Children with Mild and Unilateral Hearing Impairment

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							                                     EDHI Feb 2004




     Children with Mild and
     Unilateral Hearing
     Impairment
     Current management and
     outcome measures
Kirsti Reeve Ph.D.
Developmental Disabilities Institute
Wayne State University, Detroit MI
Overview
 Current management for children with mild
  and unilateral hearing impairment (HI)
 Outcome measures:
     Speech  and language
     Cognition
Why these populations?
 Very little known about management or
  outcomes for mild or unilateral HI
 NHSP offers the potential for early
  identification
 There is strong evidence that early
  identification gives improved outcomes in
  moderate and greater HI populations
 Need to ascertain whether it would be
  appropriate for these groups
Study overview
   Two separate studies
     Questionnaire  survey to audiologists
      investigating management options
     Outcomes study
       Obtained epidemiological data
       Assessed impact of HI quality of life

       Assessed impact of HI on speech, language &
        cognition
Current management:
options for children with mild or
unilateral hearing impairment
Why assess service provision?
   Areas of uncertainty
     Numbers   of children being identified
     Age of identification
     Management options for these groups
     Level at which to provide hearing aids
How was it done?
 Single page questionnaire survey
 Sent out to 131 professionals
  throughout the UK
 1 reminder
 56 responses (43%)
    Results
   Information on the mild and unilateral
    cases seen

   Management offered to those cases
    Results
   Information on the mild and unilateral
    cases seen

   Management offered to those cases
Numbers of children with
bilateral mild impairment
   Defined as 20-40dBHL permanent
    sensorineural loss
   Comprise 8% of total caseload
   Range seen from 0 to 300 (mean of 25)
   Estimated total number seen by 56
    clinicians: 1220
Numbers of children with
unilateral hearing impairment
   Defined as permanent sensorineural
    loss in one ear only.
   Comprise 4% of total caseload

   Range seen from 0 to 40 (mean of 9)

   Estimated total number seen by 56
    clinicians: 443
Numbers of children seen
 N
     25
                                                                     Mild
                                                                     Unilateral
     20



     15



     10



      5



      0
          0   1-5   6-10   11-15    16-20    21-25   26-30   31-35      36+
                                   Numbers
Numbers found
   Literature estimates prevalence figures at:
     between 0.5-5.2% for unilateral impairment
     Between 1 and 5.4% for mild impairment


   “It is well recognized that an inverse relationship
    exists between the prevalence and degree of
    hearing loss” – Bess 1984

   The low percentage as ascertained by this
    questionnaire would imply that large numbers of
    these populations are not receiving audiological
    management
Age of Referral

    N
        35
                                                              Mild
        30                                                    Unilateral

        25

        20

        15

        10

         5

         0
             0-6 months 6-12 months   1-3 years   4-6 years   6 years +
                                        Age
Age of referral, data from Trent Region
(Mild n=50, Unilateral = 30)
        percentiles
  100
   90                                                                                                                     X


   80                                             
                                                           
                                                                                                      X

   70                                                                          
                                                                                 X

   60                                                                     X

   50                                                       X

   40                             X
                                                                                                             
                                                                                                               Moderate
                                                                                                              All Trent
   30             
                     ,                                                                                        Mild

   20        
                 ,                                                                                           X Unilateral

   10       
            
            ,
    0 
      ,
      '
      )
        0         10         20          30           40           50       60   70    80   90   100       110   120    130      140
                                                                            Age in months
Age of referral
 Age of referral is late for both groups of
  children when compared with Trent data
 Children with unilateral impairment
  identified significantly later than children
  with mild impairment
 Modal age of between 4 and 6 years
  suggests that the school entry is a factor
  leading to identification
    Results
   Information on the mild and unilateral
    cases seen

   Management offered to those cases
Management

                                                         Unilateral
            None/Discharge
                                                         Mild


            Speech Therapy


                   Review
  Options




                     Refer


                    Advice


                       Aid


                             0   10   20       30   40            50
                                       Frequency
Management
   Most frequent options are review and
    advice
   Children with mild HI are significantly more
    likely to be offered:
     Hearing  Aids (p=0.0005)
     Speech Therapy (p=0.003)
     Referral to other professional (p=0.022)
Provision of aids
 Uncertainty among professionals on
  whether to aid mild HI
 Level below which you would not consider
  providing aids:
     25dBHL   (range from 15 - 35dBHL)
   Level above which you would definitely
    provide aids:
     40dBHL   (range from 25 to 50dbHL)
Management conclusions
 Mild and unilateral HI are under-
  represented in the caseload of this sample
 These groups of children are identified
  later than children with more severe
  impairments
 Management is still uncertain whether to
  provide aids and at what level for children
  with a bilateral mild impairment
Outcome Measures –
Language and Cognition
Hypotheses
   Language is likely to be affected to some
    degree by a mild or unilateral hearing
    impairment

   There will be a positive relationship
    between language scores, non-word
    repetition and verbal reasoning
Subjects
    41 children from CHAC met study criteria:
      Aged   6-11
      Bilateral mild, or unilateral hearing impairment
      HI is sensorineural
      No associated syndromes, or other problems.
      No known learning or cognitive disabilities.
      English as first language


    20 children agreed to participate though one
     child DNA’d twice, and was not followed up a
     third time.
Participants
   8 mild
   11 unilateral
    6  mild, 3 moderate, 1 severe, 1 profound
     5 left ear impaired, 6 right ear

   5 girls, 14 boys
   Aged 6-11, average age 8yrs 3 months

   Age of identification ranged from 9 months to 6
    years 7 months (mean of 2 years 4 months)
Assessments
   The session consisted of:
     Computer   based test of sound lateralization
     Standardised language assessment (CELF-3
      UK)
     Children’s test of Non word Repetition
     BAS verbal & non-verbal reasoning (IQ)


   Most sessions lasted 90-120 mins
    including breaks.
Results
   Language

   Non-word repetition

   Cognition
Results
   Language

   Non-word repetition

   Cognition
Language testing - CELF 3 UK
    Standardised on UK population
      Six   subtests:
          3 for receptive language (understanding)
              Sentence Structure (aged 6-8) / Semantic
               Relationships (aged 9+)
              Concepts and Directions

              Word Classes

          3 for expressive language (speaking)
              Word Structure (6-8) / Sentence Assembly (9+)
              Formulated Sentences

              Recalling Sentences
Means of all language scores
           Standardised Test: mean:100, sd:15
         110
                                                                            Receptive Language
                                                                                Mean: 89.65,
                                                                                sd 13.18
         100
                                                                            Expressive Language
                                                                                Mean: 85.76,
                                                                                sd 13.51
         90
                                                                            Total Language
                                                                                Mean: 86.29,
                                                                                sd 14.01
         80
95% CI




         70
           N=            17                17                 17

                Receptive language s                 Total language score
                                   Expressive language
Total Language Scores for
individual subjects
      120



      110



      100



       90



       80



       70



       60

                 Unilateral HI                    Mild HI
            .5              1.0             1.5     2.0     2.5


             type of hearing i mpai rment
Speech & language results 1
   Unilateral group - total language score
    mean of 91.78

   Mild group - total language score mean of
    80.12

   With a linear regression, the difference in
    scores just misses significance (.089) -
    this could be due to the small sample size.
Speech & language results 2
   Converting scores to age equivalent gives
    an average language delays of:
    6  months for children with a unilateral
      impairment
     24 months for children with a mild impairment
Results
   Language

   Non-word repetition

   Cognition
Children’s Test of Non-word
Repetition
 Assesses phonological memory, and is
  predicative of literacy development
 Administered via computer




   Scores converted to standard scores,
    with a mean of 100, sd of 10
CN-Rep Results 1

   Both groups of children scored below
    100 on this task

     Children   with mild HI: mean= 87.75

     Children   with unilateral HI: mean=95.55
CN-Rep results by type of hearing
impairment
      110




      100




      90




      80




      70
        N=                      11          8

                            unilateral   bilateral


            type of hearing impairment
CN-Rep results 2
   Significant correlation of .953 with the
    recalling sentence CELF subtest (p=0.005)
    controlling for age

   Scores can be compared with those from
    an OME group and hearing controls from
    BOS study
CN-Rep scores as a function of type of
hearing impairment
                 115   110.7
                 110
                                105.2
                 105
standard score




                 100
                                                  95.6
                  95
                  90                                         87.8
                  85
                  80
                  75
                  70
                       None     OME             Unilateral   Mild
                               type of hearing impairment
Results
   Language

   Non-word repetition

   Cognition
Cognition
 Two tests from the British Abilities Scale
  (BAS)
 Similarities (verbal reasoning)
     Why     do these things go together:
          “milk, lemonade, coffee” , “cod, shark, pilchard”
     Need     to produce the superordinate

   Matrices (non verbal reasoning)
     Finish    the pattern
Cognition results 1
   Similarities (verbal reasoning)
     centile
            scores ranged from 17-84
     mean of 45.71, sd 20

   Matrices (non verbal reasoning)
     centile
            scores ranged from 29-99
     mean of 77.82, sd of 23.55

   So - significantly impaired scores on verbal
    reasoning (p<.001 on independent samples t-
    test)
Cognition results 2
   Only 3 children, all with mild HI, had higher
    verbal than non-verbal reasoning

   Mean difference of 32 centiles between
    verbal and non-verbal scores
   Significant difference in non-verbal score
    depending on type of HI
     Independent   samples t test gives p=0.027
Cognition results
            100




            80




            60




            40
                                                                   Similarities centile
   95% CI




            20                                                     matrices centile
              N=        9                9     8               8

                            unilateral             bilateral


                  type of hearing impairment
Cognition results 4
   Correlation of .625 between verbal
    reasoning and CELF language scores
    (p=0.003)

   Results can be compared across severity
    range with outcomes data from larger
    studies
     Reasoning scores as a function of type
     of hearing impairment
          70
                                                              Verbal
          60

          50
t-score




          40

          30

          20

          10

          0
               No




                      O




                            Un




                                        M




                                                         Se
                                               M




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                                         ild




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     Reasoning scores as a function of type
     of hearing impairment
          70
                                                               Verbal
          60

          50
t-score




          40

          30

          20

          10

          0
               No




                      O




                            Un




                                        M




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Outcome measures conclusions
The caveat -
 These children were all identified through
  CHAC. Therefore they have made it to the
  attention of the audiology services
 There may be ascertainment bias which
  could effect the results and make
  generalisation more difficult
Outcome measures conclusions
   Laterality of impairment for the unilateral
    group was not predictive of performance

   Greater severity of impairment was
    correlated with better performance on
    language outcomes ...

   … although numbers are very small
Outcome measures conclusions
   Children with mild or unilateral hearing HI who
    are known to audiology services could be at risk
    for developing language problems

   Children with a bilateral mild impairment are
    perhaps at greater risk than those with a
    unilateral impairment, regardless of severity
Overall conclusions
 Children with mild impairments are
  showing language deficits that may
  possibly be ameliorated through earlier
  identification
 There is a need for further research in the
  area of amplification provision for mild
  impairments
Overall conclusions
 Children with unilateral impairments
  showed a variable performance which was
  not correlated with severity of impairment
  or side of impairment
 There is the need for a larger study to
  investigate these findings further
 Early identification through NHSP is still
  recommended
Thanks to
 Adrian Davis and Sally Hind at MRC
  Institute of Hearing Research, Nottingham
 Paul Shaw and the staff at CHAC,
  Nottingham
 Helen Spencer & Jabulani Sithole for
  statistical assistance
 Medical Research Council for PhD funding
     Reasoning scores as a function of type
     of hearing impairment
          70
                                                          Non Verbal
          60

          50
t-score




          40

          30

          20

          10

          0
               No




                      O




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                                        M




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     Reasoning scores as a function of type
     of hearing impairment
          64
                                                          Non Verbal
          62

          60

          58
t-score




          56

          54

          52

          50

          48

          46
               No




                      O




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     Reasoning scores as a function of type
     of hearing impairment
          70                                                 Verbal
          60
                                                             Non Verbal

          50
t-score




          40

          30

          20

          10

          0
               N




                     O




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     Reasoning scores as a function of type
     of hearing impairment
          70                                                 Verbal
          60                                                 Non Verbal

          50
t-score




          40

          30

          20

          10

          0
               N




                     O




                          U




                                       M




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                                   l
Why does the prevalence
increase with age?
   Is it…
     new    cases (i.e. acquired losses)?

     progressive     nature of mild cases?

     late   onset?

     persistent   OME?

						
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