BIOL 121 – The Unity of Life.ppt by liningnvp


									BIOL 121 – The Unity of Life

       Instructor: DW Buckalew
        Office: 305A Sciences
 Office Hours: M 3:00 – 5:00 pm
                F 8:00-10:00 am
Welcome aboard!

                  The Biosphere is the limit!!
How to Succeed in Science courses
•Attendance is a MUST – you will need to take notes!
•Timeliness is a MUST – you need to be present to take notes!
•Read the textbook from this day forward….
•Begin projects early
•Don’t be rude – turn off cell phones, refrain from talking
•Biology I is essentially Intro Biochemistry – look at the topics!
   •You’ve seen/heard much of the info before? Probably so.
   •You’ve had to synthesize the amount req’d for Biology I?
                                            Probably not.
How to Succeed in Science courses
COMMUNICATE – talk with faculty when problems arise
                  (notice the word “IF” was not used)
“ROLL WITH THE PUNCHES” – bounce back from low
                               test/quiz scores
                          the degree is difficult
KEEP YOUR EYES ON THE PRIZE – graduation is closer
                                than you think!
                    Work Hard!!
1) Brett Montgomery ('03) MD program at EVMS
2) Matthew Kren ('04) MS Biology – VCU; DVM Program – Ross University
3) Renae Trombley ('04) Doctoral program - VCU/MCV Physical Therapy
4) Richard Scherer ('04) Doctoral program - VCU/MCV Physical Therapy
5) Brian Belliveau ('05) Ph.D. program in Molecular Biology at Notre Dame
6) Nick Hopson ('05) Doctoral program - VCU/MCV Physical Therapy
7) Amber Weems ('05) VCU School of Dentistry
8) Ryan Dunn ('05) MD program in Pathology at Duke University
9) Paul Hetterich ('05) MS in Clinical Micro/Immuno at VCU/MCV
10) Stephen "Matt" Akers ('04) MD/PhD program at West Virginia University
11) Frankie Simmons ('03) MD program - Howard University
12) Stephanie Thomas ('04) Ph.D. Program at Old Dominion University
14) Stuart Bertsch ('05) MD program – VCU/MCV
15) Sara Lee ('05) MS program – Forensics - Marshall University
16) Katie Wells ('05) Doctoral program - Shenandoah University Physical Therapy
17) Laura Wooldridge ('05) Physician's Assistant program - Shenandoah University
18) Casey Dertzbaugh ('06) Doctoral program VCU/MCV Physical Therapy
19) Adrienne Hampton ('05) MD program - Northwestern University
20) Kelley Jernigan (06) Nursing Program at VCU
21) Quintin Lewis (06) Ph. D. Program in Molecular Biology – VCU
22) Jerry McCoy ('05) Teaching at Emporia Private High School
23) David Walker ('06) NOVA University School of Dentistry
24) Carolyn Howard ('06) MS program in Occupational Therapy - JMU
25) Crystal Freels ('06) Science teacher – Roanoke school district
26) Ray Stephens ('06) VCU Dental School
27) Albert Tuono ('06) DOM program - WV School of Osteopathic Medicine
28) Colleen Schamber ('06) MS in Biomedical Engineering – UVA
29) Nicole Woznick ('06) PharmD program - VCU
30) Kelly Brake ('06) - VCU School of Nursing
31) Catherine Dunn ('05) - Molecular lab tech at Cornell Medical College
32) Chelsea Norton ('05) - Lab specialist - Wyeth Pharmaceuticals
33) Catherine Melvin ('05) - Ph.D program in Microbiology - GMU
34) Christina Stewart ('06) - Lab technician - VCLS Richmond, VA
35) Michelle Wagner ('05) - VCU School of Nursing
36) Ashley Martin ('04) - MS program in Clinical Lab Sciences - VCU/MCV
37) Jason Chambers (06) – MS in Marine Biology – UNC-Wilmington
38) Tiffany Crane (07) – Post-Bacc – University of Cincinnati
39) Jennifer Smith Doss (07) – Officer, Va DCR – Fish and Wildlife
40) Michael Edwards (07) – DVM program – VA Tech
41) Jason Ferguson (07) – MS program in Fisheries – Univ Tennessee
42) Oscar Gonzalez (07) – Biomedical Engineering – VCU
43) Jane Ashley Hawkins (07) – BS Nursing program – Univ of South Carolina
44) Michael Joyce (07) – Post- Bacc – Pre-medical program – VCU
45) Courtney Kreft (07) – 2nd Lt – MASH surgical unit – Afghanistan
46) Joel Rowe (07) – MD program – VCU/MCV
47) Amanda Simmons (07) – MS in Microbiology – ODU
48) Whitney Slack (07) – MS Program in Nursing VCU/MCV
49) Emily Sturgill (07) – BS Nursing Program – GMU
50) Natalie Haines (07) – QC Biologist – American Type Culture Collection
51) Matt Lusk (06) – UNC Coastal Studies Institute
Your name here (‘11) – attending graduate school at….
                     - attending professional school at…
                     - teaching science at……
                     -lab/field scientist at/for….

              Your future begins today!!
Hot Topics in
            Emerging/Re-emerging diseases
                 Hot Topics in
Global Warming
Hot Topics in Biology:   Decline in Biodiversity
Hot Topics in Biology:
                         Fetal Stem Cells
Career options – what’s out there

• Professional scientists              • Science-trained
   – often immersed in research and      professionals
                                          – Often employed by industry,
       academia                             business, education, and
       government                           government in different ways
       industry                           – Usually requires a M.S. or
   – Often requires a Ph.D. or other        equivalent degree
     advanced degree degree
   You can enter many science
                                            Biology B.S. with additional study:
       careers with a B.S.
                                            •Science journalism
•Research technician
                                            •Medical technology
•Lab coordinator
                                            •1° and 2° education
•Regulatory agent
                                            •Pharmaceutical/agrichemical sales
•Quality control specialist
                                            •Bioinformatics including law
•Life science product sales
                                            •Museum curator

               Biology B.S. combined with other degree (i.e., MBA, JD)
               •High tech business or hospital management
               •Financial analyst of biotechnology firms
               •Patent law/technology transfer/environmental law
               •Environmental engineering
Biology Ph.D. :
                                                •Average of 4 years beyond PLUS 4+ years
•Average of 5-7 years beyond B.S.               of residency/specialized training
•College/university teacher
•Research director in academia,                 •Other professional medical degrees…
government, and industry                                  P.A.
                  Typically obtained via paid             D.P.T.

The number of Biology Ph.D.’s employed in business
and industry has increased steadily…over 50% of new
Ph.D.’s are employed outside academia (Tobias, 2005)

                                Over 1/3 have moved into management roles
  So let’s get started in the quest….
                 Chapter 1- The Science of Biology

• Biology is “the study of life”
  I. Characteristics of life:
   –   Cellular organization
   –   Order
   –   Sensitivity
   –   Growth, development, and reproduction
   –   Energy utilization
   –   Evolutionary adaptation
   –   Homeostasis
II. The Hierarchical organization of life

• At the cellular level…
   Atoms join to form
   Molecules join to form
     larger molecules (e.g.
   Large molecules are
     assembled to form
   Organelles are contained
     within a larger
     organized cell
II. The Hierarchical organization of life

• At the organismal level…
   Cells organized in 3 levels:
        organ system

   The set of organ systems form
   the intact organism
 II. The Hierarchical organization of life
• At the population level…
   Individual organisms form
   All populations of a single
     type of organism constitute
     the species
   All populations of different
     organisms living together in
     one place make a
   The biological community
     PLUS the abiotic factors
     make up an ecosystem
       III. The Process of Science
                      (science = L. “to know”)

Charles Darwin (1809-1882) sought natural rather than supernatural
  causes for the unity/diversity of nature and, in doing so, revolutionized
  biology. Published the then controversial book, On the Origin of
  Species…etc in 1859.
         The Process of Science
• Science seeks answers
  to natural phenomena
  – Activities that can be
    observed and measured
  – Activities that can be
    verified through testing
        The Process of Science
• Science uses 2 ways to
  approach problem
   – Inductive reasoning =
      Generalization that
        summarizes many

   – Deductive reasoning =
      Hypothesis testing and
       “if-then logic” –
       reasoning flows from
       general to specific
How Science Is Done
Science is a systematic process of testing alternative hypotheses
        Unifying Themes of Science
• Cell theory
  – Robert Hooke (1665) to Anton van Leeuwenhoek (1700) to
    Schleiden and Schwann (1839)
  – All living organisms are made of cells, and all living cells come
    from other living cells.
  – Later, it was proposed that all cell came from pre-existing cells.
• Molecular theory – “central dogma of
  molecular biology”
  – DNA is the molecule of inheritance
  – DNA encodes genes which make-up and control living
  – DNA  RNA  Protein
     Unifying Themes of Science
• Evolutionary change
  – Life-forms have evolved varying characteristics to
    adapt to varied environments.

• Evolutionary conservation
  – Some characteristics of earlier organisms are preserved
    and passed on to future generations.
               Articles on reserve
              for 1st Article Review
• Nestle, M. 2007. Eating made simple. Scientific
  American. 297: 60-69. (Sept)

• Grossman, D. 2004. Spring forward. Scientific
  American. 290: 84-92. (Jan)

• Rennie, J. 2002. 15 Answers to creationist
  nonsense. Scientific American. 287: 78-85.(July)

    LWU electronic reserve:

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