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					Survey Results & analysis for

   ATS Assembly on Respiratory
    Structure & Function Project
         Proposal Initiative
Executive Summary
This report contains a detailed statistical analysis of the results to the survey titled ATS Assembly on Respiratory
Structure & Function Project Proposal Initiative . The results analysis includes answers from all respondents who took
the survey in the 70 day period from Tuesday, May 12, 2009 to Monday, July 20, 2009. 71 completed responses were
received to the survey during this time.


Survey Results & Analysis
Survey: ATS Assembly on Respiratory Structure & Function Project Proposal Initiative
Author:
Filter:
Responses Received: 71
Provide up to three suggestions for existing or new areas of significant
importance or controversy that you feel should be considered for project
development:
                   1                                       2                                        3

Ventilation/Persusion in artificial   Effects of air pollution (physical,
ventilation - heterogeneity of        chemical, biological) on
perfusion as a cause of               airway/parenchyma structure and
hypoventilation: a forgotten issue    remodeling


Exhaled breath analysis for desese    Innovations in technology that may have Update on Methacholine challenge testing
diagnosis.                            utlity in the meidical field.

Transcriptional mechanisms of         Altered surfactant metabolism in         lung morphogenesis
recovery from acute lung injury       diseased lung

Respiratory Health Effects of Climate The mechanisms and role of airway
Change                                nerves in airway diseases.

Exhaled breath analysis for disease Innovations in technology that will have   Update on Methacholine challenge testing
diagnosis.                          future utility in the medical field.

lung repair in COPD
Severe asthma: pathogenesis and       Airway Smooth Muscle Cells anf
new treatments                        Myofibroblasts as targets for treating
                                      asthma and COPD
Phenotyping of animal models of          Quantitative lung imaging                      Alveolar cell and tissue mechanics
emphysema

pulmonary vasculopathy in metabolic pulmonary vascular response to                      cytoskeletal microdomains in endothelial repair
disease:acute vs chronic            inflammatory damage: regio-temporal
inflammatory response               specific "hot spots"

Functional consequences of airway
smooth muscle remodeling



Origins of increased smooth muscle       Clinical trial of inhaled corticosteroids on   Airway smooth muscle hypertrophy or
in asthma.                               airway smooth muscle hyperplasia.              hyperplasia in COPD.



The significance of the small airways
in asthma: measurement, phenotypes
& treatment.



Complex behavior of the respiratory
system in health and disease



Cyclical recruitment of atelectasis as
a mechanism of ventilator-associated
lung injury

exhaled breath analysis
oral-cavity interferences with
measurements of exhaled trace
constituents from airways

Role of extracellular matrix in airway
hyperesponsiveness

Airway epithelial barrier function in    Airway epithelial models of health and
health and disease                       disease

Airway Acid and Oxidative Stress--
Biochemical Impacts on Airway
Function

complex in vitro models:
epithelial/endothelial,
Epithelial/smooth muscle,
Epithelial/leukocyte

Interaction of nanoparticles with        Electron tomography - 3D electron          Nanoparticulate matter in pulmonary medicinal
biological systems and subsequent        microscopy: interaction of nanoparticles   application; diagnistics, therapeutics
effects - interaction with the lung,     with subcellular structures like           (nanomedicine)
lung tissue and lung cells               cytoskeleton, organelles, the nucleus



miRNA in lung function and airway
remodeling

Dynamics of oxygen delivery              Gas equation and it's clinical relation    Atelectasis and it's management in context of
                                                                                    mechanical ventilation

COPD rehabilitation                      screening upper mechanics for OSA          neuromuscular/chest wall disorders
severe asthma phenotypes              animal models for rare pulmonary          therapeutic targets in chronic cough
                                      diseases
MODULATION OF SMALL AIRWAY INFLUENCE OF VARIOUS BREATHING VARIABILITY IN ACUTE LUNG INJURY DUE
INFLAMMATION IN ASTHMA WITH MANOUVERS ON AIRWAY CALIBRE   TO DIFFERENT ETIOLOGICAL FACTORS ,
EXISTING & NEWER INHALERS   INCLUDING YOGIC BREATHING     SEPSIS IN PARTICULAR
                            WHICH HAS IMMENSE POTENTIAL
                            WHICH HAS NOT BEEN ADDRESSED
                            YET.


Cardiopulmonary exercise capacity in Obesity and respiratory function at rest
obesity. Typical reporting may mask and during exercise. Also, dyspnea on
the fact that many obese are not     exertion.
deconditioned but rather
symptomatic. A position document
would be very helpful in the area.



Tracheostomies in children -
standards of care for ongoing
management, bronchoscopy etc
Dyspnea - more than altered
mechanics
Obesity                               Respiratory Muscles
lung development in the extremely
premature neonate, ventilation
strategies for these patients


In vitro modelling of healthy airways In vitro respiratory drug delivery and
                                      testing
endothelial dysfuction in ARDS         endothelial pathophysiology in               pulmonary circulation in ventilator injury
                                       pulmonary hypertension
ATS Methacholine Challange             Pulmonary Physiology in the 21st             Exhaled Breath measurement for Disease.
Guideline Update. last was is 1999     century Innovations in testing and           We had previouslt published a paper on
                                       design.                                      detecting Lung cancer. Now we are looking at
                                                                                    all disease. This I would like to chair as I have
                                                                                    the background and expertise.


Lung residenet stem cells              inducible prluripotent stem cells            microparticles
Animal models of emphysema             Innate immune function in COPD
Interaction of inflammatory and         The role of programmed cellular death in
alveolar epithelial cells in acute lung response to stress in resident lung cells
injury
stem cell research                     effect of nanoparticles in health and
                                       disease
Pulmonary nontuberculous
mycobacterial disease
x-dr tuberculosis                      ARDS                                         MULTIRESISTANT ORGANISMS IN VAP

Steroid resistance in structural cells Glucocorticoid signaling                     Alternative therapy in Severe asthma

New metabolic or lipid pathways that Statins and airway disease.
could modulate airway remodeling.


Air pollution and lung (dys)function   Lung parenchymal structural                  Better understanting FOT and IOS data
                                       components: how do they modify
                                       function
The controversial role of RAGE in Mechanisms of alveolar protein
lung pathophysiology. Queisser MA clearance in the intact lung Am J Physiol
et al.,Am J Respir Cell Mol Biol.    Lung Cell Mol Physiol. 2004
2008 Sep;39(3):337-45 Reynolds       Apr;286(4):L679-89. Review
PR et al.,Am J Respir Cell Mol Biol.
2009 Jun 25 Sternberg DI et al., J
Thorac Cardiovasc Surg. 2008
Dec;136(6):1576-85 Englert JM et
al., Am J Pathol. 2008
Mar;172(3):583-91 He M et al., Am J
Physiol Lung Cell Mol Physiol. 2007
Dec;293(6):L1427-36.



The development of airway smooth The composition of the ectracellular
muscle in utero and early life.  matrix in asthma.
Factors influencing cell number.

Role of imaging in lung disease    Translation of new technologies to         Standards for performance for diagnostic and
                                   clinical practice                          monitoring tools in critical care
Airway wall remodelling            Signal transduction cascades underlying Airway hyperresponsiveness; mechanisms
                                   development and severity of airway      and consequences
                                   diseases
Airway smooth muscle as a major Statistical mechanics: a new way to
actor in airway                   establish a link between microscopic
hyperresponsiveness: from whole properties of airway smooth muscle and
muscle mechanics to the assesment its bulk mechanical properties.
of crossbridge properties.


Murine and other animal models of Modeling airway hyperresponsiveness         Aging and the lung
COPD
1. (Provide up to three suggestions for existing or new areas of
significant importance or controversy that you feel should be
considered for project development:)
1.
Ventilation/Persusion in artificial ventilation - heterogeneity of perfusion as a cause of hypoventilation: a forgotten issue
Exhaled breath analysis for desese diagnosis.
Transcriptional mechanisms of recovery from acute lung injury
Respiratory Health Effects of Climate Change
Exhaled breath analysis for disease diagnosis.
lung repair in COPD
Severe asthma: pathogenesis and new treatments
Phenotyping of animal models of emphysema
pulmonary vasculopathy in metabolic disease:acute vs chronic inflammatory response
Functional consequences of airway smooth muscle remodeling
Origins of increased smooth muscle in asthma.
The significance of the small airways in asthma: measurement, phenotypes & treatment.
Complex behavior of the respiratory system in health and disease
Cyclical recruitment of atelectasis as a mechanism of ventilator-associated lung injury
exhaled breath analysis
oral-cavity interferences with measurements of exhaled trace constituents from airways
Role of extracellular matrix in airway hyperesponsiveness
Airway epithelial barrier function in health and disease
Airway Acid and Oxidative Stress--Biochemical Impacts on Airway Function
complex in vitro models: epithelial/endothelial, Epithelial/smooth muscle, Epithelial/leukocyte
Interaction of nanoparticles with biological systems and subsequent effects - interaction with the lung, lung tissue and lung cells
miRNA in lung function and airway remodeling
Dynamics of oxygen delivery
COPD rehabilitation
severe asthma phenotypes
MODULATION OF SMALL AIRWAY INFLAMMATION IN ASTHMA WITH EXISTING & NEWER INHALERS

Cardiopulmonary exercise capacity in obesity. Typical reporting may mask the fact that many obese are not deconditioned but
rather symptomatic. A position document would be very helpful in the area.
Tracheostomies in children - standards of care for ongoing management, bronchoscopy etc
Dyspnea - more than altered mechanics
Obesity
lung development in the extremely premature neonate, ventilation strategies for these patients
In vitro modelling of healthy airways
endothelial dysfuction in ARDS
ATS Methacholine Challange Guideline Update. last was is 1999
Lung residenet stem cells
Animal models of emphysema
Interaction of inflammatory and alveolar epithelial cells in acute lung injury
stem cell research
Pulmonary nontuberculous mycobacterial disease
x-dr tuberculosis
Steroid resistance in structural cells
New metabolic or lipid pathways that could modulate airway remodeling.
Air pollution and lung (dys)function
The controversial role of RAGE in lung pathophysiology. Queisser MA et al.,Am J Respir Cell Mol Biol. 2008 Sep;39(3):337-45
Reynolds PR et al.,Am J Respir Cell Mol Biol. 2009 Jun 25 Sternberg DI et al., J Thorac Cardiovasc Surg. 2008
Dec;136(6):1576-85 Englert JM et al., Am J Pathol. 2008 Mar;172(3):583-91 He M et al., Am J Physiol Lung Cell Mol Physiol.
2007 Dec;293(6):L1427-36.
The development of airway smooth muscle in utero and early life. Factors influencing cell number.
Role of imaging in lung disease
Airway wall remodelling
Airway smooth muscle as a major actor in airway hyperresponsiveness: from whole muscle mechanics to the assesment of
crossbridge properties.
Murine and other animal models of COPD
2.
Effects of air pollution (physical, chemical, biological) on airway/parenchyma structure and remodeling
Innovations in technology that may have utlity in the meidical field.
Altered surfactant metabolism in diseased lung
The mechanisms and role of airway nerves in airway diseases.
Innovations in technology that will have future utility in the medical field.
Airway Smooth Muscle Cells anf Myofibroblasts as targets for treating asthma and COPD
Quantitative lung imaging
pulmonary vascular response to inflammatory damage: regio-temporal specific "hot spots"
Clinical trial of inhaled corticosteroids on airway smooth muscle hyperplasia.
Airway epithelial models of health and disease
Electron tomography - 3D electron microscopy: interaction of nanoparticles with subcellular structures like cytoskeleton, organelles, the
nucleus
Gas equation and it's clinical relation
screening upper mechanics for OSA
animal models for rare pulmonary diseases
INFLUENCE OF VARIOUS BREATHING MANOUVERS ON AIRWAY CALIBRE INCLUDING YOGIC BREATHING WHICH HAS
IMMENSE POTENTIAL WHICH HAS NOT BEEN ADDRESSED YET.
Obesity and respiratory function at rest and during exercise. Also, dyspnea on exertion.
Respiratory Muscles
In vitro respiratory drug delivery and testing
endothelial pathophysiology in pulmonary hypertension
Pulmonary Physiology in the 21st century Innovations in testing and design.
inducible prluripotent stem cells
Innate immune function in COPD
The role of programmed cellular death in response to stress in resident lung cells
effect of nanoparticles in health and disease
ARDS
Glucocorticoid signaling
Statins and airway disease.
Lung parenchymal structural components: how do they modify function
Mechanisms of alveolar protein clearance in the intact lung Am J Physiol Lung Cell Mol Physiol. 2004
Apr;286(4):L679-89. Review
The composition of the ectracellular matrix in asthma.
Translation of new technologies to clinical practice
Signal transduction cascades underlying development and severity of airway diseases
Statistical mechanics: a new way to establish a link between microscopic properties of airway smooth muscle and
its bulk mechanical properties.
Modeling airway hyperresponsiveness
3. (Provide up to three suggestions for existing or new areas of significant importance or controversy that you feel should be
considered for project development:)
 3.
 Update on Methacholine challenge testing
 lung morphogenesis
 Update on Methacholine challenge testing
 Alveolar cell and tissue mechanics
 cytoskeletal microdomains in endothelial repair
 Airway smooth muscle hypertrophy or hyperplasia in COPD.
 Nanoparticulate matter in pulmonary medicinal application; diagnistics, therapeutics (nanomedicine)
 Atelectasis and it's management in context of mechanical ventilation
 neuromuscular/chest wall disorders
 therapeutic targets in chronic cough
 VARIABILITY IN ACUTE LUNG INJURY DUE TO DIFFERENT ETIOLOGICAL FACTORS , SEPSIS IN
 PARTICULAR
 pulmonary circulation in ventilator injury
 Exhaled Breath measurement for Disease. We had previouslt published a paper on detecting Lung cancer. Now we
 are looking at all disease. This I would like to chair as I have the background and expertise.
 microparticles
 MULTIRESISTANT ORGANISMS IN VAP
 Alternative therapy in Severe asthma
 Better understanting FOT and IOS data
 Standards for performance for diagnostic and monitoring tools in critical care
 Airway hyperresponsiveness; mechanisms and consequences
 Aging and the lung
Acute Lung Injury
                        Most Desirable   Desirable    Somewhat     Not Desirable   Least Desirable
                                                      Desirable
Cytoskeletal            25.4% (16)       30.2% (19)   28.6% (18)   7.9% (5)        7.9% (5)
dynamics in lung
health and disease
Immune response         14.3% (9)        38.1% (24)   23.8% (15)   15.9% (10)      7.9% (5)
in ventilator-injured
lungs
Advances in             15.9% (10)       17.5% (11)   42.9% (27)   14.3% (9)       9.5% (6)
ventilator
technology and
modalities
Osmotic stress and      6.3% (4)         28.6% (18)   39.7% (25)   14.3% (9)       11.1% (7)
lung injury & repair
Cytoskeletal dynamics in lung health and disease(Acute Lung Injury)
Immune response in ventilator-injured lungs(Acute Lung Injury)
Advances in ventilator technology and modalities(Acute Lung Injury)
Osmotic stress and lung injury & repair(Acute Lung Injury)
Lung (Patho)Physiology and Mechanics
                        Most Desirable   Desirable    Somewhat     Not Desirable   Least Desirable
                                                      Desirable
Murine models of        16.7% (11)       40.9% (27)   25.8% (17)   9.1% (6)        7.6% (5)
asthma– strengths,
weaknesses,
opportunities and
threats
Neural control of the   15.4% (10)       29.2% (19)   40.0% (26)   13.8% (9)       1.5% (1)
airways
Modulation of the       13.8% (9)        24.6% (16)   36.9% (24)   16.9% (11)      7.7% (5)
cough reflex
TRP channels in         8.1% (5)         19.4% (12)   43.5% (27)   24.2% (15)      4.8% (3)
airway pathobiology
Quantifying             34.8% (23)       19.7% (13)   33.3% (22)   10.6% (7)       1.5% (1)
emphysema in
humans and mice
Neuropeptide            8.3% (5)         30.0% (18)   43.3% (26)   15.0% (9)       3.3% (2)
modulation airway
mechanics in
asthma
Influence of the        23.4% (15)       46.9% (30)   20.3% (13)   6.3% (4)        3.1% (2)
epithelium on
airway calibre
Small airway            35.4% (23)       47.7% (31)   12.3% (8)    4.6% (3)        0.0% (0)
function:
inflammation,
airway calibre and
heterogeneity
Airway                  36.9% (24)       35.4% (23)   20.0% (13)   6.2% (4)        1.5% (1)
hyperresponsivenes
s: molecules to man
Role of lung            15.9% (10)       38.1% (24)   30.2% (19)   11.1% (7)       4.8% (3)
surfactant in
modulating airway
mechanics in
asthma
Gender differences      13.4% (9)    34.3% (23)   31.3% (21)   16.4% (11)   4.5% (3)
in health, aging and
lung disease

Vascular barrier        8.1% (5)     25.8% (16)   43.5% (27)   14.5% (9)    8.1% (5)
properties

Interstitial matrix     18.3% (11)   40.0% (24)   25.0% (15)   10.0% (6)    6.7% (4)
molecules and
tissue mechanics

Use of the forced       7.7% (5)     24.6% (16)   32.3% (21)   20.0% (13)   15.4% (10)
oscillation technique

Severe asthma –         41.5% (27)   27.7% (18)   18.5% (12)   9.2% (6)     3.1% (2)
causes,
consequences and
treatment

Pathobiology of rare    12.3% (8)    18.5% (12)   33.8% (22)   23.1% (15)   12.3% (8)
lung diseases

Aging of the            28.6% (20)   41.4% (29)   18.6% (13)   8.6% (6)     2.9% (2)
pulmonary system
Murine models of asthma– strengths, weaknesses, opportunities and threats(Lung (Patho)Physiology and Mechanics)
Neural control of the airways(Lung (Patho)Physiology and Mechanics)
Modulation of the cough reflex(Lung (Patho)Physiology and Mechanics)
TRP channels in airway pathobiology(Lung (Patho)Physiology and Mechanics)
Quantifying emphysema in humans and mice(Lung (Patho)Physiology and Mechanics)
Neuropeptide modulation airway mechanics in asthma(Lung (Patho)Physiology and Mechanics)
Influence of the epithelium on airway calibre(Lung (Patho)Physiology and Mechanics)
Small airway function: inflammation, airway calibre and heterogeneity(Lung (Patho)Physiology and Mechanics)
Airway hyperresponsiveness: molecules to man(Lung (Patho)Physiology and Mechanics)
Role of lung surfactant in modulating airway mechanics in asthma(Lung (Patho)Physiology and Mechanics)
Gender differences in health, aging and lung disease(Lung (Patho)Physiology and Mechanics)
Vascular barrier properties(Lung (Patho)Physiology and Mechanics)
Interstitial matrix molecules and tissue mechanics(Lung (Patho)Physiology and Mechanics)
Use of the forced oscillation technique(Lung (Patho)Physiology and Mechanics)
Severe asthma – causes, consequences and treatment(Lung (Patho)Physiology and Mechanics)
Pathobiology of rare lung diseases(Lung (Patho)Physiology and Mechanics)
Aging of the pulmonary system(Lung (Patho)Physiology and Mechanics)
Airway Smooth Muscle & Airway Remodeling
                        Most Desirable   Desirable    Somewhat     Not Desirable   Least Desirable
                                                      Desirable
Developing in vivo      35.9% (23)       35.9% (23)   18.8% (12)   6.3% (4)        3.1% (2)
methods for
measuring airway
remodeling
Epithelial-             22.2% (14)       31.7% (20)   33.3% (21)   11.1% (7)       1.6% (1)
mesenchymal
transition in airway
and lung
remodeling
Vascular                31.7% (20)       28.6% (18)   27.0% (17)   11.1% (7)       1.6% (1)
remodeling in
pulmonary
hypertension,
asthma and COPD
Airway smooth           31.7% (20)       39.7% (25)   14.3% (9)    12.7% (8)       1.6% (1)
muscle remodeling
and dysfunction in
asthma and COPD
Targeting airway        29.7% (19)       37.5% (24)   20.3% (13)   10.9% (7)       1.6% (1)
remodeling in
asthma treatment
Apoptosis and           20.6% (13)       31.7% (20)   27.0% (17)   19.0% (12)      1.6% (1)
fibrotic lung disease
Association             31.3% (20)       25.0% (16)   29.7% (19)   7.8% (5)        6.3% (4)
between asthma
phenotype and
airway remodeling
Developing in vivo methods for measuring airway remodeling(Airway Smooth Muscle & Airway Remodeling)
Epithelial-mesenchymal transition in airway and lung remodeling(Airway Smooth Muscle & Airway Remodeling)
Vascular remodeling in pulmonary hypertension, asthma and COPD(Airway Smooth Muscle & Airway Remodeling)
Airway smooth muscle remodeling and dysfunction in asthma and COPD(Airway Smooth Muscle & Airway Remodeling)
Targeting airway remodeling in asthma treatment(Airway Smooth Muscle & Airway Remodeling)
Apoptosis and fibrotic lung disease(Airway Smooth Muscle & Airway Remodeling)
Association between asthma phenotype and airway remodeling(Airway Smooth Muscle & Airway Remodeling)
Integrating Structure and Function: Imaging and Modeling
                       Most Desirable   Desirable    Somewhat     Not Desirable   Least Desirable
                                                     Desirable
Lung imaging:          33.3% (21)       44.4% (28)   12.7% (8)    4.8% (3)        4.8% (3)
integrating lung and
cell mechanics
Mathematical           11.1% (7)        27.0% (17)   38.1% (24)   15.9% (10)      7.9% (5)
modeling of lung
disease
Imaging: novel         20.3% (13)       46.9% (30)   21.9% (14)   7.8% (5)        3.1% (2)
techniques
Imaging: early         35.9% (23)       28.1% (18)   20.3% (13)   14.1% (9)       1.6% (1)
detection of disease
Imaging:               38.1% (24)       33.3% (21)   19.0% (12)   7.9% (5)        1.6% (1)
physiological
mechanisms in
health and disease
Ventilation            23.4% (15)       23.4% (15)   32.8% (21)   17.2% (11)      3.1% (2)
heterogeneity:
theoretical modeling
to imaging
Nanotechnology in      25.0% (16)       31.3% (20)   23.4% (15)   14.1% (9)       6.3% (4)
detecting and
treating lung
disease
Lung imaging: integrating lung and cell mechanics(Integrating Structure and Function: Imaging and Modeling)
Mathematical modeling of lung disease(Integrating Structure and Function: Imaging and Modeling)
Imaging: novel techniques(Integrating Structure and Function: Imaging and Modeling)
Imaging: early detection of disease(Integrating Structure and Function: Imaging and Modeling)
Imaging: physiological mechanisms in health and disease(Integrating Structure and Function: Imaging and Modeling)
Ventilation heterogeneity: theoretical modeling to imaging(Integrating Structure and Function: Imaging and Modeling)
Nanotechnology in detecting and treating lung disease(Integrating Structure and Function: Imaging and Modeling)
Respiratory and Peripheral Muscle Biology/Physiology
                      Most Desirable   Desirable    Somewhat     Not Desirable   Least Desirable
                                                    Desirable
Cell and molecular    19.4% (12)       32.3% (20)   33.9% (21)   12.9% (8)       1.6% (1)
mechanisms for
respiratory and
peripheral muscle
failure
Respiratory and       18.0% (11)       27.9% (17)   19.7% (12)   24.6% (15)      9.8% (6)
peripheral muscle
dysfunction in
sepsis
Skeletal muscle       17.5% (11)       34.9% (22)   27.0% (17)   14.3% (9)       6.3% (4)
weakness in COPD
Respiratory muscle    6.5% (4)         38.7% (24)   22.6% (14)   21.0% (13)      11.3% (7)
failure in muscular
dystrophy
Acquired weakness     12.7% (8)        34.9% (22)   25.4% (16)   15.9% (10)      11.1% (7)
syndromes in
critical illness
Mechanical            11.3% (7)        32.3% (20)   27.4% (17)   22.6% (14)      6.5% (4)
ventilation induced
diaphragm
dysfunction
Mechanisms for        23.1% (15)       27.7% (18)   27.7% (18)   13.8% (9)       7.7% (5)
exercise endurance
in asthma and
COPD
Exercise              21.5% (14)       24.6% (16)   29.2% (19)   13.8% (9)       10.8% (7)
rehabilitation
programs for COPD
Cell and molecular mechanisms for respiratory and peripheral muscle failure(Respiratory and Peripheral Muscle
Biology/Physiology)
Respiratory and peripheral muscle dysfunction in sepsis(Respiratory and Peripheral Muscle Biology/Physiology)
Skeletal muscle weakness in COPD(Respiratory and Peripheral Muscle Biology/Physiology)
Respiratory muscle failure in muscular dystrophy(Respiratory and Peripheral Muscle Biology/Physiology)
Acquired weakness syndromes in critical illness(Respiratory and Peripheral Muscle Biology/Physiology)
Mechanical ventilation induced diaphragm dysfunction(Respiratory and Peripheral Muscle Biology/Physiology)
Mechanisms for exercise endurance in asthma and COPD(Respiratory and Peripheral Muscle Biology/Physiology)
Exercise rehabilitation programs for COPD(Respiratory and Peripheral Muscle Biology/Physiology)
Other:
                        Most Desirable   Desirable    Somewhat     Not Desirable   Least Desirable
                                                      Desirable
Hypertonic saline       11.1% (7)        12.7% (8)    46.0% (29)   23.8% (15)      6.3% (4)
inhalation for cystic
fibrosis
Genetics of COPD        21.9% (14)       34.4% (22)   25.0% (16)   10.9% (7)       7.8% (5)
Hypertonic saline inhalation for cystic fibrosis(Other:)
Genetics of COPD(Other:)

				
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