Hypopharyngeal Cancer – Pipeline Review, H1 2012

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					     Hypopharyngeal Cancer – Pipeline Review, H1 2012


                                                                                          Reference Code: GMDHC1930IDB
                                                                                              Publication Date: April 2012




Hypopharyngeal Cancer – Pipeline Review, H1 2012                                              GMDHC1930IDB / Pub April 2012
© Global Markets Direct. This report is a licensed product and is not to be photocopied                             Page(1)
Hypopharyngeal Cancer – Pipeline Review, H1 2012




Table of Contents
Table of Contents ............................................................................................................................................................................... 2
    List of Tables ................................................................................................................................................................................. 5
    List of Figures ................................................................................................................................................................................ 5
Introduction......................................................................................................................................................................................... 6
    Global Markets Direct Report Coverage ........................................................................................................................................ 6
Hypopharyngeal Cancer Overview ..................................................................................................................................................... 7
Therapeutics Development................................................................................................................................................................. 8
    An Overview of Pipeline Products for Hypopharyngeal Cancer ..................................................................................................... 8
Hypopharyngeal Cancer Therapeutics under Investigation by Universities/Institutes ...................................................................... 10
Late Stage Products ......................................................................................................................................................................... 12
    Comparative Analysis .................................................................................................................................................................. 12
Mid Clinical Stage Products.............................................................................................................................................................. 13
    Comparative Analysis .................................................................................................................................................................. 13
Early Clinical Stage Products ........................................................................................................................................................... 14
    Comparative Analysis .................................................................................................................................................................. 14
Hypopharyngeal Cancer Therapeutics – Products under Investigation by Universities/Institutes .................................................... 15
    Assessment by Combination Products ........................................................................................................................................ 16
    Assessment by Route of Administration ...................................................................................................................................... 17
    Assessment by Molecule Type .................................................................................................................................................... 19
Drug Profiles..................................................................................................................................................................................... 21
    Cisplatin + Fluorouracil + Radiation Therapy - Drug Profile ......................................................................................................... 21
         Product Description................................................................................................................................................................. 21
         Mechanism of Action ............................................................................................................................................................... 21
         R&D Progress ......................................................................................................................................................................... 21
    Radiation Therapy + Cetuximab - Drug Profile ............................................................................................................................ 23
         Product Description................................................................................................................................................................. 23
         Mechanism of Action ............................................................................................................................................................... 23
         R&D Progress ......................................................................................................................................................................... 23
    Cisplatin + Erlotinib Hydrochloride + Radiation Therapy - Drug Profile ....................................................................................... 25
         Product Description................................................................................................................................................................. 25
         Mechanism of Action ............................................................................................................................................................... 25
         R&D Progress ......................................................................................................................................................................... 25
    Carboplatin + Cisplatin + Docetaxel + Fluorouracil + Lapatinib + Radiation Therapy - Drug Profile ............................................ 27
         Product Description................................................................................................................................................................. 27
         Mechanism of Action ............................................................................................................................................................... 27
         R&D Progress ......................................................................................................................................................................... 28
    Cisplatin + 5-Fluorouracil + Radiation Therapy - Drug Profile ..................................................................................................... 30
         Product Description................................................................................................................................................................. 30
         Mechanism of Action ............................................................................................................................................................... 30
         R&D Progress ......................................................................................................................................................................... 30
    Cetuximab + Cisplatin + Radiation Therapy - Drug Profile .......................................................................................................... 32
         Product Description................................................................................................................................................................. 32



Hypopharyngeal Cancer – Pipeline Review, H1 2012                                                                                                   GMDHC1930IDB / Pub April 2012
© Global Markets Direct. This report is a licensed product and is not to be photocopied                                                                                                   Page(2)
Hypopharyngeal Cancer – Pipeline Review, H1 2012



        Mechanism of Action ............................................................................................................................................................... 32
        R&D Progress ......................................................................................................................................................................... 33
    TS-1 + Nedaplatin + Radiation Therapy - Drug Profile ................................................................................................................ 34
        Product Description................................................................................................................................................................. 34
        Mechanism of Action ............................................................................................................................................................... 34
        R&D Progress ......................................................................................................................................................................... 34
    S-1 + Radiation Therapy - Drug Profile........................................................................................................................................ 35
        Product Description................................................................................................................................................................. 35
        Mechanism of Action ............................................................................................................................................................... 35
        R&D Progress ......................................................................................................................................................................... 35
    Docetaxel + Radiation Therapy - Drug Profile ............................................................................................................................. 36
        Product Description................................................................................................................................................................. 36
        Mechanism of Action ............................................................................................................................................................... 36
        R&D Progress ......................................................................................................................................................................... 36
    S-1 + Radiation Therapy - Drug Profile........................................................................................................................................ 38
        Product Description................................................................................................................................................................. 38
        Mechanism of Action ............................................................................................................................................................... 38
        R&D Progress ......................................................................................................................................................................... 38
    Docetaxel + Radiation Therapy - Drug Profile ............................................................................................................................. 40
        Product Description................................................................................................................................................................. 40
        Mechanism of Action ............................................................................................................................................................... 40
        R&D Progress ......................................................................................................................................................................... 40
    Panitumumab + Cisplatin + Fluorouracil + Radiation Therapy - Drug Profile............................................................................... 41
        Product Description................................................................................................................................................................. 41
        Mechanism of Action ............................................................................................................................................................... 41
        R&D Progress ......................................................................................................................................................................... 41
    Erlotinib Hydrochloride + Radiation Therapy - Drug Profile ......................................................................................................... 43
        Product Description................................................................................................................................................................. 43
        Mechanism of Action ............................................................................................................................................................... 43
        R&D Progress ......................................................................................................................................................................... 43
    Cisplatin + Paclitaxel + Radiation Therapy - Drug Profile ............................................................................................................ 45
        Product Description................................................................................................................................................................. 45
        Mechanism of Action ............................................................................................................................................................... 45
        R&D Progress ......................................................................................................................................................................... 45
    
				
DOCUMENT INFO
Description: Hypopharyngeal Cancer - Pipeline Review, H1 2012', provides an overview of the Hypopharyngeal Cancer therapeutic pipeline. This report provides information on the therapeutic development for Hypopharyngeal Cancer, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Hypopharyngeal Cancer. 'Hypopharyngeal Cancer - Pipeline Review, H1 2012' is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.
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