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							Academic Research Enhancement
Award (AREA) Program

Erica Brown, PhD
Director, NIH AREA Program
National Institutes of Health



       NIH Regional Seminar…Washington, DC…June 2012
                                                       1
                                         Overview

• Background information on AREA program
• Applying for an AREA grant
• Funding for the AREA program
• Updates to the program
• Strategies for successfully competing for AREA
  funding




                                                    2
BACKGROUND INFORMATION




                         3
                 Purpose of the AREA Program



Support small-scale research projects in
the biomedical and behavioral sciences
conducted by faculty and students in
educational institutions that have not been
major recipients of NIH research grant
funds




                                               4
                          Goals of AREA Program

• Support meritorious research
• Expose students to research
• Strengthen the research environment of the
  institution




                                                  5
UNIQUE ASPECTS OF AREA
  GRANT APPLICATIONS




                         6
                       Applying for an AREA Grant…

• Funded through the R15 grant mechanism
  – Program Announcement (PA) Number: PA-12-006
• Receipt dates
  – AIDS-related research deadlines: May 7, September
    7, and January 7
  – Standard application deadlines: February 25, June
    25, and October 25
• All NIH ICs participate in the AREA program
  except FIC,NIMHD, and NCATS



                                                        7
                      Applying for an AREA Grant…

• Project period is limited up to 3 years
• Direct cost limited to $300,000 over entire
  project period
• Multiple PIs are allowed
• Research Strategy limited to 12 pages
• Grants are renewable




                                                    8
                                      Eligible Institutions

• Institutions offering baccalaureate or advanced
  degrees in biomedical or behavioral sciences
• Receives less than $6 million per year in NIH
  support (averaged over 7 years)
• Applicants should consult the list of ineligible
  institutions on the AREA Program website
   – http://grants.nih.gov/grants/funding/area.htm
• Ineligible institutions may serve as
  collaborator/consultant on an AREA grant



                                                              9
                                     Eligible Individuals

• Any individual with the skills, knowledge, and
  resources necessary to carry out the proposed
  research
  – Primary faculty appointment at AREA eligible
    institution
• PI can not have an active NIH research grant
  – May be a collaborator on an active NIH grant held by
    another PI
• PI may not be awarded more than one AREA
  grant at a time


                                                            10
                    Special Submission Requirements

• A profile of available and former students at the
  institution (Facilities and Other Resources)
   – Demographics
   – Number who are enrolled in baccalaureate and
     doctoral degree programs (if applicable)
   – Number who have obtained advanced degrees in the
     health-related sciences
• A description of the special characteristics of the
  institution that make it appropriate for an AREA
  grant (Facilities and Other Resources)



                                                        11
                    Special Submission Requirements

• A brief description of the resources available at
  other proposed research sites (Facilities and Other
  Resources)
• A statement of institutional support for the
  proposed research project (Facilities and Other
  Resources)
• Evidence of the PI’s experience in supervising
  students on a research project (Biosketch)
   – Summary in Personal Statement
   – Highlight publications that involved students



                                                        12
                      A Special Note about the Budget

• Unlike most NIH grants, funds for all project years
  are awarded upfront (project start date)
• Include the total requested budget for all years of
  the proposed project in Budget Period 1.
   – For example, if applying for a 3-year grant, request all
     funds in year 1.
• If the direct costs for all years is $250,000 or less,
  use the Modular Budget format
• If the direct costs for all years is more than
  $250,000, use the R&R Detailed Budget
• Note: Progress reports still due annually

                                                                13
FUNDING STATISTICS FOR
   AREA PROGRAM




                         14
                                      NIH Funding Statistics for AREA Program
                                    1600                                                                                                                       100%


                                                                                                                                                               90%
                                    1400

                                                                                                                                                               80%
Number of Applications and Awards




                                    1200
                                                                                                                                                               70%

                                    1000
                                                                                                                                                               60%




                                                                                                                                                                      Success Rate
                                     800                                                                                                                       50%


                                                                                                                                                               40%
                                     600

                                                                                                                                                               30%
                                     400
                                                                                                                                                               20%

                                     200
                                                                                                                                                               10%


                                       0                                                                                                                       0%
                                              2002



                                                         2003



                                                                    2004



                                                                                2005



                                                                                          2006



                                                                                                       2007



                                                                                                                   2008



                                                                                                                                  2009



                                                                                                                                          2010



                                                                                                                                                        2011
                                                                                          Fiscal Year

                                                        Number of Applications Reviewed          Number of Applications Awarded          Success Rate



                                      Excludes awards made with American Recovery and Reinvestment Act (ARRA) funds
                          Policy Changes in FY 2010

• Increased the cap on direct costs from $150,000
  to $300,000 for up to 3 years
• Increased institutional eligibility cap from $3M to
  $6M per year




                                                        16
                                      NIH Funding Statistics for AREA Program
                                    1600                                                                                                                            100%
                                                                                                                                                      $77.5M
                                                                                                                                                                    90%
                                    1400

                                                                                                                                                                    80%
Number of Applications and Awards




                                    1200
                                                                                                                                                                    70%
                                                                                                                                            $52.3M
                                    1000
                                                                                                                                                                    60%




                                                                                                                                                                           Success Rate
                                                                                                    $45.2M
                                                                                                                             $37.3M
                                     800                                                                          $44.4M                                            50%
                                                                                          $37.9M
                                                                           $39.7M
                                                                $37.6M                                                                                              40%
                                     600
                                           $25.2M $30.5M
                                                                                                                                                                    30%
                                     400
                                                                                                                                                                    20%

                                     200
                                                                                                                                                                    10%


                                       0                                                                                                                            0%
                                              2002



                                                         2003



                                                                    2004



                                                                                2005



                                                                                             2006



                                                                                                          2007



                                                                                                                      2008



                                                                                                                                     2009



                                                                                                                                               2010



                                                                                                                                                             2011
                                                                                             Fiscal Year

                                                        Number of Applications Reviewed             Number of Applications Awarded            Success Rate



                                      Excludes awards made with American Recovery and Reinvestment Act (ARRA) funds
                          IC Funding Statistics for 2011
        NIH          Applications   Applications   Success
Institutes/Centers    Reviewed        Awarded        Rate
    NIAAA                 9               1         11.1%
    NIA                   66              7         10.6%
    NIAID                172             29         16.9%
    NIAMS                 49              6         12.2%
    NCCAM                 24              4         16.7%
    NCI                  185             23         12.4%
    NIDA                  34              6         17.6%
    NIDCD                 23              9         39.1%
    NIDCR                 18              4         22.2%
    NIDDK                 53              8         15.1%
    NIBIB                 31              3          9.7%
    NIEHS                 47              4          8.5%
    NEI                   20              2         10.0%
    NIGMS                313             62         19.8%
    NICHD                114              8          7.0%
    NHGRI                 6               1         16.7%
    NHLBI                111              9          8.1%
    NLM                   2               0          0.0%
    NIMH                  49              5         10.2%
    NINR                  38              2          5.3%
    NINDS                 87             22         25.3%
    NCRR                  3               1         33.3%
    FY Total            1454            216         14.9%



                                                             18
WHAT’S NEW?




              19
                   Recent Changes to the Review of
                                     AREA Grants
• Cluster AREA grants within study sections or in
  Special Emphasis Panels (SEPs)
• Greater inclusion of AREA community in review
  panels
• Revised and Clarified the AREA Program
  Announcement (PA)
  – FY 2013 (Feb. 25 receipt date)
• Educate reviewers about the unique aspects of
  AREA grants and the changes to the PA



                                                     20
                                       Changes to AREA PA

• Strengthened language about inclusion of students
   – “Encouraged” to “should”
• Clarified budget language
   – Request entire budget in Budget Period 1
   – Modular budget vs. detailed budget format
• Revised review criteria
   – Evaluate goals of program
   – Evaluate all R15 special submission requirements
   – Softened language of the expected Overall Impact and
     Significance of the proposed research
• Implementation: FY 2013 (Feb. 25, 2012 receipt date)


                                                            21
STRATEGIES FOR SUCCESS




                         22
                   Build and Sustain a Vital Research
                                         Environment
• Understand the NIH extramural research program
   – Know the guidelines, deadlines, submission &
     correction process, and review criteria
• Make a commitment to establishing an environment
  in which research can succeed
  – Start up packages for equipment and supplies
  – Credit for student involvement in research
• Consider the importance of collaborative research in
  establishing a successful research environment
  – Tenure decisions



                                                         23
                     Build and Sustain a Vital Research
                                           Environment
• Do not pressure investigators to apply if their
  projects are not ready for peer review
   – Only 2 submissions allowed per project
   – Quality over quantity; submit best application
• Help investigators with the “Facilities and Other
  Resources” section of application
   – Profile of student body
   – Description of the institution and research environment
   – Letter of institutional commitment to research project
                  Strategies of Successful Investigators

• Find the NIH Institute or Center that supports your
  area of research
   – Research objectives of the NIH Institute and Centers
     http://grants.nih.gov/grants/funding/area_grant_objectives.htm
   – AREA contacts at each NIH Institute and Center
     http://grants.nih.gov/grants/guide/contacts/parent_R15.html

• Include a cover letter suggesting an appropriate
  Institute and up to three appropriate study sections
   – Study Section expertise
     http://cms.csr.nih.gov/PeerReviewMeetings/CSRIRGDescription
     New/
   – Study Section rosters
     http://www.csr.nih.gov/Roster_proto/sectionI.asp


                                                                      25
               Strategies of Successful Investigators

• Include a collaborator or consultant if you don’t
  have the necessary expertise or resources
• Understand the review criteria and the review
  criteria questions
   – Each question should be addressed in the application
• In resubmitted applications, respond thoroughly
  and diplomatically to all of the reviewer
  comments
• AREA grant is a research award, not a training
  award
   – Focus on hands-on research not course work

                                                            26
                    Strategies of Successful Investigators

• Address the AREA-specific programmatic goals in the
  application
   – Support meritorious research
      • Research should contribute to the field
      • Results should be publishable
   – Expose students to research
      • Profile of available and former students at the institution
      • Experience of the investigator in working with students
      • How students will be incorporated into the research project
      • How students will benefit from this research experience
   – Strengthen the research environment
      • The suitability of the institution for an award
      • The impact the AREA grant will have on the institution


                                                                      27
                                Thank you…




     Erica Brown, PhD
Director, NIH AREA Program
   ebrown1@mail.nih.gov


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                                             28

						
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