QuickTime™ and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
Subject : Chemistry 51
Name : JJ
Prof. : Dr. Paul Shin
These days, we can’t live without chemical
synthetic substance. Many problems occur such as
abnormalities in male reproductive organs and
female reproductive diseases by chemical synthetic
substance. These substances combined with
hormone receptor (ER; estrogen receptor) then
disrupt endocrine; that’s why we call these
chemicals endocrine disruptors. They also
accumulate in body long time so, it’s influence on
descendant. However, we can reduce and prevent
the problems. We have to find a solution.
I use a plastic container with a microwave
frequently. I heard that it is very unhealthy acting
because environmental hormones, endocrine
disruptors. What is an endocrine disruptor, how it
work and then, how can I prevent from injury by
What is hormone?
A hormone is a Chemical messenger that carries a signal
from one cell to another via the blood.
All *multicellular organisms produce hormones.
Those released in one part of the body send signals for
profound physiological changes in other parts of the body.
Q uic kT ime ™ a n d a
T IFF (U n co mp r e ss ed ) de c om p re s so r
a re n ee d ed to s ee this p i tu re .
Multicellular organism : Organisms consisting of more than one cell.
Function of Hormone
Hormones circulate in the bloodstream and
control the actions of certain cells or organs.
Stimulation or inhibition of growth.
Activation or inhibition of the immune system.
Control the reproductive cycle of virtually all
Control sexual functions.
Decide of sex also distinction between male and
female of brain.
Environmental Hormones (EDCs :
Endocrine disrupting chemicals) are
chemicals substance by human action of
industry, not from organisms. It works like
naturally produced hormones but they
disrupt endocrine of human and other
The EDCs combines with hormone receptor
of cell. They interfere with the transport of a
hormone or its elimination from the body.
EDCs are more affected than the other
toxicity chemicals. They concentrate in a
body and transferable by food chain to the
others so, its more dangerous. - *biological
concentration, biological magnification.
Biological concentration, magnification : A cumulative increase in the
concentrations of a persistent substance in successively higher levels of the food
Type of Endocrine disruptors
DDT (Dichlorodiphenyltrichloroethane) :
one of the sources of these pollutants is
pesticide use. Americans use some 2 billion
pounds of pesticides each year, and some
pesticide residues stay in the food chain for
decades. It responsible for congenital
malformations in wild animals, the decline
of sperm counts in men, and breast cancer
Dioxins : This Chemical compounds are
also environmental pollutants. Dioxins
occurs when heating our food in the
microwave using plastic containers. High
heat and plastics releases dioxins into the
food and ultimately into the cells of the
body. Dioxins are carcinogens and highly
toxic to the cells of our bodies.
PCB (Polychlorinated biphenyl) : PCBs
were used as coolants and fluids for
transformers and capacitors, stabilizing
additives in flexible PVC coatings of
electrical wiring. Higher chlorinated PCBs
are associated with the neurological
damage. Common symptoms included
dermal and ocular lesions, irregular
menstrual cycles and a lowered immune
The others :
- DES (Diethylstilbestrol) : synthetic estrogen,
is a drug to prevent miscarriages. It was found
to be a teratogen when given to pregnant
- BPA (Bisphenol A) : Plastic water and baby
bottles, food and beverage can linings and
dental sealants ate the most commonly
encountered uses of this chemical. This
chemicals effects lead to health problems such
as , in men, lowered sperm count and infertile
sperm and produce precursors of breast cancer.
Bisphenol A are
QuickTime™ an d a these Endocrine
TIFF (Uncompressed) decompressor
are need ed to see this p icture. disrupters’
are very similar to
Damage caused by
- Masculinization of females.
- Feminization of males.
- brain and neurological problems.
- abnormal and malformed reproductive
- reductions in male fertility.
(lower sperm volume, numbers and motility)
- Increase cancers in relation to hormone.
(female reproductive diseases)
- Sex ratio. (fewer women)
- Impaired behavior/mental, immune and
thyroid function in developing children.
- earlier puberty.
- abnormalities in male reproductive organs.
Buy organic food, avoid eating instant food.
Avoid using pesticides in your home or yard, or on
Avoid heating food in plastic containers, or storing
fatty foods in plastic containers or plastic wrap.
Do not give young children soft plastic toys, since
these leach potential endocrine disrupting
Support efforts to get strong government
regulation of and increased research on endocrine
Endocrine disruptor is one of a problems by
civilization. Most problems by civilization
originated in artificial synthetic chemicals. More
important thing is, they doesn’t come out at
once so, it’s difficult to protect. For example,
DES was a medicine to prevent abortion for
pregnant woman but this medicine may made a
deformed child. We must be careful when we
using the synthetic chemicals.
McCully, s. international journal of food science & technology, 2002.