Docstoc

BillCASC2003.ppt - Coalition for Academic Scientific Computation

Document Sample
BillCASC2003.ppt - Coalition for Academic Scientific Computation Powered By Docstoc
					                               National Institute
                               of Biomedical
                               Imaging and
                               Bioengineering
                               William Heetderks, MD, PhD
                               Associate Director for Scientific
                               Programs


                               Coalition for Academic
                               Scientific Computation
                               Spring Meeting
                               March 4, 2003
Department of Health & Human Services, National Institutes of Health
              Overview
• History and Mission of the NIBIB
• NIBIB Portfolio in Bioinformatics and
  Computational Biology
• Trans-NIH Funding Opportunities
• Current NIBIB Funding Opportunities
• Future Directions
Broad Mission of the NIBIB

Improve health by supporting and conducting
focused and multi-disciplinary research and
research training in biomedical imaging and
bioengineering. This includes supporting the
development and translation of emerging
technologies that enable fundamental
discoveries and facilitate disease detection,
management and prevention.
            NIBIB History

• Mandated by H.R. 1795 (PL 106-580)
  – signed by President Clinton on December
   29, 2000
• Result of combined efforts by the
  biomedical imaging and bioengineering
  communities
• Currently staff of 40
• ~600 funded grants / $280 M for FY03
• Poised for growth
          NIBIB Milestones
• Establishment package approved by DHHS in April
  2001 – Dr. Donna Dean named AD
• First budget approved on January 10, 2002
• First RFA’s issued – February 2002
• First grant made – April 2002
• First Director – September 2002
• Futures Workshop – December 2002
• First Advisory Council Meeting (NACBIB) –
  January 2003
• FY03 budget approved – February 20, 2003
• First presentation to CASC – March 4, 2003
  Roderic I. Pettigrew Named
First NIBIB Director – May 7, 2002
NIBIB Portfolio: Bioinformatics &
       Computational Modeling


   •   Imaging Informatics
   •   Human Computer Interface
   •   Image Processing
   •   Data Mining
   •   Computational Modeling
       Imaging Informatics
• Informatics framework for
  standardization of image processing
• Transfer of radiological images and
  reports
• Digital atlases
• Phantom for imaging device validation
• Analysis and display of imaging signals
  Human Computer Interface
• Simulations for clinical training
• Computational tools for remote-
  monitoring and image quantification
• Virtual environment for manipulation of
  molecular models
• Image perception and pattern
  recognition for computer-aided
  diagnosis
        Image Processing
• Image segmentation
• Image registration methods
• Algorithms for manipulating high-
  resolution image volumes
             Data Mining
• Techniques for statistical classification
  and decision-making for cell sorting
    Computational Modeling
• Structural and functional modeling of
  biological processes
• Computational and experimental
  frameworks for real-time mapping of
  biological processes
           Trans-NIH Bioinformatics
            Research Opportunities
• NIH Biomedical Science and Technology
  Initiative (BISTI)
• Established – April 2000
• Consists of representatives of all NIH institutes,
  centers, and office
• Goal is to to promote and coordinate
  bioinformatics research across the NIH
• Administered by the NIGMS
• Chair – Jim Cassatt (NIGMS)
• www.bisti.nih.gov
       BISTIC Programs (1)
•   Continued Development and Maintenance
    of Bioinformatics and Computational Biology
    Software
      PA-02-141 - Released July 26, 2002
     Receipt Dates: February 1, June 1, and October 1


•   Planning Grants: National Programs of
    Excellence in Biomedical Computing (Pre-
    NPEBC) (no longer active)
      PAR-00-102 - Released June 29, 2000
      Receipt Dates: November 27, March 27, and July 27
       BISTIC Programs (2)
•   Innovations in Biomedical Information
    Science and Technology: Phased
    Innovation Award: R21/R33
      PA-00-117 - Released June 29, 2000
     Receipt Dates: November 27, March 27, and July 27


•   Innovations in Biomedical Information
    Science and Technology: SBIR/STTR
      PA-00-118 - Released June 29, 2000
     Receipt Dates: November 27, March 27, and July 27
           Trans-NIH Bioengineering
            Research Opportunities

• NIH Bioengineering Consortium (BECON)
• Established – February 1997
• Consists of representatives of all NIH institutes,
  centers, and offices and other Federal agencies
• Goal is to to promote and coordinate
  bioengineering research across the NIH
• Administered by the NIBIB
• Chair – Jeff Schloss (NHGRI)
• www.becon.nih.gov
      BECON Programs (1)

• Bioengineering Research Grants (BRG)
     PA-02-011 - Released October 11, 2001
     Receipt Dates: February 1, June 1 and October 1


• Bioengineering Research Partnerships (BRP)
     PAR-03-032 - Released November 20, 2002
     Receipt Dates: January 23, 2003 and August 22, 2003
      BECON Programs (2)

• Exploratory/Developmental Bioengineering
  Research Grants (EBRG)
     PA-03-058 - Released January 16, 2003
     Receipt Dates: February 1, June 1, and October 1


• Nanoscience and Nanotechnology
  in Biology and Medicine
     PAR-03-045 - Released December 12, 2002
     Receipt Dates: February 18 and August 18
        Bioengineering Research
             Partnerships

• R01 awards – special review
• Requires a multi-disciplinary research team
  applying an integrative, systems approach to
  address a biomedical problem
• Receipt Dates: January 23, 2003 and August
  22, 2003
• 104 BRP awards - Average award - $880k
• PAR-03-032
    Bioengineering Research Grants

• R01 awards – Apply basic bioengineering
  design-directed or hypothesis-driven research
  to an important biomedical area.
• Aimed at single or small groups of
  researchers
• Receipt Dates: February 1, June 1, October 1
• 152 BRG awards – Average award - $300k
• PA-02-011
         Exploratory/Developmental
   Bioengineering Research Grants (EBRG)

• R21 awards – exploratory or developmental
  bioengineering research that is not
  appropriate for the R01 grant mechanism
• Receipt Dates: February 1, June 1, October 1
• Award limit - $ 275k over two years
• PA-03-058
            The Human Brain Project
               (Neuroinformatics)

   PAR-03-035                   PAR-03-036
   • Phase I - Feasibility      • Innovative
   • Phase II -                   Exploratory Studies
     Refinements,                 and Technology
     Maintenance and              Development
     Integration                • R21 mechanism
   • R01, P01, P20
     mechanisms

Application receipt dates: January 21, May 21, and September 22
  NIBIB Current FY03 RFAs
• Improvements in Imaging Methods and
  Technologies
• Telehealth Technologies Development
     Improvements in Imaging
     Methods and Technologies
  – RFA EB-03-007
  – Application receipt date: March 24
  – Approximately $8 million anticipated
  – R01 and R21 mechanisms
Goal: To develop technological and method-
ological approaches that improve and extend the
sensitivity, spatial and temporal resolution, and
“information content” of individual imaging
techniques
         Telehealth Technologies
              Development
  –   RFA EB-03-005
  –   Application receipt date: March 13
  –   Approximately $5 million anticipated
  –   R01 and R21 mechanisms
  –   SBIR/STTR version (PA-03-030)
Goal: To develop technical solutions to issues
which arise in the diagnosis, treatment, and
follow-up with a patient at a distance
     Upcoming Workshops
• NIBIB Workshop on Modeling and
  Simulation – July 2003,Contact Grace
  Peng
• BECON 2003 Symposium:
  Catalyzing Team Science – June 2003
        NIBIB Workshop on
       Modeling and Simulation
• Planned for July 2003

• Topics to be Covered:
  – new models and analysis for currently modeled
    systems, diseases, and problems
  – models and analysis for new phenomenon that
    have never been modeled
  – cross-coupling techniques
  – cross-coupling modelers, signal processors
  – multi-scale modeling of biological and
    physiological systems
            BECON 2003 Symposium:
            Catalyzing Team Science
• June 23-24, 2003 – NIH Natcher Conference Center

• 6th in a series of annual BECON (Bioengineering
  Consortium) Symposia
   Biosensors (2002), Reparative Medicine (2001), Nanotechnology
   (2000), Bioimaging (1999), Bioengineering (1998)

• Symposium Goal: To examine the forces encouraging
  and discouraging team approaches in biomedical
  research, and to explore new ways in which NIH,
  academia and others can work together to stimulate
  and reward team efforts.

   –NIH Chair: Dan Sullivan (NCI)
   –Extramural Co-Chairs: H. Keith Brodie, MD (Duke)
                          Janie Fouke, PhD (Michigan State)
       NIBIB Future Directions

• Bioengineering and biomedical imaging
  research training
• Tissue engineering and regenerative
  medicine
• Functional cell imaging
• Biomedical optics: In vivo monitoring
  and imaging applications

				
DOCUMENT INFO
Shared By:
Categories:
Tags:
Stats:
views:1
posted:2/16/2012
language:
pages:29