Other Brain Nutrients:
What’s in O3 Balance Brain Lipid Repair Formula?
A number of studies have shown that the human brain begins to gradually lose its lipids starting around age 23 and that the loss accelerates considerably beginning at the age of 80. The greatest loss of these essential brain lipids occurs in the temporal lobes of the brain, followed closely by the frontal lobes, both essential for memory and learning. These lipids are vital for the operation of neuron cell membranes, especially the membranes of the dendrites and synapses, the main connections between brain cells. The makeup of brain cell membranes has been shown to be essential and many of the fats in the average Western diet are of the type that impairs brain cell membrane function. These lipids control the fluid quality of the membranes (called fluidity). Bad fats, such as the omega-6 fats, trans fats, and less so, saturated fats, interfere with this fluidity while good fats, such as DHA improve it. Special types of fats, called phospholipids, also function as sources of some neurotransmitters and cell signaling messenger molecules important for brain cell function. Strokes, brain injury, chronic brain inflammation, and chronic brain diseases can result in a rapid decline of these essential lipids. A number of studies have shown that feeding these lipids as supplements can significantly improve recovery and neurologic function. They also play a special and essential role in memory and learning.
Phosphotidylcholine: This is one of the most abundant phospholipids in the brain. It not only makes up the bulk of the membrane’s lipid structure, but also is vital for the formation of the neurotransmitter acetylcholine, which is strongly associated with memory and learning. There is a constant turnover in this phospholipid, especially with injury and disease. Feeding phosphotidylcholine to patients with brain injuries and strokes has been shown, in some studies, to not only speed up their recovery, but to make their recovery more complete. It is especially important for the developing brain. Phosphotidylethanolamine: This is another phospholipid found in the brain and is important for brain cell membranes and synaptic connections which allow brain cells to communicate. Studies have shown that as we age the level of phosphotidylethanolamine decreases in the brain and supplementing with this phospholipid can improve memory and reduce depression. Phosphotidylinositol: This brain phospholipid is also vital to proper brain function and becomes depleted with aging, injury, strokes, and with neurodegenerative diseases. It also plays a very important role in some of the brain’s most complex functions, especially behavior and memory. For instance, low levels in children are characteristic of ADHD. Phosphotidylserine: This phospholipid has gained a lot of attention because of its association with memory and learning. Several studies using animal models have shown that phosphotidylserine supplementation can increase learning and memory. Human studies have also demonstrated improved memory with supplementation. In men, this phospholipid has also been shown to improve testosterone levels, which helps protect the brain. Testosterone levels tend to fall rather drastically with aging and some studies link this fall to increasing difficulties with memory. Mixed Tocopherols (D-alpha-tocopherol & D-gamma-tocopherol): The natural tocopherols, better known as vitamin E, play a vital role in protecting the brain lipids from oxidation (called lipid peroxidation). Because vitamin E is lipid soluble, all of its components are dissolved in the phospholipids, preventing them from oxidizing. The gamma-tocopherol also powerfully inhibits brain inflammation. Tocotrienols: These are also in the vitamin E group and have been shown to have even a more powerful ability to inhibit phospholipid oxidation. Together with the tocopherols, they provide the highest levels of brain protection against lipid peroxidation. Ultra-Pure DHA/EPA: Many omega-3 oil products contain a mixture of DHA and EPA that provides the brain with the improper ratio of N-3 lipids. That is, they have far too high a level of EPA which can cause immune suppression and bleeding risk. The brain mainly uses DHA which is critical to brain development, brain plasticity (growth and repair), and neurotransmitter function. The oil is highly purified to remove toxic metals, pesticides, and industrial chemicals.
Curcumin: This flavonoid, extracted from the spice turmeric, is being shown to be a leader in brain protection. It is a very powerful anti-inflammatory, a potent and versatile antioxidant, and prevents many of the changes seen with Alzheimer’s disease. Extensive research is now being conducted to see if it can prevent Alzheimer’s disease in humans. Because all neurodegenerative diseases are caused by chronic brain inflammation, it holds great promise in all inflammation-related neurological disorders. Curcumin is best absorbed when dissolved in oil, which makes this capsule superior to other forms of curcumin. Ginger: Ginger extract is also a potent anti-inflammatory. In addition, it reduces stomach irritation. Quercetin: Like curcumin, quercetin is a powerful antiinflammatory and versatile antioxidant. It also prevents lipid peroxidation, thus protecting delicate brain membranes and connections. There is also evidence that quercetin, found commonly in fruits and vegetables, may block the damage associated with Alzheimer’s disease. Recent studies have shown that it is much more effective in protecting DNA and other critical cell structures than is vitamin C. CoQ10: A small amount of CoQ10 was also added to synergistically enhance the protection of brain cells and to enhance cell energy production.
in life. Likewise, a number of studies have shown that vitamin B12 levels are universally low in those with Alzheimer’s disease; much lower than we see in normal elderly. The body uses a form called methylcobalamin, as is used in my supplement. Many supplements use a form called cyanocobalamin, which is bound with the powerful poison-cyanide. The brain poorly utilizes cyanocobalamin.
Special Brain Protectants
Carnosine: This is a compound found naturally in the body and is known to play a vital role in a number of organs, especially the brain. Studies have shown that it can: dramatically reduce seizures; prevent oxidative damage to the brain; neutralize one of the most commonly found lipid peroxidation products (4-HNE), normally found in very high concentrations in neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s dementia; prevent zinc damage to brain cells; prevent DNA and protein crosslinking, something commonly seen in neurodegenerative diseases; reduce glycation, and directly protect against excitotoxicity. Recent studies have shown significant improvement when used in cases of autism. It has a very high safety profile. Acetyl-L Carnitine: This naturally occurring compound has been shown to nurture the brain, raise the level of the neurotransmitter acetylcholine in the brain, promote brain fiber growth, and protect against excitotoxicity. It also improves brain cell energy levels which protect against excitotoxicity. A number of studies have also shown benefit in reducing the pain associated with diabetic neuropathy and in reducing depression. Like carnosine, it has a very high margin of safety. Trans-Ferulic Acid: This is a natural substance found in many fruits. Many studies have found a cancer inhibiting effect for trans-ferulic acid. More recent studies have shown that taking trans-ferulic acid over a long period of time significantly protects the brain against excitotoxicity and microglial activation, both central mechanisms in the production of a great number of neurological diseases. In one animal study it was shown to reduce the buildup of dangerous amyloid plaque, associated with Alzheimer’s disease. Trans-Resveratrol: This is a natural compound found in a number of foods, with the highest levels being found in the skin of grapes. Grapes grown in higher altitudes have higher levels of this powerful flavonoid. A great number of studies have shown that trans-resveratrol has powerful anti-cancer effects, but of growing interest is the finding of equally powerful brain protecting properties. This compound has been shown to reduce brain inflammation by suppressing microglial activation and inhibiting inflammatory biochemical pathways in cells. It also reduces the changes seen in the Alzheimer’s brain, such as a buildup of beta-amyloid. Of real interest is the discovery that resveratrol, when fed to rats on a high calorie diet, provides the same level of protection we see with low-calorie diets. High calorie diets drastically increase one’s risk of Alzheimer’s disease and low-calorie diets are protective. White Tea Extract: A number of studies have shown that green tea extract can reduce one’s risk of several forms of cancer, reduce inflammation, protect against excitotoxicity, and suppress excessive brain microglial activation, all things that protect the brain. The compounds in green tea, called catechins, include epigallocatechin galate (ECGC), epicatechin gallate (ECg), epicatechin (EC), and a number of other compounds, the most effective being EGCG. White
O3 Balance Brain Repair Formula Brain Energy Enhancement
One of the most common effects of brain injury, strokes, or age-related neurodegenerative disorders is a loss of brain cell energy production. This can occur decades before neurological signs and symptoms appear. It has also been shown that improving brain cell energy production greatly reduces the damage by protecting the brain from excitotoxicity, a major cause for the damage. This supplement was designed to use a number of metabolic stimulants to prevent a loss of brain cell energy production. These are the main ingredients that accomplish that goal.
Vitamin K: Most of us are familiar with vitamin K playing a role in blood clotting. What is less well known by the lay public is that it also plays a critical role in energy production by cells, especially brain cells. In fact, it is part of a number of nutrients that are used to treat mitochondrial diseases in which there are severe deficiencies in brain cell energy production. Most neurodegenerative diseases of aging, such as Alzheimer’s dementia and Parkinson’s disease, are characterized by defective brain energy production, which often occurs decades before symptoms develop. In addition, low brain cell energy levels dramatically increase damage by excitotoxicity, the major mechanism of damage in these disorders. Thiamine (Vitamin B1): People suffering from dementia and other impairments of mental ability often have low levels of this vital energy vitamin. For example, alcoholics have very low brain thiamine levels which can result in severe dementia and replacing this vitamin can reverse this dementia. Deficiencies, even subclinical ones, can increase sensitivity to excitotoxicity. Riboflavin (as Riboflavin-5 phosphate): This is also one of the energy-controlling B vitamins and, like thiamine, helps protect the brain from energy failure and excitotoxicity. The body uses the metabolic form, called riboflavin-5 phosphate, which is used in this supplement. People with chronic diseases and many older people cannot properly utilize riboflavin itself and require the metabolic form-riboflavin-5 phosphate. Vitamin B6 (as Pyridoxal-5 phosphate): This B vitamin not only plays a role in energy production by brain cells, but also regulates the production of a number of neurotransmitters and lowers elevated levels of glutamate, the powerful excitotoxin. Again, it is in the form used by the brain so as to maximize its effectiveness. Niacinamide: This B vitamin also plays a role in brain cell energy production and plays a role in regulating the brain’s level of the neurotransmitter serotonin, which is critical in preventing depression, anxiety, and anger. In this form it does not cause the itching or liver damage associated with higher doses of niacin. Folinic Acid: You may know this vitamin better by its other form – folic acid. In the form used in my supplement, it has the highest absorption and utilization by the brain. This B vitamin is also used in a great number of biochemical reactions in cells, the most important of which is methylation reactions. These reactions play a critical role in DNA repair and in lowering homocysteine, a powerful excitotoxin. Levels of this vitamin frequently fall with aging and can be quite low in the elderly. Vitamin B12 (as methylcobalamin): Several studies have shown that both folic acid and vitamin B12 are frequently low in the elderly and that these two vitamins may begin to fall much earlier
tea has much higher concentrations of these protective compounds than does green tea. White tea also has the advantage of having much lower levels of harmful fluoride and aluminum than green tea. Milk Thistle Extract (Silymarin and Silybin): You may be aware that milk thistle extract has been shown to powerfully protect the liver from a number of toxins and to promote detoxification and liver healing. Of equal importance is the finding that silymarin and silybin are powerful protectors of the brain, even in low concentrations. In fact, silymarin has been shown to suppress overactive microglial in the brain, even when given in relatively low concentrations. The combined benefit of improved liver health, enhanced detoxification ability, antioxidant effects, and reduced brain inflammation makes this component of the formula very beneficial for brain health. Curcumin: This flavonoid ingredient is being shown to be one of the most powerful brain protectants now known. Not only does curcumin prevent a great number of cancers, but it also protects mice genetically prone to Alzheimer’s-like disease from ever developing the disorder and may do the same thing in humans. Studies are now being conducted to see if it will. One of the ways curcumin protects the brain is by powerfully suppressing inflammation. In fact, it is one of the most powerful anti-inflammatory flavonoids known and it also suppresses brain microglial hyperactivity and blocks excitotoxicity in the brain. Hesperidin: This is also a naturally occurring flavonoid found in many citrus fruits. Like curcumin, it reduces inflammation in the brain and protects brain cells and their connections. It also powerfully increases the strength of blood vessels in the brain, which help protect against aneurysms, strokes, and brain hemorrhages. Hesperidin has been shown to prevent bone loss, lower cholesterol, and even lower elevated blood pressure in animal studies. It also calms anxiety and kills harmful germs. Also important to good brain health is the finding that it improves glucose control, that is, it prevents insulin resistance. R-Lipoid Acid: This is a naturally occurring compound found in every cell in the body and is considered one of the most important antioxidants in cells. It is unique in that it regenerates other antioxidants, such as vitamin E and C when they are oxidized. It also increases the cell’s level of another very important antioxidant called glutathione. In addition, R-lipoic acid increases the cell’s energy level and protects the brain against mercury poisoning. The R-form of lipoic acid is the most potent. CDP-Choline: This is a natural compound used by the brain in producing important brain lipids called phosphatides. Several studies in both humans and animals have shown benefit in cases of strokes and age-related memory loss. Animal studies have shown that mice raised without the stimulation of good surroundings (impoverished) improved to normal if given CDP-choline. The beneficial effects of this compound on the brain are many and include an increase in brain choline (needed to make the memory-related neurotransmitter, acetylcholine), increased synthesis of phosphotidylcholine, and suppression of a number of reactions harmful to brain cells. Excitotoxicity is known to dramatically lower brain choline levels and damage cell membranes. CDP-choline has been shown to repair the damage to the cell membrane, which is essential for normal brain function. Stroke studies in animals, in which strokes are intentionally induced, have shown that those receiving CDP-choline have much smaller strokes as well as better and faster neurological recovery. Some human studies have shown the same effectiveness.
Everything you need to know about 03 Balance Brain Repair Formula
03 Balance Brain Repair Formula
The powerful, anti-inflammatory supplements used in newly developed O3 Balance Brain Repair Formula, when combined with a brain healthy diet, will maximize the brain’s ability to heal and reduce inflammation (a central mechanism of devastating neurological disorders). The nutrients in 03 Balance Brain Repair Formula are known to promote the repair of brain cells and their connections, called synapses. Reducing chronic inflammation also reduces both the risk of brain degeneration and suppresses the central mechanism of neurodegeneration. The formula also includes a number of nutrients that have been shown to aid in the repair of damaged brain cells, such as: specific phospholipids, antioxidants, vitamins and special brain metabolic PRICE stimulants. Also included are a mixture of nutrients GUARA known to promote DNA Repair, since damage to DNA If you can buy NTEE ALL of the ingredients is widespread in all neurodegenerative disorders. in for less, sho O3 Balance There are a great number of products promoted as receipt of pu w us your rc we will give hase and ‘brain boosters’ or ‘memory boosters’. While some have FREE 1 year you a supply! ingredients that have shown benefits, the concentrations Go to 1800sp ec for more info ial.com rmation are either too low or in forms that are not adequately utilized by the brain.
The product names used in this publication are for identification purposes only. All trademarks and registered trademarks are the property of their respective owners. Published by Newport Nutritionals, 660 Newport Center Drive #700, Newport Beach, CA 92660
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Why should I be worried about Brain Health at my age?
About Dr. Russell Blaylock, MD, CCN. Dr. Blaylock was a practicing neurosurgeon for 24 years, after which he retired to devote full time to writing, lecturing and research. He attended Louisiana State University School of Medicine in New Orleans, Louisiana and completed his surgical internship and neurosurgical residency at the Medical University of South Carolina. He trained with the esteemed neurosurgeon, Dr. Ludwig Kempe and developed a lifelong friendship with this world famous teacher and neurosurgeon. Dr. Blaylock has published over 35 papers in scientific and lay journals and wrote three books on health and nutrition. He also wrote and illustrated a patient care manual on multiple sclerosis, lectured extensively in the United States and has appeared on nationally syndicated radio and television programs. In addition he writes an international best-selling wellness newsletter. Dr. Blaylock serves on the Scientific Advisory Board of the Life Extension Foundation as an editor for the Journal of American Physicians and Surgeons, is on the editorial staff of the Journal of the American Nutriceutical Association and the journal Fluoride, the official quarterly journal of the International Society for Fluoride Research. He is the 2004 recipient of the Integrity in Science Award by the Westin A. Price Foundation. At present he serves as a lecturer on the staff of the Fellowship for Anti-aging and Regenerative Medicine and is a Visiting Professor of Biology at Belhaven College in Jackson, Mississippi.
Compelling research now confirms that most diseases begin very early in life, even during childhood. This is true for atherosclerosis. A buildup of plaque on the arteries feeding the brain can lead to strokes or vascular dementia. Likewise, recent research indicates that not only are the number of neurodegenerative diseases increasing, but they are occurring at a much younger age, even in the early twenties and thirties. Incredibly, Alzheimer’s disease and Parkinson’s disease are also increasing dramatically at younger ages. What you do now can mean the difference between a full, happy, and productive life with your family or a life of disability and misery.
Why are there two capsules with different dosages?
Each of the capsules contains specific products that are designed for maximum absorption, not only from the gut, but also into the brain, and this is critical. The capsules are designed to give you the most effective dosage of each ingredient and in a capsule system that ensures absorption. One nutrient formula is delivered in a Caplique™, with the essential daily nutrients suspended in High DHA Omega 3 oil,maximizing synergistic potential and absorption. The other nutrient formula is delivered in a water soluble vegetarian capsule which facilitates intestinal absorption.
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Is there any proof that the ingredients included in the Blaylock O3 Balance Brain Repair Formula actually work?
All of the ingredients have been tested in a number of ways. Some of the ingredients are now showing great promise in preventing and treating neurodegenerative diseases such as Alzheimer’s dementia and Parkinson’s disease and undergoing further extensive testing. All of these ingredients are present in a number of foods consumed by people every day. The difference is that in the 03 Balance Brain Formula these ingredients have been highly purified and concentrated to protect and heal the brain. Dr. Blaylock’s full clinical research references are listed on the Newport Nutritionals website:
always in doses far too low to have any effect. Some of these products will brag about having as many as 50 nutrients in them. The doses in these products are incredibly small. There are also problems with the quality of the ingredients, absorption problems, and difficulties with the form of the ingredients used.
Why do you use both Vegetarian Capsules & Fish Gelatin Capliques™?
Can I do anything else to improve my Brain Health?
Why should I pay more for O3 Balance Brain Repair Formula, when I can purchase cheap brain formulas at a market or pharmacy?
Why is the Omega 3 oil in O3 Balance Brain Repair Formula high in DHA?
Why should I take O3 Balance Brain Repair Formula?
Most of us, according to nutritional research, are deficient in a number of vitamins, minerals, and special fats needed for good brain health. Most of us lead busy, stressful, and hurried lives that leave us little time to prepare and eat healthy diets. Studies have shown that not only do nutritional deficiencies get worse with aging, severe deficiencies are occurring in the young. 03 Balance Brain Repair Formula provides you with the missing nutrition known to be essential to good brain health. There is also compelling evidence that one of the primary reasons for brain degeneration is chronic inflammation in the body, something commonly caused by a poor diet, stress, and obesity. 03 Balance Brain Repair Formula contains a special blend of nutrients that have been shown to reduce brain inflammation and promote brain healing.
O3 Balance Brain Repair Formula is manufactured in the United States. The manufacturer holds a pharmaceutical-grade license - the highest license attainable by a supplement manufacturer. For my O3 Balance Brain Repair Formula, I specifically chose pharmaceutical grade nutrients of the highest quality and bioavailability. Each bottle of my Brain Formula is made from the freshest ingredients obtainable and has been extensively tested for purity by independent laboratories. Most importantly, my product is manufactured approximately every 30 days. This is done to make sure that the O3 Balance Brain Repair Formula you receive will be at its optimum potency and freshness.
The omega-3 oils play a vital role in brain development and brain health in babies, children, and adults. Omega-3 oils are composed of two functional components called EPA and DHA. Of the two, DHA plays the major role in brain health. In fact, the majority of omega-3 oil components in the human brain are DHA. The major complication of omgea-3 oils, immune suppression, bleeding tendencies, and a loss of control of diabetes is attributed to the EPA portion. Recent studies show that EPA, not DHA, can oxidize in the body, causing damage to cells, especially brain cells. It is difficult to find omega-3 oils with a high DHA and low EPA content. But I have formulated a pharmaceutical grade high DHA oil for my 03 Balance Brain Repair Formula, and it is guaranteed to be free of all contaminants such as mercury, pesticides, and industrial chemicals.
Encapsulation of products is a real science and we have benefited from the latest of technologies. Because of the real danger of mad cow disease (prion diseases) with bovine gelatin capsules, I have chosen to use special capsules made from purified fish gelatin and vegetable gelatin. The caplique™ is a unique way to encapsulate my High DHA Omega3 oil, which improves safety and absorption. The other nutrient formula is delivered in a water soluble vegetarian capsule which facilitates intestinal absorption.
How long do I have to take O3 Balance Brain Repair Formula?
What most studies have shown is that the benefits of brain supplementation occur soon after taking the supplements, but that continuous maintenance is needed to keep the brain healthy. This is because the brain has a very high turnover of these nutrients and has one of the highest metabolic rates of any organ in the body. In essence, to keep the brain working at peak performance one needs to continuously supply it with these nutrients. Likewise, because brain inflammation is always occurring, the antiinflammatory nutrients are needed on a continuous basis as well.
There are a number of things that a person can do to improve brain health. For example, it is known that regular, moderate exercise can significantly improve memory and thinking ability. Fasting once a week has also been shown to improve memory and thinking ability in animals, for the same reasons as exercise; they both increase brain cell repair hormones called neurotrophic factors. We also know that reducing calories, especially those from sugar and highly processed carbohydrates, can improve brain function and prevent brain aging changes. Finally, we have a principle called “use it or lose it.” Like muscles, the brain will atrophy (shrink) if it is not used. This can include working puzzles, reading material that requires attention and deep thinking, learning a new language, reading books upside down, or taking adult courses in new subjects. Often, we become lazy thinkers, doing things by repetition and utilizing notes and lists rather than memorizing material. This makes our brains lazy and encourages brain aging.
Why is the Blaylock O3 Balance Brain Repair Formula better than other brain formulas?
Because of the drastic rise in neurological disease such as Alzheimer’s dementia, Vascular dementia, Parkinson’s disease, Lou Gehrig’s disease (ALS), and agerelated memory loss, there have appeared a great number of products claiming they boost brain health, memory, or prevent brain aging. Some of these products do contain good ingredients. Unfortunately, most contain a lot of products of marginal benefit and almost