PID #2402! U.S. Patent #7115282
Discover Fragrance “Release on Demand”
MultiSal™ Fragrance MultiSal™ is a patented
controlled release system that utilizes microspheres to
extend the beneﬁts of fragrances and release them
upon moisture activation. The microspheres are
composed of a proprietary blend of synthetic and natural
water-sensitive polymers and oligomers. The unique
composition of MultiSal™ provides the ability to seal
and retain very volatile materials, such as aroma
chemicals and fragrances, until needed (i.e., when the
microspheres are exposed to body moisture, such as
sweating) and release them. The release kinetics of the
fragrance in response to moisture can be controlled and
extended over a longer period of time (few minutes to
MultiSal™ Fragrance microspheres are comprised of a
proprietary blend of water-soluble and water dispersible
synthetic and natural polymers, specially blended to
ensure that the ﬁnal matrix composition has superior
sealing properties to prevent cracks and other defects
from which the fragrance can leak. The composition of
the matrix is also designed to provide a substantial
- Foot Care, Deodorant/Antiperspirant, Dry Shampoo,
barrier to the permeation or diffusion of the aroma
Aerosols, Body Powder, Aroma Therapy Tablets (Toilet
chemicals. In the presence of moisture the matrix of the
Bowl, Spa Tablets, Effervescent Tablets)
microsphere dissolves or swells to slowly release the
fragrance, providing prolonged release in response to
- High retention of volatile ingredients
- Protection of aroma against oxidation
- Moisture trigger
- Easy to add to anhydrous formulations
- Particle size can be altered to incorporate in sprays
Add MultiSal™ Fragrance to formulation below 160° C.
Recommended usage for skin care products: 1 - 10%
Appearance: Equal to approved standard
Odor: Typical to the fragrance
Particle Size: 95% < 200 um
Storage: Closed container, room temperature
Shelf Life: 12 months
Fig. 1: Structure of MultiSal™: Sub-micron spheres Solubility/Compatibility: Freely dispersible in
containing the fragrance, encapsulated within the anhydrous cosmetic formulations and powders
65 Stults Road ~ Dayton, NJ 08810 ~ Phone: (609) 655-0173 ~ Fax: (609)655-9291 ~ www.salvona.com
Process Stability Fragrance Stability:
MultiSal™ Fragrance can survive various production Heat stability is used as a criteria for stability. The
processes including extrusion, homogenization, and hot MultiSal™ Fragrance microspheres were tested in a
pour on a commercial scale, resulting in stable products. Differential Scanning Calorimetric (ﬁgure 4) to determine
A sample of MultiSal™ Fragrance in a bar soap can be the enthalpy change and weight loss of encapsulated
seen in the microscopy picture below (ﬁgure 2). fragrance as a function of the temperature surrounding
Fig. 4: DSC TGA testing of MultiSal™ Fragrance shows
Fig 2: Microscopy of MultiSal™ taken from ﬁnished that it undergoes phase transition at 160° C, and a rapid
soap bar after accelerated aging (3 months, 50° C). release at 170° C. This qualiﬁes MultiSal™ Fragrance to
be used in a hot pour procedure and even baking.
Study: Moisture Triggered Release
Clinical Study: Longevity and Intensity
Headspace measurements were taken on skin treated
with an aged antiperspirant product comprised of free A clinical study was performed to determine the odor
and MultiSal™ encapsulated fragrance. The study intensity and longevity of 1.5% free fragrance (Control)
shows that MultiSal™ Fragrance technology provides compared to 1.5% MultiSal™ encapsulated fragrance
signiﬁcantly better retention of aroma chemicals during (ﬁgure 5). Results from volunteers show that the top
the aging process compared to the free fragrance. note of the free fragrance evaporates within 1-2 hours
MultiSal™ Fragrance also provides a high impact “burst” from application, while MultiSal™ encapsulation
of fragrance that was easily perceivable (ﬁgure 3). technology sustains the release throughout the course
of an entire day.
Control (Free Fragrance)! MultiSal™ Fragrance!
MultiSal™ - Dry!
Headspace (ppm) x 106!
Odor Intensity (1-5)!
MultiSal™ - Moisture-Triggered ! &"
Dihydro Linaloo! Benzyl Acetate! Lillial! !" #" $" %" &" '" (" )" *" +" #!" ##" #$" #%" #&"
FIg. 3: Graphical representation of fragrance Fig. 5: Graphical representation of the results of a
performance from an aged antiperspirant product. The clinical study comparing odor intensity and longevity of
performance of each fragrance was signiﬁcantly free fragrance compared to MultiSal™ Fragrance.
increased when MultiSal™ technology was used. Users MultiSal™ technology sustains the release of the
experienced a noticeable burst of fragrance intensity. fragrance over an entire day.
65 Stults Road ~ Dayton, NJ 08810 ~ Phone: (609) 655-0173 ~ Fax: (609) 655-9291 ~ www.salvona.com