The diagnosis and treatment of malignant mesothelioma by anamaulida


									Malignant pleural mesothelioma(MPM), originated from pleural mesothelium
cell, is an fatal tumor with natual history of only about several months,
has showed an increased morbidity recently. The cause is that work or
live in asbestos environment, and then Asbestos or dust is inhaled chest.
Symptoms of malignant mesothelioma are similar with lung disease,
However, it is difficult to diagnose pleural mesothelioma in its early
stages because its symptoms often mimic the symptoms of other common
illnesses, such as the flu, pneumonia or laryngitis. The best treatment
time to be missed. Mesothelioma CT image is considered the best method of
diagnosis. Comparing results from imaging scans tissue biopsies pulmonary
function tests and other diagnostic techniques the presence of
mesothelioma can be identified.      Mesothelioma is a rare disorder,
affecting about three thousand people per year, while lung cancer has a
diagnostic rate 65 times greater than mesothelioma with nearly 200, 000
yearly diagnoses. Malignant mesothelioma is a mesothelium-derived
carcinoma with high malignancy. The treatment of malignant pleural
mesothelioma, is still no effective cure methods. Pemetrexed disodium is
the only agent for the treatment of malignant pleural mesothelioma(MPM).
It is a multitargeted antimetabolite that has shown activity in malignant
pleural mesothelioma and NSCLC, which has been approved in more than 70
countries. The use of pemetrexed for lung cancer was also high in France
and the United States and low in Canada, the Czech Republic, New Zealand,
Poland, and the United Kingdom. pemetrexed is an anticancer drug,
Pemetrexed and cis-platinum are combined for the treatment of Malignant
mesothelioma. This drug is used by intravenous drop infusion. The
recommended dose is 500mg/m2 every 21 days. Pemetrexed is injected
droplet Into the human body. Time must be more than 10 minutes. Cisplatin
dose is 75mg/m2, infusion time must be more than 2 hours. Cisplatin began
to be injected after 30 minutes pemetrexed has been injected. if the
patients accepted cisplatin, need to make a hydration program.

  cisplatin is an anticancer drug. cisplatin was discovered in 1964 by a
biophysicist when he did an experiment to study the effect of electric
field on growth of bacteria (using platinum electrodes). The main
mechanism of cisplatin is tumor cells death by damaging the DNA. The
resistance to cisplatin is associated with the cell's increased ability
of DNA repair. Pemetrexed and cisplatin was combined for the treatment of
inoperable malignant pleural mesothelioma.      The diagnosis and
treatment of malignant mesothelioma. Curative
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