PHRM 203 - General Pharmacology

Maui Community College Course Outline 1. Alpha and Number Pharmacology 203 PHRM 203 General Pharmacology 3 credits October 2006 Course Title Credits Date of Outline 2. Course Description Discusses drugs with emphasis on sites and mechanisms of action, toxicity, fate, and uses of major therapeutic agents. 3. Contact Hours 3 cr., 3 hr lect. 4. Prerequisites Corequisites ZOOL 141, BIO 141, BIO 243, or consent Recommended Preparation Approved by _____________________________________ Date _______________ 5. General Course Objectives Describe mechanisms of drug action body impact of body processes on individual responses to drugs. State therapeutic use for each drug classification, describe common complications, and drug interactions. The following Maui Community College Student Learning Outcomes are a focus of the course 2.1 3.1 3.2 3.3 3.5 5.4 5.5 5.6 Apply numeric, graphic, and symbolic skills and other forms of quantitative reasoning accurately and appropriately. Use print and electronic information technology ethically and responsibly. Demonstrate knowledge of basic vocabulary, concepts and operations of information retrieval and technology. Recognize, identify and define an information need. Create, manage, organize and communicate information through electronic media. Recognize and understand multiple modes of inquiry, including investigative methods base on observation and analysis. Evaluate a problem, distinguishing between relevant, irrelevant facts, opinions, assumptions, issues, values, and bias, through the use of appropriate evidence. Apply problem-solving techniques and skills, including the rules of logic and logical sequence. Synthesize information from various sources, drawing appropriate conclusions. 5.7 6. Student Learning Outcomes For assessment purposes, these are linked to Course Content. Upon successful completion of this course, students will be able to: a. b. c. d. e. f. g. h. i. j. k. Describe basic mechanisms of drug action. Describe mechanisms by which the body processes medications from ingestion to metabolism and elimination Demonstrate how differences between individuals affect their response to drugs. State the therapeutic uses for each drug group. Identify frequent complications associated with different drug classes. Predict side effects of drugs classes and how to deal with them. Identify clinically significant drug interactions. List dosage forms of commonly used medications and be able to communicate to patients how to use these dosage forms effectively. Identify the potential effects of co-morbidities with other organ systems on the qualitative and quantitative effects of drugs. Explain how special populations are likely to respond to drugs and apply this information to appropriate administration of said drugs. Identify how guidelines for disease state management influence drug prescribing and administration. 7. Course Content and Time Spent on Each Topic Linked to Student Learning Outcomes. Introduction to pharmacology, receptors, kinetics,and Biotransformation a, b Week 2 Drugs affecting autonomic nervous system, Cholinergics drugs, Anticholinergics drugs c, d, e, f, g, h, I, j, k Week 3 & 4 Adrenoceptor agonist and antagonist drugs c, d, e, f, g, h, I, j, k Treatment of Hypertension, Angina, Heart Failure c, d, e, f, g, h, I, j, k Week 1 Week 5 Use of Diuretics, Histamine, prostaglandins, leucotrienes, Treatment of Asthma c, d, e, f, g, h, I, j, k Week 6 & 7 Use of Sedative Hypnotics, Antiepileptics, General and local anesthetics c, d, e, f, g, h, I, j, k Week 8 Skeletal muscle relaxants, Treatent of Parkinsons Disease, Use of Antipsychotics, Antidepressants, c, d, e, f, g, h, I, j, k Week 9 Use of opioids, anticoagulants, Treatment of Hyperlipidemia, NSAIDS c, d, e, f, g, h, I, j, k Week 10 & 11Hypothalamic and Pituitary hormones, Thyroid, Adrenocorticosteroids,Gonadal hormones, c, d, e, f, g, h, I, j, k Week 12 Treatment of diabetes, bone mineral homeostasis Week 13 Antibiotics, tuberculosis c, d, e, f, g, h, I, j, k Week 14 Atifungals, Antivirals, Antiprotozoals, Antiparasitics c, d, e, f, g, h, I, j, k Week 15 Use of Antiparasitics, Cancer chemotherapy, misc topics c, d, e, f, g, h, I, j, k 8. Text and Materials Katzung, B, Basic and Clinical Pharmacology , 9th edition, 2005. 9. Recommended Course Requirements and Evaluation 4 Exams and final exam (each exam is 18% of course grade) Home work – discussion topics 10% 10. Methods of Instruction 1. Learning objectives 2. Focused on-line discussion 3. Reading references 4. Resource WEBSITES 5. Demonstrations 6. Audio-visual aids 7. Exams 9. WEBCT learning materials and assignments

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