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• Government representatives at the state,
  local, and national levels must make
  decisions on a daily basis that they feel
  are for the good of the people.
• They must make informed decisions.
• One issue that they have to debate is
          What is cloning?
• Cloning: A form of reproduction in which
  offspring result not from the chance union
  of egg and sperm (sexual reproduction)
  but from the deliberate replication of the
  genetic makeup of another single
  individual (asexual reproduction).
               Human cloning
• Human cloning: The asexual production of a new
  human organism that is, at all stages of development,
  genetically virtually identical to a currently existing or
  previously existing human being.

• It would be accomplished by introducing the nuclear
  material of a human somatic cell (donor) into an
  oocyte (egg) whose own nucleus has been removed
  or inactivated, yielding a product that has a human
  genetic constitution virtually identical to the donor of the
  somatic cell. (This procedure is known as "somatic cell
  nuclear transfer," or SCNT).
    Reasons (uses) for human
• To produce children
• For biomedical research
Human embryo cloning:
Stem cells-biomedical research
 Cloning to produce children
• Cloning-to-produce-children: Production of
  a cloned human embryo, formed for the
  (proximate) purpose of initiating a
  pregnancy, with the (ultimate) goal of
  producing a child who will be genetically
  virtually identical to a currently existing
  or previously existing individual.
• Cloning-for-biomedical-research:
  Production of a cloned human embryo,
  formed for the (proximate) purpose of
  using it in research or for extracting its
  stem cells, with the (ultimate) goals of
  gaining scientific knowledge of normal
  and abnormal development and of
  developing cures for human diseases.
What are stem cells and why are
       they important?
• Stem cells are primal cells common to all
  multi-cellular organisms that retain the
  ability to renew themselves through cell
  division and can differentiate into a wide
  range of specialized cell types.
• In a developing embryo, stem cells are
  able to differentiate into all of the
  specialized embryonic tissues.
• stem cells can be readily grown
         Purpose of lesson
1. Students will illustrate comprehension of the
  issues involved with human cloning and its
  effects on society
2. Students will practice scientific inquiry to
  make an informed decision for or against

  How will they be accomplished?
  Students will research and discuss human
            cloning issues
        Issues to consider:
• Ethical issues (moral outcomes of cloning)
• Legal issues (how the government can
  regulate it)
• Social issues (impact on society as a
   Problem of investigation:
• Should the government legalize human
  cloning in our society (US)

• Think in your mind: Based on what you
  know about human cloning, do you
  support or reject legalization of human
• After the discussion, you will relay your
  stance on human cloning
• Using the knowledge and information you
  obtain about cloning:
  – You will write an persuasive letter to your
    senator explaining whether you support or
    oppose legalizing human cloning and why?
    (using inquiry and reasoning skills)
  – Your essay will be 1 full page
  – Start on the first line (do not skip)
  – Finish on the last line
  – Must have at least 9 words/line or 225 words
            Embryonic stem cells
• Embryonic stem
  cell lines (ES cell
  lines) are cultures of
  cells derived from the
  epiblast tissue of the
  inner cell mass (ICM)
  of a blastocyst. A
  blastocyst is an early
  stage embryo -
  approximately 4 to 5
  days old in humans
  and consisting of 50-
  150 cells
       Questions to think about:
• Some questions to ponder.
• The questions raised here have no clear right or wrong answer.
  Instead, your response will depend on your own set of values, as
  well as the opinions of those around you.
• Who has the right to have children, no matter how they are
  created? Who doesn't? Why?
• Is human cloning "playing with nature?" If so, how does that
  compare with other reproductive technologies such as in vitro
  fertilization or hormone treatments?
• Does cloning to create stem cells, also called therapeutic
  cloning, justify destroying a human embryo? Why, or why not?
• If a clone originates from an existing person, who is the
• What are some of the social challenges a cloned child might
• Do the benefits of human cloning outweigh the costs of human
• Should cloning research be regulated? How, and by whom?
• 2 ½ page double spaced report on the benefits and
  drawbacks of human cloning
• 1-inch margins at with 12 pt. times roman font
• 1st line of page 1 (1 page) Benefits of Human
• 1st line of page 2-(1 page) Drawbacks of Human
• 1st line of page 3-Government relation on       Human
        Cloning (½ page)-Argue whether it should or should
        not be regulated by the government?
• Do not skip lines-start the report directly under the title

   Test grade!

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