A Look Through Time
For this assignment you will use the following timeline to answer questions 1 and 2.
Before answering the questions, be sure to click on each year of the timeline.
To answer question 3 you will need to find credible resources dealing with the
topic on the internet. This assignment is to be turned in on paper.
1. Why is it possible to eliminate a disease like smallpox but not tetanus?
2. Compare Dr. RRK’s children’s immunization records which can be found within
the timeline. For each child list the ages that they received the Hepatitis B
vaccine as well as the Chicken Pox (Varicella) vaccine. What accounts for the
differences you see in the ages they received them? Are there any vaccines
that one child has that another doesn’t, and WHY?
3. Write a paragraph discussing the conditions surrounding the retraction of the
Rotavirus vaccine from the market. Can you find specifics as to why the
Rotavirus vaccine was initially sent out into the market and then later pulled?
Pertussis 1935 1945 1952
Yellow Influenza Polio
1964 Hepatitis B
• MMR (tri-valent measles/mumps/rubella)
• U.S. ended routine use of smallpox
See also 1796 , 1905 , 2003
1992 Pox 1998
Immunization 1997 Smallpox
Back to the start
• Chicken Pox vaccine licensed and put into
wide spread use.
See also 1974
• Smallpox vaccine stored in emergency
first responder med-kits.
See also 1796 , 1905 , 1972
• Rotavirus vaccine pulled off market due to
significant adverse reactions.
• First vaccine for Rotavirus
Structure of rotavirus obtained by
electron cryomicroscopy and
computer image processing.
• First vaccine for
• First vaccine for Haemophilus influenzae B
• First vaccine for
• First vaccine for Pneumonia
• First vaccine for Chicken Pox (Varicella)
See also 1995
• First vaccine for Rubella
• First vaccine for Mumps
• First vaccine for Measles
• First vaccine for Polio
• First vaccine for Influenza
• First vaccine for Typhus
• First vaccine for Yellow Fever
• First vaccine for Tuberculosis
• First vaccine for Pertussis or the
• First vaccine for Tetanus
• First vaccine for Diphtheria
• Tetanus is a disease caused by the toxin
of the bacterium Clostridium tetani that
affects the central nervous system,
sometimes resulting in death. Spores of
the bacterium Clostridium tetani live in the
soil and are found around the world. In the
spore form, C. tetani may remain dormant
in the soil, and it can remain infectious for
more than 40 years.
• First vaccine for the Plague
• First vaccine for Rabies
• First vaccine for Anthrax
• First vaccine for Cholera
• Smallpox vaccine is created, the first
vaccine for any disease.
See also 1905 , 1972 , 2003
• In 1905 the US Supreme Court upholds
state law mandating smallpox vaccinations
See also 1796 , 1972 , 2003
• Smallpox is a viral disease unique to
humans. It is caused by the variola virus.
To sustain itself, the virus must pass from
person to person in a continuing chain of
infection and is spread by inhalation of air
droplets or aerosols.
• Smallpox information
• Tetanus information
• Vaccine timeline information
– Microsoft health clipart collection on-line