening of Price Bid (envelop- 2) of the tender shall be intimated
only to the qualified bidders at a later date.

       Date of issue of tender document      :   26.12.2011 to 10.01.2012
       Date of Prebid meeting                :   05.01.2012 (11.00 am)
       Last Date of Submission               :   11.01.2012 (2.00 pm)
       Date of opening of Technical Bid      :    11.01.2012 (2.30 pm)




Thiruvananthapuram                                                               Sd/
Date: -                                                            Managing Director




                                                                                        3
INSTRUCTION TO BIDDERS

The details regarding specifications of Equipments are given as Annexure I to
VIII. The tender / offer should give the following information:

1. Eligibility Criteria:

   1   The bidder should have a minimum average annual turnover (from sales) as
       in Table no 1 during the last 3 financial years. Documentary proof of
       turnover(certified by Chartered Accountant in India or approved competent
       authority in case of foreign supplier) to be provided.

   2 The bidder should not have incurred any loss during the last three financial
     years.

   3 The bidder should have supplied, installed and commissioned similar
     equipments at least to three reputed Indian organizations (Research /
     Laboratory / Institute of the State / Central Government Departments /
     Undertakings / Large Private Concerns) in the past 3 years.

2. Instructions for submission of Tender

The bids for these equipments shall be in two parts viz. Envelope- I with
Technical Bid and envelop II with Price bid respectively. Both sealed envelops
should be kept in another envelope and should be addressed to The Manager
(Technical), KINFRA Hitech Park, Opp.Medical College, HMT Colony .P.O,
Kalamassery, Kochi-683 503, super scribed “Tender Documents for the Supply of
Equipment for Biotechnology Incubation Centre at Kinfra Hitech Park (Tender
No:................” so as to reach the Manager (Technical) on or before 2.00 p.m
11.01.2012 (For Tender no., Please refer to Table No 1).

3. a. Part I – TECHNICAL BID

Technical bid shall contain:

       1. Earnest Money Deposit (EMD) as specified in the Table no.1, must be
          sent along with the offer, otherwise the offer will not be considered at
          all. The EMD should be in the form of demand draft/ Bank Guarantee
          from a scheduled bank/ Nationalized bank in favour of The Managing
          Director, KINFRA, payable at Trivandrum. Format of the bank
          Guarantee is attached as Annexure IX. The Earnest Money Deposit of
          un successful bidders will be returned after finalization of the order. The
          earnest Money Deposit of the successful bidder shall be forfeited for the


                                                                                   4
   non-execution of the Order within the delivery period. The EMD of the
   successful bidder will be released only after satisfactory installation and
   commissioning, of the equipments / instruments as per the tender
   document without any interest.

2. List of reputed Indian organizations (Research / Laboratory / Institute of
   the State / Central Government Departments / Undertakings / Large
   Private Concerns) where bidder has supplied the equipments in the past
   3 years, with the following details:

        Capacity & model of the equipment supplied
        Complete postal address of the parties with telephone number;
         fax number, e-mail address to whom equipments have been
         supplied.
        Order number and date together with prices eventually or finally
         paid.
        The name and designation, phone number, email address of the
         contact person there.

3. Satisfactory performance report or Reference letters (current dated)
   from three reputed Indian Organizations (research laboratory, institute
   of the state / central Govt. Departments / undertakings / large private
   concerns) where the equipment was installed, supplied and
   commissioned in last three years.

4. As Proof of annual turnover for the last three financial years, attested
   copies of audited balance sheet and P & L statement should be
   submitted.

5. The bidder has to submit a compliance statement with respect to the
   technical specification along with supporting documents.

6. Detailed specifications, brochures, catalogues, technical literature and
   operation / maintenance manuals of the proposed equipment with salient
   features including model number and capacity. The medium of language
   shall be only English.

7. In case the tender / quotation is submitted by an Indian agent, a letter of
   authority (latest) from the Principal must be enclosed along with the
   offer indicating clearly that the Indian Agent is authorized to quote on
   behalf of the Foreign Principal (applicable to Indian Agents).




                                                                            5
8. Details of services to be rendered by the Principal. (Applicable to Indian
   Agent / Supplier).

9. Details of services to be rendered by the Indian Agent (applicable to
   Foreign Suppliers). Indicate the name and address of Indian Agent.
   Concurrence of the agent also should be attached. Please also indicate
   the amount of Agency Commission payable to Indian Agent in Indian
   Currency after the receipt of the consignment in good condition at our
   Stores and after the satisfactory installation and commissioning at our
   site etc. Foreign Exchange Management Act does not permit the
   inclusion of Indian Agency commission, discount or like rebates
   allowed by Foreign Suppliers in FOB value, payable to their Indian
   Agents. Such commission, discount etc. if any, must be indicated
   separately in the offer. (Applicable to Foreign Suppliers).

10. An undertaking from the bidder (in case if Indian supplier an
   undertaking from the manufacturer) that spares for the supplied
   equipments will be made available for a period of 10 years from the date
   of commissioning. The supply of spares is to be guaranteed at least for a
   period of 10 years after the supply of the equipment.

11. Tender document dually signed and sealed on all pages. Unsigned bid
    will be rejected.

12. The approximate dimensions & weight of the packed consignment such
    as.
         Dimensions
         Tare Weight
         Net Weight

13. Tender fees in the form of demand draft drawn in favour of Managing
   Director, KINFRA payable at Trivandrum shall be enclosed in case
   where tender form has been downloaded from website.

14. All equipment related accessories and consumables are to be specified
    with complete technical details (for eg. Accessories like computer,
    UPS, compressor etc., and consumables like chemicals, high purity
    gases etc.) The make / brand, name and address of the manufactures of
    accessories and consumables are also to be provided. The bidder should
    ensure that all items required for the full performance of the equipment
    are included in the offer. KINFRA shall not be arranging any item,
    whatsoever separately.



                                                                           6
   3.b. Other terms and conditions

   1. Details of (pre installation requirement) related to utilities required for
       the equipment and its accessories are to be clearly specified. (Utilities
       like power (number and type of sockets, electrical rating, earthing etc),
       plumbing, drainage, compressed air, steam, gases etc.) Requirements
       such as the physical space, work table area; environmental conditions
       (eg: air conditioned), foundation/ footings etc. are to be clearly
       specified. Heat emission from the equipments in terms of KW or BTU
       is to be mentioned. All electrical wiring are to be concealed and the
       drawings to be submitted.

   2. Certificate of calibration and inspection are included in the scope of
       supply of equipment wherever applicable. This would include IQ
       (Installation qualification) OQ (Operation Qualification) and PQ
       (Performance Qualification).

   3. No commercial information, which may have financial implications,
       should be mentioned in the Technical bid.

4.a Part II PRICE BID

The Bidder’s offer shall contain:

 1. FOB value, in case of the quotes in foreign currency including packing,
    forwarding and inland freight charges. Where quotes are in Indian rupees,
    the offer must be free delivery at KINFRA Hi Tech, Opp Co Op, Medical
    College, Kalamassery, Ernakulam district.

 2. CIF (Kochi) value by airfreight. Freight quoted must be on IATA basis
    either on volume or weight basis, in case of foreign suppliers.

 3. Percentage & amount of Indian agency commission, payable to Indian
    agent in Indian currency, after the receipt of consignment in good
    condition at our Stores & after satisfactory installation and
    commissioning etc. (applicable to Indian Agent).

 4. FOB rates must be given for any of the following Gateway International
    Airports. Specify the gateway International Airport.

COUNTRY                       GATEWAY INTERNATIONAL AIRPORT
Germany                       Frankfurt
Japan                         Tokyo


                                                                               7
  Hongkong                       Hongkong
  UK                             London
  USA                            New York
  Switzerland                    Zurich / Geneva
  Singapore                      Singapore (Changi Airport)
  Australia                      Sydney
  Austria                        Vienna
  Belgium                        Brussels
  Denmark                        Copenhagen
  Netherlands                    Amsterdam
  Canada                         Toronto
  Italy                          Rome / Milan
  France                         Paris
  Korea                          Seoul

5. Rates for all equipment related accessories and consumables if applicable( for
   eg. Accessories like computer UPS, compressor etc. and consumables like
   chemicals, high purity gases etc). The rates quoted for locally supplied items
   should be inclusive of all taxes, VAT, duties, etc, and must be free delivery at
   site. The rates quoted also should include installation, and commissioning of
   such accessories wherever applicable. Such installations and commissioning
   would fully come under scope of supply of equipment.

4.b Other terms and conditions

1 In case of foreign bidders, KINFRA prefers to release the payment on BILL
  basis (excluding Indian Agency Commission) after the receipt of the
  consignment in good condition. Alternatively, depending upon the value and
  foreign exchange regulations the payment can also be considered through Sight
  Draft / Letter of Credit through the State bank of India, Trivandrum, Main
  branch for the order value excluding the Indian Agency Commission.

2. IN CASE OF PAYMENT BY SIGHT DRAFT / LETTER OF CREDIT: 90%
    payment shall be made by Sight Draft / an Irrevocable Letter of Credit
    established in favour of the supplier through State Bank of India, Trivandrum,
    Main branch, Kerala, India” for the order value, excluding the Agency
    Commission due to the Indian Agents, against presentation of original shipping
    documents in case of foreign suppliers. Balance 10% will be released after
    completion of installation and on receipt of Bank Guarantee of 10% of total
    FOB value either from Principal or from their Indian Agent towards
    performance security to be valid for one year from the date of installation.
    Bank guarantee only from Indian nationalized banks will be accepted and in


                                                                                 8
   case a foreign Bank issues Bank Guarantee the correspondent Indian
   nationalized bank should counter sign the same. However, L/C will be opened
   for the full amount. No other payment term will be acceptable to us.

    In case of Indian suppliers (who has quoted in Indian rupees) payment will be
   effected through DD/ cheques only after receipt of equipments / apparatus in
   good condition and successful commissioning. Payment shall be released as
   indicated below:

    a. 70% payment will be made against the submission of delivery challan by
        the supplying firm duly signed and certified by the authorized
        representative of KINFRA.
    b. 20% of the payment will be made after the issue of installation and
        commissioning certificate.
    c. The remaining 10% of the payment will be released after validation of the
        equipment and training to the personnel and on receipt of Bank Guarantee
        towards performance security to be valid for one year from the date of
        installation .
3. All foreign bank charges shall be borne by the supplier / bidder.

4. As far as possible offer should be submitted against airfreight only in case of
   Foreign suppliers.

5. All taxes, duties, levies of any kind payable up to the stage of putting the
   Equipment in FOB position shall be borne by the foreign supplier / bidder.

6. The bidder has to ensure that the price quoted is only as per the technical
   specifications given in the tender schedule.

7. In cases where the quotes are in Indian Rupees, the rates quoted by the bidder
   should be inclusive of all taxes / VAT / duties, levies of all kind, clearing and
   forwarding charges. The expenses related to unloading of material at the site
   and all other handling expenses will be the responsibility of the bidder.
   Charges for packing & forwarding, clearing, insurance, warehouse to ware
   house transit cum erection policy till the equipments are installed,
   commissioned will be to the account of the supplier.

8. The offer should be inclusive of installation, commissioning, testing and
   training/ demonstration charges. The offer must be inclusive of packing and
   forwarding charges.

9. Spares required for three years shall be indicated with prices as an optional
   item. Such prices should not be included in the quote for the equipment.


                                                                                     9
10. Deduction towards Works Contract Tax or any other tax if applicable will be
    made while making payment.
11. Rates quoted for all items should be firm and no escalation of rates will be
    allowed under any circumstances.

5.     General Conditions of Contract.


     1. Enquiries related to this tender should reach KINFRA by email/courier at
        least two days before the scheduled Pre-bid meeting.

     2. Technical Bids will be opened at 2.30 pm 0n 11.01.2012 at Park centre
        Hitech Park, Kalamassery. Price Bids will be opened only of those bidders
        whose Technical Bids are found acceptable by us. The date and time of
        opening for Price bids will be communicated to the successful bidders after
        evaluation of the Technical Bids.

     3. Separate Tender Form should be submitted in separate envelops, in case of
        bidder who is quoting for more than one item of equipment. For each tender
        from kindly specify the tender number as given in Table no 1.

     4. Non-execution of the Order will debar the bidder from any future purchase
        /inquiry from KINFRA.

     5. Rates and other specifications given in the tender must be clearly written,
        or typed, without any correction, cutting or overwriting.

     6. Any other condition written or printed in the tender or otherwise send along
        with the tender shall not be binding on us.

     7. Tenders sent through fax / e- mail will not be considered.

     8. The tenders are liable to be rejected if any of the above conditions are not
        complied with.

     9. Part shipment will not be allowed.

     10. The offer should be valid for 90 days from the date of opening of the
         tender.

     11. Quotations received late / after due date is liable to be rejected summarily.



                                                                                     10
     12. Tender can be rejected if at any stage of the procurement process, it comes
         to knowledge that any tenderer is involved in any fraudulent practice or
         misrepresentation of the facts or tried to influence the selection process or
         indulged in any corrupt activities in competing with others.

     13. It is further to be agreed by both the parties that all differences and disputes
         if not resolved as above, shall be got remedied through the Court of Law of
         Thiruvanathapuram jurisdiction only.

     14. KINFRA reserves the right to accept any tender in full or in part or to reject
         the lowest or any or all tenders without assigning any reason.

     15. KINFRA reserves the right to award the tender either in part or full or
         follow any other suitable procurement procedure. KINFRA at its sole
         discretion and without assigning any reason thereof, reserves the right to
         accept / reject any or all bids at any stage of the tender process.

6.      SPECIAL TERMS AND CONDITIONS


     Delivery

     1. Specific mention should be made for the exact duration required for delivery
         after receipt of the order. The delivery period will have to be     strictly
         adhered to, in case an order is placed against the offer.

     2. The approved firm shall supply the ordered equipment as per terms and
        conditions within the stipulated time indicated in the Intent letter / Purchase
        Order.

     Installation, Testing,  Commissioning,              Trial     run,     Validation,
     Demonstration & Training
     3. The period stipulated for completion of installation, testing,
        commissioning, trial runs, validation, demonstration and training of
        personnel shall be four weeks from the date of delivery of equipment at
        site.
     4. All tools, equipment and machinery required for the installation and
        commissioning work has to be arranged by the successful bidder only.

     5. Complete demonstration of equipments to be given by the successful
        bidder.




                                                                                      11
6. Training of staff for the purchased equipment is to be included in the scope
   of supply of equipment.

Completion

7. Completion Certificate will be issued by the authorized representative of
   KINFRA and countersigned by technical consultant after complete
   validation and training to the personnel handling the equipment.

8. WARRANTY: the equipments supplied must be covered with warranty for
   minimum of 24 months from the date of commissioning against any
   defective manufacture/workmanship etc. Repairs/ replacements/ servicing
   shall be attended free of cost within the warranty period. Bidder shall be
   responsible for after sales service during the warranty period of equipment.
   The after sales services to be rendered by the bidder during warranty and
   there after should be made clear in the tender. The after sales service is an
   essential requirement for supply of equipment.

9. During the guarantee period or later whenever the firm is called upon to
   attend to the rectification of the defects/ faults in the consignment, the firm
   shall attend to the repair work within a week. They should render timely
   back up service whenever called upon. A certificate to the effect should be
   attached to the tender.

10. Software upgrades are to be provided free of cost during and after
   Warranty – where applicable.

11. Inspection certificates of the instruments / equipment inspected by the
   qualified engineer of the manufacturer and packed in accordance with the
   terms and conditions of this order must be enclosed.

Other terms and conditions

14.All the supplies should comply with International & local standards and
   necessary documents / proof to be submitted.
15. Quality Materials should be used for fabrication. All the Material test
    certificates should be supplied along with delivery.
16. The firm shall provide detailed operational and maintenance manuals at the
    time of supply of the equipment.

17. The make / brand and name and address of the manufacturer, country of
    origin, country of shipment and currency in which rates are quoted are to be
    mentioned.


                                                                               12
   18. Any additional features of the equipment quoted shall be mentioned
       separately .




7. SPECIFICATIONS: - *
(* Bidders quoting for a particular equipment can attach corresponding Annexure with
Technical bid.)
Annexure I
                                                       Tender No: BIC/RB1/01/2011
Project                             KINFRA Biotechnology Incubation Centre
Location                            KINFRA Hi-tech Park, Kalamassery
Facility Name                       Molecular Biology Facility
Equipment name                      Genetic Analyzer
Quantity                            One complete system




                                                                                 13
Genetic Analyzer
 Specifications
 1       Components          Capillary Electrophoresis System for Genotyping and
                             DNA analysis

                                    Suitable for various types of DNA sequencing
                                    and analysis like Micro satellite analysis, AFLP,
                                     LOH analysis etc
                                    Fully automatic - Sample loading, Gel loading and
                                     other operations
                                    Sample injection - Electro kinetic or pressure mode
                                    Capable of accommodating sample vials of varying
                                     capacities
                                    Auto sampler capacity -96 samples
                                    Provision for real time data quality evaluation
                                    Power supply unit suitable for fast and efficient
                                     operation

 2       Capillary system
                                   Multi capillary system, Minimum of 8 capillaries
                                   Laser induced Fluorescence based detection
                                   Provision for multiple dye detection in a single
                                    capillary
                                   System must be provided with CCD detection
                                    technology
 3       Active
         temperature               Temperature range : From ambient - 600C
         control        of         Provision for real time data quality evaluation
         capillaries


 4       Computer system           Computer system with accessories
                                   Software for Instrument control, data acquisition
                                    and analysis -Comparative sequencing, mutation
                                    detection, detection of heterozygote insertion and
                                    deletion, etc

 5       Reagents                  All essential accessories and consumables for start
                                    up (Including capillary columns and special
                                    reagents etc.)
                                   Reagents and consumables for DNA sequencing and
                                    genotyping applications (Optional)



                                                                                      14
General Terms & Conditions:

   1. Documentation in Triplicate on receipt of P.O.
   2. G.A. Drawing, Foundation/Footing Drawing.
   3. Machine Drawing for Approval.
   4. Wiring Diagram
   5. Fabrication / Machine “As built drawings”.
   6. Stage wise inspection reports.
   7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
   8. Running Trial Report.
   9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
   10. Performance / Guarantee Certificates.
   11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
   12. Installation, operation & maintenance Manual.
   13. All M.O.C. Certificates.
   14. Name plate details.
   15. Critical spares for two-year operation.
   16. All product contact parts SS 316 L.
   17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
       meter.
   18. Other surfaces Matt Finished.




                                                                                     15
Annexure.II
                                                    Tender No: BIC/RB2/02/2011
Project                            KINFRA Biotechnology Incubation Centre
Location                           KINFRA Hi-tech Park, Kalamassery
Facility Name                      Central Instrumentation Facility

Equipment name                     Liquid Chromatography – MSMS
Quantity                           One complete system


 Liquid Chromatography-MSMS System with all essential accessories and
 software for qualitative and quantitative analysis of small and medium molecules
  Specifications

  1    Sample inlet and        Supported LC flow rate : 5µl to 2 ml
       Interface               Simple and easy to clean interface, suitable for
                               complex matrices
                               Suitably designed to minimise matrix interferences
                               Easy access to customer serviceable parts
                               Effective solvent venting to prevent contamination
                               Solvent compatibility – 100% aqueous to 100
                               organic
  2    Ionization sources      Electrospray (ESI), Atmospheric pressure chemical
                               ionization (APCI)
                               Dual ionization system(Optional)
                               Easy changing of the source without the use of
                               sophisticated tools
                               Easy cleaning the source without venting the
                               system.
  3    Collision cell          High performance collision cell
                               Designed for high scan speeds with high sensitivity
                               and eliminating inter channel cross-talk to enable
                               multiple MRM transitions studies and other
                               advanced modes
                               Optimized for qualitative and quantitative analyses.
  4    Mass analyser           Optimized for analysis of unknown molecules as
                               well as quantitative determinations

  5    Mass range              Lower m/z 10
                               Upper m/z 2000
  6    Mass Resolution         0.3u (FWHM) for the entire mass range

  7    Mass stability          Mass stability of 0.1 amu over 8 hrs under normal
                               operating conditions




                                                                                      16
8    Linear Dynamic Range   Wide linear dynamic range
                            6 orders of magnitude
9    Scan Speed              4000 amu/sec
10   Scan modes             The instrument should be capable of performing
                            Full scan, Selected ion scan, Precursor ion scan
                            MRM.
                            Advanced scan modes for very high MSMS
                            sensitivity, separation of multiply charged species,
                            and to obtain high quality, quantitative and
                            qualitative information from the same run
11   Sensitivity            Should have high sensitivity for quantitative and
                            qualitative analyses

                            MRM mode: S/N (Peak to Peak) 50:1 in ESI +ve
                            mode for 0.5pg of reserpine on column

12   Detector               Should be of high sensitivity and linear dynamic
                            range. And capable of fast polarity switching,
                            Electron multiplier type.

13   Ion Detection          Positive and Negative ions
                            Capable of detection of +ve and –ve ions in the
                            same run
14   Pump System            Should have differential pumped vacuum system
                            using air-cooled turbo molecular pumps, with
                            backing pump or similar high effiency vaccum
                            system. Safe shutdown in case of power failure.

15   Operating Software     Easy to use software
                            Completely automated quantitative and qualitative
                            data processing capability.
                            Automated mass calibration and optimization of
                            operating parameters.
                            Customizable data processing facility.
                            Library generation and search facility.
                            Monitoring only specific transitions based on
                            expected retention times for increased sensitivity.

                            Complete instrument control including the LC
16   HPLC
     Solvent delivery       Quaternary system with gradient mixer
                            Online degasser
                            Pulse-free solvent delivery
     Operating pressure     Up to 6000 psi
     Flow rate              0.1 to 5.0 ml, programmable
     Flow accuracy          +/- 0.5 % RSD


                                                                                   17
      Flow precision              +/- 0.5 % RSD
      Gradient precision          +/- 0.5 %
      Column oven                 Capable of accommodating column of 25 cm length
                                  Oven heating – up to 60 OC- programmable
                                  Temperature accuracy: ± 1oC over entire range.
                                  Temperature stability : ± 0.2 %
                                  Temperature ramp: up to 5 oC / min
 17   Auto sampler
      Injection range             0.5 to 100 micro litter
      Precision                   ≤0.25 % RSD
      Sample capacity             50 vials
      Composition accuracy         0.5 % or better
      Sample carry over           ≤ 0.05 %, Needle rinse- internal as well as external
 18   Accessories like gas
      generator, computer,        A suitable Nitrogen Generator
      printer LC column and
      other essential items for
      start up




General Terms & Conditions:

 1. Documentation in Triplicate on receipt of P.O.
 2. G.A. Drawing, Foundation/Footing Drawing.
 3. Machine Drawing for Approval.
 4. Wiring Diagram
 5. Fabrication / Machine “As built drawings”.
 6. Stage wise inspection reports.
 7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
 8. Running Trial Report.
 9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
 10. Performance / Guarantee Certificates.
 11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
 12. Installation, operation & maintenance Manual.
 13. All M.O.C. Certificates.
 14. Name plate details.
 15. Critical spares for two-year operation.
 16. All product contact parts SS 316 L.
 17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
     meter.
 18. Other surfaces Matt Finished.




                                                                                         18
Annexure III
                                                            Tender No: BIC/RC2/03/2011
Project                               KINFRA Biotechnology Incubation Centre
Location                              KINFRA Hi-tech Park, Kalamassery
Facility Name                         Central Instrumentation Facility-1

Equipment name                        Refrigerated centrifuge (floor model)
Quantity                              Two complete system

Refrigerated Centrifuge (Floor Model)
Specifications

 1     Speed                              20000
 2     Capacity                           4x750 ml
 3     Drive                              Direct, brushless induction
 4     Temperature range                  -5°C to ambient temperature
 5     Rotors                             Fixed angle
                                          Swinging bucket
 6     Refrigerant                        Environment friendly
 7     Noise                              Low noise
 8     Controls                           Microprocessor controlled
                                          Digital setting and display of parameters
                                          Programmable with programme memory
 9     Safety features                    Rotor imbalance detection
                                          Automatic rotor detection, etc.
 10    Interior                           Stainless steel
                                          Convenient for easy cleaning
 11    Essential spares and accessories   Minimum 3 nos rotors has to be provided.
                                          List of suitable rotors also bas to be provided




General Terms & Conditions:

 1.   Documentation in Triplicate on receipt of P.O.
 2.   G.A. Drawing, Foundation/Footing Drawing.
 3.   Machine Drawing for Approval.
 4.   Wiring Diagram
 5.   Fabrication / Machine “As built drawings”.
 6.   Stage wise inspection reports.
 7.   Certificate for Flame Proof Motor limits, Switches, Panel, etc.
 8.   Running Trial Report.
 9.   All brought out items catalogue, operation, maintenance- Manual & Certificates.


                                                                                        19
10. Performance / Guarantee Certificates.
11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
12. Installation, operation & maintenance Manual.
13. All M.O.C. Certificates.
14. Name plate details.
15. Critical spares for two-year operation.
16. All product contact parts SS 316 L.
17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
    meter.
18. Other surfaces Matt Finished.




                                                                                  20
Annexure IV
                                                             Tender No: BIC/RB8/04/2011
Project                                KINFRA Biotechnology Incubation Centre
Location                               KINFRA Hi-tech Park, Kalamassery
Facility Name                          Molecular Biology

Real Time PCR
One complete system
Specification

(i)           0.1ml/0.2ml 96-well plate or 12 x 0.1ml/ 0.2ml 8-tube strip sample format

(ii)          10-50 µl sample volume

(iii)         4-5oC ramp rate

(iv)          4oC to 100oC temperature range

(v)           0.25oC or better temperature accuracy

(vi)          0.5 oC or better well to well to uniformity

(vii)         Thermal gradient facility for the optimization of the annealing
              temperatures
(viii)
              3-5 colour detection

(ix)
              Open chemistry and multichannel detection suitable for multiplexing with
              minimum cross talk
(x)
              Calibration free operation without a passive reference dye
(xi)
              Suitable software for: relative quantification, multiple endogenous
              control standardization, efficiency correction, melt-curve analysis, multi-
              plate analysis


Desirable     Suitable softwares for downstream analysis of large data sets


Accessories          Suitable Computer with an operating system compatible with the
                      RT-PCR software



                                                                                            21
General Terms & Conditions:

   1. Documentation in Triplicate on receipt of P.O.
   2. G.A. Drawing, Foundation/Footing Drawing.
   3. Machine Drawing for Approval.
   4. Wiring Diagram
   5. Fabrication / Machine “As built drawings”.
   6. Stage wise inspection reports.
   7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
   8. Running Trial Report.
   9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
   10. Performance / Guarantee Certificates.
   11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
   12. Installation, operation & maintenance Manual.
   13. All M.O.C. Certificates.
   14. Name plate details.
   15. Critical spares for two-year operation.
   16. All product contact parts SS 316 L.
   17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
       meter.
   18. Other surfaces Matt Finished.




                                                                                     22
Annexure V

                                                     Tender No: BIC/RC9/05/2011
Project                         KINFRA Biotechnology Incubation Centre
Location                        KINFRA Hi-tech Park, Kalamassery
Facility Name                   Medicinal Plant Extraction Facility

Equipment name                  Rotary Evaporator II
Quantity                        One complete system

Rotary Evaporator II

Specification
Evaporator Flask              20 L, High quality borosilicate glass
Receiver Flask                20 L, High quality borosilicate glass
Condenser                     Glass, High surface area , 0.6M2 or more
Evaporator flask rotation     Brushless motor or equivalent technology
                              Soft start
                              0-100 rpm, Variable speed
                              RPM setting and Display – Digital
Vacuum                        Oil free diaphragm pump
                              Ultimate pressure, 2 mm mercury
                              Sealing system – PTFE or similar corrosion resistant
                              material to provide efficient and long-lasting seal.
                              Vacuum regulator
Heating Bath                  Suitable for water and oil
                              Temperature - Ambient - 150°C
                              Setting and Display – Digital
                              Temperature Accuracy - ±2°C
                              Over heat warning and automatic protection
                              Volume – Suitable to accommodate 20L flask
                              Material - High grade chemical resistant and durable
Other features                Motorised lift
                              Timer
                              Continuous monitoring of bath temperature, vapour
                              temperature and vacuum.
                              Foam detector and controller
                              Should incorporate standard safety features.
                              Cooling water (10-15°C) circulation system for
                              condenser
                              Easy and convenient connection of flasks
                              Standard Safety features

General Terms & Conditions:



                                                                                23
1. Documentation in Triplicate on receipt of P.O.
2. G.A. Drawing, Foundation/Footing Drawing.
3. Machine Drawing for Approval.
4. Wiring Diagram
5. Fabrication / Machine “As built drawings”.
6. Stage wise inspection reports.
7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
8. Running Trial Report.
9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
10. Performance / Guarantee Certificates.
11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
12. Installation, operation & maintenance Manual.
13. All M.O.C. Certificates.
14. Name plate details.
15. Critical spares for two-year operation.
16. All product contact parts SS 316 L.
17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
    meter.
18. Other surfaces Matt Finished.




                                                                                  24
Annexure VI



                                                           Tender No: BIC/RC6/06/2011
Project                               KINFRA Biotechnology Incubation Centre
Location                              KINFRA Hi-tech Park, Kalamassery
Facility Name                         Fermentation

Equipment name                        Fermenter (20 Ltr)
Quantity                              One complete system

Fermenter (20 Ltr)
 Specifications
 Volume                                        20 Ltrs
 Material of construction                      Stainless steel: O ring (EPDM silicon)
                                               SS316
 Maximum working Temp                          130 OC
 Max. pressure                                 2 Bar
 Schedule of ports                             Safety valve ,Agitator Assembly, Gas
                                               outlet, Light Gas, Pressure Gauge, Pressure
                                               transmitter port

 Agitator                                      Shaft with 3 nos. Ruston turbine impellers
                                               Single mechanical seal
                                               Speed range: 100-900 with digital control
 Temp. measurement                             Temp. Probe of 2 OC

 Accessories                                   Suitable Autoclave, air compressor and
                                               chiller unit
                                               Suitable computer system with compatible
                                               software.


General Terms & Conditions:

 1.   Documentation in Triplicate on receipt of P.O.
 2.   G.A. Drawing, Foundation/Footing Drawing.
 3.   Machine Drawing for Approval.
 4.   Wiring Diagram
 5.   Fabrication / Machine “As built drawings”.
 6.   Stage wise inspection reports.


                                                                                       25
7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
8. Running Trial Report.
9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
10. Performance / Guarantee Certificates.
11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
12. Installation, operation & maintenance Manual.
13. All M.O.C. Certificates.
14. Name plate details.
15. Critical spares for two-year operation.
16. All product contact parts SS 316 L.
17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
    meter.
18. Other surfaces Matt Finished.




                                                                                  26
Annexure VII

                                                         Tender No: BIC/RC5/07/2011
Project                             KINFRA Biotechnology Incubation Centre
Location                            KINFRA Hi-tech Park, Kalamassery
Facility Name                       Fermentation

Equipment name                      Fermenter (7 Ltr)
Quantity                            One complete system
Fermenter (7 Ltr)
 Specifications
 Volume                                      7 Ltrs
 Material of construction                    Stainless steel : SS316 O ring (EPDM
                                             silicon)
                                             Vessel type, borosilicate glass with SS tope
                                             plate.
 Maximum working Temp                        130 OC
 Max. pressure                               2 Bar
 Schedule of ports                           safety valve, Agitator Assembly
                                             Gas outlet, Light Gas, Pressure Gauge,
                                             pressure transmitter port

 Agitator                                    Shaft with 3 nos. Ruston turbine impellers,
                                             Single mechanical seal, Speed range: 100-
                                             900 with Digital control,
 Temp. measurement                           Duplex temp. sensor
                                             Measurement accuracy0.1C
                                             Control accuracy  5rpm(Up to 40C
 Speed control                               AC drive; Digital display
                                             Measurement accuracy +2 rpm
                                             Control accuracy 5rpm

 Control                                     Electronic instrumentation control with
                                             display for maintaining 100 to 1250 rpm
 Accessories                                 Suitable Autoclave, air compressor and
                                             chiller unit
                                             Suitable computer system with compatible
                                             software.



General Terms & Conditions:

   1. Documentation in Triplicate on receipt of P.O.


                                                                                      27
2. G.A. Drawing, Foundation/Footing Drawing.
3. Machine Drawing for Approval.
4. Wiring Diagram
5. Fabrication / Machine “As built drawings”.
6. Stage wise inspection reports.
7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
8. Running Trial Report.
9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
10. Performance / Guarantee Certificates.
11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
12. Installation, operation & maintenance Manual.
13. All M.O.C. Certificates.
14. Name plate details.
15. Critical spares for two-year operation.
16. All product contact parts SS 316 L.
17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
    meter.
18. Other surfaces Matt Finished.




                                                                                  28
     Annexure VIII
                                                            Tender No: BIC/RB6/08/2011
Project                                 KINFRA Biotechnology Incubation Centre
Location                                KINFRA Hi-tech Park, Kalamassery
Facility Name                           Fermentation & Central Instrumentation

Equipment name             Liquid Chromatography System for Protein Purification and
                             Fraction Collection, suitable for various chromatographic
                                                     techniques

Quantity             One complete system
Specifications
         Pump and Flow rate : 0.1 ml – 10.0 ml/min, with 0.1 ml increment
1        Solvent   Flow accuracy - ±2%
         delivery  Flow reproducibility - 0.02 RSD
                   Suitable for gradient system
                   Components coming in contact with buffers and solvents should be
                   made biocompatible material.
                   Provision for minimizing baseline disturbances due to solvent
                   pumping
  2      Sample    Provision for injecting variable volumes of sample (up to 5 ml) with
         injection auto sampler injectors

     3    Detector     UV detector- Variable wavelength, programmable
                       Multi wavelength monitoring. Simultaneous monitoring at least at
                       four wavelengths
                       Conductivity detector
                       pH Detector

  4       Fraction    Based on Time, Volume, Peak detection
          collector   Suitable for tubes of varying sizes
 5        Software    For qualitative and quantitative interpretation of data
                      Real time overview of system and separations
                      Pre-programmed method templates for protein purification
 6        Accessories Computer, Printer and essential accessories including columns (pre-
                      packed) for start up
 7        Optional    Automation of sample injection




                                                                                       29
General Terms & Conditions:


   1. Documentation in Triplicate on receipt of P.O.
   2. G.A. Drawing, Foundation/Footing Drawing.
   3. Machine Drawing for Approval.
   4. Wiring Diagram
   5. Fabrication / Machine “As built drawings”.
   6. Stage wise inspection reports.
   7. Certificate for Flame Proof Motor limits, Switches, Panel, etc.
   8. Running Trial Report.
   9. All brought out items catalogue, operation, maintenance- Manual & Certificates.
   10. Performance / Guarantee Certificates.
   11. DQ. IQ, OQ, PQ AS PER Regulatory Requirements.
   12. Installation, operation & maintenance Manual.
   13. All M.O.C. Certificates.
   14. Name plate details.
   15. Critical spares for two-year operation.
   16. All product contact parts SS 316 L.
   17. Surface finish- Contact parts Mirror finished (Ra less than or equal to 0.3 micro
       meter.
   18. Other surfaces Matt Finished.




                                                                                     30
ANNEXURE VIII

BANK GUARANTEE FOR EMD




BG NO.
BG AMOUNT Rs.
Valid upto :

  1. In consideration of the Managing Director of Kerala Industrial Infrastructure
     Development Corporation (here in after called “KINFRA”) having demanded
     from M/s. ………………………….. (hereafter called “Contractor”) the
     production      of    a   Bank      Guarantee     for   Rs…………./-         (Rupees
     …………………………………….. only) as Earnest Money Deposit for the due
     fulfillment by the Contractor of the terms and conditions in clause 1-10 of notice
     Inviting tender for the work of ………………………… for KINFRA
     ………………………….”. We the South Indian Bank, Tripunithura (here in
     after referred to as “Bank”) at the request of the Contractor do hereby undertake
     to pay to the KINFRA an amount not exceeding Rs…………………… (Rupees
     One ………………………………… only) on demand by KINFRA.

  2. We the …………………Bank do hereby undertake to pay the amounts due and
     payable under this guarantee without any demure, merely on a demand from the
     KINFRA stating that the amount claimed is required to meet the recoveries due or
     likely to be due from the said Contractor. Any such demand made on the bank
     shall be conclusive as regards the ‘amount due and payable by the Bank under
     this guarantee. However, our liability under guarantee shall be restricted to an
     amount not exceeding Rs. …………………….. only.

  3. We undertake to pay to the KINFRA any money so demanded not withstanding
     any dispute or disputes raised by the Contractor in any suit or proceeding pending
     before any court or Tribunal relating thereto, our liability under this present being
     absolute and unequivocal.

  The payment so made by us under this bound shall be a valid discharge of our
  liability for payment there under and the contractor shall have no claim against us for
  making such payment.

  4. We the ……………………………Bank., further agree that the guarantee herein
     contained shall remain in full force and effect during the period that would be
     taking for the performance of the said agreement and that it shall continue to be
     enforceable till all the dues of the KINFRA under or by virtue of the Managing
     Director on behalf of the KINFRA certifies that the terms and conditions of the




                                                                                       31
     said agreement have been fully and properly carried out by the said Contractor
     and accordingly discharges this guarantee.
5.   We the ………………………. Bank , further agree with the Kerala Industrial
     Infrastructure Development that the KINFRA shall have the fullest liberty without
     our consent and without effecting in any manner our obligations here under to
     vary any of the terms and conditions of the said Contractor from time to time or
     to postpone for any time or from time to time any of the powers exercisable by the
     KINFRA against the said Contractor and to forbear or enforce any of the terms
     and conditions relating to the said agreement and we shall not be relieved from
     our liability by reason of any such variation, or extension being granted to the said
     Contractor or for any forbearance, act or omission on the part of the KINFRA or
     any indulgence by the KINFRA to the said Contractor or by any such manner or
     thing whatsoever which under the law relating to sureties would, but for this
     provision, have effect of so relieving us.
6.   This guarantee will not be discharged due to the change in the constitution of the
     Bank or the Contractor.
7.   We the ……………….. Bank ., lastly undertake not to remove this guarantee
     except with the previous consent of the KINFRA in writing.
8.   This guarantee shall be valid up to ……….. 200… unless extended on demand by
     the KINFRA. Notwithstanding anything mentioned above, our liability against
     this guarantee is restricted to Rs…………………. (Rupees………………… ) and
     unless a claim in writing is lodged with us within six months of the date of expiry
     or the extended date of expiry of this guarantee, all our liabilities under this
     guarantee shall stand discharged.

Not with standing anything contained herein above.

Our liability under the Bank guarantee shall not exceed Rs……………../-
(Rupees……………)

This Bank Guarantee shall valid up to …………….

We are liable to pay guaranteed amount or any part there of under this guarantee only
and only if you serve upon us a written claim or demand on or before ……(date of
expiry of the guarantee)

Dated this ………. (in words.)



The ………………… Bank
……………………



Seal and signature of the authorized signatories of the Bank



                                                                                       32

						
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