factor of activated T cells

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					    Supplementary Table. Genes present 2 fold expression changes by ST7-1a expression in PC-3 cells


AffyID                                                                                                             Fold      S.D†
                                                                                                                                     GO Biological Process   §

              Gene Name                                                                             Gene Symbol
                                                                                                                   change‡
202627_s_at
              serine (or cysteine) proteinase inhibitor                                             SERPINE1       24.99     20.04   blood coagulation
202628_s_at
230861_at     DKFZP434L187 protein                                                                  DKFZP434L187   15.10     13.41   unknown
205625_s_at   calbindin 1                                                                           CALB1          11.28     6.20    unknown
203828_s_at   interleukin 32                                                                        IL32           6.47      1.30    immune response / cell adhesion
232231_at     runt-related transcription factor 2                                                   RUNX2          6.29      1.99    ossification / transcription / regulation of transcription, DNA-dependent
                                                                                                                                     immune response / signal transduction / cell-cell signaling / positive regulation
205992_s_at   interleukin 15                                                                        IL15           5.31      1.98
                                                                                                                                     of cell proliferation
                                                                                                                                     embryonic development (sensu Mammalia) / N-glycan processing /
236835_at     fucosyltransferase 8 (alpha (1,6) fucosyltransferase)                                 FUT8           4.75      1.95
                                                                                                                                     oligosaccharide biosynthesis / L-fucose catabolism
201578_at     podocalyxin-like                                                                      PODXL          4.71      2.05    unknown
202672_s_at   activating transcription factor 3                                                     ATF3           4.60      2.77    transcription / regulation of transcription, DNA-dependent
226869_at     Full length insert cDNA clone ZD77F06                                                 unknown        4.44      2.81    unknown
229641_at     hypothetical protein FLJ25224                                                         unknown        4.38      1.05    unknown
205016_at     transforming growth factor, alpha                                                     TGFA           4.32      1.95    regulation of cell cycle / cell-cell signaling / cell proliferation
216250_s_at   leupaxin                                                                              LPXN           4.22      1.54    protein complex assembly / cell adhesion / signal transduction
242229_at     N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D                           NAPE-PLD       4.11      1.02    unknown
228977_at     Interleukin 17D                                                                       IL17D          4.08      1.95    inflammatory response
205798_at                                                                                                                            regulation of DNA recombination / immune response / cell surface receptor
              interleukin 7 receptor                                                                IL7R           4.07      1.19
226218_at                                                                                                                            linked signal transduction / antimicrobial humoral response (sensu Vertebrata)
                                                                                                    KRTAP2-1
1555673_at    keratin associated protein 2-1 / keratin associated protein 2-4                                      4.03      2.17    unknown
                                                                                                    KRTAP2-4
212092_at     paternally expressed 10                                                               PEG10          3.99      1.43    unknown
226142_at     GLI pathogenesis-related 1 (glioma)                                                   GLIPR1         3.68      0.71    unknown
              a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1
237411_at                                                                                           ADAMTS6        3.60      1.99    proteolysis and peptidolysis
              motif, 6
202016_at     mesoderm specific transcript homolog (mouse)                                          MEST           3.59      1.06    mesoderm development
                                                                                                                                     protein complex assembly / cell motility / actin polymerization and/or
205809_s_at   Wiskott-Aldrich syndrome-like                                                         WASL           3.39      1.03
                                                                                                                                     depolymerization
203691_at
              protease inhibitor 3, skin-derived                                                    PI3            3.37      1.21    copulation
41469_at
226810_at     Chromosome 6 open reading frame 155                                                   C6orf155       3.35      1.12    unknown
209129_at     thyroid hormone receptor interactor 6                                                 TRIP6          3.34      1.11    unknown
240105_at     Chromosome 21 open reading frame 66                           C21orf66   3.33   1.06   transcription / regulation of transcription, DNA-dependent
1555292_at    family with sequence similarity 40, member B                  FAM40B     3.29   0.62   unknown

201539_s_at
210298_x_at
              four and a half LIM domains 1                                 FHL1       3.27   0.56   muscle development / cell growth / cell differentiation
210299_s_at
214505_s_at

235046_at     Transcribed locus                                             unknown    3.27   1.11   unknown
244534_at     Zuotin related factor 1                                       ZRF1       3.25   0.63   protein folding / protein folding / regulation of transcription
205192_at     mitogen-activated protein kinase kinase kinase 14             MAP3K14    3.22   1.41   protein amino acid phosphorylation
232137_at     zinc finger protein 616                                       ZNF616     3.20   0.70   unknown
220117_at     zinc finger protein 659                                       ZNF659     3.15   0.72   unknown
226576_at     Rho GTPase activating protein 26                              ARHGAP26   3.12   0.93   neurogenesis / actin cytoskeleton organization and biogenesis
219884_at     LIM homeobox 6                                                LHX6       3.10   0.74   regulation of transcription, DNA-dependent / brain development
226136_at     unknown                                                       unknown    3.09   0.71   unknown
202145_at     lymphocyte antigen 6 complex, locus E                         LY6E       3.08   0.48   defense response / cell surface receptor linked signal transduction
223500_at     complexin 1                                                   CPLX1      3.06   1.22   neurotransmitter transport / exocytosis / synaptic transmission
227152_at     hypothetical protein FLJ10652                                 FLJ10652   3.01   0.77   unknown
209369_at     annexin A3                                                    ANXA3      3.01   0.46   unknown
207826_s_at   inhibitor of DNA binding 3                                    ID3        2.98   0.90   development / regulation of transcription
224873_s_at   mitochondrial ribosomal protein S25                           MRPS25     2.87   0.59   protein biosynthesis
217624_at     PDGFA associated protein 1                                    PDAP1      2.87   0.72   signal transduction / cell proliferation
                                                                                                     MAPKKK cascade / anti-apoptosis / defense response / transmembrane
                                                                                                     Receptor protein tyrosine kinase signaling pathway / JAK-STAT cascade /
243541_at     interleukin 31 receptor A                                     IL31RA     2.83   0.56
                                                                                                     Positive regulation of cell proliferation / cytokine and chemokine mediated
                                                                                                     Signalling pathway
                                                                                                     transcription / regulation of transcription, DNA-dependent / ubiquitin cycle /
201867_s_at   transducin (beta)-like 1X-linked                              TBL1X      2.79   0.65
                                                                                                     signal transduction / visual perception / perception of sound
                                                                                                     negative regulation of transcription from RNA polymerase II promoter /
213139_at     snail homolog 2 (Drosophila)                                  SNAI2      2.75   0.47   transcription / regulation of transcription, DNA-dependent / development /
                                                                                                     ectoderm and mesoderm interaction / perception of sound
205768_s_at   solute carrier family 27 (fatty acid transporter), member 2   SLC27A2    2.74   0.45   very-long-chain fatty acid metabolism / lipid metabolism / metabolism
229194_at
              polycomb group ring finger 5                                  PCGF5      2.71   0.64   protein ubiquitination
235331_x_at
207876_s_at   filamin C, gamma (actin binding protein 280)                  FLNC       2.71   0.41   unknown
210310_s_at                                                                                                   regulation of cell cycle / cell-cell signaling / neurogenesis / cell proliferation /
              fibroblast growth factor 5                                         FGF5           2.68   0.48
210311_at                                                                                                     fibroblast growth factor receptor signaling pathway
                                                                                                              transcription / regulation of transcription from RNA polymerase II promoter /
207678_s_at   SRY (sex determining region Y)-box 30                              SOX30          2.68   0.89
                                                                                                              spermatogenesis
209254_at
              KIAA0265 protein                                                   KIAA0265       2.68   0.94   unknown
209256_s_at
227828_s_at   hypothetical protein FLJ13391                                      FLJ13391       2.67   0.46   unknown
219936_s_at   G protein-coupled receptor 87                                      GPR87          2.67   0.52   signal transduction / G-protein coupled receptor protein signaling pathway
227340_s_at
              RGM domain family, member B                                        RGMB           2.67   0.96   unknown
242450_at
                                                                                                              calcium ion sensing / transport / synaptic transmission / neurotransmitter
203998_s_at   synaptotagmin I                                                    SYT1           2.66   0.54
                                                                                                               secretion / regulation of exocytosis / protein homooligomerization
235852_at     Stonin 2                                                           STN2           2.64   0.48   intracellular protein transport / regulation of endocytosis
231963_at     Homo sapiens, clone IMAGE:3869276, mRNA                            unknown        2.64   0.66   unknown
213094_at     G protein-coupled receptor 126                                     GPR126         2.62   0.24   signal transduction / neuropeptide signaling pathway
221765_at     UDP-glucose ceramide glucosyltransferase                           UGCG           2.62   0.45   carbohydrate metabolism / protein amino acid N-linked glycosylation
212207_at     thyroid hormone receptor associated protein 2                      THRAP2         2.62   0.14   unknown
239265_at     transmembrane protein 20                                           TMEM20         2.59   0.42   unknown
223465_at     collagen, type IV, alpha 3 (Goodpasture antigen) binding protein   COL4A3BP       2.56   0.16   protein amino acid phosphorylation / immune response
47069_at      proline rich protein 5                                             PRR5           2.56   0.43   unknown
209270_at     laminin, beta 3                                                    LAMB3          2.56   0.50   cell adhesion / epidermis development
204863_s_at   interleukin 6 signal transducer (gp130, oncostatin M receptor)     IL6ST          2.55   0.57   immune response / cell surface receptor linked signal transduction
                                                                                                              nucleobase, nucleoside, nucleotide and nucleic acid metabolism / cytidine
205627_at     cytidine deaminase                                                 CDA            2.55   0.09
                                                                                                              metabolism
                                                                                                              asparagine biosynthesis / glutamine metabolism / metabolism / amino acid
205047_s_at   asparagine synthetase                                              ASNS           2.54   0.31
                                                                                                              biosynthesis
222666_s_at   RNA terminal phosphate cyclase-like 1                              RCL1           2.53   0.31   unknown
226402_at     cytochrome P450, family 2, subfamily U, polypeptide 1              CYP2U1         2.52   0.15   electron transport
238609_at     hypothetical protein DKFZp727G131                                  DKFZp727G131   2.51   0.32   unknown
235736_at     Homo sapiens, clone IMAGE:5167600, mRNA                            unknown        2.49   0.53   unknown
218893_at     isochorismatase domain containing 2                                ISOC2          2.49   0.41   metabolism
231841_s_at   KIAA1462                                                           KIAA1462       2.48   0.57   unknown
207172_s_at
              cadherin 11, type 2, OB-cadherin (osteoblast)                      CDH11          2.47   0.50   ossification / homophilic cell adhesion / homophilic cell adhesion
207173_x_at
219582_at
               opioid growth factor receptor-like 1                                  OGFRL1          2.45   0.23   unknown
238469_at
228045_at      MRNA; cDNA DKFZp451K063 (from clone DKFZp451K063)                     unknown         2.45   0.40   unknown
43427_at       acetyl-Coenzyme A carboxylase beta                                    ACACB           2.40   0.12   fatty acid biosynthesis / metabolism
218564_at      ring finger and WD repeat domain 3                                    RFWD3           2.39   0.61   protein ubiquitination
212318_at
               transportin 3                                                         TNPO3           2.38   0.17   protein transport
214550_s_at
225173_at      Rho GTPase activating protein 18                                      ARHGAP18        2.38   0.40   unknown
1562527_at     hypothetical protein LOC283027                                        LOC283027       2.37   0.27   unknown
1556220_at     unknown                                                               unknown         2.35   0.38   unknown
212570_at      KIAA0830 protein                                                      KIAA0830        2.34   0.15   unknown
225942_at      neurolysin (metallopeptidase M3 family)                               NLN             2.31   0.16   proteolysis and peptidolysis
                                                                                                                   electron transport / 'de novo' pyrimidine base biosynthesis / uracil catabolism /
204646_at      dihydropyrimidine dehydrogenase                                       DPYD            2.31   0.28
                                                                                                                   thymidine catabolism
238066_at      retinol binding protein 7, cellular                                   RBP7            2.29   0.23   transport
1554132_a_at   KIAA1128                                                              KIAA1128        2.27   0.21   unknown
234726_s_at    hypothetical protein FLJ13576                                         FLJ13576        2.25   0.24   unknown
227371_at      BAI1-associated protein 2-like 1                                      BAIAP2L1        2.23   0.18   unknown
226434_at      hypothetical protein MGC22793                                         MGC22793        2.22   0.15   unknown
212814_at      KIAA0828 protein                                                      KIAA0828        2.21   0.17   one-carbon compound metabolism
                                                                                                                   striated muscle contraction / perception of sound / actin filament-based
203215_s_at    myosin VI                                                             MYO6            2.20   0.25
                                                                                                                   movement
225680_at      hypothetical protein DKFZp434K1815                                    DKFZp434K1815   2.19   0.15   unknown
215143_at      Hypothetical protein FLJ36166                                         FLJ36166        2.18   0.10   unknown
222562_s_at    tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2   TNKS2           2.18   0.22   telomere maintenance / protein amino acid ADP-ribosylation
1552309_a_at   nexilin (F actin binding protein)                                     NEXN            2.15   0.07   unknown
229310_at      kelch repeat and BTB (POZ) domain containing 9                        KBTBD9          2.15   0.13   unknown
1553743_at     similar to hepatocellular carcinoma-associated antigen HCA557b        LOC151194       2.13   0.09   unknown
205149_s_at    chloride channel 4                                                    CLCN4           2.13   0.05   ion transport / chloride transport
205081_at      cysteine-rich protein 1 (intestinal)                                  CRIP1           0.05   0.00   cell proliferation / antimicrobial humoral response (sensu Vertebrata)
                                                                                                                   RNA metabolism / innate immune response / negative regulation of retroviral
204205_at      apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G   APOBEC3G        0.07   0.03
                                                                                                                   genome replication
203824_at      tetraspanin 8                                                         TSPAN8          0.08   0.04   protein amino acid glycosylation
205513_at      transcobalamin I (vitamin B12 binding protein, R binder family)       TCN1            0.08   0.10   ion transport / cobalt ion transport / cobalamin transport
240347_at      Hypothetical protein LOC256021                                             LOC256021   0.11   0.02   unknown
1560684_x_at   MRNA; cDNA DKFZp686P1536 (from clone DKFZp686P1536)                        unknown     0.15   0.02   unknown
204475_at      matrix metalloproteinase 1 (interstitial collagenase)                      MMP1        0.15   0.07   peptidoglycan metabolism / collagen catabolism
200665_s_at
               secreted protein, acidic, cysteine-rich (osteonectin)                      SPARC       0.17   0.11   ossification / transmembrane receptor protein tyrosine kinase signaling pathway
212667_at
233280_at      Nebulette / CDNA FLJ36959 fis, clone BRACE2005898                          NEBL        0.19   0.15   regulation of actin filament length
223423_at      G protein-coupled receptor 160                                             GPR160      0.20   0.20   signal transduction / G-protein coupled receptor protein signaling pathway
                                                                                                                    angiogenesis / protein amino acid phosphorylation / transmembrane receptor
203934_at      kinase insert domain receptor (a type III receptor tyrosine kinase)        KDR         0.20   0.08
                                                                                                                    protein tyrosine kinase signaling pathway / cell differentiation
1565716_at     unknown                                                                    unknown     0.20   0.08   unknown
205959_at      matrix metalloproteinase 13 (collagenase 3)                                MMP13       0.21   0.12   peptidoglycan metabolism / proteolysis and peptidolysis / collagen catabolism
205158_at
               ribonuclease, RNase A family, 4                                            RNASE4      0.21   0.08   mRNA cleavage
213397_x_at
1558937_s_at   Hypothetical LOC389295                                                     LOC153561   0.21   0.09   carbohydrate metabolism
225912_at      tumor protein p53 inducible nuclear protein 1                              TP53INP1    0.22   0.09   apoptosis
                                                                                                                    neurogenesis / perception of sound / cell differentiation / negative regulation of
231798_at      noggin                                                                     NOG         0.22   0.16
                                                                                                                    cell differentiation / cartilage development
242416_at      Ribosomal protein L10a                                                     RPL10A      0.22   0.05   protein biosynthesis
237492_at      unknown                                                                    unknown     0.22   0.13   unknown
205680_at      matrix metalloproteinase 10 (stromelysin 2)                                MMP10       0.23   0.03   collagen catabolism
229053_at      B/K protein                                                                LOC51760    0.23   0.05   transport
203425_s_at
               insulin-like growth factor binding protein 5                               IGFBP5      0.23   0.19   regulation of cell growth / signal transduction
211959_at
                                                                                          APOBEC3G                  RNA metabolism / innate immune response / negative regulation of retroviral
214995_s_at    apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G / 3F               0.23   0.02
                                                                                          APOBEC3F                  genome replication
202310_s_at                                                                                                         skeletal development / phosphate transport / perception of sound / epidermis
               collagen, type I, alpha 1                                                  COL1A1      0.24   0.13
1556499_s_at                                                                                                        development
207149_at      cadherin 12, type 2 (N-cadherin 2)                                         CDH12       0.24   0.05   homophilic cell adhesion / homophilic cell adhesion
235213_at      CDNA clone IMAGE:6201773                                                   unknown     0.24   0.10   unknown
209942_x_at    melanoma antigen family A, 3                                               MAGEA3      0.25   0.01   unknown
210102_at      loss of heterozygosity, 11, chromosomal region 2, gene A                   LOH11CR2A   0.26   0.17   cell cycle / negative regulation of cell cycle
203304_at      putative transmembrane protein                                             BAMBI       0.27   0.13   unknown
211564_s_at    PDZ and LIM domain 4                                                       PDLIM4      0.27   0.02   unknown
1552867_at     zinc finger protein 198                                                    ZNF198      0.27   0.13   unknown
217028_at      chemokine (C-X-C motif) receptor 4                                              CXCR4      0.27   0.13   signal transduction / G-protein coupled receptor protein signaling pathway
222167_at      Poliovirus receptor-related 3                                                   PVRL3      0.27   0.09   unknown
239229_at      Transcribed locus                                                               unknown    0.27   0.06   unknown
1557239_at
               bobby sox homolog (Drosophila)                                                  BBX        0.28   0.13   regulation of transcription, DNA-dependent
1557240_a_at
240052_at
               inositol 1,4,5-triphosphate receptor, type 1                                    ITPR1      0.28   0.14   cation transport / calcium ion transport / signal transduction
231329_at
241031_at      Nuclear localized factor 1                                                      NLF1       0.28   0.13   unknown
1556423_at     KIAA1036                                                                        KIAA1036   0.28   0.07   cell cycle / cell cycle arrest
236256_at      unknown                                                                         unknown    0.29   0.13   unknown
1558048_x_at   unknown                                                                         unknown    0.29   0.10   unknown

209087_x_at
210869_s_at    melanoma cell adhesion molecule                                                 MCAM       0.29   0.09   cell adhesion / morphogenesis
211340_s_at

215314_at
               ankyrin 3, node of Ranvier (ankyrin G)                                          ANK3       0.29   0.11   protein targeting / cytoskeletal anchoring / signal transduction
237839_at
218952_at      proprotein convertase subtilisin/kexin type 1 inhibitor                         PCSK1N     0.29   0.07   extracellular space / endopeptidase inhibitor activity / receptor binding
242055_at      Hypothetical LOC389362                                                          unknown    0.29   0.18   unknown
                                                                                                                        proteolysis and peptidolysis / lipid metabolism / lipid metabolism / endocytosis /
1566903_at     Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor   LRP8       0.29   0.08   endocytosis / signal transduction / cytokine and chemokine mediated signaling
                                                                                                                        pathway
219140_s_at    retinol binding protein 4, plasma                                               RBP4       0.29   0.03   transport / sensory perception / visual perception
215033_at
               transmembrane 4 superfamily member 1                                            TM4SF1     0.30   0.13   unknown
238168_at
238178_at      unknown                                                                         unknown    0.30   0.03   unknown
239893_at      Multiple C2-domains with two transmembrane regions 2                            MCTP2      0.30   0.14   unknown
                                                                                                                        protein amino acid phosphorylation / protein amino acid phosphorylation /
232282_at      protein kinase, lysine deficient 3                                              WNK3       0.30   0.01
                                                                                                                        protein kinase cascade
                                                                                                                        angiogenesis / response to hypoxia / cellular response to starvation / cell
221009_s_at                                                                                                             differentiation / negative regulation of apoptosis / positive regulation of
               angiopoietin-like 4                                                             ANGPTL4    0.30   0.07
223333_s_at                                                                                                             angiogenesis / positive regulation of lipid metabolism / negative regulation of
                                                                                                                        lipoprote
                                                                                                                        protein amino acid phosphorylation / N-linked glycosylation / transmembrane
208212_s_at    anaplastic lymphoma kinase (Ki-1)                                               ALK        0.30   0.06   receptor protein tyrosine kinase signaling pathway / neurogenesis /
                                                                                                                        brain development
241509_at      Pleckstrin homology domain containing, family A member 5                        PLEKHA5    0.30   0.08   unknown
1560662_s_at   hypothetical protein LOC440253                                                    LOC440253   0.30   0.09   unknown
                                                                                                                           lipid metabolism / fatty acid metabolism / prostaglandin metabolism /
242733_at      Hydroxyprostaglandin dehydrogenase 15-(NAD)                                       HPGD        0.31   0.03
                                                                                                                           metabolism
229201_at      Full-length cDNA clone CS0DF014YC15 of Fetal brain of Homo sapiens                unknown     0.31   0.03   unknown
                                                                                                                           angiogenesis / cell fate determination / cell communication / Notch signalling
                                                                                                                           pathway / development / neurogenesis / hemopoiesis / keratinocyte
232406_at      Jagged 1 (Alagille syndrome)                                                      JAG1        0.31   0.07
                                                                                                                           differentiation / regulation of cell migration / regulation of cell proliferation /
                                                                                                                           myoblast
222288_at      Similar to CG9996-PA                                                              unknown     0.31   0.13   unknown
207837_at
               RNA binding protein with multiple splicing                                        RBPMS       0.31   0.14   RNA processing
241897_at
                                                                                                                           activation of MAPK activity / chemotaxis / response to stress / inflammatory
205500_at      complement component 5                                                            C5          0.31   0.09   response / complement activation, alternative pathway / complement activation,
                                                                                                                           classical pathway / G-protein coupled receptor protein signaling pathway
1561166_a_at   Forkhead box P1                                                                   FOXP1       0.31   0.14   transcription / regulation of transcription, DNA-dependent
1562817_at     Protein phosphatase 2, regulatory subunit B (B56), epsilon isoform                PPP2R5E     0.31   0.03   signal transduction
242699_at      unknown                                                                           unknown     0.31   0.19   unknown
               aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase,
209160_at                                                                                        AKR1C3      0.31   0.21   lipid metabolism / prostaglandin metabolism / cell proliferation
               type II)
200632_s_at
               hypothetical protein FLJ20378 [Homo sapiens]                                      NDRG1       0.31   0.10   response to metal ion / cell differentiation
240991_at
229987_at      Ubiquitin specific protease 12                                                    USP12       0.31   0.07   ubiquitin-dependent protein catabolism / ubiquitin cycle
214079_at      dehydrogenase/reductase (SDR family) member 2                                     DHRS2       0.31   0.16   carbohydrate metabolism / metabolism
236435_at      Zinc finger protein 292                                                           ZNF292      0.32   0.10   transcription / regulation of transcription, DNA-dependent
238774_at      Hypothetical protein LOC284058                                                    LOC284058   0.32   0.20   unknown
221489_s_at
               sprouty homolog 4 (Drosophila)                                                    SPRY4       0.32   0.12   development / regulation of signal transduction
1566968_at
1557512_at     Restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)   RSN         0.32   0.12   unknown
205856_at      solute carrier family 14 (urea transporter), member 1 (Kidd blood group)          SLC14A1     0.32   0.14   transport / urea transport
                                                                                                                           nucleosome assembly / transcription / regulation of transcription, DNA-
243479_at      MYST histone acetyltransferase (monocytic leukemia) 4                             MYST4       0.32   0.04   dependent / negative regulation of transcription / chromatin modification /
                                                                                                                           histone acetylation / positive regulation of transcription
                                                                                                                           chemotaxis / cell adhesion / homophilic cell adhesion / neurogenesis / sensory
240558_at      Roundabout, axon guidance receptor, homolog 1 (Drosophila)                        ROBO1       0.33   0.06
                                                                                                                           perception / cell differentiation / positive regulation of axonogenesis
228740_at      Homo sapiens, clone IMAGE:5276765, mRNA                                           unknown     0.33   0.05   unknown
                                                                                                                           transcription / ubiquitin cycle / development / androgen receptor signaling
244633_at      Protein inhibitor of activated STAT, 2                                            PIAS2       0.33   0.16
                                                                                                                           pathway / positive regulation of transcription, DNA-dependent
215018_at      KIAA1731 protein                                                                   KIAA1731    0.33   0.10   unknown
                                                                                                                            regulation of transcription, DNA-dependent / translational initiation / cell
215062_at      Formin-like 2                                                                      FMNL2       0.33   0.05
                                                                                                                            organization and biogenesis / actin / cytoskeleton organization and biogenesis
239793_at      Kinesin 2 60/70kDa                                                                 KNS2        0.33   0.08   unknown
1569091_at     Zinc finger protein 198                                                            ZNF198      0.34   0.10   transcription / regulation of transcription, DNA-dependent
215558_at      Ubiquitin protein ligase E3 component n-recognin 2                                 UBR2        0.34   0.07   protein ubiquitination
1570122_at     PR domain containing 10                                                            PRDM10      0.34   0.09   transcription / regulation of transcription, DNA-dependent / transport
1558710_at     Ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)   ARIH1       0.34   0.11   ubiquitin-dependent protein catabolism / protein ubiquitination
206548_at      transcription factor 7-like 2 (T-cell specific, HMG-box)                           TCF7L2      0.34   0.19   unknown
               myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);
1569652_at                                                                                        MLLT3       0.34   0.14   transcription / regulation of transcription, DNA-dependent
               translocated to, 3
216812_at      unknown                                                                            unknown     0.34   0.05   unknown
1557176_a_at   chromosome 14 open reading frame 37                                                C14orf37    0.34   0.11   unknown
209183_s_at    chromosome 10 open reading frame 10                                                C10orf10    0.34   0.07   unknown
237086_at      unknown                                                                            unknown     0.35   0.02   unknown
207737_at      unknown                                                                            unknown     0.35   0.08   unknown
233112_at      Chromosome 9 open reading frame 150                                                C9orf150    0.35   0.06   unknown
243134_at      LOC440309                                                                          unknown     0.35   0.04   unknown
233034_at      RNA binding motif, single stranded interacting protein 1                           RBMS1       0.35   0.09   DNA replication / DNA replication / RNA processing / regulation of translation
238106_at      Transcribed locus                                                                  unknown     0.35   0.15   unknown
236915_at      unknown                                                                            unknown     0.35   0.05   unknown
226877_at      hypothetical protein LOC132241                                                     LOC132241   0.35   0.03   protein biosynthesis
               protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting
214978_s_at                                                                                       PPFIA4      0.35   0.07   cell communication
               protein (liprin), alpha 4
219410_at      hypothetical protein FLJ10134                                                      FLJ10134    0.35   0.08   unknown
225767_at      hypothetical protein LOC284801                                                     LOC284801   0.35   0.09   unknown
205368_at      KIAA0773 gene product                                                              KIAA0773    0.35   0.14   unknown
1556183_at     Homo sapiens, clone IMAGE:5167446, mRNA                                            unknown     0.36   0.05   unknown
                                                                                                                            receptor mediated endocytosis / chemotaxis / sensory perception / lymphocyte
223454_at      chemokine (C-X-C motif) ligand 16                                                  CXCL16      0.36   0.05
                                                                                                                            chemotaxis
1559331_x_at   CDNA FLJ25030 fis, clone CBL02631                                                  unknown     0.36   0.12   unknown
244677_at      period homolog 1 (Drosophila)                                                      PER1        0.36   0.13   unknown
                                                                                                                            embryonic development (sensu Mammalia) / neurogenesis /
236558_at      Muscleblind-like (Drosophila)                                                      MBNL1       0.36   0.12
                                                                                                                            muscle development / embryonic limb morphogenesis / myoblast differentiation
206214_at      phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)   PLA2G7      0.36   0.06   inflammatory response / lipid catabolism
228906_at      leukemia-associated protein with a CXXC domain            CXXC6       0.36   0.10   unknown
1555310_a_at   p21(CDKN1A)-activated kinase 6                            PAK6        0.36   0.09   protein amino acid phosphorylation
202237_at      nicotinamide N-methyltransferase                          NNMT        0.36   0.03   unknown
235371_at      similar to CG9996-PA                                      LOC389129   0.36   0.10   unknown
1559452_a_at
               ST3 beta-galactoside alpha-2,3-sialyltransferase 1        SIAT4A      0.36   0.10   protein amino acid glycosylation
215874_at
237216_at      GTPase activating Rap/RanGAP domain-like 1                GARNL1      0.36   0.03   unknown
242593_at      KIAA0143 protein                                          KIAA0143    0.36   0.10   unknown
                                                                                                   endocytosis / intracellular signaling cascade / small GTPase mediated signal
233811_at      Ras and Rab interactor 2                                  RIN2        0.37   0.19
                                                                                                   transduction
214078_at      P21 (CDKN1A)-activated kinase 3                           PAK3        0.37   0.05   protein amino acid phosphorylation
232307_at      Thyroid hormone receptor associated protein 2             THRAP2      0.37   0.13   unknown
242726_at      fatty-acid-Coenzyme A ligase, long-chain 3                ACSL3       0.37   0.07   lipid metabolism / fatty acid metabolism / metabolism
236879_at      Hypothetical protein FLJ10808                             FLJ10808    0.37   0.20   ubiquitin cycle
214701_s_at                                                                                        acute-phase response / cell adhesion / transmembrane receptor protein tyrosine
               fibronectin 1                                             FN1         0.37   0.12
235629_at                                                                                          kinase signaling pathway / metabolism / response to wounding / cell migration
215866_at      Coiled-coil-helix-coiled-coil-helix domain containing 3   CHCHD3      0.37   0.09   unknown
241464_s_at    hypothetical FLJ27365 protein                             unknown     0.37   0.08   unknown
                                                                                                   nucleosome assembly / chromatin remodeling / transcription / transcription
                                                                                                   initiation / nucleosome spacing / negative regulation of DNA binding / negative
215786_at      Hepatitis B virus x associated protein                    HBXAP       0.37   0.08
                                                                                                   regulation of transcription, DNA-dependent / positive regulation of viral
                                                                                                   transcription
242759_at      Zinc finger protein 64 homolog (mouse)                    ZFP64       0.37   0.09   transcription / regulation of transcription, DNA-dependent
236816_at      hypothetical protein FLJ13089                             FLJ13089    0.37   0.08   unknown
                                                                                                   protein amino acid phosphorylation / protein amino acid phosphorylation /
234211_at      PTK2 protein tyrosine kinase 2                            PTK2        0.37   0.13
                                                                                                   integrin-mediated signaling pathway
204600_at                                                                                          protein amino acid phosphorylation / signal transduction / transmembrane
               EphB3                                                     EPHB3       0.37   0.07
1438_at                                                                                            receptor protein tyrosine kinase signaling pathway
238032_at      Dehydrogenase/reductase (SDR family) member 3             DHRS3       0.37   0.05   fatty acid metabolism / visual perception / metabolism
244356_at      Protein tyrosine phosphatase, non-receptor type 12        PTPN12      0.37   0.16   protein amino acid dephosphorylation
243067_at      Transcribed locus                                         unknown     0.37   0.02   unknown
241965_at      KIAA0217                                                  KIAA0217    0.37   0.06   unknown
244472_at      unknown                                                   unknown     0.38   0.11   unknown
1562307_at     Ring finger protein 24                                    RNF24       0.38   0.10   protein ubiquitination
                                                                                                                         protein amino acid phosphorylation / regulation of mitosis / development /
242693_at      Cell division cycle 2-like 5 (cholinesterase-related cell division controller)   CDC2L5     0.38   0.09
                                                                                                                         positive regulation of cell proliferation
223217_s_at
               molecule possessing ankyrin repeats induced by lipopolysaccharide (MAIL)         MAIL       0.38   0.05   unknown
223218_s_at
                                                                                                                         neurogenesis / cell recognition / cell proliferation / morphogenesis / heparan
                                                                                                                         sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis /
219049_at      chondroitin beta1,4 N-acetylgalactosaminyltransferase                            ChGn       0.38   0.04
                                                                                                                         UDP-N-acetylgalactosamine metabolism / extracellular matrix organization
                                                                                                                         and biogenesis
1553645_at     hypothetical protein FLJ39502                                                    FLJ39502   0.38   0.13   unknown
1555476_at     iron-responsive element binding protein 2                                        IREB2      0.38   0.05   metabolism / negative regulation of translation
236621_at      ribosomal protein S27 (metallopanstimulin 1)                                     RPS27      0.38   0.16   protein biosynthesis / signal transduction / cell proliferation
223194_s_at    chromosome 6 open reading frame 85                                               C6orf85    0.38   0.09   transport
1552670_a_at   protein phosphatase 1, regulatory (inhibitor) subunit 3B                         PPP1R3B    0.38   0.11   unknown
243598_at      Glycerol-3-phosphate dehydrogenase 2 (mitochondrial)                             GPD2       0.38   0.09   glucose catabolism / glycerol-3-phosphate metabolism / electron transport
232440_at
               Zinc finger, DHHC domain containing 13                                           ZDHHC13    0.38   0.08   positive regulation of I-kappaB kinase/NF-kappaB cascade
237999_at
238610_s_at    Heterogeneous nuclear ribonucleoprotein M                                        HNRPM      0.38   0.08   unknown
237515_at      hypothetical protein FLJ31842                                                    FLJ31842   0.38   0.07   unknown
227501_at      SOCS box-containing WD protein SWiP-1                                            WSB1       0.38   0.13   intracellular signaling cascade
239285_at      Jumonji domain containing 2C                                                     JMJD2C     0.38   0.17   regulation of transcription, DNA-dependent
                                                                                                                         mitotic metaphase / mitotic anaphase / mitotic telophase / cell cycle / mitotic
233921_s_at    MAD1 mitotic arrest deficient-like 1 (yeast)                                     MAD1L1     0.38   0.04
                                                                                                                         checkpoint / cell division
232939_at      Homo sapiens, clone IMAGE:5194204, mRNA                                          unknown    0.38   0.20   unknown
                                                                                                                         immune response / signal transduction / negative regulation of cell proliferation /
237107_at      protein kinase, interferon-inducible double stranded RNA dependent activator     PRKRA      0.38   0.05
                                                                                                                         response to virus
201565_s_at
               inhibitor of DNA binding 2, dominant negative helix-loop-helix protein           ID2        0.38   0.08   development / regulation of transcription / striated muscle contraction
201566_x_at
236636_at      Full-length cDNA clone CS0DF025YH10 of Fetal brain of Homo sapiens               unknown    0.39   0.07   unknown
238067_at      FLJ20298 protein                                                                 FLJ20298   0.39   0.03   unknown
1553349_at     AT rich interactive domain 2 (ARID, RFX-like)                                    ARID2      0.39   0.07   unknown
216144_at      MRNA; cDNA DKFZp434K1126 (from clone DKFZp434K1126)                              unknown    0.39   0.17   unknown
212942_s_at    KIAA1199                                                                         KIAA1199   0.39   0.12   perception of sound
239469_at      Formin binding protein 4                                                         FNBP4      0.39   0.15   cell adhesion / G-protein coupled receptor protein signaling pathway
                                                                                                                         DNA repair / DNA methylation / DNA recombination / regulation of
236778_at      alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.
                                                                                                ATRX       0.39   0.10   transcription, DNA-dependent / chromosome organization and biogenesis
217701_x_at    cerevisiae)
                                                                                                                         (sensu Eukaryota) / perception of sound
219572_at      Ca2+-dependent activator protein for secretion 2                              CADPS2      0.39   0.01   unknown
213413_at      stoned B-like factor                                                          SBLF        0.39   0.07   unknown
226484_at      zinc finger protein 651                                                       ZNF651      0.39   0.06   transcription / regulation of transcription, DNA-dependent
1555938_x_at   vimentin                                                                      VIM         0.39   0.11   structural molecule activity / protein binding / intermediate filament
                                                                                                                       transcription / regulation of transcription, DNA-dependent / transcription from
240307_at      Far upstream element (FUSE) binding protein 1                                 FUBP1       0.40   0.10
                                                                                                                       RNA polymerase II promoter / phosphate transport
1564164_at     hypothetical protein FLJ20054                                                 FLJ20054    0.40   0.14   unknown
1559600_at     Hypothetical protein LOC220686                                                LOC375133   0.40   0.13   unknown
                                                                                                                       carbohydrate metabolism / protein amino acid phosphorylation / striated muscle
208195_at      titin                                                                         TTN         0.40   0.02   contraction / striated muscle contraction / regulation of striated muscle
                                                                                                                       contraction / response to oxidative stress / muscle development
               Transcribed locus, weakly similar to NP_060190.1 signal-transducing adaptor
243584_at                                                                                    unknown     0.40   0.05   unknown
               protein-2; brk kinase substrate
1557504_at     Signal recognition particle 54kDa                                             SRP54       0.40   0.08   protein targeting / SRP-dependent cotranslational protein-membrane targeting
232381_s_at    dynein, axonemal, heavy polypeptide 5                                         DNAH5       0.40   0.05   microtubule-based movement
216770_at      CDNA: FLJ21672 fis, clone COL09025                                            unknown     0.40   0.04   unknown
242239_at      nucleolar protein (NOL1/NOP2/sun) and PUA domains 1                           NOPD1       0.40   0.07   unknown
233369_at      Son of sevenless homolog 2 (Drosophila)                                       SOS2        0.40   0.04   small GTPase mediated signal transduction
213059_at      cAMP responsive element binding protein 3-like 1                              CREB3L1     0.40   0.08   regulation of transcription, DNA-dependent
1556373_a_at   Hypothetical protein MGC35361                                                 MGC35361    0.40   0.05   unknown
                                                                                                                       glucose metabolism / protein amino acid phosphorylation / small GTPase
226452_at      pyruvate dehydrogenase kinase, isoenzyme 1                                    PDK1        0.40   0.06
                                                                                                                       mediated signal transduction
239804_at      Cyclin I                                                                      CCNI        0.40   0.05   regulation of cell cycle / spermatogenesis
1559827_at     hypothetical LOC401074                                                        LOC401074   0.41   0.02   unknown
235094_at      tropomyosin 4                                                                 TPM4        0.41   0.08   muscle development
202478_at      tribbles homolog 2                                                            TRB2        0.41   0.06   protein amino acid phosphorylation
230085_at      Transcribed locus                                                             unknown     0.41   0.06   unknown
1555194_at     CDNA clone IMAGE:3029742, partial cds                                         unknown     0.41   0.06   unknown
203407_at      periplakin                                                                    PPL         0.41   0.08   keratinization
               TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor,
227891_s_at                                                                                  TAF15       0.41   0.12   unknown
               68kDa
226931_at
               ARG99 protein                                                                 ARG99       0.41   0.11   unknown
244506_at
242646_at      CGI-85 protein                                                                CGI-85      0.41   0.14   unknown
                                                                                                                       transcription / regulation of transcription, DNA-dependent / regulation of
215620_at      ras responsive element binding protein 1                                      RREB1       0.41   0.06
                                                                                                                       transcription, DNA-dependent / transcription from RNA polymerase II promoter
                                                                                                                    / Ras protein signal transduction / development
233706_at     Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2   NFATC2      0.42   0.07   regulation of transcription, DNA-dependent
                                                                                                                    intracellular protein transport / signal transduction / small GTPase mediated
221830_at     RAP2A, member of RAS oncogene family                                        RAP2A       0.42   0.03
                                                                                                                    signal transduction

202769_at
202770_s_at
              cyclin G2                                                                   CCNG2       0.42   0.09   regulation of cell cycle / cell cycle checkpoint / mitosis / cell division
211559_s_at
228081_at

1553459_at    hypothetical protein FLJ39660                                               FLJ39660    0.42   0.04   unknown
203227_s_at   sarcoma amplified sequence                                                  SAS         0.42   0.04   positive regulation of cell proliferation
                                                                                                                    protein amino acid phosphorylation / apoptosis / induction of apoptosis / protein
243797_at     serine/threonine kinase 17b (apoptosis-inducing)                            STK17B      0.42   0.03
                                                                                                                    kinase cascade
1558766_at    CDNA clone IMAGE:4332981, partial cds                                       unknown     0.42   0.10   unknown
232290_at     G protein-coupled receptor, family C, group 5, member A                     GPCR5A      0.42   0.07   signal transduction / G-protein coupled receptor protein signaling pathway
216472_at     Intersectin 1 (SH3 domain protein)                                          ITSN1       0.42   0.02   synaptic vesicle endocytosis
220306_at     family with sequence similarity 46, member C                                FAM46C      0.43   0.04   unknown
238363_at     Catalase                                                                    CAT         0.43   0.04   electron transport / response to oxidative stress / hydrogen peroxide catabolism
233202_at     similar to KIAA1714 protein                                                 LOC389725   0.43   0.06   unknown
234501_x_at   Putative homeodomain transcription factor 1                                 PHTF1       0.43   0.06   transcription / regulation of transcription, DNA-dependent
243996_at     Transcribed locus                                                           unknown     0.43   0.01   unknown
239830_at     unknown                                                                     unknown     0.43   0.02   unknown
212776_s_at   KIAA0657 protein                                                            KIAA0657    0.43   0.05   unknown
239619_at     Zinc finger protein 395                                                     ZNF395      0.44   0.05   unknown
232705_at     Leucine rich repeat (in FLII) interacting protein 2                         LRRFIP2     0.44   0.03   unknown
243350_at     Chromosome 5 open reading frame 15                                          C5orf15     0.44   0.03   unknown
1566001_at    Ankyrin repeat domain 11                                                    ANKRD11     0.44   0.03   unknown
                                                                                                                    fructose 2,6-bisphosphate metabolism / fructose 2,6-bisphosphate metabolism /
228499_at     6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4                       PFKFB4      0.44   0.05
                                                                                                                    metabolism
              UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-
216757_at                                                                                 GALNT7      0.45   0.02   carbohydrate metabolism / O-linked glycosylation
              acetylgalactosaminyltransferase 7 (GalNAc-T7)
228723_at     Stromal cell derived factor receptor 1                                      SDFR1       0.45   0.04   unknown
1558903_at    chromosome 22 open reading frame 1                                          C22orf1     0.45   0.03   unknown
229683_s_at   Potassium channel tetramerisation domain containing 15                      KCTD15      0.46   0.02   potassium ion transport
232599_at     SEC15-like 1 (S. cerevisiae)                                                SEC15L1     0.46   0.03   vesicle docking during exocytosis / protein transport
1563595_at         SLIT-ROBO Rho GTPase activating protein 3                                                      SRGAP3                 0.46        0.03     unknown
242308_at          mucolipin 3                                                                                    MCOLN3                 0.46        0.00     cation transport
1563010_at         Integrin, beta 8                                                                               ITGB8                  0.46        0.02     cell-matrix adhesion / integrin-mediated signaling pathway
242428_at          RP42 homolog                                                                                   RP42                   0.46        0.01     unknown
213285_at          transmembrane protein 30B                                                                      TMEM30B                0.46        0.03     unknown
239725_at          GPI deacylase                                                                                  PGAP1                  0.46        0.02     unknown
201313_at          enolase 2, (gamma, neuronal)                                                                   ENO2                   0.46        0.01     glycolysis
1560758_at         unknown                                                                                        unknown                0.46        0.02     unknown
238199_x_at        similar to OK/SW-CL.16                                                                         LOC440552              0.47        0.02     unknown
1559597_at         unknown                                                                                        unknown                0.48        0.01     unknown
221208_s_at        hypothetical protein FLJ23342                                                                  FLJ23342               0.49        0.02     unknown
212098_at          hypothetical protein LOC151162                                                                 LOC151162              0.49        0.00     unknown


‡
  Fold change of a gene derived from at least 3 of 4 PC-3/ST7-1a clones, which have 2 fold expression changes compared to the pool of PC-3/pcDNA3.1 control for all the listed probe sets.
†
 Standard deviation calculated from the average values of at least 3 of 4 PC-3/ST7-1a clones for all the probe sets listed.
§
   GO biological process of identified genes summarized by the results of Gene Ontology Categories that were allocated using data retrieved from Affymetrix Database and literature search.

				
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posted:6/12/2012
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