Gastric cancer

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					       Gastric Cancer

Dr. Belal Hijji, RN, PhD
February 1, 2012
                Learning Outcomes

At the end of this lecture, students will be able to:
• Explain the pathophysiology of gastric cancer and its
   clinical picture.
• Describe assessment and diagnostic evaluation of
   gastric cancer.
• Discuss the medical management of gastric cancer.
• Discuss the nursing process for the care of a patient with
   gastric cancer.


• Gastric cancers can occur anywhere in the stomach.
  However, most frequently, they occur on the lesser
  curvature (next slide).
• The tumor infiltrates the surrounding mucosa,
  penetrating the wall of the stomach and adjacent organs
  and structures.
• At the time of diagnosis, the liver, pancreas, esophagus,
  and duodenum are often affected.

               Clinical manifestations
• Pain relieved by antacids.
• Dyspepsia (indigestion), early satiety
  (‫ ,)تخمة‬weight loss, abdominal pain
  above the umbilicus.
• Loss of appetite and nausea and

     Assessment and diagnostic findings
• The physical examination may not be helpful in detecting
  the cancer because most early gastric tumors are not
  palpable. In advanced cases, a gastric mass may be
• Ascites and hepatomegaly may be apparent if
  metastasis occurs.
• Palpable nodules around the umbilicus (slide 6).
• Esophagogastroduodenoscopy for biposy and cytologic
  washings is the diagnostic study of choice.
• CT completes the diagnostic studies to assess for
  surgical resectability of the tumor before surgery is
• CT of the chest, abdomen, and pelvis is important in
  staging of gastric cancer.                              5
Sister Mary Joseph's nodule of the umbilicus   6
               Medical management
• Successful treatment of gastric cancer is through tumor
• Cure could be achieved if the tumor has been removed
  while it is still localised to the stomach. Otherwise, cure
  is less likely.
• Unresectable tumor in a patient with advanced disease,
  chemotherapy using single agent chemotherapeutic
  medications including 5-fluorouracil (5-FU), cisplatin,
  doxorubicin, and mitomycin.
• It is now more common to administer combination
  therapy, primarily 5-FU-based therapy with other agents.

• Total gastrectomy may be performed for a resectable
  cancer. The entire stomach, the duodenum, the lower
  portion of the esophagus, supporting mesentry, and
  lymph nodes are removed. Esophagojejunostomy is
  performed to reconstruct the GI tract.

                Nursing process
         For a patient with gastric cancer

• Ask patient about loss of weight, how much and over
  what period of time. Ask about tolerating full diet. If not,
  what foods s(h)e eats. Does the patient feel full after
  eating small amount? Is there any pain? Do foods,
  antacids, or medications relieve pain? The nurse should
  then perform the physical examination to assess the
  abdomen for tenderness or masses, palpates the
  abdomen to detect ascites.

         Nursing diagnoses, planning and goals
• Based on assessment data, nursing diagnoses may
   –   Anxiety related to the disease and anticipated treatment.
   –   Imbalanced nutrition related to early satiety or anorexia.
   –   Pain related to tumor mass.
   –   Anticipatory grieving related to diagnosis of cancer.
   –   Deficient knowledge regarding self-care activities.
• The major goals for the patient may include:
   –   reduced anxiety
   –   optimal nutrition
   –   pain relief
   –   adjustment to diagnosis and anticipated life style changes
                    Nursing interventions
• Reducing anxiety:
   – Provide a relaxed, nonthreatening atmosphere so that the
     patient freely expresses his fears, concerns, and possibly
     anger about diagnosis.
   – Encourage significant others to support the patient.
   – Advise the patient about any procedures and treatments so
     that he knows what to expect.
• Promoting optimal nutrition:
   – Encourage the patient to eat small frequent portions of
     nonirritating foods that are high in calories and vitamins (A, C)
     and iron to enhance tissue repair.
   – Provide parenteral nutrition if prescribed before surgery.

– Explain ways to prevent and manage dumping syndrome
  (rapid emptying of the stomach contents into the small
  intestine; characterized by sweating and weakness) after
  surgery. In this condition, the patient has a feeling of fullness,
  nausea, and diarrhea; this causes dehydration, hypotension,
  and tachycardia. Therefore:
   • Encourage the patient to have six small meals daily that are low
     in carbohydrate and sugar with fluids between, rather than with,
     meals. Inform the patient that symptoms will often resolve after
     several months.
– Monitor the IV therapy and nutritional status.
– Record intake and output and daily weight.
– Assess for signs and symptoms of dehydration.

• Relieving pain:
   – Administer analgesics as prescribed
   – Assess the level of pain
   – Encourage nonpharmacologic methods for pain relief.
• Providing psychosocial support:
   – Help the patient express fear, concern, and grief about
   – Answer the patient’s questions honestly, and encourage him
     to participate in the treatment decisions.
   – Offer emotional support and involve significant others.

Expected outcomes may include the following:
• Reports less anxiety
• Attains optimal nutrition
• Has less pain
• Performs self care activities and adjust to lifestyle
• Prepares for the dying process


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