Malignant Mesothelioma Malignant Mesothelioma is uncontrolled cellular growth. In normal condition in the human body, cells in the hair, blood, bones and other organs follow a predetermined life cycle. They grow to a predetermined point and then die off. These cells are then replaced by new, healthy cells. In the case of cancers such as Mesothelioma, cells are damaged to some degree, and as the body reproduces them they begin to out-compete healthy cells, leading to system failures. Malignant Mesothelioma cells are comprised of three primary types: Epithelioid Cells, Sarcomatoid Cells, or a combination of types known as Biphasic. The tragedy of Malignant Mesothelioma is that it takes many years before most symptoms become apparent and a diagnosis is made. In most cases, by the time the Malignant Mesothelioma is discovered in the victim, it is in the later stages of the disease and much more difficult to treat. Epithelioid Mesothelioma Cells The most common and treatable form of Mesothelioma cells are Epithelioid Cells. When looked at on a microscopic level, these cells are seen as “papillary” or tubular growth. Epithelioid Cells generally affect membranes and tissues covering organs. Between 50-70% of Malignant Mesothelioma diagnosis fall into the category of Epithelioid Cells providing patients with the highest likelihood of responding to treatment. Sarcomatoid Mesothelioma Cells When Malignant Mesothelioma consists of Sarcomatoid cells, it is considered the most serious of the three cell types. Sarcomatoid cells rarely respond to current treatments. Sarcomatoid cells are the rarest manifestation of Malignant Mesothelioma. Sarcomatoid cells occur in roughly 10-20% of patients diagnosed with Mesothelioma. These cells appear as spindle-shaped patterns or groups of cells that overlap one another. Sarcomatoid cells generally originate in the support tissues such as bone, cartilage, muscle, and fats. The prognosis for Sarcomatoid Mesothelioma patients is generally grim, with death usually occuring within six months of diagnosis Mesothelioma. Biphasic Mesothelioma Biphasic Mesothelioma is a combination of the other two Malignant Mesothelioma cell types. This form of Mesothelioma may include both the positive and negative aspects of Sarcomatoid and Epithelioid Cells. About 20-35% of all Malignant Mesothelioma cases are mixed or Biphasic.