Diabetes Insipidus Introduction Diabetes Insipidus is a rare disease which results from disruption of the system of the body that regulates water re-absorption in kidneys. This defect in the water regulation system of the body leads to most common symptoms of Diabetes Insipidus. A very good resource to get detailed information about Diabetes Insipidus is Diabetes Insipidus website. www.diabetes-insipidus.info is full of information about causes, symptoms, treatment options and prognosis of this disease. Most Common Symptoms of Diabetes Insipidus Some of the most presented symptoms of are: Severe thirst that does not get satisfied Frequent urination Large amounts of urine passing which may sometimes be around 20 liters per day What Are the Causes of Diabetes Insipidus The primary cause of diabetes insipidus is related to ADH ( Anti diuretic Hormone) which is also known as Vasopressin. ADH is critical in regulating the amount of liquid in human body. Hypothalamus, a part of the brain, produces ADH which is then stored in pituitary gland which releases it into blood stream in case of need. When the amount of water in the body decreases, Pituitary glands release ADH hormone to instruct kidneys to decrease outflow of water in the form of urine. In a patient suffering from Diabetes Insipidus, ADH is not produced in sufficient quantity and kidneys pass on large amounts of water in the form of urine. Main Types of Diabetes Insipidus There are mainly two types : Cranial diabetes insipidus Cranial Diabetes Insipidus, also known as Central Diabetes Insipidus is caused by less production of ADH in the body leading to excessive production of urine. This type is the most common and can result from damage to Pituitary Gland or hypothalamus resulting from any of the following reasons: Head Injury Infection Operation or surgery Brain Tumor However, in one out of every three cases of Cranial Diabetes Insipidus, the cause of the disease is unknown. Nephrogenic diabetes insipidus In case of Nephrogenic Diabetes Insipidus, the body produces enough amount of ADH, however, kidneys fail to respond to ADH due to problems with the kidneys or damage to the kidneys. Nephrogenic Diabetes Insipidus can also result as side effects of some medications like lithium ( which has been used extensively in mental health diseases ). In some very rare cases, Nephrogenic Diabetes Insipidus is attributed to hereditary genes. Treatments for Diabetes Insipidus No specific medical treatment is required in cases of mild forms of Cranaial Diabetes Insipidus and the patient may continue to live normal life by drinking more water to compensate for the loss of water in urine. In severe cases of Cranial or Central Diabetes Insipidus, a drug named Desmopressin is prescribed by the physicians to compensate the shortage of ADH. The treatment of Nephrogenic Diabetes Insipidus is done by using drugs named thiazide diuretic which reduce the amount of urine being produced by the kidneys. If you want to know more about Diabetes Insipidus then visit this very good resrouce for diabetes insipidus related information. All medicines should be used only on the prescription of your physician to avoid complications.