Biochip Array Technology by Av2aOdBt

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									Biochip Array Technology



   Randox Laboratories Ltd
          Aim of Biochip Array
            Technology
•   Achieve high throughput
•   Enable complete patient profiling
•   Ensure rapid and accurate diagnosis
•   To be efficient, accurate and cost effective
The Biochip
      • Solid-state device
      • Discrete test regions
      • Allows multiple
        assays to be
        performed
        simultaneously
      • Utilises basic ELISA
        principles
Discreet Testing Regions
Non-activated Surface
Activated Surface
                      Panels Available
                         • Cytokine Array I, IV, V*
                       • Adhesion Molecule Array
                           • Tumour PSA Array
                      • Drugs of Abuse Array I, II
                              • Cardiac Array
                              • Fertility Array
                           • Free Thyroid Array
                           • Total Thyroid Array
                        • Growth Promoter Array*
                          • Anti-Microbial Array*
                      • Ranplex CRC DNA Array*
                             • Cerebral Array*
* Investigator only
                       Operator Input
  Instructions entry
                          Reagent/sample
Sample/reagent loading                         Incubator
                          addition station
   Carrier loading

      Operator steps
                                             Wash station
      Analyser steps


  Biowaste disposal       Imaging station    Signal station
     Investigator Kit Components
•   6 biochip carriers
•   9 levels of multi-analyte calibrators
•   Assay diluent
•   Multi-analyte conjugate
•   Wash buffer concentrate
•   Signal reagent
•   Calibrator concentration update data
    Investigator Systems Package
•   Imaging Module (CCD Camera)
•   Full PC with Printer
•   Dedicated Software
•   Thermo-Shaker
•   Barcode Scanner
•   6 Carrier Holder
             Automated Steps
Instructions entered
                       Reagent/sample
  Samples loaded                                   Incubator
                       addition station
 Reagents loaded

                                Sandwich Assays
                                                  Wash station
   Operator steps
   Analyser steps


Biowaste disposal      Imaging station            Signal station
    Features of Biochip Array
          Technology
• Simultaneous, multi-analyte screening
• Reduced sample volume:
  – 7μl to 60μl required for drugs of abuse
• Reduction in QC material: multi-analyte
  controls, cost savings
• Snapshot of results: no issues with
  stability, more accurate diagnosis
    Features of Biochip Array
          Technology
• On board QC facilities
  – Levey Jennings
  – Multipoint Rules
• Multi-format search options:
  – Panel, user, date, sample code
• Technical expertise and excellent support
     Features of Biochip Array
           Technology
• Calibrators – 9 level, 4 parameter curve fit,
  update CD in kit
• Control serum available
• Retrospective and reflex testing
• Evidence: lab only invoiced for reported
  tests – costs decrease as more tests are
  reported
    Features of Biochip Array
          Technology
• Straightforward protocol: saves time and
  reduces errors
• Full traceability through manufacture
• No hidden costs: full system supplied
• Reduction in storage space and
  associated costs
     Advantages of Evidence
          Technology
• Software
  – user interface operator friendly and flexible –
    Windows XP, colour coding
  – dedicated report format for each panel
  – profiles can be created and stored
  – selection of tests from panel
  – Selection of search options: panel, user, date, sample
    code
  – Enhanced trouble shooting Error Codes
                   Conclusion
abc
• leading the way in Protein Biochip Array Technology
  and its use in diagnostic medicine!


Biochip Array technology:
         The next step forward in
          Immunoassay testing!

								
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