; Chronic Cigarette Smoking Alters Circulating Sex Hormones and Neuroactive Steroids in Premenopausal Women
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Chronic Cigarette Smoking Alters Circulating Sex Hormones and Neuroactive Steroids in Premenopausal Women

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[...] only little attention was paid to neurosteroids (known as potent modulators of type A GABA receptors (GABAA-r) and NMDA receptors (NMDA-r)) in these subjects. [...] we attempted to establish whether the pattern of circulating neuroactive steroids, their precursors and metabolites (Figures 1 and 2), differs between premenopausal smokers and age-matched non-smokers in the follicular (FP) and luteal phases (LP) of the menstrual cycle.

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									Physiol. Res. 61: 97-111, 2012




Chronic Cigarette Smoking Alters Circulating Sex Hormones
and Neuroactive Steroids in Premenopausal Women

M. DUŠKOVÁ1, K. ŠIMŮNKOVÁ1, M. HILL1,4, M. VELÍKOVÁ1, J. KUBÁTOVÁ1,
L. KANCHEVA1, H. KAZIHNITKOVÁ1, H. HRUŠKOVIČOVÁ1, H. POSPÍŠILOVÁ1,
B. RÁCZ1, M. SALÁTOVÁ1, V. CIRMANOVÁ1, E. KRÁLÍKOVÁ2,3, L. STÁRKA1,
A. PAŘÍZEK4
1
 Institute of Endocrinology, Prague, Czech Republic, 2Institute of Hygiene and Epidemiology, First
Faculty of Medicine, Charles University, Prague, Czech Republic, 3Tobacco Dependence Treatment
Centre, Third Medical Department – Department of Metabolism and Endocrinology, First Faculty
of Medicine, Charles University, Prague, Czech Republic, 4Department of Obstetrics and
Gynecology of the First Faculty of Medicine, Charle
								
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