Elementary Bioorganic Chemistry

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					                                   Elementary Bioorganic Chemistry
                                       Chem 1120 Spring 2008
                                     Lecture MWF 9:40-10:30AM in HEB 2008

Instructor: Dr. Alison Livingston
Email: alison@chem.utah.edu
Phone: 581-3985
Office Hour: Friday 8:30-9:30AM in HEB 1156 or by appointment
Text: Fundamentals of General, Organic, and Biological Chemistry 5th ed. by McMurry, Castellion, and

The purpose of this course is to provide the basics of organic and biological chemistry to students who wish to pursue a
career in the field of medical science. This course consists of lecture, discussion and laboratory components. Attendance
at lecture and discussion periods is not required, but will greatly enhance your understanding of the material and is highly
recommended. Attendance at laboratory periods is mandatory, and roll will be taken.

We will be following the topics of the text in chapters 13-28. Due to the large quantity of material discussed throughout
the semester, I will be emphasizing certain topics, while some will not be discussed at all. The text will be a valuable
resource in your study, but the exams will be based on material discussed in lecture. Therefore, it is in your best interest
to attend lecture periods.

There will be 4 exams given during class periods throughout the semester and each will be worth 100 points. You will be
allowed to drop 1 out of the 4 exams given. There will not be any make-up exams given in this course. If you have a
conflict with a particular exam date, that missed exam will count as your dropped exam. There will be a 2 hour final
exam worth 200 points. No part of the final exam can be dropped. The final exam will be during final exam week and
will be given in the same room as the lecture (Wed, April 30th from 8-10AM in HEB 2008). Please note that the final
exam is cumulative! Any concerns with grading of the exams must be submitted to ME (Dr. Livingston) in writing within
a week of the return of the exam. Any exam regrades are subject to complete re-evaluation on ALL questions. Regrades
cannot be submitted to the TAs, although it is a good idea to consult with your TA about your concern prior to exam

You will only be allowed to use a basic function or scientific calculator on exams. No graphing calculators, cell phones,
or PDAs allowed (anything that is capable of saving data).

Laboratory and Discussion
Attendance at laboratory periods is required at 10 out of 11 labs. Labs and discussions will begin the week of January
14th. Everyone MUST attend their laboratory section during the first week of class in order to secure your place in that
section. During the first week, you will be given a lab safety quiz that is mandatory as one of your 10 required labs. Each
lab will be worth 10 points for a total of 100 possible points for the lab portion. Your TAs will further discuss the
requirements for lab during the first lab period.

The course will be graded on a curve, with the average total score being in the C+ range. The total possible points for the
course are as follows (for example, for a student who dropped exam 4):

Exam 1 + Exam 2 + Exam 3 + Final Exam + Lab = Total Score (one exam dropped)
 100 + 100      + 100 + 200          + 100 = 600

An approximate grade range for exam scores will be announced after each exam. Keep in mind that the course is graded
on a curve, so the absolute grades will be dependent on the dropped exams, as well as the scores on the lab components.
Cheating is a serious offense that will NOT BE TOLERATED on any exam or homework assignment and will be dealt
with severely according to University policy.

University Holidays
There are no lecture, labs, or discussion during University holidays. These days are: Monday, Jan 21st, Monday, Feb
18th, and the week of March 17th-21st.

                                  Elementary Bioorganic Chemistry (Chem 1120)
                                                   Spring 2008
                                              Dr. Alison Livingston
                                                Weekly Syllabus

Week Of: Chapter Topic
    7-Jan    13   alkenes and alkynes, cis/trans isomers, naming, properties
             13   organic rections, polymers, alcohols - naming, properties, and reactions
   14-Jan    14   aromatic compounds; phenols - acidity, ethers; thiols and disulfides
   23-Jan    15   amines - classification, properties, basicity, amine salts
          Exam 1 Friday, Jan 25th: Exam 1 = Ch 13, 14, and 15
   28-Jan    16   carbonyl groups; naming and properties of aldehydes and ketones; redox reactions
    4-Feb    17   carboxylic acids: naming and properties, acidity, esters and amides, reactions
             18   amino acids and amidation reaction; basic protein structure
   11-Feb 18 + 19 protein structure and chemical properties, basic enzymes
             19   enzymes, enzyme regulation and vitamins
          Exam 2 Friday, Feb 15th: Exam 2 = Ch 16, 17, 18, and 19
   20-Feb    20   hormones and chemical messengers; drug discovery and design
   25-Feb    21   overview of energy and metabolism, citric acid cycle, redox covators, electron transport, ATP
             22   carbohydrates - structure, cyclization, redox properties
    3-Mar    23   carbohydrate metabolism
   10-Mar Exam 3 Monday, Mar 10th: Exam 3 = Ch 20, 21, 22, and 23
             24   lipids - structure, classification, fatty acids and esters
   24-Mar 24 + 25 cell membranes and membrane transport
             25   lipid metabolism and ketone bodies
   31-Mar    26   basic nucleic acid chemistry, DNA and RNA structure, protein synthesis
    7-Apr Exam 4 Monday, April 7th: Exam 4 = Ch 24, 25, and 26
             27   Genomics: recombinant DNA and techniques
   14-Apr    27   DNA mutations, diseases, and polymorphisms
             28   Protein and amino acid metabolism, essential and non-essential amino acids
   21-Apr 13-28 Review for Final Exam (Ch 13-28)
   30-Apr 13-28 Wednesday, April 30: Final Exam: 8-10AM in HEB 2008 (Chapters 13-28)

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