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					Table S2. Identification of distant homologs of S-TIM5 ORFs using:
A) HHpred analysis
ORF No.    Predicted function                           PfamA ID      E-value
21         Adenine DNA methyltransferae                 PF02086       2.60E-25
26         Glycosyl transferase                         PF00535       3.80E-15
30         Outer membrane protein                       PF01389       3.30E-17
44         Antitoxin                                    PF02604       1.30E-17
81         Major capsid protein                         PF03864       2.60E-16
83         Capsid scaffolding protein                   PF05929       8.40E-26
84         Tail sheath protein                          PF04984       5.90E-37
127        Thioredoxin                                  PF00085       1.20E-15
132        Pentaxin                                     PF00354       1.70E-17
           Sialidase                                    PF02973       6.40E-15
163        Baseplate wedge protein                      PF04965       2.10E-21




B) PSI-Blast analysis
ORF No.    Predicted function             Phage with best E-value   E-value
81         Major capsid protein           BceMu, phiE255, B3        E-88, E-84, E-83
84         Tail sheath protein            JSE, JS98, RB49           0, 0, 0
134        Baseplate wedge subunit        RB49                      6.14 E-49
162        Tail assembly protein          D108                      1.50 E-50

				
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