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Polypeptides Having Endoglucanase Activity And Polynucleotides Encoding Same - Patent 8143482

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Polypeptides Having Endoglucanase Activity And Polynucleotides Encoding Same - Patent 8143482 Powered By Docstoc
					
				
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Description: REFERENCE TO A SEQUENCE LISTING This application contains a Sequence Listing in computer readable form. The computer readable form is incorporated herein by reference.REFERENCE TO A DEPOSIT OF BIOLOGICAL MATERIAL This application contains a reference to deposits of biological material which have been made at the Northern Regional Research Center (NRRL) under the Budapest Treaty and assigned accession numbers NRRL B-30900N, NRRL B-30902, NRRL B-30903, andNRRL B-30904, which microbial deposits are incorporated herein by reference.BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising thepolynucleotides as well as methods for producing and using the polypeptides. 2. Description of the Related Art Cellulose is a polymer of the simple sugar glucose covalently bonded by beta-1,4-linkages. Many microorganisms produce enzymes that hydrolyze beta-linked glucans. These enzymes include endoglucanases, cellobiohydrolases, and beta-glucosidases. Endoglucanases digest the cellulose polymer at random locations, opening it to attack by cellobiohydrolases. Cellobiohydrolases sequentially release molecules of cellobiose from the ends of the cellulose polymer. Cellobiohydrolase I is a1,4-beta-D-glucan cellobiohydrolase (E.C. 3.2.1.91) activity which catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, cellotetriose, or any beta-1,4-linked glucose containing polymer, releasing cellobiose from the reducing ends ofthe chain. Cellobiohydrolase II is a 1,4-D-glucan cellobiohydrolase (E.C. 3.2.1.91) activity which catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, cellotetriose, or any beta-1,4-linked glucose containing polymer, releasingcellobiose from the non-reducing ends of the chain. Cellobiose is a water-s