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					Application pack




Research Fellow

Liver Sciences Section

Division of Transplantation Immunology and
Mucosal Biology

School of Medicine

Reference Number: R7/MJL/658/12-JL




Contents
 Explanatory notes, including application procedure.
 Further particulars, including:
 • Information about King’s College London, and the post;
 • Job description;
 • Person specification;
 • Summary of the terms and conditions of service.




                                                            Template version: March 2012
Explanatory notes
Please read carefully before completing the application form
Thank you for your enquiry regarding a post at King’s College London. Enclosed is a set of further
particulars for this post. These comprise: a job description and person specification; general
information about the College, School and Department; as well as the main terms and conditions of
the post.

Application procedure
Should you wish to apply for this position, please send the following:

 a completed Personal details form and Equal opportunities monitoring form (CTRL + click the link)

 a copy of a short statement setting out your reasons for applying for the post and highlighting the
  particular skill and experience which you feel you would bring to the role

 a copy of a current curriculum vitae, which should include inter alia:
  • your full name with title
  • details of your present post with date of appointment
  • education
    - degrees (subject, class, institution, date of award)
    - other academic/professional qualifications (subject, level, institution, date of award)
    - distinctions other than degrees
  • membership of professional and learned societies
  • teaching and research experience
  • administrative and management experience
  • grants obtained
  • publications

By email to:

Ms Shaivali Shah, Research Administrator, PA to Head of Liver Sciences Section. Contact e-mail:
Shaivali.shah@kcl.ac.uk

Applications should be made electronically in Word or PDF format.

Please ensure you quote reference number R7/MJL/658/12-JL on all correspondence.

Closing date: 9 July 2012

Interview date scheduled for: Within 2 weeks of closing date


Please advise your referees that they may be contacted and asked to provide a reference at short
notice.




Page 2
Equal opportunities
King's College London recognises that equality of opportunity and the recognition and promotion of
diversity are integral to its academic and economic strengths. The following principles apply in
respect of the College’s commitment to equality and diversity:
 To provide and promote equality of opportunity in all areas of its work and activity;
 To recognise and develop the diversity of skills and talent within its current and potential
  community;
 To ensure that all College members and prospective members are treated solely on the basis of their
  merits, abilities and potential without receiving any unjustified discrimination or unfavourable
  treatment on grounds such as age, disability, marital status, pregnancy or maternity, race, religion
  or belief, sex, sexual orientation, trans status, socio-economic status or any other irrelevant
  distinction;
 To provide and promote a positive working, learning, and social environment which is free from
  prejudice, discrimination and any forms of harassment, bullying or victimisation;
 To promote good relations between individuals from different groups.

Applicants with disabilities
King's College London is keen to increase the number of disabled people it employs. We therefore
encourage applications from individuals with a disability who are able to carry out the duties of the
post. If you have special needs in relation to your application please contact the Human Resources
Advisor responsible for the administration of the post.

Travel expenses
The College normally reimburses reasonable travel costs to and from interview within the United
Kingdom. Regrettably, only limited contribution to travel costs for applicants from outside the UK
may be available. Please contact the Head of Department before making your reservation.

Removal and relocation expenses
Removal and relocation expenses may be available to the successful applicant. These may include:
legal & professional fees associated with the sale and purchase of residence; travel and hotel expenses
relating to a weekend house hunting exercise in respect of the new appointee and spouse; reasonable
expenses incurred when removing furniture and personal belongings; storage of furniture and
personal belongings for up to one year; travel costs in respect of new appointee and family in
transferring to a new place of residence.

Response
We very much regret that due to limited resources and the large number of applications we currently
receive, we are only able to inform short listed candidates of the outcome of their application.
  If you do not hear from us within four weeks of the closing date, please assume that you have been
unsuccessful on this occasion. We would like to assure you, however, that every application we receive
is considered in detail and a shortlist only drawn up after careful reference to a detailed person
specification.
  If therefore, your application is not successful, we hope that you will not be discouraged and will
still apply for other suitable vacancies at King’s College London as and when they are advertised.

Thank you for your interest in King’s College London.




                                                                                                  Page 3
Further particulars
The College
King’s College London is one of the top 30 universities in the world (2011/2012 QS international
world rankings), the Sunday Times 'University of the Year 2010/11' and the fourth oldest in England.
A research-led university based in the heart of London, it has nearly 23,500 students (of whom nearly
9,000 are graduate students) from 150 countries and approximately 6,000 employees.
  King’s has an outstanding reputation for providing world-class teaching and cutting-edge research.
In the 2008 Research Assessment Exercise for British universities, 23 departments were ranked in
the top quartile of British universities; over half of our academic staff work in departments that are in
the top 10 per cent in the UK in their field and can thus be classed as world leading. The College is in
the top seven UK universities for research earnings and has an overall annual income of nearly £525
million.

There are nine Schools of Study:
 Arts & Humanities
 Biomedical Sciences
 Dental Institute
 Institute of Psychiatry
 The Dickson Poon School of Law
 Medicine
 Natural & Mathematical Sciences
 Florence Nightingale School of Nursing & Midwifery
 Social Science & Public Policy

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a
wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences
including international affairs. It has played a major role in many of the advances that have shaped
modern life, such as the discovery of the structure of DNA and research that led to the development of
radio, television, mobile phones and radar. It is the largest centre for the education of healthcare
professionals in Europe; no university has more Medical Research Council Centres.

  King's College London, Guy's and St Thomas' NHS Foundation Trust (GSTT), King's College
Hospital NHS Foundation Trust (KCH) and South London and Maudsley NHS Foundation Trust
(SLaM) are part of the King's Health Partners Academic Health Sciences Centre, a pioneering global
collaboration between one of the world's leading research-led universities and three of London's most
successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental
health services. Accredited by the Department of Health in 2009, King’s Health Partners (KHP) is one
of five academic health science centres in the UK. The four sovereign partner organisations within
KHP are committed to working cooperatively to create an internationally recognised centre of
excellence which draws upon academic expertise in medical science, basic science, social science, law
and humanities and brings together world leading research, education and clinical training and
practice within an integrated environment. KHP hosts two National Institute for Health Research
(NIHR) funded Biomedical Research Centres (BRCs) and a NIHR funded Biomedical Research Unit
in Dementia through local KCL-GSTT and KCL-SLaM partnerships respectively. These NIHR centres
and unit are specifically focused on enhancing the NHS clinical research environment, in order to
accelerate the pace of translation of basic discovery science into experimental medicine and early
phase clinical research and thus speed up the delivery of new treatments and diagnostics for patient
benefit. For more information about King’s Health Partners, visit: www.kingshealthpartners.org.

The School
King’s College London School of Medicine is one of the country’s largest and oldest medical schools,
with a history that can be traced back several centuries. The School receives more applications for
medicine than any other UK medical school and has the highest number of entry routes to its MBBS


Page 4
programme. Its leading research programmes, organised within nine divisions, were all rated 5 or 5* in
the last RAE.

With 700 staff and 2500 undergraduate and graduate students, the King's College London School of
Medicine at Guy's, King's College and St Thomas' Hospitals is one of the largest schools of medicine in
the UK.

The School of Medicine consists of nine Divisions, all of which were rated 5 or 5* for research, in the
last RAE exercise. The School hosts two MRC Centres: The MRC Centre in Transplantation and the
MRC-Asthma UK Centre in Allergic Mechanisms of Asthma. In 2006, King’s was awarded £2 million
for an Experimental Cancer Medicine Centre by Cancer Research UK and the Department of Health.
The Centre is headed by Professor Peter Parker FRS and Professor Arnand Puroshotham.

The School is closely aligned with its major NHS partner Trusts: Guy’s and St Thomas’ NHS
Foundation Trust (GSTT) and King’s College Hospital NHS Foundation Trust (KCHT) with the joint
aims of excellence in patient-centred research and training tomorrow’s doctors. In 2006, GSTT with
King’s College London as an academic partner, were awarded one of five UK Department of Health
Comprehensive Research Centres of Excellence, as part of the DoH’s ‘Best Research for Best Health’
initiative. The Centre is directed by King’s Professor Richard Trembath.

With 6,000 applications for its 400 places for medicine in 2006, the King’s College London School of
Medicine is the number one choice for undergraduate medicine in the UK. The MBBS programme has
five entry routes and as such, a diverse undergraduate population. The School is in its fifth year of its
national flagship Extended Medical Degree Programme, the UK’s first widening access to medicine
programme and has offered a fast-track MBBS programme for graduate and professional entry
students since 2004.

As part of the Foundation Programme (run by the South East Thames Foundation School), the School
of Medicine offers 15 places on its Academic Foundation Programme. The introduction of an academic
programme is in response to the MMC directive to develop the UK’s research capacity and improve
recruitment and retention of clinical scientists.

The School has a thriving graduate community. There is an exciting taught masters degree programme
including some unique and award winning Masters of Science. Every Division offers graduates
opportunities to work alongside internally renowned scientists. Some Divisions offer funding for some
four year research degrees including the British Heart Foundation four year foundation programme
(Cardiovascular Division) and Oliver Bird four year PhD programme for research into rheumatology
(Division of Immunology, Infection and Inflammatory Disease).

The School’s 12 international academic partners support global research collaborations (including
Harvard, Johns Hopkins and Emory in the US, Monash University, Melbourne, and the University of
the West Indies). King’s has the only undergraduate International Office in the UK.


The Division
The Division of Transplantation Immunology and Mucosal Biology (DTIMB) is a newly created
division built from the Department of Nephrology and Transplantation and extended to include Liver
and Gastrointestinal Tract studies. Its major research programmes include complement, coagulation
and inflammation and immune biology, T cell differentiation and T cell regulation, as well as cell and
protein therapeutics. It also includes a programme of Surgical Innovation and one on Research
Ethics. The Division serves as a base for two major cross-cutting centres: The MRC Centre for
Transplantation and The NIHR Comprehensive Biomedical Research Centre Transplant Theme.

The Department
The MRC Centre for Transplantation aims to translate basic discovery into new therapeutic,
diagnostic and prognostic applications. The MRC Centre spans several programmes of research,

                                                                                                   Page 5
including innate immunity (Hayday), complement (Sacks), coagulation (Dorling), immune biology
(Noelle) immune regulation (Lechler; Lombardi),T cell development (Lord), humanised models
(Nestle), stem cell biology (Sharpe), genetics (Solomon), imaging (Razavi) and tolerance biology
(Sanchez-Fueyo). Its science base embraces liver, kidney, pancreas, bone marrow, islets, hepatocyte
and stem cell transplantation, in what is one of the largest patient groups in Europe. The Centre
incorporates training in research ethics and legislation via links with the Centre for Medical Law and
Ethics at KCL. The MRC Centre is closely linked with the Transplant theme of the NIHR
Comprehensive Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust.

The Centre’s research and educational programme is aligned with the Division of Immunology,
Infection and Inflammatory Disease (DIIID). The Division of Immunology, Infection and
Inflammatory Diseases undertakes field-leading basic molecular research in infectious diseases and
vaccines, tumour immunology, autoimmunity, immune deficiencies, hypersensitivities and
inflammation. Its results provide a foundation for bridging the gap between pre-clinical and clinical
studies, thus maximising the potential to provide individualized therapeutics and improved
diagnostics for the large and immensely varied patient cohorts in our affiliated hospitals.

Guy’s & St Thomas’ NHS Foundation Trust and King’s College London
Biomedical Research Centre
Guy’s & St Thomas’ NHS Foundation Trust (GSTFT) and King’s College London (KCL) are one of five
National Institute for Health Research (NIHR) comprehensive Biomedical Research Centres (BRC)
under the Department of Health’s new strategy for R&D. King’s College Hospital NHS Foundation
Trust is a strategic partner in the Centre, and the Centre has strategic alliances with Barts & The
London NHS Trust and St George’s Healthcare NHS Trust. The aim of the GSTFT/KCL NIHR
Biomedical Research Centre is to create a unique Centre that enables our pipeline of excellent basic
biomedical research to deliver real change in the management of our patients. The BRC focuses on
seven research themes encompassing Asthma & Allergy, Atherosclerosis, Cutaneous Medicine,
Cancer, Immunity and Infection, Oral Health and Transplantation and has cross cutting disciplines
encompassing Genetics, Paediatrics, Imaging Sciences, Stem Cell Research, Cell and Molecular
Biophysics, Age-related diseases and Health & Social Care Research.

King’s Heath Partners

King’s Health Partners is one of the UK’s five Academic Health Sciences Centres (AHSC). It brings
together a world leading research led university (King’s College London) and three successful NHS
Foundation Trusts (Guy’s and St Thomas’, King’s College Hospital and South London and Maudsley).

The AHSC will deliver healthcare to patients, undertake health related science research and take a
leading role in teaching and education. In order to ensure that learning from research is used quickly,
consistently and systematically to improve clinical service, King’s Health Partners has established a
series of operational units called Clinical Academic Groups (CAGs). CAGs bring together people who
are experts in their field to offer patients the very best care and treatment based on research evidence
that it works. The groups bring together clinical staff such as doctors and nurses working alongside
academic researchers much more closely than has sometimes been the case in the past.

The Liver, Renal, Urology, Transplant, Gastro/GI Surgery Clinical
Academic Group

The post holder will be a member of the Clinical Academic Group which brings clinicians and
academics from across the three campuses together. The CAG is bringing forward a strategy to align
clinical, academic and training and education excellence across this large grouping. The post holder
will be expected to attend Executive meetings and to contribute to the mission of the CAG and KHP.

Clinical partners:

Page 6
Through KHP, DTIMB is closely aligned with clinical directorates at Guy’s, St Thomas’ and King’s
College Hospitals. The institute of Liver Sciences at King’s College Hospital
Liver Science Section
The Liver Science Section within DTIMB is situated on the King’s Denmark Hill Campus. It is lead by
Prof. Alberto Sanchez-Fueyo, Professor of Hepatology. The Liver Science Section forms part of the
largest Hepatology Centre in Europe and one of the largest in the world. The clinical departments
with which it works include the supraregional Liver Transplant and Paediatric Liver Services, and
tertiary referral services for Complex Hepatology and Acute Liver Failure. Its international standing
is based on the scale and distinctiveness of its clinical practice, a reputation for innovation and a track
record of high quality translational research. Annual activity includes ~ 200 liver transplants and
>300 paediatric and >3000 adult new referrals. This vast and varied clinical material provides
unique research opportunities.

Teaching and Learning - research profile and current activities

The Department comprises 13 Principal Investigators and 16 PhD/MD students within an overall
research staff of 57. Research awards for 2002-2012 amount to approximately £15 million (£1.5
million/year), including £1.6 million from research councils (MRC, BBSRC) and government
organisations (DoH, EU, NIH), £1.3 million from industry, the rest coming from charities including
Wellcome Trust, Royal Society, Children’s Liver Disease Foundation (CLDF), The Guy’s and St
Thomas’ Charity, WellChild Trust, Hayward Foundation, Pilkington Foundation, SPARKS.

The research programme comprises several major inter-linking threads. Clinically important immune
responses are a priority area of the research, encompassing the rejection of transplants, as well as
autoimmunity of the liver, and tumour-specific immunity. Single gene disorders and genetic
susceptibility to disease are being pursued in several liver diseases, with a coalescence of interests in
isolating the genetic loci modifying these conditions. Gene therapy is being pursued across all areas,
including the use of genetic manipulation, such as non-viral gene delivery systems to treat Wilson’s
disease. Research related to nutrition, in particular iron metabolism, has also been conducted,
including the investigation of the role of gastric acid suppression in limiting iron absorption in
hereditary haemochromatosis.

The facility for both clinical research and service has been significantly improved and modernized
since 2007. Three newly refurbished wards were opened in 2008, including Adult Liver Intensive
Care Unit, Paediatric Liver Intensive Care Unit and Paediatric liver Ward. About 30% the area of
Research Laboratory has been refurbished in 2007 to host researchers in the team of Liver
Transplantation and rest of the laboratory will be refurbished in 2012. New instruments, including a
latest model of Cell Analyser (BD FACs Canto II) and upgraded the liquid chromatograph-tandem
mass spectrometers for immunosuppressive drug monitoring have been purchased recently.


The Post
The successful candidate will work on a 3-year project until 31 July 2015 aiming at defining the
mechanisms involved in the development of allograft tolerance in a model of rat liver transplantation.
The post holder will need to develop a fully vascularized allogeneic liver transplantation model in rats
and employ it to determine the role of iron homeostasis in the development of allograft tolerance.
Post holder will assist Head of Liver Sciences Section in his research project and actively contribute to
the REF exercise, appropriate to the role and experience. S/he will also establish and strengthen
collaborative links with other faculty members at the Centre and with external collaborators to
promote the research and to assist in funding it.

The post will be based at the Institute of Liver Studies, Denmark Hill Campus; however, it may
require travelling between intra-sites of the college as per the requirement of the research project.



                                                                                                     Page 7
Job description
Post title                             Research Fellow in Liver Sciences Section

Department/Division/Directorate Liver Sciences Section; Division of Transplantation and Mucosal
                                Immunity

Grade                                  Grade 7

Responsible for                        Head of Liver Sciences

Responsible to                         Junior Members of staff within the Research Group and trainee
                                       students working on a similar research project as required by Head
                                       of Department


Role purpose

The successful candidate will work on a 3-year project until 31 July 2015 aiming at defining the
mechanisms involved in the development of allograft tolerance in a model of rat liver transplantation.
The post holder will need to develop a fully vascularized allogeneic liver transplantation model in rats
and employ it to determine the role of iron homeostasis in the development of allograft tolerance.

The post will be based at the Institute of Liver Studies, Denmark Hill Campus; however, it may
require travelling between intra-sites of the college as per the requirement of the research project.



Role outline - main responsibilities

Key objectives
The successful candidate should have expertise in the following:

 Conduct research of international quality in Liver Transplantation Research
 Contribute in writing up research grant applications to secure the funding for the long term growth
  of the project
 Maintain a consistent track record of published research findings, upholding an expert reputation in
  own subject area and providing guidance to staff and students on own specialist area. Build and
  uphold national/international collaborations to ensure that King's College London’s research is
  internationally competitive.
 Engage in external academic activities in accordance with the Department's research strategy and
  which will enhance its national/international research profile.
 Supervise junior staff and research degree students in their projects
 Engage in professional development as appropriate.
 Conduct vascularized orthotopic liver transplantation in rats
 Isolate mononuclear cells from rat spleens to isolate CD4 and CD8 T cells by cell sorting
 Conduct flow cytometric immunophenotypinc and functional assays.
 Conduct microarray and real-time PCR gene expression profiling of liver tissue samples from rat
  transplant recipients.
 Conduct skin transplantation in rats.
 Collect and analyse the data derived from the above experiments;
 Write up the results with a view to submission for presentation at scientific meetings and for
  publication in peer-reviewed journals.



Page 8
Communication & networking
 Communicate effectively with colleagues within the Department and senior members of staff across
  the College
 Communicate complex information orally and in writing.
 Lead and develop internal and external networks to promote the subject and the College.
 Promote the work of the Department both nationally and internationally
 Present at national and international conferences, and contribute towards high impact journal
  publications.


Decision making, planning & problem solving
 Identify areas for research, develop new research methods and extend the research portfolio.
 Obtain Animal Model License and other appropriate training required to carry out the project
 Conduct and be responsible for the completion of experiments listed above
 Design own research under the supervision of Head of Department
 Independently make laboratory work plans and consult the PI if problems are encountered
 Contribute to collaborative decision making with colleagues in area of research
 Manage the use of research resources and ensure that effective use is made of them


Service delivery
 Conduct a 3-year project until 31 July 2015 aiming at defining the mechanisms involved in the
  development of allograft tolerance in a model of rat liver transplantation. Actively lead on the
  project and conduct research of international quality
 Develop a fully vascularized allogeneic liver transplantation model in rats and employ it to
  determine the role of iron homeostasis in the development of allograft tolerance
 Contribute to the submission of publications in high impact peer-reviewed journals.
 Independently provide advice and support to Junior members of staff in the group
 Provide answers to specialist queries, providing detailed information and a range of solutions
 Deal with internal and external contacts and contribute to the writing of grant applications


Analysis & research
 Record experiments and research observations. Collect and analyse the data derived from the above
  listed experiments
 Write up the results with a view to submission for presentation at scientific meetings and for
  publication in peer-reviewed journals
 Respect the confidentiality of the group’s research results as requested by the PI
 Follow the laboratory practices established within the research group, Department and Trust
 Continually update knowledge and understanding in the field
 Identify sources of funding and contribute to the writing of grant applications
  Assess, interpret and evaluate outcomes of research

Team work, teaching & learning support
 Work within the research group and provide mutual support and encouragement
 Develop productive working relationships with other members of staff within department and
  across the division
 Attend and contribute to relevant meetings and regular seminars across the division and at the
  school
 Identify own training and learning needs and relevant training courses within or outside KCL


Sensory/physical demands & work environment


                                                                                                   Page 9
   This post may require to work outside normal working hours depending of requirement of
    experiments at the laboratory
   Travel to attend conferences and meetings within and outside the UK. Overnight stays may be
    required.
   Be aware of the risks in the work environment


Specific Aspects - indicate frequency D (daily), W (weekly), M (monthly) where
applicable:
 Intensive Display Screen Equipment work         W     Direct patient contact involving exposure prone     N/A
 (eg. data entry or digital microscopy):               procedures (EPP):

 Heavy manual handling:                          N/A Direct patient contact, no EPP                        N/A

 Highly repetitive tasks (eg. pipetting or re-   W     Work with patient specimens (eg. blood or tissue    D
 shelving books):                                      samples):

 Shift work, night work or call-out duties:      M     Work with GM organisms or biological agents         N/A
                                                       that may pose a hazard to human health:

 Work involving risk of exposure to              N/A Hazards which require health surveillance eg.         N/A
 environmental or human pathogens (eg in             respiratory sensitisers (allergens, substances with
 waste streams or soils):                            risk phrase R42, wood dust etc) or loud noise:

 Driving vehicles on College business:           N/A Food handling or preparation:                         N/A

 Work at height (eg. ladders, scaffolds etc)     N/A Work in confined spaces (eg. sump rooms, etc)         N/A

Pastoral care
   Show consideration to others
   Respect confidentiality
   Compliance at all times with the requirements of the Health and Safety regulations with
     responsibility for the health, safety and welfare of others in the working environment


Organisational chart

     Academic Head of Liver Sciences Section: Professor Alberto Sanchez-Fueyo.
     Head of Transplantation and Mucosal Biology: Professor Steven Sacks
     Clinic Head of Institute of Liver Studies: Professor Nigel Heaton




Special requirements
 You will be required to work irregular hours in accordance with the needs of the role.
 Information of a confidential nature must be kept strictly confidential and should never be
  disclosed either inside or outside of work. It should be noted that breach of confidentiality is a
  serious offence which may lead to dismissal
 This appointment is subject to Occupational Health Questionnaire along with your contract of
  employment. When the occupational Health Department have evaluated your questionnaire and
  declared that you are fit for appointment, your appointment will be formally confirmed.

Page 10
General
All staff are expected to adhere to King’s policies and procedures.

Disclosure

This vacancy has been defined as a ‘position of trust’ and is therefore exempt from the Rehabilitation
of Offenders Act (1974). As such, shortlisted candidates will be required to declare full details of any
criminal background, regardless of how old a conviction may be and the successful candidate will be
required to apply for a standard (or enhanced) Disclosure (a criminal records check) from the
Criminal Records Bureau. A criminal record will only be taken into account for recruitment purposes,
where the conviction is relevant to the position being applied for, and where this is the case, will not
necessarily bar candidates from employment. Any decision will depend on the precise nature of the
work and the circumstances and background to the offence(s). The same procedure will be followed
for College staff applying internally for a vacancy. Further information about the Disclosure scheme
can be found at www.direct.gov.uk/crb. Copies of the CRB’s Code of Practice and the College’s
Recruitment Policy for posts requiring Disclosure are available on request.

Date
1 July 2012

Please note
This job description reflects the core activities of the role and as the College and the post-holder
develop there will inevitably be changes in the emphasis of duties. It is expected that the post-holder
recognise this and adopt a flexible approach to work and be willing to participate in training.
  If changes to the job become significant, the job description should be reviewed formally by the
post-holder and line manger. The Human Resources department should then be consulted as to the
implications of the proposed changes.




                                                                                                  Page 11
Person specification
Eligibility to work in the United Kingdom
International applications will be considered for this position. If you do not have permission to enter,
remain and work in the United Kingdom you will need to pass a points-based immigration
assessment. Before you apply for this job you must ascertain whether you have sufficient points to
qualify under Tier 1 (Post study work) and/or Tier 2(General) schemes1. If you do not have sufficient
points please do not apply as you will not be granted permission to enter the United Kingdom. Click
on the following link to the points calculator: Border & Immigration Agency Points-based calculator.
  At the interview you will be asked to furnish the panel with the details of the route (Tier 1 (Post
study work) and/or Tier 2 (General) you would be eligible to follow. Please note that should you have
sufficient points this does not mean your application will be successful. In the event your application
is successful there is no guarantee that your application for a visa will be granted, in which event the
offer will be withdrawn.

                                                                         E       D
Criteria                                                                 S       E
                                                                                     HOW IDENTIFIED
                                                                                     AND ASSESSED
                                                                         S       S
                                                                         E       I   AP     Application
                                                                         N       R   AS     Assessment
                                                                         T       A
                                                                         I       B   I      Interview
                                                                         A       L   P      Presentation
                                                                         L       E   R      References

Education/qualification and training
Degree in Biological Sciences/ or Medical Degree                                            AP

Masters Degree in relevant area                                                             AP

PhD in Immunology                                                                           AP

Knowledge/skills
Proven track record of conceptual and methodological familiarity
                                                                                             AP/ I
with transplant immunology studies
Knowledge of laboratory safety and animal handling issues                                    AP/ I

Knowledge of microsurgery techniques in small animal models                                  AP/ I

Good practical and organisation skills                                                       AP/ I

The ability to attract funding                                                               AP/ I

Experience
Extensive research experience                                                                AP/ I

Previous experience of supervising a team                                                    AP/ I

A strong research reputation                                                                 AP/ I

Experience in handling and husbandry of pre-clinical rat models                              AP/ I

Experience in rat liver transplantation models                                               AP/ I



Page 12
Experience of cellular immunity, including flow cytometry and
                                                                                                    AP/ I
intracellular staining

Ability to perform T cell functional assays                                                         AP/ I

Experience of real-time PCR                                                                         AP/ I

A track record of publications in transplantation related scientific
                                                                                                    AP/ I
and/or clinical journals

Personal characteristics/other requirements
Friendly personality, Flexibility in working practice and time,
                                                                                          AP,R, I
Dedication to work

1There are two classifications – Tier 1 (Post study work) and Tier 2 (General). Highly skilled migrants are
encouraged to apply under the Tier 2 route, however this is dependent on King’s College London at its sole
discretion issuing you with a Certificate of Sponsorship.




                                                                                                         Page 13
Summary of terms and conditions of service
This appointment is made under the King’s College London Terms and Conditions of Service
Research staff, a copy of which is available from the Human Resources department on request.

Period of Appointment      Fixed-term contract for 3 years (1st September 2012-31 July 2015)

Probation                  6 months

Salary                     £38,140 to £42,883 plus 2,323 London Allowance per Annum

Annual leave               27 working days. Staff receive four additional closure days. Notification as
                           to how these days are taken is circulated at the start of the academic year.

Superannuation
This appointment is superannuable under the USS pension scheme. Staff already superannuated
under the NHS Superannuation Scheme may opt to remain in that scheme provided an application to
do so is received by the NHS scheme trustees within three months of appointment to King’s College
London. Alternatively staff may opt to participate in SERPS or take out a personal pension. Please
note that the College does not provide an employer's contribution towards a private pension plan.
  The College operates PensionsPlus by which individuals increase their take home pay by reducing
their NI contributions. Staff who join the USS pension scheme will automatically be entered into
PensionsPlus (provided you would benefit from doing so). As a result your salary will be reduced so
that you receive the PensionsPlus salary and a payment is made into your pension scheme instead.
  NB - NHS Superannuation Scheme: Medical Schools are classed as “Direction Employers” and
some benefits of the NHS Scheme are not available to Direction members.
  For further information please contact Ms Pauline Job, Payroll & Pensions Manager, King’s College
London, James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA.

Medical
All appointments to King’s are subject to Occupational Health clearance. Should you be offered this
post you will be sent an Occupational Health Questionnaire along with your contract of employment.
When the Occupational Health Department have evaluated your questionnaire and declared that you
are fit for appointment, your appointment will be formally confirmed.

Confidentiality
In the course of your work you may have access to personal or confidential information which must
not be disclosed or made available to any other person unless in the performance of your duties or
with specific permission from your Head of School/Department/Division. (In particular if your work
involves the handling of clinical samples and/or patient data, NHS policies for the maintenance of
security and confidentiality of NHS systems and data must be observed). Breaches in confidentiality
may lead to disciplinary action.

Training and Education
King’s College London recognises the importance of training in achieving its objective of pursuing
excellence in teaching, research and clinical practice through the activities of its staff. We are
committed to providing training for all members of staff so that they can perform their jobs effectively
and offering them opportunities for further development. Most training and development will occur
"on the job" and formal training opportunities are also available within King’s College London
associated hospitals trusts and through other external organisations.
  All members of staff with teaching responsibilities are encouraged to obtain formal recognition of
their professional expertise in teaching. It is the normal expectation that staff new to teaching in
higher education will register for the Post Graduate Certificate in Academic Practice (PGCAP) unless
they already possess a teaching qualification in higher education. The PGCAP is taught and managed

Page 14
by the King's Learning Institute (KLI); information about the certificate and other programmes run
by KLI can be found in their web site www.kcl.ac.uk/kli.

No Smoking Policy
King’s College London is committed to maintaining a healthy environment for staff, students and
visitors. Therefore, please note that smoking is not permitted in any of the College buildings or in
College vehicles. Smoking is also not permitted immediately outside the entrances to College
buildings or near to windows and air intake units. Staff working at associated NHS trust sites or other
premises should adhere to whatever policy is in place at these locations.




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