Docstoc

交大生科院2007年生物科技學術研討會_Journal_ 中文姓名 賴彥龍 英文

Document Sample
交大生科院2007年生物科技學術研討會_Journal_ 中文姓名 賴彥龍 英文 Powered By Docstoc
					           交大生科院 2007 年生物科技學術研討會(Journal)

 中文姓名               賴彥龍                英文姓名                  Yan-Long Lai

 學    號            9651804               Email       laiyanlong.bi94g@nctu.edu.tw

 系    級           生資博一                 指導教授                      黃鎮剛


 論文題目      pKNOT: the protein KNOT web server


作者中、英
文姓名(第一 Yan-Long Lai(賴彥龍)1, Shih-Chung Yen(顏士中)1, Sung-Huan Yu(于
作者用粗體 松桓)1 and Jenn-Kang Hwang(黃鎮剛)
  字)
           □   生 化 分 生 與 生 物 醫 學 (Biochemistry, Molecular Biology and
             Biomedicine)
 論文領域      □ 生物工程相關領域 (Bioengineering) (生物物理、生物電子及奈米
             生物等)
            系統生物與生物資訊 (System Biology and Bioinformatics)
                                                      Impact
                                                                  6.317
                                                      Factor
 期刊名稱      Nucleic Acids Research
                                                     學術排名
                                                                  36/262=13.7%
                                                     (百分比)
 發表時間      July 2007

           Knotted proteins are more commonly observed in recent years due to the
           enormously growing number of structures in the Protein Data Bank
           (PDB). Studies show that the knot regions contribute to both ligand
           binding and enzyme activity in proteins such as the chromophore-binding
           domain of phytochrome, ketol–acid reductoisomerase or SpoU
           methyltransferase. However, there are still many misidentified knots
           published in the literature due to the absence of a convenient web tool
 論文摘要
           available to the general biologists. Here, we present the first web server
(不超過 300
           to detect the knots in proteins as well as provide information on knotted
 字為原則)
           proteins in PDB—the protein KNOT (pKNOT) web server. In pKNOT,
           users can either input PDB ID or upload protein coordinates in the PDB
           format. The pKNOT web server will detect the knots in the protein using
           the Taylor's smoothing algorithm. All the detected knots can be visually
           inspected using a Java-based 3D graphics viewer. We believe that the
           pKNOT web server will be useful to both biologists in general and
           structural biologists in particular.
      Protein Knot、Methyltransferase、Cinquefoil knot、Trifoil Knot。
關鍵字

				
DOCUMENT INFO
Shared By:
Categories:
Tags:
Stats:
views:13
posted:6/10/2012
language:
pages:2