Skin Cells Converted
To Beating Heart Cells
Without Stem Cell
By Abraham Angulo
Professor Sheng Ding
On Sunday January 31, 2011
The process of converting skin cells to beating heart cells by skipping the stem cell
stage was first realized successfully on Sunday January 31, 2011. The research was
realized by Professor Sheng Ding who was leading this study and research. This research
will advance the medical world greatly in many ways and help avoid some obstacles posed
by stem cells. Converting skins cells directly to beating heart cells is a process that was
first inspired by stem cells and basically it is the same outcome just a different procedure
from the same idea of developing pluripotent stem cells. Converting skin cells directly to
the cells where the body needs them has many medical applications, and could lead to
treating cells injured or destroyed by disease and damage, Parkinson’s, Alzheimers, and
heart disease. If this procedure is approved it can remove some dangers with stem cells
such as the possibility to develop a tumor.
The advantage of this procedure is that the cells put back into your body are your
own just like pluripotent stem cells. Meaning your body will accept the converted stem cells
without any drugs or medical treatment to force your body to accept the converted cells.
The difference between this procedure and pluripotent stem cells are that converting skin
cells skips the stem cell stage and goes directly to the completed form of what cell is
needed. The main advantage of this procedure is that converting the cells skips all the
maintaining of the pluripotent stem cells and it is faster to convert the skin cells to the cells
required. This procedure is not better than changing skin cells to pluripotent stem cells
because it is the same procedure just enhanced. The way the procedure is done is by
taking the same original four genes and injecting the into the skin cell just like in the
pluripotent stem cells procedure. The difference is that in the pluripotent procedure the
genes are left active in the cell for weeks, but in the converting procedure the genes are
left inactive just after a couple of days way before the cells can turn into iPS cells. After
genes are turned off the scientist send a signal to the cells to turn into heart cells. Although
this procedure has made a major breakthrough it is still very recent and further studies are
required to see if the conversion can be done for other needs in cells besides heart
necessities. If accomplished going through the pluripotent procedure will become obsolete.
Converting skin cells
This process is converting an adult cell to
a completely new cell without the stem
The process begins with and adult skin
cell and injecting the four original genes
from the iPS process.
After inserting the four genes the scientist
turn off the genes to be inactive just after a
couple of days after being inserted.
Then a signal is given to the cell to turn
into the cell which is needed.
This process is like making iPS cells, but
without the long laborious process.
Pluripotent Stem Cell
This process eliminates the long
laborious process of converting skin cells
to iPS cells.
Don’t have to maintain the iPS cells.
Directly treat illness.
This procedure hasn’t been developed
Can only been done to beating heart
Could lead to treating cells injured or
destroyed by disease and damage,
Parkinson’s, Alzheimers, and heart
When studies keep advancing this
procedure can be used to treat any
damage to the body.
THE FUTURE NOW
Replace iPS cells.
There is no need to create iPS cells if
you can get the cells needed right away.