VIEWS: 54 PAGES: 19 POSTED ON: 3/25/2012
Biochip Array Technology Randox Laboratories Ltd Aim of Biochip Array Technology • Achieve high throughput • Enable complete patient profiling • Ensure rapid and accurate diagnosis • To be efficient, accurate and cost effective The Biochip • Solid-state device • Discrete test regions • Allows multiple assays to be performed simultaneously • Utilises basic ELISA principles Discreet Testing Regions Non-activated Surface Activated Surface Panels Available • Cytokine Array I, IV, V* • Adhesion Molecule Array • Tumour PSA Array • Drugs of Abuse Array I, II • Cardiac Array • Fertility Array • Free Thyroid Array • Total Thyroid Array • Growth Promoter Array* • Anti-Microbial Array* • Ranplex CRC DNA Array* • Cerebral Array* * Investigator only Operator Input Instructions entry Reagent/sample Sample/reagent loading Incubator addition station Carrier loading Operator steps Wash station Analyser steps Biowaste disposal Imaging station Signal station Investigator Kit Components • 6 biochip carriers • 9 levels of multi-analyte calibrators • Assay diluent • Multi-analyte conjugate • Wash buffer concentrate • Signal reagent • Calibrator concentration update data Investigator Systems Package • Imaging Module (CCD Camera) • Full PC with Printer • Dedicated Software • Thermo-Shaker • Barcode Scanner • 6 Carrier Holder Automated Steps Instructions entered Reagent/sample Samples loaded Incubator addition station Reagents loaded Sandwich Assays Wash station Operator steps Analyser steps Biowaste disposal Imaging station Signal station Features of Biochip Array Technology • Simultaneous, multi-analyte screening • Reduced sample volume: – 7μl to 60μl required for drugs of abuse • Reduction in QC material: multi-analyte controls, cost savings • Snapshot of results: no issues with stability, more accurate diagnosis Features of Biochip Array Technology • On board QC facilities – Levey Jennings – Multipoint Rules • Multi-format search options: – Panel, user, date, sample code • Technical expertise and excellent support Features of Biochip Array Technology • Calibrators – 9 level, 4 parameter curve fit, update CD in kit • Control serum available • Retrospective and reflex testing • Evidence: lab only invoiced for reported tests – costs decrease as more tests are reported Features of Biochip Array Technology • Straightforward protocol: saves time and reduces errors • Full traceability through manufacture • No hidden costs: full system supplied • Reduction in storage space and associated costs Advantages of Evidence Technology • Software – user interface operator friendly and flexible – Windows XP, colour coding – dedicated report format for each panel – profiles can be created and stored – selection of tests from panel – Selection of search options: panel, user, date, sample code – Enhanced trouble shooting Error Codes Conclusion abc • leading the way in Protein Biochip Array Technology and its use in diagnostic medicine! Biochip Array technology: The next step forward in Immunoassay testing!
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