DNA Damage_ DNA Technologies_ Genetics Since Gregor Mendel

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					DNA Damage, DNA Technologies,
 Genetics Since Gregor Mendel
          11.15.2010 Catalyst:
1.What is the difference between genes and
  alleles? Please define each word, and give an
  example of each.
       Standards and Objectives
Standard:
I.I.I.2. Use models to explain the relationships
     between variables being investigated.

Content:
SWBAT: compare predicted results with expected
   results in a lab
Language:
SWBAT Write a paragraph describing the results of
   the experiment
                Modeling Inheritance
AGENDA:
                       11.15.2010
            :
             :
       : Explain Bean Lab
    : Explain Math concepts
      : Finish the lab and compare
  results
                None
           Hand in Lab
Opening


          = Black rabbit coat allele




                = Brown rabbit coat allele
Calculate Ratio:
             11.16.2010 Catalyst:
Monday:          Genes are parts of chromosomes
11.15.2010       that code for inherited traits
                 Alleles are different versions of a
                 gene.

Tuesday:         How many alleles for each gene do
11.16.2010       reproductive cells contain? Why?
         Standards and Objectives
Standard:
III.I.I.1. Analyze the contributions of science to health as they
      relate to personal decisions about smoking, drugs,
      alcohol, and sexual activity.

Content:
SWBAT: analyze a situation involving drugs, alcohol, and
   smoking, from a scientific point of view.

Language:
SWBAT Explain in writing what drugs, alcohol, and smoking
   can do to your cells (DNA damage).
 DNA Damage, Scientific Information about DRUGS

AGENDA:
                       11.16.2010
             :
            : Montana Meth Project
       : Notes about Drugs
    : Explain scientific evidence
      : Write a short answer question
               Short answer
          Hand in Lab
Opening
I. Drugs are substances that change
       normal bodily function
Behavioral or physical
      DRUGS DAMAGE DNA                              Date:

      I. Drugs are substances that change normal bodily function.
      II. All of the following illegal drugs damage DNA (can harm the
           person and/or the offspring)
            A. Can cause unconsciousness, vomiting, brain damage and
               death
                1. Examples: alcohol, heroin, marijuana
            B. Can cause seizures, headaches, paranoia, cancer, and death
                1. Examples: caffeine* (not too bad for DNA), nicotine
                   (cigarettes), cocaine
            C. Can cause panic, feeling of losing touch with reality, nervous
               system damage, death
                1. Examples: LSD, mushrooms, XTC
      III. Using drugs now can shorten your lifespan.


Summary:
II. All Illegal Drugs Damage DNA

• Why is DNA
  damage bad?
      DRUGS DAMAGE DNA                              Date:

      I. Drugs are substances that change normal bodily function.
      II. All of the following illegal drugs damage DNA (can harm the
           person and/or the offspring)
            A. Can cause unconsciousness, vomiting, brain damage and
               death
                1. Examples: alcohol, heroin, marijuana
            B. Can cause seizures, headaches, paranoia, cancer, and death
                1. Examples: caffeine* (not too bad for DNA), nicotine
                   (cigarettes), cocaine
            C. Can cause panic, feeling of losing touch with reality, nervous
               system damage, death
                1. Examples: LSD, mushrooms, XTC
      III. Using drugs now can shorten your lifespan.


Summary:
Types of Drugs, and What They Do
             to you.
A. Depressants slow you down
• cause unconsciousness, vomiting, brain damage and
  death
      • Examples: alcohol, heroin, marijuana
      DRUGS DAMAGE DNA                               Date:

      I. Drugs are substances that change normal bodily function.
      II. All of the following illegal drugs damage DNA (can harm the
           person and/or the offspring)
            A. Depressants cause unconsciousness, vomiting, brain damage
               and death
                1. Examples: alcohol, heroin, marijuana
            B. Stimulants cause seizures, headaches, paranoia, cancer, and
               death
                1. Examples: caffeine* (not too bad for DNA), nicotine
                   (cigarettes), cocaine
            C. Hallucinogens cause panic, feeling of losing touch with reality,
               nervous system damage, death
                1. Examples: LSD, mushrooms, XTC
      III. Using drugs now can shorten your lifespan.

Summary:
Types of Drugs, and What They Do
             to you.
B. Stimulants speed you up.
• cause seizures, headaches, paranoia, cancer, and
  death
     • Examples: caffeine* (not too bad for DNA),
        nicotine (cigarettes), cocaine
      DRUGS DAMAGE DNA                               Date:

      I. Drugs are substances that change normal bodily function.
      II. All of the following illegal drugs damage DNA (can harm the
           person and/or the offspring)
            A. Depressants cause unconsciousness, vomiting, brain damage
               and death
                1. Examples: alcohol, heroin, marijuana
            B. Stimulants cause seizures, headaches, paranoia, cancer, and
               death
                1. Examples: caffeine* (not too bad for DNA), nicotine
                   (cigarettes), cocaine
            C. Hallucinogens cause panic, feeling of losing touch with reality,
               nervous system damage, death
                1. Examples: LSD, mushrooms, XTC
      III. Using drugs now can shorten your lifespan.

Summary:
Types of Drugs, and What They Do
             to you.
Hallucinogens make you see and feel things that
 aren’t real.
  – cause panic, feeling of losing touch with reality,
    nervous system damage, death
     • Examples: LSD, mushrooms, XTC
      DRUGS DAMAGE DNA                               Date:

      I. Drugs are substances that change normal bodily function.
      II. All of the following illegal drugs damage DNA (can harm the
           person and/or the offspring)
            A. Depressants cause unconsciousness, vomiting, brain damage
               and death
                1. Examples: alcohol, heroin, marijuana
            B. Stimulants cause seizures, headaches, paranoia, cancer, and
               death
                1. Examples: caffeine* (not too bad for DNA), nicotine
                   (cigarettes), cocaine
            C. Hallucinogens cause panic, feeling of losing touch with reality,
               nervous system damage, death
                1. Examples: LSD, mushrooms, XTC
      III. Using drugs now can shorten your lifespan.

Summary:
III. Using drugs NOW can shorten
            your lifespan
      DRUGS DAMAGE DNA                               Date:

      I. Drugs are substances that change normal bodily function.
      II. All of the following illegal drugs damage DNA (can harm the
           person and/or the offspring)
            A. Depressants cause unconsciousness, vomiting, brain damage
               and death
                1. Examples: alcohol, heroin, marijuana
            B. Stimulants cause seizures, headaches, paranoia, cancer, and
               death
                1. Examples: caffeine* (not too bad for DNA), nicotine
                   (cigarettes), cocaine
            C. Hallucinogens cause panic, feeling of losing touch with reality,
               nervous system damage, death
                1. Examples: LSD, mushrooms, XTC
      III. Using drugs now can shorten your lifespan.

Summary:
 GP: Think, Pair, Share

1. Melanie is at a club in the city. A stranger
  offers her some XTC. What scientific
  information could she use to help her make a
  decision about using this drug?
 GP: Think, Pair, Share

2. Abraham is hanging out with some friends. A
  stranger approaches the group and offers
  them all some marijuana. What scientific
  evidence could Abraham tell his friends that
  could help them make this decision?
 GP: Think, Pair, Share

3. Xavier is a miner in Chile. All of his co-workers
  use cocaine so they can stay awake in the
  mine and be less hungry. When he is offered
  cocaine, what scientific evidence could he use
  to help him make his decisions?
  INP:

1. Frederick is hiking in the woods and finds
  some mushrooms. His friend tells him that
  eating these mushrooms will make him
  hallucinate. What scientific information could
  Frederick use to help him make a decision
  about using this drug?
  INP:

2. A person is on a crowded street corner, where
  lots of people are taking a “cigarette break.”
  One of the person’s co-workers offers a
  cigarette to the person. What scientific
  information could the person use to help
  make a decision about using this drug?
                Exit Ticket:
1. Bob sees many adults who use alcohol. He
   wants to make an informed decision about
   using alcohol. What scientific knowledge
   could Bob use to help him make his decision?

2. Elyse is offered tobacco. She wants to make
   an informed decision about using the drug.
   What scientific knowledge could she use to
   help her make the decision?
             11.18.2010 Catalyst:
Monday:        Genes are parts of chromosomes that code
11.15.2010     for inherited traits
               Alleles are different versions of a gene.
Tuesday:       How many alleles for each gene do
11.16.2010     reproductive cells contain? Why?
Wednesday:     Drugs damage DNA. Drugs shorten lifespan.
11.17.2010
Thursday:      Draw a Punnett Square on your
11.18.2010     paper, fill in the table, and answer
               the following question: A purple
               flower (Pp) is crossed with a white
               flower (pp). What percentage of the
               offspring will be white?
         Standards and Objectives
Standard:
II.II.II.6. Know that hereditary information is contained in
    genes that are located in chromosomes, including:
   -determination of traits by genes
   -traits determined by one or many genes
   -more than one trait sometimes influenced by a single gene.

Content:
SWBAT:
Explain that inherited traits can be caused by many genes.
Explain that inherited traits (more than one) can be caused by
  one gene.

Language:
SWBAT make 3 versions of a cause-effect diagram
          Genetics After Gregor Mendel
AGENDA:
                       11.18.2010
             :
            : Eye Color Explanation
       : Notes about Genetics
    : Graphic Cause-Effect
  Organizers
      : ACE Paragraph
               Hand in ACE
  Paragraph
          Cold Call
        Opening: Eye color doesn’t follow
                Mendel’s rules.




http://www.art-dept.com/artists/rankin/portfolio/specialprojects/eyescapes/portfolio.html
Opening: Eye color doesn’t follow
        Mendel’s rules.
Opening: Eye color doesn’t follow
        Mendel’s rules.
Opening: Eye color doesn’t follow
        Mendel’s rules.
Opening: Eye color doesn’t follow
        Mendel’s rules.
Opening: Eye color doesn’t follow
        Mendel’s rules.
Opening: Eye color doesn’t follow
        Mendel’s rules.
Opening: Eye color doesn’t follow
        Mendel’s rules.
 Scientists found that genes do not
always work like Mendel described.
Mendel: One allele = one trait
     Genetics Since G. Mendel                           Date:

     I. Scientists found that genes do not always work like Mendel
        described.
         A. More than one gene can cause one trait
             1. Example: Eye color and height are caused by more
                than one gene.
         B. More than one trait can be caused by one gene
             1. Example: Chicken “Frizzle” disorder,
                Phenylketonuria (PKU)
         C. The environment can play a role in gene expression
             1. Example: Himalayan rabbits have genes that make
                their fur dark only at lower temperatures



Summary:
 A. More than one gene can cause
            one trait.
Eye Color

Human
 Height
     Genetics Since G. Mendel                           Date:

     I. Scientists found that genes do not always work like Mendel
        described.
         A. More than one gene can cause one trait
             1. Example: Eye color and height are caused by more
                than one gene.
         B. More than one trait can be caused by one gene
             1. Example: Chicken “Frizzle” disorder,
                Phenylketonuria (PKU)
         C. The environment can play a role in gene expression
             Note: Leave 6 lines of space
             1. Example: Himalayan rabbits have genes that make
                their fur dark B
             before letteronly at lower temperatures

Summary:
    B. More than one trait can be
        caused by one gene.
• Chicken “Frizzle”
  disorder

• PKU
     Genetics Since G. Mendel                           Date:

     I. Scientists found that genes do not always work like Mendel
        described.
         A. More than one gene can cause one trait
             1. Example: Eye color and height are caused by more
                than one gene.
         B. More than one trait can be caused by one gene
             1. Example: Chicken “Frizzle” disorder,
                Phenylketonuria (PKU)
         C. The environment can play a role in gene expression
             Note: Leave 6 lines of space
             1. Example: Himalayan rabbits have genes that make
                their fur dark C
             before letteronly at lower temperatures

Summary:
     Genetics Since G. Mendel                           Date:

     I. Scientists found that genes do not always work like Mendel
        described.
         A. More than one gene can cause one trait
             1. Example: Eye color and height are caused by more
                than one gene.
         B. More than one trait can be caused by one gene
             1. Example: Chicken “Frizzle” disorder,
                Phenylketonuria (PKU)
         C. The environment can play a role in gene expression
             1. Example: Himalayan rabbits have genes that make
                their fur dark only at lower temperatures



Summary:
        GP: Graphic Organizers
• More than one gene can cause one trait
        GP: Graphic Organizers
More than one trait can be caused by one gene.
         GP: Graphic Organizers
• The environment can play a role in gene
  expression


  Gene
         INP: ACE Paragraph
Explain 3 ways genes and traits don’t
 work like Gregor Mendel suggested
    Genes and traits always don’t work like Gregor
Mendel suggested. First….. An example of this is…..
Second…. An example of this is…. Third…. An
example of this is….
These are three ways that genes and traits don’t work
like Gregor Mendel suggested.
               ACE Exemplar
     Genes and traits don’t always work like Gregor
Mendel suggested. First, scientists have found that one
gene can cause multiple traits. An example of this is the
“frizzle” chicken. Second, scientists have found that
multiple genes can cause one trait. Human height and
eye color are caused by multiple genes. Last, scientists
have found that the environment can affect how genes
are expressed. For example, the Himalayan rabbit has
black fur only on parts of its body that have a lower
temperature. In summary, these are three ways that
genetics is different from Mendel’s theories of simple
inheritance.
                   11.18.2010 Catalyst:
Monday: 11.15.2010    Genes are parts of chromosomes that code for
                      inherited traits
                      Alleles are different versions of a gene.
Tuesday: 11.16.2010 How many alleles for each gene do reproductive cells
                      contain? Why?
Wednesday: 11.17.2010 Drugs damage DNA. Drugs shorten lifespan.
Thursday: 11.18.2010   50% of the offspring will be white

Friday:                Draw the Cause-Effect diagram, and put the
11.19.2010             following words into the blanks [gene 1, gene
                       2, gene 3, trait].
       Standards and Objectives
Standard:
III.I.I.2. Analyze how technologies have been
    responsible for advances in medicine (e.g.,
    vaccines, antibiotics, microscopes, DNA
    technologies)
Content:
SWBAT:
Explain how genetic engineering or gene testing can
    make people healthier

Language:
SWBAT make write a short-answer response (2-3
  complete sentences
                 DNA Technology
AGENDA:
                      11.19.2010
             :
            : What do you think
  genetic engineering is?
       : Notes about DNA Technology
    : Graphic Cause-Effect
  Organizers
      : ACE Paragraph
               Hand in ACE
  Paragraph
          Cold Call
Opening: What do you think of when you
      hear “Genetic Engineering”.
   I. DNA technologies have been
responsible for advances in medicine
             and health
     Genetics Since G. Mendel                                  Date:

     I. DNA technologies have been responsible for advances in
        medicine and health
         A. Genetic Engineering—allows scientists to arrange DNA in
            organisms
             1. Scientists use bacteria to produce insulin.
             2. Some corn can kill pests that feed on it, or to withstand
                cold temperatures
             3. “Golden Rice” has more vitamins than ordinary rice.
         B. Some people oppose genetically modifying organisms
             1. Modified genes may be transferred to other organisms.




Summary:
           Genetic Engineering:
• Scientists arrange DNA in organisms.
         Genetics Since G. Mendel                                  Date:

         I. DNA technologies have been responsible for advances in
            medicine and health
             A. Genetic Engineering—allows scientists to arrange DNA in
                organisms
                 1. Scientists use bacteria to produce insulin.
Write            2. Some corn can kill pests that feed on it, or to withstand
    of              cold temperatures
these
                 3. “Golden Rice” has more vitamins than ordinary rice.
down
             B. Some people oppose genetically modifying organisms
                 1. Modified genes may be transferred to other organisms.




 Summary:
Why are people against Genetic
        Engineering?

            • Modified genes could be
              spread to other
              organisms

            • Other ideas?
     Genetics Since G. Mendel                                  Date:

     I. DNA technologies have been responsible for advances in
        medicine and health
         A. Genetic Engineering—allows scientists to arrange DNA in
            organisms
             1. Scientists use bacteria to produce insulin.
             2. Some corn can kill pests that feed on it, or to withstand
                cold temperatures
             3. “Golden Rice” has more vitamins than ordinary rice.
         B. Some people oppose genetically modifying organisms
             1. Modified genes may be transferred to other organisms.




Summary:
Genetic Testing
            • Scientists can
              test genes and
              determine if
              babies will
              have a disease
     Genetics Since G. Mendel                                  Date:

     I. DNA technologies have been responsible for advances in
        medicine and health
         A. Genetic Engineering—allows scientists to arrange DNA in
            organisms
             1. Scientists use bacteria to produce insulin.
             2. Some corn can kill pests that feed on it, or to withstand
                cold temperatures
             3. “Golden Rice” has more vitamins than ordinary rice.
         B. Some people oppose genetically modifying organisms
             1. Modified genes may be transferred to other organisms.
         C. Genetic Testing allows scientists to predict whether or not a
            baby will have a disease.



Summary:
GP: What are the good and bad
 parts to genetic engineering?
    INP/Exit Ticket: Write these
    answers on a sheet of paper
How can genetic engineering make people
 healthier?

Why do you think people are opposed to genetic
 engineering?

				
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