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					Vaccine Timeline




  A Look Through Time

                        START
Instructions:
For this assignment you will use the following timeline to answer questions 1 and 2.
   Before answering the questions, be sure to click on each year of the timeline.
   To answer question 3 you will need to find credible resources dealing with the
   topic on the internet. This assignment is to be turned in on paper.
1. Why is it possible to eliminate a disease like smallpox but not tetanus?
2. Compare Dr. RRK’s children’s immunization records which can be found within
   the timeline. For each child list the ages that they received the Hepatitis B
   vaccine as well as the Chicken Pox (Varicella) vaccine. What accounts for the
   differences you see in the ages they received them? Are there any vaccines
   that one child has that another doesn’t, and WHY?
3. Write a paragraph discussing the conditions surrounding the retraction of the
   Rotavirus vaccine from the market. Can you find specifics as to why the
   Rotavirus vaccine was initially sent out into the market and then later pulled?




                                                                       To Timeline
                 1881
                Anthrax                     1897
                                           Plague
 1796                                                1905
Smallpox                                            Smallpox




                     1882
                     Rabies
            1879
                                1890
           Cholera
                               Tetanus
                              Diphtheria
  1926
Pertussis       1935              1945      1952

                Yellow          Influenza   Polio
                Fever




                         1937
     1927            Typhus

 Tuberculosis
          1967
          Mumps
                   1970                          1981
 1964                                          Hepatitis B
                  Rubella            1977
Measles
                                   Pneumonia




                            1972
                        Smallpox
                               1974
                     1971
                           Chicken Pox
                     MMR
                 1971
• MMR (tri-valent measles/mumps/rubella)
  licensed.
                  1972
• U.S. ended routine use of smallpox
  vaccine

See also 1796 , 1905 , 2003
                  1995
1985
               Chicken
HiB                                                             Today
          1992  Pox           1998
                                              2001           Immunization
          Alex’s            Rotavirus
                                             Katie’s           standards
       Immunization
                                           Immunization




                                 1999
              1994
                               Rotavirus             2003
              Max’s
           Immunization 1997                      Smallpox

                        Zach’s
                      Immunization

                                                     Back to the start
                  1995
• Chicken Pox vaccine licensed and put into
  wide spread use.

See also 1974
                  2003
• Smallpox vaccine stored in emergency
  first responder med-kits.

See also 1796 , 1905 , 1972
2001




       Katie’s Immunization
                  1999
• Rotavirus vaccine pulled off market due to
  significant adverse reactions.
                           1998
• First vaccine for Rotavirus


                              Structure of rotavirus obtained by
                              electron cryomicroscopy and
                              computer image processing.




   http://www.bcm.tmc.edu/biochem/
   biochem_images.html
              1994

Max with
baby Katie




             Max’s immunization
    1997




Zach’s Immunizations
                      1992
• First vaccine for
  Hepatitis A




                             Alex’s immunizations
                  1985
• First vaccine for Haemophilus influenzae B
  (HiB)
                      1981
• First vaccine for
  Hepatitis B
                  1977
• First vaccine for Pneumonia
                   1974
• First vaccine for Chicken Pox (Varicella)

See also 1995
                   1970
• First vaccine for Rubella
                  1967
• First vaccine for Mumps
                  1964
• First vaccine for Measles
                    1952
• First vaccine for Polio
                   1945
• First vaccine for Influenza
                   1937
• First vaccine for Typhus
                   1935
• First vaccine for Yellow Fever
                   1927
• First vaccine for Tuberculosis
                   1926
• First vaccine for Pertussis or the
  Whooping Cough
                   1890
• First vaccine for Tetanus

• First vaccine for Diphtheria
                 Tetanus
• Tetanus is a disease caused by the toxin
  of the bacterium Clostridium tetani that
  affects the central nervous system,
  sometimes resulting in death. Spores of
  the bacterium Clostridium tetani live in the
  soil and are found around the world. In the
  spore form, C. tetani may remain dormant
  in the soil, and it can remain infectious for
  more than 40 years.
                   1897
• First vaccine for the Plague
                    1882
• First vaccine for Rabies
                   1881
• First vaccine for Anthrax
                   1879
• First vaccine for Cholera
                   1796
• Smallpox vaccine is created, the first
  vaccine for any disease.

See also 1905 , 1972 , 2003
                  1905

• In 1905 the US Supreme Court upholds
  state law mandating smallpox vaccinations

See also 1796 , 1972 , 2003
                Smallpox
• Smallpox is a viral disease unique to
  humans. It is caused by the variola virus.
  To sustain itself, the virus must pass from
  person to person in a continuing chain of
  infection and is spread by inhalation of air
  droplets or aerosols.
                           References
•   Smallpox information
     – http://www.bt.cdc.gov/agent/smallpox/overview/disease-facts.asp
     – http://www.cdc.gov/ncidod/EID/vol5no4/henderson.htm
•   Tetanus information
     – http://www.uhseast.com/14545.cfm
•   Vaccine timeline information
     – http://www.909shot.com/Timeline/timeline.htm
     – http://en.wikipedia.org/wiki/Timeline_of_vaccines
•   Images
     – http://www.idph.state.il.us/about/vpcd.htm
     – Microsoft health clipart collection on-line

				
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posted:4/12/2012
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