Department of Pharmacology

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Department of Pharmacology PHAR2002: General and systematic Pharmacology 2008/2009 Lectures/Tutorials are on Mondays at 11.00 a.m. and selected Wednesdays at 10.00 a.m. and on Fridays at 11.00 a.m. Lectures will be held in the AV Hill Lecture Theatre unless indicated otherwise. TERM 1 Sep 26 Fri Introduction. Drug targets, selective toxicity, therapeutic index. TSS Sep 29 Mon Receptor structure. NSM Oct 1 Wed Basic principles of pharmacokinetics. Drug absorption. MS Note: Lecture will be in the Darwin Lecture Theatre Oct 3 Fri Transduction mechanisms. TDC Oct 6 Mon The peripheral nervous system. AHD Oct 8 Wed Tutorial (1) TSS, GWJM, LGS, DW, NSM, JAP, AGR, RB, DCHB, AH Oct 10 Fri Dose-response curves. Affinity and efficacy. AJG Oct 13 Mon Drug antagonism. AJG Oct 15 Wed Drug distribution. MS Note: Lecture will be in the Darwin Lecture Theatre Oct 17 Fri Cholinergic pharmacology I. LGS Oct 20 Mon Cholinergic pharmacology II. LGS Oct 22 Wed Tutorial (2) TSS, GWJM, LGS, DW, NSM, JAP, AGR, RB, DCHB, AH Oct 24 Fri Adrenergic pharmacology I. SCS Oct 27 Mon Adrenergic pharmacology II. SCS Oct 29 Wed Drug excretion. MS Note: Lecture will be in the Darwin Lecture Theatre Oct 31 Fri Smooth muscle pharmacology. TDC Nov 3 Mon Local anaesthetics. Antidysrhythmic drugs. MF Nov 5 Wed Tutorial (3) TSS, GWJM, LGS, DW, NSM, JAP, AGR, RB, DCHB, AH Nov 7 Fri Antianginal drugs. Cardiac glycosides. AGR Nov 10 Mon Diuretics. AGR Nov 12 Wed The metabolism of drugs. MS Note: Lecture will be in the Darwin Lecture Theatre Nov 14 Fri Antihypertensive drugs. AGR Nov 17 Mon Atherosclerosis and lipid lowering drugs. AH Nov 19 Wed Kinetics of drug absorption and elimination. MS Note: Lecture will be in Bentham House (Bentham MLT) Nov 21 Fri Histamine and other mediators of inflammation. DW Nov 24 Mon Anticoagulants. Fibrinolytics SCS Nov 26 Wed Tutorial (4) TSS, GWJM, LGS, DW, NSM, JAP, AGR, RB, DCHB, AH Nov 28 Fri Antihistamines. Treatment of peptic ulcers. DW Dec 1 Mon Eicosanoids. DW Dec 3 Wed Pharmacokinetics Test TSS Note: Test will be held in Bentham House (Bentham MLT) Dec 5 Fri Anti-inflammatory drugs. DW Dec 8 Mon Drugs used to treat asthma. DW Dec 10 Wed Tutorial (5) TSS, GWJM, LGS, DW, NSM, JAP, AGR, RB, DCHB, AH Dec 12 Fri Free End of term I PHAR2002_B15-08-09_w_notes_E.doc (6/10/2008) 6 TERM 2 Jan 12 Jan 14 Mon Wed Free TEST Note: Test will be held in Bedford Way G03 (26, Bedford Way) Pharmacological control of fertility. Insulin and oral antidiabetic agents. Clinical trials. Note: Lecture will be in Bedford Way G03 (26, Bedford Way) Chemotherapy: anti-bacterial drugs, I. Chemotherapy: anti-bacterial drugs II, anti-fungal drugs. Tutorial (6) AJG, AHD, SCS, MF, AGR, PV, PT, TSS, RB, DCHB (Test follow-up) Chemotherapy: anti-viral drugs Chemotherapy: anti-cancer drugs. Free Introduction to neuropharmacology. Aminoacid neurotransmitters. Benzodiazepines. Tutorial (7) AJG, AHD, SCS, MF, AGR, PV, PT, TSS, RB, DCHB Parkinson’s disease and other motor disorders. Schizophrenia. Anti-emetics. Free Anxiolytics. Drugs used in affective disorders. Tutorial (8) AJG, AHD, SCS, MF, AGR, PV, PT, TSS, RB, DCHB Anti-epileptics. Analgesics. Free General anaesthetics. Mechanism of action of ethanol. Non-medical use of drugs, dependence. Tutorial (9) AJG, AHD, SCS, MF, AGR, PV, PT, TSS, RB, DCHB Anti-obesity drugs. Drug toxicity. Free Relationship between chemical structure and pharmacological activity. Free Tutorial (10) AJG, AHD, SCS, MF, AGR, PV, PT, TSS, RB, DCHB End of Lectures Revision Workshop 1 – General Pharmacology and Autonomic Revision Workshop 2 – Inflammation and Chemotherapy Revision Workshop 3 – Neuropharmacology TSS Jan 16 Jan 19 Jan 21 Jan 23 Jan 26 Jan 28 Jan 30 Feb 2 Feb 4 Feb 6 Feb 9 Feb 11 Feb 13 Feb 16 Feb 18 Feb 20 Feb 23 Feb 25 Feb 27 Mar 2 Mar 4 Mar 6 Mar 9 Mar 11 Mar 13 Mar 16 Mar 18 Mar 20 Mar 23 Mar 25 May 1 May 1 May 1 Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri Mon Wed Fri 12.00 Fri 14.00 Fri 16.00 PAV TSS AHD TSS TSS DW DW AHD MF AHD SCS SCS SCS MF AHD ACD SCS SCS TSS TSS TSS AJG DW TSS PHAR2002_B15-08-09_w_notes_E.doc (6/10/2008) 7

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