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									A. RFP NUMBER: ST121037                              B. DATE ISSUED: December 2, 2011
C. ISSUED BY:                   D. ADDRESS OFFERS TO:
                                D.1. HARD COPIES (if required):   D.2. ELECTRONIC COPIES:

SAIC-Frederick, Inc.     SAIC-Frederick, Inc.                lewisjk@mail.nih.gov
Research Contracts Dept. Research Contracts Dept.
P.O. Box B               92 Thomas Johnson Dr; Suite 250
Frederick, MD 21702      Frederick, MD 21702
E. FOR INFORMATION REGARDING THIS SOLICITATION CONTACT:
E.1. NAME: Jeanne Lewis                       E.2. EMAIL: lewisjk@mail.nih.gov
IMPORTANT:

F. To be considered for award, Offers must be received at the location specified in Block D.2. above by
   5:00, Eastern time, January 9, 2012, . Offers must be clearly identified with the solicitation number
   provided in Block A above.

G.      Introduction
This solicitation is issued by SAIC-Frederick, Inc. (SAIC-F), a wholly owned subsidiary of Science
Applications International Corporation under its prime contract with the National Cancer Institute (NCI)
at Frederick. The provisions and clauses contained herein and attached are influenced by and reflect the
relationship of the parties in that Agreement, which was awarded and is administered under the
provision of the Federal Acquisition Regulation (FAR). This effort is fully financed using Federal American
Recovery and Reinvestment Act (ARRA) funds.

H.      Request for Proposal (RFP) Package
This RFP package consists of two documents: this one, which is referred to as the RFP Document, and
another, which is referred to as the Agreement Document. The Agreement Document is being provided
in advance of award, so that the Offeror may review SAIC-F Terms and Conditions. A final Agreement
Document will be issued at time of Award.

I.      Agreement Type/Procurement Objective
It is anticipated that this RFP will solicit proposals from qualified potential sources in response to the
technical challenges and objectives described herein and attached. The resulting Agreement will be Firm
Fixed Price as described in FAR Part 16.202-1. A Firm Fixed Price Agreement provides for a price that is
not subject to any adjustment as a result of the Subcontractor’s cost experience. The Subcontractor may
not exceed the established fixed amount without the prior approval of the Contracting Officer.




RFP No. ST12-1037                                                                               Page 1 of 28
J.      Instructions to Offerors
        J.1.    General Information
        IMPORTANT:

        PROPOSALS MUST BE SUBMITTED ELECTRONICALLY IN EITHER SEARCHABLE ADOBE ACROBAT,
        MICROSOFT WORD, OR MICROSOFT EXCEL FORMATS AS APPLICABLE. SAVED FILES MUST NOT
        EXCEED 15 MB IN SIZE; THIS MAY REQUIRE THAT A DOCUMENT BE BROKEN INTO TWO OR
        MORE SEPARATE FILES.

        ALL OFFERS MUST BE RECEIVED BY 5:00 Eastern, January 9, 2012. Proposals shall be submitted
        to Jeanne Lewis at lewisjk@mail.nih.gov.

        All submissions must be clearly identified to include the Offeror’s name, Principal Investigator’s
        name (or Project Manager’s name), and RFP number.

        Late offers will not be considered for award.

        J.2.    Questions Regarding This Solicitation
        IMPORTANT:

        ALL QUESTIONS OR REQUESTS FOR CLARIFICATION MUST BE EMAILED TO Jeanne Lewis at
        lewisjk@mail.nih.gov. Questions shall be provided in one concise submission with references to
        the relevant sections(s) of the RFP. The questions submitted will be compiled with responses
        into one document that will be incorporated as an amendment to this.

        Questions or requests directed to any other individual other than the individual named in this
        section will not be considered valid, nor will there be a response provided. If deemed necessary
        or desired by the SAIC-F Contracting Officer, a second round of questions may be solicited.

        J.3.    Proposal Instructions to Offeror
        To be considered responsive to this RFP, the Offeror must provide and/or complete the
        following requirements:

                J.3.a.    VOLUME 1 – RFP

                This document shall contain the RFP Document with all items completed as required
                below and submitted as prescribed in J.1. General Information above. The document
                shall be clearly named Volume 1 – RFP.

                Requirements:

                        Complete Section L. Representations and Certifications of this document.


RFP No. ST12-1037                                                                              Page 2 of 28
                        Complete Section M.1. Subcontracting Certification of this document and, if
                         applicable, provide a Subcontracting plan as described in FAR 19.704. A
                         Subcontracting      plan    template        may       be      found     at
                         http://www.hhs.gov/osdbu/AgreementPlan-FY08.doc.

                        Complete Section M.2. E-Verify Compliance

                        Complete Section N. Offeror Representatives identifying the (1) Official
                         Authorized to Negotiate on behalf of Offeror, (2) Offeror Key Personnel, (3)
                         Offeror Invoice Representative, (4) Offeror Invoice Remittance Address, and, if
                         applicable.

                        Complete Section O. Offeror Signature designating the individual duly
                         authorized to make an Offer on behalf of the Offeror.

                        If exceptions to the Terms and Conditions are requested, complete RFP
                         Attachment 4 – Exceptions Request.

                        Complete RFP Attachment 4 – American Recovery and Reinvestment Act of
                         2009 Representations and Certifications.

                        Complete and submit with the offer an IRS Form W-9. All Offerors MUST be
                         registered with the Central Contractor’s Registration (CCR). Offerors may
                         register with CCR at http://www.ccr.gov/Start.aspx. The address included on the
                         W-9 MUST match the address registered at CCR, ORCA, and/or included with
                         the Representations, Certifications, and Other Statements of Offerors.

                J.3.b.    VOLUME 2 – TECHNICAL PROPOSAL

                This document shall contain the Technical Proposal Document with all items completed
                as required below and submitted as prescribed in J.1. General Information above. The
                document shall be clearly named Volume 2 – Technical Proposal.

                Requirements:

                The Offeror must provide proposals that clearly demonstrate the Offeror’s current
                capabilities to meet each of the various requirements as established in RFP Attachment
                1 – Statement of Objectives and in accordance with the guidelines set forth in RFP
                Attachment 2 – Technical Proposal Information Requirements. Responses shall be
                focused, succinct, and free of extraneous data or information responding solely to the
                requirements contained in this RFP. Additionally, technical proposals shall be formatted
                in such a way to clearly cross-reference the relevant sections in the RFP.

                IMPORTANT:

                Technical proposals shall not include the detailed cost and pricing information.

RFP No. ST12-1037                                                                              Page 3 of 28
                         Technical Proposals must include page numbers on all pages, including all
                          appendices and attachments. There must also be a cover page that lists all
                          appendices and attachments.

                         Please refer to RFP Attachment 2 – Technical Proposal Information
                          Requirements for an outline of specific information to be addressed in the
                          Technical Proposal and for maximum page limitations for each of the required
                          sections.

                 J.3.c.    VOLUME 3 – COST AND PRICE PROPOSAL

                 This document shall contain the Cost and Price Proposal Document with all items
                 completed as required below and submitted as prescribed in J.1. General Information
                 above. The document shall be clearly named Volume 3 – Cost and Price Proposal.

                 Requirements:

                 Offerors shall submit Cost and Price Proposals that provide a budgetary estimate for the
                 project proposed. The Cost and Price Proposal shall include the information required in
                 RFP Attachment 3 – Cost and Price Proposal Information Requirements. .

        J.4.     RFP Point of Contact
        The Point of Contact for this RFP is identified below.

        Name:             Jeanne Lewis
        Address:          SAIC-Frederick, Inc.
                          92 Thomas Johnson Drive, Suite 250
                          Frederick, MD 21702
        Email:            lewisjk@mail.nih.gov

        J.5.     RFP Attachments
        The following are considered attachments to this RFP:


         RFP Attachment No. Document Description


                     1           Statement of Objectives

                     2           Technical Proposal Information Requirements

                     3           Cost and Price Proposal Information Requirements

                                 American Recovery and Reinvestment Act Representations and
                     4
                                 Certifications



RFP No. ST12-1037                                                                             Page 4 of 28
K.      Proposal Evaluation Criteria
        K.1.    Basis for Award
        SAIC-F intends to award an Agreement(s) resulting from this RFP to the responsible
        organization(s) whose offer(s) conforming to the RFP will be of the best value to SAIC-F, price
        and other factors considered. Although technical factors are of paramount consideration in the
        award of an Agreement, price is also important to the overall award decision.

        K.2.    Potential Award Without Discussions
        SAIC-F reserves the right to award an Agreement without discussions if the Contracting Officer
        determines that the initial offer(s) are fair and reasonable and that discussions are not
        necessary. Therefore, the Offeror’s initial offer should contain the Offeror’s best terms from a
        price and technical standpoint. However, SAIC-F reserves the right to conduct discussions if later
        determined by the Contracting Officer to be necessary. SAIC-F may reject any or all offers;
        accept other than the lowest priced offer; and waive informalities and minor irregularities in
        offers received.

        The assessment of the offers received in response to this RFP will be carefully considered
        against the needs of SAIC-F and the NCI. This assessment is not intended to be a solely
        mechanical or mathematical analysis of an offer, but rather the product of both objective and
        subjective measurements and judgments of the source selection officials after consideration of
        the relevant information.

        K.3.    Proposal Evaluation Factors
        Evaluation of the offers submitted will be considered against the following evaluation factors.

                K.3.a.     Technical Approach

                        The Offeror demonstrates good understanding of the scope, objectives, and
                         challenges of this project.

                        The proposed approach is capable of meeting project objectives as stated in the
                         SOO.

                The solution proposed is within the scope of the effort.

                K.3.b.     Team and Key Personnel

                        Project Organization covers all skills needed to execute this project.

                        Key personnel have demonstrated experience in the technical evaluation factors
                         given above that are applicable to their role.



RFP No. ST12-1037                                                                                 Page 5 of 28
                        Evidence has been provided that Key Personnel have performed successfully in
                         the past in the role proposed.

                        Key personnel are bid at a level of effort commensurate with their proposed
                         role.

                K.3.c.     Experience and Past Performance

                        The Offeror has demonstrated experience in the technologies and procedures
                         required to execute this project.

                        Past performance examples are for projects of similar size, scope, and technical
                         objectives.

                        Evidence of successful performance on these projects has been provided.

                        Project Plan and Work Breakdown Structure

                        The project plan is sufficient to meet the objectives in the Statement of
                         Objectives.

                        Project schedule is reasonable given the tasks proposed.

                        Milestones are consistent with SOO guidance.

                K.3.d.     Management

                        Mechanism by which budget and costs are controlled has been described.

                        Project risks have been identified and risk mitigation strategies have been
                         identified.

                        Subcontractor roles are defined and management controls are adequate.

                K.3.e.     Cost Reasonableness

                        Costs proposed are commensurate with the requirements bid.

L.      Representations and Certifications
In order to be considered responsive, all offers must include a completed set of general
Representations, Certifications, and Other Statements of Offerors in one of the two manners indicated
in this section. If the Offeror is registered and current with the Online Representations and Certification
Application (ORCA) website (https://orca.bpn.gov/) then only the provision of a current Dun &
Bradstreet (DUNS) number is required and should be provided below. If the Offeror is not registered and
current with ORCA, the Offeror must submit a completed and signed hard copy of the Representations



RFP No. ST12-1037                                                                               Page 6 of 28
and Certifications which      may    be    accessed   and   printed    from   http://rcb.cancer.gov/rcb-
internet/forms/rcneg.pdf.

Please indicate your organization’s status by checking the appropriate response:

        Our organization’s DUNS Number is Insert DUNS Number.

        Our organization is registered and current with ORCA.

        Our organization is NOT registered with ORCA; we have submitted one copy of the
        Representations and Certifications with our Offer.

M.      Certifications
        M.1. Subcontracting Certification
        In accordance with the terms of its prime contract, under which a resulting award will be issued,
        SAIC-F is committed to maximizing small business subcontracting opportunities to the maximum
        extent practicable. In pursuit of this objective, please complete and include in your technical
        proposal the following certification providing the percentage of effort that will be conducted by
        employee personnel during the execution of the Statement of Work as provided herein
        (including any option tasks/periods, as applicable):

        By submission of this signed offer, Insert Organization Name hereby certifies that   %* of
        the effort expended in the execution of the Statement of Work as provided by SAIC-F in
        solicitation number Insert RFP Number (Block A Above) will be conducted by employees of this
        organization.

                      By:

                    Title:


               Signature:

                    Date:



        *If the percentage of work to be conducted by employees of your organization is less than 100%
        and the total cost proposed is $650,000 or more a small business Subcontracting plan as
        described in FAR 19.704 is required prior to award of an Agreement. Failure to provide an
        acceptable Subcontracting plan in a timely manner may render your organization ineligible for
        award.       A     Subcontracting      plan     template      may       be        found      at
        http://www.hhs.gov/osdbu/AgreementPlan-FY08.doc.



RFP No. ST12-1037                                                                             Page 7 of 28
        M.2. E-Verify Compliance (FAR 52.222-54)
                 Subcontractor is currently enrolled in the DHS E-VERIFY system (Employment Eligibility
                 Verification) Please provide a copy of the Edit Company Profile page as proof of
                 enrollment.

                 Subcontractor is currently NOT enrolled in the DHS E-VERIFY system

        To be eligible for award Subcontractor will be required to enroll in E-VERIFY within 30 days from
        date of award and must provide a copy of the Edit Company Profile page. To access E-verify,
        you may visit https://e-verify.uscis.gov/enroll.

N.      Offeror Representatives
        N.1.     Offeror Authorized Representative
        The following individual(s) is/are the designated representative of the Offeror. This will be the
        Official authorized to negotiate and sign the resulting Agreement:

        Name

        Title

        Organization

        Address Line 1

        Address Line 2

        City, State, and ZIP Code

        Phone:

        Fax:

        Email:


        N.2.     Offeror Technical Representative(s) and/or Key Personnel
        The following individual(s) is considered to be essential to the work being performed hereunder,
        and shall not be re-assigned, removed, or substituted without the concurrence of the
        Contracting Officer:

         Name                               Title                          Email Address

                                            Principal Investigator



RFP No. ST12-1037                                                                             Page 8 of 28
                                             Program Manager




        N.3.     Offeror Invoice Representative(s)
        The following individual(s) is the designated representative to submit invoices:

        Name

        Title

        Organization

        Address Line 1

        Address Line 2

        City, State, and ZIP Code

        Phone:

        Fax:

        Email:


                 N.3.a. Offeror Invoice Remittance Address

                 Organization

                 Address Line 1

                 Address Line 2

                 City, State, and ZIP Code



O.      Offeror Signature
The following individual is duly authorized to make an Offer on behalf of the Offeror. Offer shall be valid
for 90 days.



RFP No. ST12-1037                                                                               Page 9 of 28
Signature

Name

Title

Organization

Address Line 1

Address Line 2

City, State, and ZIP Code

Phone:

Fax:

Email:




RFP No. ST12-1037           Page 10 of 28
Attachment 1: Statement of Objectives




RFP No. ST12-1037                       Page 11 of 28
                                                                                      RFP —Attachment 1


 TITLE: Validation of Candidate Mutations from Discovery Phase of Complete Molecular Characterization in the
                                             TARGET Initiative


Background:

Genomic alterations, such as translocations, copy number alterations, DNA methylation or sequence
altering somatic mutations underlie the cause of most cases of cancer. However, only some of the
genomic alterations are associated with clinical outcome or are potential targets for directed therapies.
Identification of such disease-associated mutations can significantly affect the approach to diagnosis,
risk evaluation, and therapy.

Cancer genomics has entered an era in which 2nd generation sequencing allows the comprehensive
characterization of the genome, epigenome, exome and transcriptome and thereby the discovery of
many new candidate genes potentially involved in cancer initiation, progression, metastasis and
resistance to treatment (understanding the biology and the clinical impact). The identification of these
candidates is just the first step in the process towards clinical translation. The next step is to determine
the prevalence of verified mutations in a separate cohort of patients. Clinical implications of the
mutations will be determined by correlating presence of mutations with clinical outcome both
individually (univariate) and in the context of known prognostic factors (multivariate).


TARGET Initiative:

The goal of NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET)
Initiative is to identify valid therapeutic targets in childhood cancers so that new, more effective
treatments can be rapidly developed. There is a need for new treatment approaches to childhood
cancers. Improvements in health outcomes of the last several decades for children with cancer have
slowed. Furthermore, the current treatments for childhood cancers can have serious short- and long-
term side effects, and recent molecularly targeted therapy advances have been largely limited to the
treatment of adult cancers. The TARGET Initiative seeks to help bring the new era of targeted therapy to
bear on the cancers that afflict children.

The TARGET initiative has developed the infrastructure to identify and verify the novel candidate
disease-associated alterations that may be part of the pathways essential in the pathogenesis of the
cancers studied. The determination of the prevalence of these alternations, mostly mutations within
genes, is the goal of the SOO/RFP. For more information about TARGET visit http://target.cancer.gov/.


Statement of Objectives:

The purpose of this Project is to provide 2nd generation sequencing resources for recurrence testing for 2
- 6 of the cancers studied by the TARGET initiative. To that end this Statement of Objectives is provided
in this RFP for the Offeror to provide what they believe is the best methodology, equipment and price to
meet the objectives as well the best use of the samples provided.

The genes or rearrangement regions (assume 0.5-4 kb per locus, either discontinuous, i.e. exons, or
continuous, chromosomal regions) will be selected by the TARGET project teams based upon criteria

RFP No. ST12-1037                                                                                Page 12 of 28
                                                                                    RFP —Attachment 1


that may include (1) the probability that a mutation may occur in 5% or more of cases in a given cancer;
(2) potential therapeutic impact; and (3) biological interest. Each project team will select the samples to
be sequenced, isolate the DNA and confirm its quality (size of the fragments and quantitation by
picogreen).

As detailed in the Technical Proposal requirements, the offeror’s proposals should include specifics
which address the following requirements in detail. Once the award decision is made, these objectives
will be replaced with the scope of work and quantities to be provided.

    1. Achieve 90% sequencing of the defined genomic target, to high quality.

    2. Achieve pass rate of 95% of the samples sequenced to the above quality

    3. DNA from pediatric cancers is limiting. Offeror’s needed quantity must be little as possible.

    4. How would the costs and the DNA quantity, be affected if the sequencing required the following
       number of genes (divided into exons with at least 20 flanking bases) or chromosomal
       rearrangements e.g. translocations, rearrangements (coding regions/alternative splice forms in
       the 500-4000 nt range):
                100 targets
                200 targets
                300 targets
        with or without case-matched normal in:
                100 cases
                150 cases
                200 cases
       Final option, 50 targets in 500 cases

    5.    Offeror’s proposed quantities and prices shall be provided in the technical proposal and shall be
         incorporated into the final statement of work and in the pricing section of the Agreement.




 Number         of                     Price w/o case- Price With case- Amount of DNA
 Cases               Number of Targets matched normal matched normal required
 100                 100
                     200
                     300
 150                 100
                     200
                     300
 200                 100
                     200
                     300
 500                 50


RFP No. ST12-1037                                                                              Page 13 of 28
                                                                                   RFP —Attachment 1




        SAIC/NCI will select the combination of targets and cases based on the need for each cancer
        type as well as the costs in resources (money and DNA) that will be validated through this
        contract.

    6. If validation sequencing will be done in tumor tissue only, would it be feasible to follow-up those
       cases with mutations and sequence only that site in the normal DNA? How does this impact on
       costs?

    7. Once DNA is received and passes internal QC, how long will it take to generate the data for the 3
       case number options? Please complete the following table providing in weeks how long the
       production will take for each option as well as the data. The completed table will be used as
       the basis for the Agreement schedule.



                                    Production time Production time Production time
 Number        of                   w/o        case- with      case- to generate the
 Cases            Number of Targets matched normal matched normal data
 100              100
                  200
                  300
 150              100
                  200
                  300
 200              100
                  200
                  300
 500              50


    8. The Period of Performance is to be determined based on the proposed production times in the
       table above.




RFP No. ST12-1037                                                                             Page 14 of 28
Attachment 2: Technical Proposal Information Requirements




RFP No. ST12-1037                                      Page 15 of 28
                                                                                   RFP —Attachment 2


Technical Proposal Information Requirements
Below is a synopsis of the technical information requested from Offerors. Refer to the RFP Document for
other requirements and information. Offerors are asked to be direct and concise in presenting
information that clearly describes the proposed project. Offerors should realize that the clarity of their
proposals is important in communicating the overall project goals to reviewers and that a concise and
well formulated proposal will be more easily reviewed and evaluated.

General Considerations:
Technical proposals shall provide a detailed discussion of the proposed work to enable an in-depth
review of the specific technical requirements. Specific attention must be given to addressing the
requirements as specified and ordered in the Statement of Work.

Specific Considerations:
In addition to the general considerations above, the Offeror shall address the following areas in their
proposals:

A.      Executive Summary ( 1 page limit)
The summary shall contain the most important elements from sections below but should at a minimum
clearly specify the following elements:

       Brief identification and qualifications for this solicitation of your organization/team, including
        any Subcontractors and their roles.

       The purpose and anticipated end result of this proposal.

       Technical and management approach discriminators.

       Cost summary.

The summary shall be on separate pages or include a section break before the rest of the proposal.

B.      Technical Approach (10 page limit)
        B.1.    Understanding
        Provide your understanding of what needs to be done, the scope of the work, the estimated
        length of time for the work to be finished, the challenges, and how you are going to address
        those challenges.




RFP No. ST12-1037                                                                             Page 16 of 28
                                                                                  RFP —Attachment 2


        B.2.    Approach
        Describe a sound technical approach to the proposed work and critical technology challenges
        required for accomplishing proposed tasks. Describe any unique aspects of the approach, and
        why you believe it will be the most efficient and effective way of achieving project objectives.
        Describe how this approach will meet both project and overall objectives as described in the
        SOO.

        B.3.    Question/answers from the Statement of Objectives which must be
                provided in detail.
        Listed below are the questions and tables from the Statement of Objectives to be completed by
        the Offeror in detail. The offeror’s proposals should include specifics. The offeror shall also
        provide a sample and/or descriptions of the data they would normally provide for such a
        project.

        1.      How will the offeror achieve 90% sequencing of the defined genomic target, to high
                quality.
                a.       What is the quality of each base, specifically the sensitivity and specificity?
                b.       What is the length of each “read”?
                c.       How many reads per site will be generated?
                d.       How are mutations detected?
                e.       How are mutations reported?
                f.       Can they submit the BAM files to either dbGAP at NCBI or to the TARGET DCC,
                         http://target.cancer.gov/dataportal/ (at NCI)?
                g.       Prior experience with projects of this scope.

        2.      How will the offeror achieve pass rate of 95% of the samples sequenced to the above
                quality

        3.      DNA from pediatric cancers is limiting
                a.     Will the offeror propose to use multiplex PCR or custom capture? If the latter
                       what product will be used?
                b.     Will the offeror do indexing?
                c.     Will indexing be pre- or post- capture or PCR?
                d.     How would the product be affected by using Qiagen amplified DNA?
                e.     How much of the flanking region of the exons will be captured?

        4.      How would the costs and quantity of DNA, be affected if the sequencing required the
                following number of genes (divided into exons with at least 20 flannking bases) or
                chromosomal rearrangements e.g. translocations, rearrangements (coding
                regions/alternative splice forms in the 500-4000 nt range):



RFP No. ST12-1037                                                                           Page 17 of 28
                                                                                          RFP —Attachment 2


               100 targets

               200 targets

               300 targets

        with or without case-matched normal in:

               100 cases

               150 cases

               200 cases

               Final option, 50 targets in 500 cases

        5.          It is important that all the above questions be answered in detail.

        6.      Please fill in the following table. The information provided in the table will enable us to
                analyze fully the options provided in the proposals to allow for the best alternative(s).
                The completed table will be used as the basis for the Agreement quantities and
                prices.


   Number of                                 Price w/o case-     Price With case-     Amount of DNA
     Cases             Number of Targets     matched normal      matched normal         required
      100                   100
                            200
                            300
       150                  100
                            200
                            300
       200                  100
                            200
                            300
       500                   50


        SAIC/NCI will select the combination of targets and cases based on the need for each cancer
        type as well as the costs in resources (money and DNA) that will be validated through this
        contract.




RFP No. ST12-1037                                                                                 Page 18 of 28
                                                                                     RFP —Attachment 2


        7.       If validation sequencing will be done in tumor tissue only, would it be feasible to follow-
                 up those cases with mutations and sequence only that site in the normal DNA? How
                 does this impact on costs?

        8.       Once DNA is received and passes internal QC, how long will it take to generate the data
                 for the 3 case number options? Please complete the following table providing in weeks
                 how long the production will take for both options as well as the data. The completed
                 table will be used as the basis for the Agreement delivery schedule.




                                      Production time          Production time     Production time
     Number of                        w/o case-                   with case-       to generate the
       Cases        Number of Targets matched normal           matched normal           data
        100              100
                         200
                         300
       150               100
                         200
                         300
       200               100
                         200
                         300
       500                50


C.      Team and Key Personnel (5 page limit)
        C.1.     Introduction
        Introduce your organization and/or team here. Give an overview of the capabilities brought to
        address this effort.

        C.2.     Organization and/or Team
        Describe your organization and show chain of command and lines of communication to be used
        for technical proposal evaluation purposes.

        Describe each proposed individual’s role and the percentage of their time that is being bid, and
        a brief description of their qualifications. Fuller experience descriptions may be included in the
        appendix.




RFP No. ST12-1037                                                                               Page 19 of 28
                                                                                  RFP —Attachment 2


        C.3.    Personnel
        At least two key personnel are required and shall be clearly indicated. Resume summaries for
        key personnel shall be included in this section, and full resumes in the appendix. The percentage
        of time each key person is proposed should be clearly indicated here. These percentages will be
        used in the evaluation of the cost proposals as well as to determine what the offeror see as the
        period of time needed to perform the required tasks.

D.      Experience and Past Performance (5 page limit)
Describe the teams overall experience with development, processes, and technologies similar to those
described in this solicitation. Clearly indicate which organization on your team is providing this
experience.

Provide a description of at least three projects successfully performed in the past that indicate the
ability to perform on this effort. At least one of these projects should have been performed for an
organization other than SAIC-F. Clearly indicate who on your team performed, what role was played on
each of these projects, and the success criteria that were used to judge the project. Summaries shall be
given here and more complete descriptions may be included in the appendix.

E.      Project Plan and Work Breakdown Structure (3 page limit)
Describe in summary form the set of tasks that will be performed in order to accomplish project
objectives.

Detail the methods for producing deliverables, allocation of technical staff, and other resources
necessary to produce deliverables, and timelines.

Provide a draft project plan in MS Project format as a separate attachment (no page limit). This
document should contain tasks that demonstrate how objectives described in the Statement of
Objectives will be accomplished. The draft project plan shall show tasks, dependences, and milestones,
any milestone reviews as requested in the RPF, as well as any requested Offeror-supplied dates for
deliverables.

F.      Management Approach (3 page limit)
        F.1.    Controls
        Describe your project management approach and what control mechanism you can put in place
        to track progress and ensure project schedules will be met in according to agreed-upon
        schedules.

        F.2.    Risk Management
        Describe your overall risk mitigation strategy.


RFP No. ST12-1037                                                                            Page 20 of 28
                                                                                      RFP —Attachment 2


        Provide an initial risk table. This table should include a list of project risks, an estimation of the
        severity of the risk (H,M,L), and a brief risk mitigation approach for that risk.

        F.3.    Subcontractor Management
        Describe management controls to be put in place for Subcontractor management if
        Subcontractors are a part of the proposed team.

        F.4.    Financial Tracking
        Describe the mechanism you will use to control budget and cost.

        F.5.    Appendix (no page limit)




RFP No. ST12-1037                                                                                 Page 21 of 28
Attachment 3: Cost (or Price) Proposal Information
Requirements




RFP No. ST12-1037                                    Page 22 of 28
                                                                                     RFP —Attachment 3


Cost (or Price) Proposal Information Requirements
Proposals which include unrealistic or unreasonable costs may be viewed as a failure to comprehend the
complexity of the technical requirements. Proposals shall therefore demonstrate a complete
understanding of the requirements and the associated complexities. Failure to adequately demonstrate
this understanding and establish realistic costs accordingly may result in a failure to be further
considered for award.

Information requested in this attachment is considered to be minimal and further information may be
required prior to award of any Agreement.

Specific Considerations:
A.      Section One – Cost (or Price) Proposal
The cost and price proposal shall contain sufficient information to allow SAIC-F to perform an analysis of
the proposed price of the work proposed. This information shall include the amounts of the basic
elements of the proposed overall prices including, but not limited to, labor hour and rates, travel,
materials, Subcontracts etc.

In preparing your cost proposal, the following shall be considered:

       Unit pricing will be provided in the tables with the technical proposal.

       Offeror is to prepare their cost and price proposal backup and submit with Offer in Microsoft
        Excel format.

       Offerors shall provide substantive detail regarding the price proposed so as to enable reviewers
        to objectively determine the reasonableness. Failure to provide a level of detail to facilitate this
        determination may result in the proposal being considered nonresponsive in the event an
        adequate number competitive proposals are not received.

B.      Section Two – Cost and Price Justification and Documentation
In this section, provide justifications and explanations of the proposed costs. This INCLUDES explanation
of the processes by which extended costs were derived and a basis for why the proposed costs should
be considered reasonable as backup for the cost evaluation. The supporting information to be provided
includes, but is not limited to:

       Labor costs. Provide labor categories and descriptions, if the proposed positions have not been
        filled or are to be named or hired, provide description of anticipated position and estimated
        labor category and rate for evaluation of costs.




RFP No. ST12-1037                                                                               Page 23 of 28
                                                                              RFP —Attachment 3


       Demonstration of the reasonableness of any proposed consultant or lower-tier Subcontractor
        consulting costs, including demonstration that the proposed rates/costs are in keeping with
        those normally charged for the work to be performed.




RFP No. ST12-1037                                                                       Page 24 of 28
Attachment 4: American Recovery and Reinvestment Act
Representations and Certifications




RFP No. 12ST1037                                       Page 25 of 28
                                                                                    RFP —Attachment XX


American Recovery and Reinvestment Act of 2009
Representations and Certifications
NOTICE: By signing below, the Subcontractor represents and certifies that this certification is accurate,
current, and complete and that the signer is duly authorized to make such certification on behalf of the
Subcontractor.
1.         Central Contractor Registration.
It   is,      is not registered in the Central Contractor Registration database.
2.         DUNS Number. (Show as it appears in CCR.)
Its DUNS number is            .
Its DUNS Plus 4 number is           or    a DUNS Plus 4 number is not applicable.
3.         Parent DUNS Number.
It   does,          does not have a parent company.
If it has a parent company, the parent company's DUNS number is as follows:           .
4.         NAICS Code of Work Performed.
Insert NAICS Code of Work Performed
5.         Legal Business Name. (Show as it appears in CCR.)
Its legal business name by which it is incorporated and pays taxes is


6.         Doing Business As (DBA). (Show as it appears in CCR.)
It   commonly uses another name,              does not commonly use another name.
If it commonly uses another name, the name is


7.         Subcontractor's Physical Address. (P.O. Box or c/o may not be used. Show as it appears in
           CCR.)
            Street Address:
            City:
            State:
            Zip Code (nine digits required)
            Congressional District (required if in
            U.S.)




RFP No. 12ST1037                                                                             Page 26 of 28
                                                                                 RFP —Attachment XX


8.      Primary Performance Location of the Work. (P.O. Box or c/o may not be used.)
         Street Address:
         City:
         State:
         Zip Code (nine digits required)
         Congressional District (required if in
         U.S.)
9.      Executive Compensation.
("Total Compensation" means the complete pay package of Subcontractor employees, including all
forms of monthly, benefits, services, and in-kind payments, consistent with the regulations of the
Securities and Exchange       Commission at 17 CFR 229.402.)
        A.         Names and total compensation of each of the five most highly compensated officers for
                   the calendar year in which the is awarded if—
                   1.     In its preceding fiscal year, it received—
                          a.      80 percent or more of its annual gross revenues in Federal contracts
                                  (and Subcontracts), loans, grants (and sub-grants), and cooperative
                                  agreements.
                          b.      $25,000,000 or more in annual gross revenues from Federal contracts
                                  (and Subcontracts), loans, grants (and sub-grants), and cooperative
                                  agreements.
                   2.     The public does not has access to information about the compensation of the
                          senior executives through periodic reports filed under section 13(a) or 15(d) of
                          the Securities Exchange Act of 1934 (15 U.S.C. 78M(a), 78o(d)) or section 6104
                          of the Internal Revenue Code of 1986.

                  Name                         Title                                Total Compensation




        The compensation for senior executives shown above is for calendar year Insert Year.

        Its fiscal year end date is Insert FY End Date.


RFP No. 12ST1037                                                                               Page 27 of 28
                                                                                      RFP —Attachment XX


          B.       If compensation of senior executives is not provided in 9.A. above, complete the
                   following:
          In its preceding fiscal year, it   did,      did not receive—

                   1.       80 percent or more of its annual gross revenues in Federal contracts (and
                            Agreements), loans, grants (and sub-grants), and cooperative agreements.
                   2.       $25,000,000 or more in annual gross revenues from Federal contracts (and
                            Agreements), loans, grants (and sub-grants), and cooperative agreements.
          The public     does,     does not have access to information about the compensation of the
          senior executives through periodic reports filed under section 13(a) or 15(d) of the Securities
          Exchange Act of 1934 {15 U.S.C. 78M(a), 78o(d)} or section 6104 of the Internal Revenue Code of
          1986.

          Legal Business Name:

10.       Gross Income.
Its gross income in the previous tax year           did,   did not exceed $300,000.
 By::
 Title:
 Signature:
 Date:




RFP No. 12ST1037                                                                               Page 28 of 28

								
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