lung by jianghongl

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									   Thorax / Lung




Basic Science Conference
        12/21/2005
      J.R. Nitzkorski
Sponsored by Joe
1. The most common cause of cancer death (US)
in men is:

1.   Prostate cancer
2.   Lung cancer
3.   Colorectal cancer
4.   Mesothelioma
5.   Leukemia
1. The most common cause of cancer death (US)
in men is:

1. Prostate cancer
2. Lung cancer
        Lung cancer death rate vastly surpasses that of
        other cancers in men, however reached a peak
        in 1990 and is trending downward
3. Colorectal cancer
4. Mesothelioma
5. Leukemia
2. The most common cause of cancer death (US)
in women is:

1.   Breast cancer
2.   Lung cancer
3.   Colorectal cancer
4.   Mesothelioma
5.   Leukemia
2. The most common cause of cancer death (US)
in women is:

1. Breast cancer
2. Lung cancer
          More women die from lung cancer than
          breast cancer, although breast cancer is more
          common than lung cancer. Heart disease
          remains the number one overall cause of
          death.
3. Colorectal cancer
4. Mesothelioma
5. Leukemia
3. Lung cancer develops in what percentage of
smokers

1.   20%
2.   40%
3.   60%
4.   80%
3. Lung cancer develops in what percentage of
smokers

1. 20%
        It also develops in some people with no exposure
        to cigarettes/occupational exposure, suggesting
        a genetic predisposition (especially in those less
        than 50)
2. 40%
3. 60%
4. 80%
4. The correct distribution of small cell lung cancer
(SCLC) to non-small cell lung cancer (NSCLC) is

1.   80 SCLC : 20 NSCLC
2.   50 SCLC : 50 NSCLC
3.   20 SCLC : 80 NSCLC
4.   10 SCLC : 90 NSCLC
5.   2 SCLC : 98 NSCLC
4. The correct distribution of small cell lung cancer
(SCLC) and non-small cell lung cancer (NSCLC) is

1. 80 SCLC : 20 NSCLC
2. 50 SCLC : 50 NSCLC
3. 20 SCLC : 80 NSCLC
      Although these represent two different histologic
      and clinical entities, some tumors have admixtures
      of cell types, suggesting a possible common origin
      for all lung cancers
4. 10 SCLC : 90 NSCLC
5. 2 SCLC : 98 NSCLC
5. Name the subdivisions of non-small cell lung
cancer (NSCLC):

1. _______________
2. _______________
3. _______________
5. Name the subdivisions of non-small cell lung
cancer (NSCLC):

1. Squamous cell
2. Adenocarcinoma
3. Large cell
6. Match the histologic cell type with the correct
frequency (%)

1.   Large cell            1.   31
2.   Adenocarcinoma        2.   29
3.   Squamous cell         3.   18
4.   Small cell            4.   9
6. Match the histologic cell type with the correct
frequency (%)

1.   Large cell            1.   31
2.   Adenocarcinoma        2.   29
3.   Squamous cell         3.   18
4.   Small cell            4.   9
7. Patient with a centrally located lung tumor is
most likely to have a:

1.   Adenocarcinoma
2.   Squamous cell
3.   Carcinoid
4.   Large cell carcinoma
7. Patient with a centrally located lung tumor is
most likely to have a:

1. Adenocarcinoma
2. Squamous cell
      Squamous cell carcinomas usually arise from the
      main, lobar, or segmental bronchi, however 1/3 can
      occur in the small bronchi of lung tissue.
      Symptoms = hemoptysis, atelectasis, post-
      obstructive pneumonia
      Diagnosis = bronchoscopy
3. Carcinoid
4. Large cell carcinoma
8. Patient with a peripherally located lung tumor is
most likely to have a:

1.   Adenocarcinoma
2.   Squamous cell
3.   Carcinoid
4.   Large cell carcinoma
8. Patient with a peripherally located lung tumor is
most likely to have a:

1. Adenocarcinoma
      Adenocarcinomas usually arise peripherally within
      the pulmonary parenchyma.
      Symptoms = pain related to invasion of chest wall,
      spine, brachial plexus.
      Diagnosis = percutaneous
2. Squamous cell
3. Carcinoid
4. Large cell carcinoma
9. Regarding NSCLC, the percentage of patients
who present with disseminated disease is _____%

Of those without disseminated disease, the
percentage of patients who present with locally
advanced / unresectable cancer is _____%
9. Regarding NSCLC, the percentage of patients
who present with disseminated disease is 50%

Of those without disseminated disease, the
percentage of patients who present with locally
advanced / unresectable cancer is 20%
10. Surgery is generally the accepted treatment
for NSCLC with the following stages (more than 1)

1.   Stage Ia and b
2.   Stage IIa
3.   Stage IIb
4.   Stage IIIa
5.   Stage IIIb
6.   Stage IV
10. Surgery is generally the accepted treatment
for NSCLC with the following stages (more than 1)

1. Stage Ia and b - surgery
2. Stage IIa - surgery
3. Stage IIb - surgery
4. Stage IIIa – surgery, usually after
   chemo/xrt
5. Stage IIIb – chemo/xrt, poss surgery
   after chemo/xrt
6. Stage IV - chemo
• For
  reference:
11. On CT, a lymph node _____ cm or less is
usually considered to be benign, whereas a lymph
node greater than _____ cm is usually considered
to be malignant
11. On CT, a lymph node 1.0 cm or less is usually
considered to be benign, whereas a lymph node
greater than 1.5 cm is usually considered to be
malignant**

**Co-morbid pulmonary disease and/or post-
obsructive pneumonia may cause significant
lymphadenopathy without metastasis
12. False-positive lymph node detection on FDG-
PET scanning commonly results from:

1. ________________________
2. ________________________
12. False-positive lymph node detection on FDG-
PET scanning commonly results from:

1. Granulomatous disease
2. Histoplasmosis
13. The modality of choice to confirm FDG-PET
positive mediastinal lymphadenopathy with a
tissue diagnosis:

1. ________________________
13. The modality of choice to confirm FDG-PET
positive mediastinal lymphadenopathy with a
tissue diagnosis:

1. Mediastinoscopy

								
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