; Integrating-Segmentation-Information-for-Improved-MRF-Based-Elastic-Image-Registration
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									                      PONDY IT
                         SOFT SOLUTIONS -PONDICHERRY
     Integrating Segmentation Information for Improved MRF-Based
                       Elastic Image Registration

we propose a method to exploit segmentation information for elastic image registration using a Markov-
random-field (MRF)-based objective function. MRFs are suitable for discrete labeling problems, and the
labels are defined as the joint occurrence of displacement fields (for registration) and segmentation
class probability. The data penalty is a combination of the image intensity (or gradient information) and
the mutual dependence of registration and segmentation information. The smoothness is a function of
the interaction between the defined labels. Since both terms are a function of registration and
segmentation labels, the overall objective function captures their mutual dependence. A multiscale
graph-cut approach is used to achieve subpixel registration and reduce the computation time. The user
defines the object to be registered in the floating image, which is rigidly registered before applying our
method. We test our method on synthetic image data sets with known levels of added noise and
simulated deformations, and also on natural and medical images. Compared with other registration
methods not using segmentation information, our proposed method exhibits greater robustness to
noise and improved registration accuracy.

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