Integration Of Fluids And Reagents Into Self-contained Cartridges Containing Sensor Elements And Reagent Delivery Systems - Patent 8101431

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Integration Of Fluids And Reagents Into Self-contained Cartridges Containing Sensor Elements And Reagent Delivery Systems - Patent 8101431 Powered By Docstoc
					
				
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Description: BACKGROUND 1. Field of the Invention The present invention generally relates to a method and device for the detection of analytes in a fluid. More particularly, the invention relates to a portable apparatus for obtaining analytical information using both membrane- andparticle-based detectors. 2. Description of Related Art Current methodology used to complete medical diagnostics, environmental monitoring, and detection of bioterrorism-related agents often require large and expensive instruments and highly specialized personnel found only in certain hospitals,laboratories or government agencies. Furthermore, these instruments are often restricted to a limited number of applications. For example, in the area of medical diagnostics, each instrument is very specialized and designed either to measure proteinlevels or to analyze cellular matter but, typically, may never do both. Additionally, each system is capable of analyzing only a few of the relevant markers of a disease, therefore adding another component to an already tedious and time consumingprocess that can vary from hours to days. Long delays can be generated between the time of the initial visit, diagnosis, and administration of treatment, potentially having detrimental effects on the prognosis of the disease. Similarly, timelyidentification of an unknown environmental or deliberately introduced contaminant is crucial. For example, two of the envelopes from the 2001 anthrax attacks were processed at a facility that remained open for 9 days after the initial contamination,exposing more than 60 million mail items and more than 2000 employees to Bacillus anthracis spores. It is therefore desirable that new methods and systems capable of discriminating analytes and/or microbes be developed for health and safety, environmental, homeland defense, military, medical/clinical diagnostic, food/beverage, and chemicalprocessing applications. It is further desired that the methods and systems facilitate rapid scree