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					NHMRC RESEARCH INTO HAEMOCHROMATOSIS RELATED ISSUES 2000-2010
      Type                  2000            2001            2002               2003       2004         2005         2006         2007         2008         2009         2010
Haemochromatosis
                           $99,545       $162,740         $610,720        $1,130,173    $1,334,060   $1,387,767   $1,466,946   $1,921,746   $2,370,529   $2,976,607   $2,462,258
by CY
Report Run: 18 Dec 06/Updated 20 May 07/4 Aug 08/Updated 19 Jun 09/2 Jun 10
Sources: Extracted from NHMRC Databases - RGMS/RMIS/GMS as at Jun 10

Haemochromatosis           2000-01        2001-02          2002-03            2003-04    2004-05      2005-06      2006-07      2007-08      2008-09      2009-10      2010-11
by FY
                       $184,039      $388,487      $876,692     $1,226,213 $1,348,894 $1,428,563             $1,744,083 $2,031,940 $2,750,799            $2,718,627 $2,197,595
Methodology: NHMRC Research funding datasets rely entirely on the information provided by the Chief Investigators through the application process. Decisions on allocation to
particular disease and health issue datasets are made subjectively by the NHMRC Evaluation and Reporting Section (supported by other internal review mechanisms) based on the
information provided. The key search parameters listed above form the basis of the coverage of this dataset. Lay descriptions, where available have also been reviewed to support
the allocation.
Keywords: haemochromatosis, hemochromatosis, iron overload
Grant Types:Includes all grant types except IRIISS and equipment grants
Fields of Research: All
GMS Codes: Cat B - Not Applicable
GMS Admin Type: NH PH
GMS Budget Type: 4
GMS App ID range: 900000 - 009999
Status: Accepted, Approved, Payments can be made, Suspended, Terminated, Completed
Where: Start Year >= 2000
Pay Type: Calendar year budgets. Excludes claims. Excludes GST
Note: All figures shown are the cash amounts awarded to recipients in the calender year
Data source: These data are sourced from the pre 2000 NHMRC Grants Management Systems (GMS) and post 1999 NHMRC Research
NHMRC FUNDED RESEARCH INTO HAEMOCHROMATOSIS 2000 - 2010
Keywords: haemochromatosis, hemochromatosis, iron overload
Report Run: 18 Dec 06/Updated 20 May 07/4 Aug 08/Updated 19 Jun 09/2 Jun 10
Sources: Extracted from NHMRC Databases - RGMS/RMIS/GMS as at Jun 10
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with research into Haemochromatosis
through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the research area in question may
be either immediate or be a longer term perceived benefit. This dataset was current as at 2 Jun 10 but is subject to change over time.
Summary of Expenditure :Haemochromatosis
     2000             $99,545 Actual Expenditure            2 grants                         NHMRC Research Funding 2000-2010
     2001            $162,740 Actual Expenditure            3 grants
                                                                                                       Haemochromatosis
     2002            $610,720 Actual Expenditure            9 grants
     2003          $1,130,173 Actual Expenditure            11 grants
     2004          $1,334,060 Actual Expenditure            11 grants        $3,000,000
     2005          $1,387,767 Actual Expenditure            7 grants         $2,500,000
     2006          $1,466,946 Actual Expenditure            9 grants
     2007          $1,921,746 Actual Expenditure            10 grants        $2,000,000
     2008          $2,370,529 Actual Expenditure            14 grants
                                                                             $1,500,000
     2009          $2,976,607 Actual Expenditure            19 grants
     2010          $2,462,258 Forecast Expenditure          19 grants        $1,000,000
    Total         $15,923,091 As at Dec 10
                                                                                $500,000
     2011          $1,968,682 Forward commitments           15 grants
     2012           $865,026 Forward commitments            6 grants                  $0
     2013           $210,725 Forward commitments            2 grants                     2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
    Total         $18,967,524 Includes out years
2. Forward commitments funding data for out-years (ie beyond 2010) is subject to change when new grants are awarded in subsequent years


 Grant Id        CIA Full Name              RMIS Grant Type               RMIS Grant Subtype   Scientific Title       Simplified Title           Admin Inst

     7079    Dr Bettina Meiser                                  Public Health (Australia) Fellowship SCREENINGGENETIC SCREENING FOR HAEMOCHROMATOSIS: DETERMI
                                   Training Fellowship (Australia)                         GENETIC                                          University of New South Wales
                                                                                                                    FOR HAEMOCHROMATOSIS: DETERMINATS OF UPTAKE OF
   110282    Dr Deborah Trinder NHMRC Project Grants            Standard Project Grant                             Iron Metabolism in the HFE Knockout
                                                                                                                                            University of Western Australia
                                                                                           The Pathogenesis of Haemochromatosisin Haemochromatosis Mouse Model
   164200    Dr Katherine A Stuart Scholarship                                             Iron Overload in End-stage Liver Disease: Mechanisms,Alexandra Mechanisms, Pathophys
                                                                Medical Postgraduate Scholarship                                            Princess Disease: Hospital
                                                                                                                   Iron Overload in End-stage Liver Pathophysiological Significance a
   189720    Prof Des R RichardsonNHMRC Project Grants          Standard Project Grant                             Freidreich's ataxia and iron The role of Institute
                                                                                                                                             Heart Research
                                                                                           Mitochondrial iron overload and Friedreich's ataxia: metabolismfrataxin in iron and haem m
   210159                          NHMRC Project Grants
             Prof Darrell HG Crawford                           Standard Project Grant                              cirrhotic liver:studies on
                                                                                                                                             University of Queensland
                                                                                           Iron metabolism and theIron and the cirrhotic liveriron absorption and hepatic iron kinetics
211910   A/Pr Erica Baker       NHMRC Career Awards      NHMRC Research Fellowship                           Uncoupled Reseach Fellowship of Western Australia
                                                                                  Uncoupled Reseach Fellowship                       University
211940   Dr Phillip S OATES     NHMRC Project Grants     Standard Project Grant                              How iron is absorbed by the intestine
                                                                                                                                     University of Western and hemochromatos
                                                                                  The role of transferrin receptor, divalent metal transporter, ferroportinAustralia
211947                          NHMRC Project Grants
         A/Pr Timothy G St Pierre                        Development Grant                                   Non-invasive measurement and imaging of liver iron nuclear magn
                                                                                                                                     University of Western Australia
                                                                                  Non-invasive measurement and imaging of hepatic iron concentrations usingconcentration
212116   Ms Anita C Chua        Scholarship                                       Characterization of molecular mechanisms of iron overload Western Australia the in hepa
                                                         Biomedical Postgraduate Scholarship                                         University of in hepatocytes from
                                                                                                             Characterization of molecular mechanisms of iron overload HFE kn
251668   Dr Dorota Gertig       NHMRC Project Grants     Standard Project Grant                              What environmental risk University of Melbourne
                                                                                  Epidemiology of Hereditary Haemochromatosis factors modify hereditary haemochromato
254594   Dr Elizabeth A Milward NHMRC Project Grants     Standard Project Grant                              Iron and Memory
                                                                                  Iron and Cognition in Older Adults               University of Western Australia
254609   Dr Deborah Trinder NHMRC Project Grants         Standard Project Grant                              Iron transport in haemochromatosishepatic iron transport in heredit
                                                                                                                                     University of
                                                                                  Characterisation of the mechanisms of gastrointestinal and Western Australia
290227   A/Pr Gregory J AndersonNHMRC Career Awards      NHMRC Research Fellowship                           Uncoupled               Queensland
                                                                                  Uncoupled Research Fellowship Research Fellowship Institute of Medical Research
339400   Prof Lawrie W Powell ACProgram                  New Program Grant                                   Iron Metabolism and Liver Disease Institute of Medical Research
                                                                                  Iron Metabolism and Liver Disease                  Queensland
350874   Prof Des R RichardsonNHMRC Project Grants       Standard Project Grant                              Mitochondrial Iron Overload The New South Wales
                                                                                                                                    Ataxia:
                                                                                  Mitochondrial Iron Overload and Friedreich'sUniversity of Role of Frataxin in Iron and Haem
384460   Dr Katrina J Allen     Career Development AwardsClinical CDA                                        Development of liver and for the treatment of
                                                                                                                                     Murdoch Childrens Research Institute
                                                                                  Development of liver and stem cell transplantationstem cell transplantation for the treatmen
389888   A/Pr Gregory J AndersonNHMRC Project Grants     Standard Project Grant                              Intestinal haem iron absorption
                                                                                                                                     Queensland Institute of Medical Research
                                                                                  The mechanism of intestinal haem iron absorption and characterization of a novel haem-bi
404021   Dr Deborah Trinder NHMRC Project Grants         Standard Project Grant                              Iron overload in of hereditary haemochromatosis
                                                                                                                                     University of Western Australia
                                                                                  The role of the liver in the pathogenesis hereditary haemochormatosis
404166                          S
         Dr Oyekoya T Ayonrinde cholarship                                        The epidemiology and significance of hepatic & gastroenterological conditions among adol
                                                         Medical Postgraduate Scholarship                                            significance Western & gastroenterologica
                                                                                                             The epidemiology and University of of hepaticAustralia
442913   A/Pr Gregory J AndersonNHMRC Career Awards      NHMRC Research Fellowship                           Uncoupled               Queensland
                                                                                  Uncoupled Research Fellowship Research Fellowship Institute of Medical Research
443026   Dr Daniel F Wallace Career Development Awards   Biomedical CDA                                      Hepcidin: The link between cytokines, anaemia
                                                                                                                                     Queensland Institute of Medical Research
                                                                                  Hepcidin: The link between cytokines, haemochromatosis and haemochromatosis and ana
455985   Dr Julie R Jonsson     NHMRC Project Grants     Standard Project Grant                              A new model progenitor in chronic liver disease
                                                                                                                                     University of Queensland
                                                                                  Hepatocyte replicative arrest, hepatic for fibrosis cells and the ductular reaction in hepatic f
456073   Dr Richard J Clark     NHMRC Project Grants     Standard Project Grant                              Stable peptide-based therapeutics
                                                                                                                                     University peptide-based
                                                                                  Development of a generic strategy for the stabilisation of of Queensland therapeutics
491224   A/Pr Martin B DelatyckiNHMRC Project Grants     Standard Project Grant                              Is high-school haemochromatosis acceptable and feasible?
                                                                                                                                     Murdoch Childrens Research Institute
                                                                                  Is high-school screening for hereditary screening for haemochromatosis acceptable and fea
496730   Dr Marnie J Wood       Scholarship                                       Clinical                   Clinical the Progression to Institute Progression to Cirrhosis in He
                                                                                                                             Queensland Cirrhosis in Hemochromatosis
                                                         Medical Postgraduate Scholarship and Genetic Modifiers inand Genetic Modifiers in the of Medical Research
508085   Prof Sharad Kumar NHMRC Project Grants          Standard Project Grant                              Study adaptors for theUniversity of cellubiquitin ligases disease
                                                                                                                                      Nedd4 family of physiology and
                                                                                  Roles of Ndfip1 and Ndfip2 as of novel regulatory proteins inAdelaide
509174   Dr Lyle C Gurrin       NHMRC Project Grants     Standard Project Grant                              Treatment effectiveness the prevention of hereditary haemochrom
                                                                                                                                     University of Melbourne
                                                                                  Early versus delayed therapeutic venesection forfor hereditary haemochromatosis
513761   Prof John K Olynyk     NHMRC Career Awards      Practitioner Fellowship  Practitioner Fellowship Practitioner FellowshipUniversity of Western Australia
519739   Dr Richard J Clark     Career Development AwardsBiomedical CDA                                      Effective peptide drugs
                                                                                  Development of effective peptide-based drugs University of Queensland
546452   A/Pr Martin Delatycki NHMRC Career Awards       Practitioner Fellowship                             Uncoupled          Murdoch Childrens Research Institute
                                                                                  Uncoupled Research Fellowship Research Fellowship
552409   A/Pr Grant A Ramm NHMRC Career Awards           NHMRC Research Fellowship                           Uncoupled       Queensland Institute of Medical Research
                                                                                  Uncoupled Research Fellowship Research Fellowship
552412   Dr Daniel F Wallace NHMRC Project Grants                                 Non-HFE haemochromatosis in Australia: natural history and molecularResearch
                                                         Priming Grant (New Investigator)                                    Queensland Institute of Medical characterisation
                                                                                                             Non-HFE haemochromatosis
552430   Prof Gregory J AndersonNHMRC Project Grants     Standard Project Grant                              Iron metabolism and consequences of iron supplementation during
                                                                                                                             Queensland Institute of
                                                                                  Mechanisms of intestinal iron absorption in the perinatal period Medical Research
566555   A/Pr Graham Baldwin NHMRC Project Grants        Standard Project Grant                              Gastrin, Iron           University of
                                                                                  Gastrin, Iron and Colorectal Cancer and Colorectal CancerMelbourne
570844   Dr Rachel Codd         NHMRC Project Grants                              Affinity-based profiling of bacterial Fe(III)-siderophore receptors: design strategies for strate
                                                         Priming Grant (New Investigator)                                               University of Sydney
                                                                                                             Understanding iron-uptake mechanisms in bacteria to inform antib
572601   A/Pr Deborah Trinder NHMRC Project Grants       Standard Project Grant                              Liver iron transport haemochromatosis
                                                                                                                                   University of Western Australia
                                                                                  Regulation of liver iron loading in hereditaryin hereditary haemochromatosis
613643                          NHMRC
         A/Pr V. Nathan Subramaniam Project Grants       Standard Project Grant                              The Role of Matriptase-2 and Hemojuvelin ofHEMOJUVELIN,
                                                                                                                                      MATRIPTASE-2 AND Medical Research
                                                                                  EXAMINING THE RELATIONSHIP BETWEENQueensland Institutein Iron Metabolism TW
613688   Prof Gregory J AndersonNHMRC Project Grants     Standard Project Grant                              Anaemia and iron homeostasis.
                                                                                                                                     Queensland
                                                                                  Red cell disorders and the regulation of iron homeostasis Institute of Medical Research
613689   Prof Gregory J AndersonNHMRC Project Grants     Standard Project Grant                              Oxidant stress in iron loading diseases
                                                                                                                                     Queensland Institute of Medical Research
                                                                                  Assessment of oxidant stress and mitochondrial dysfunction in young adults with iron loadi
628697   Dr Lyle C Gurrin       NHMRC Project Grants     Standard Project Grant                              Risk iron overload-related disease Melbourne
                                                                                                                                     University of in a disease
                                                                                  Environmental risk factors forfactors for hereditary iron-overload cohort study of hereditary
    App    Start
State            2000     2001      2002      2003      2004      2005   2006   2007   2008   2009   2010   2011
    Year   Year
NSW 1999   2000 $25,840   $53,395   $56,588   $63,500   $64,750
WA  1999   2000 $73,705   $82,090   $88,822
QLD 2000   2001           $27,255   $21,336    $6,604
NSW 2001   2002                     $95,330   $95,330   $95,330
QLD 2001   2002                     $85,660   $85,660   $85,660
WA    2001   2002    $63,000    $65,850    $67,200    $68,700    $70,050
WA    2001   2002    $65,330    $65,330    $65,330
WA    2001   2002   $115,440   $115,440   $110,330
WA    2001   2002    $19,214    $19,659    $10,485
VIC   2002   2003              $321,300   $368,975   $141,020    $37,500
WA    2002   2003              $133,250   $206,500   $133,250
WA    2002   2003              $158,250   $158,250   $158,250
QLD   2003   2004                         $101,250   $103,500   $105,500    $26,875
QLD   2004   2005                                    $631,547   $643,546   $643,546   $683,073   $683,606
NSW   2004   2005                                    $151,500   $151,500   $303,000
VIC   2005   2006                                                $49,500    $50,250    $76,875    $78,188    $78,188
QLD   2005   2006                                               $185,500   $174,325   $177,948
WA    2005   2006                                               $193,250   $197,325   $201,448
WA    2005   2006                                                $30,600
QLD   2006   2007                                                          $119,000   $121,500   $123,750   $123,750   $123,750
QLD   2006   2007                                                           $90,500    $92,500    $94,250    $94,250    $94,250
QLD   2006   2007                                                          $172,250   $175,821   $179,612
QLD   2006   2007                                                          $144,675   $147,657   $150,865
VIC   2007   2008                                                                     $200,700   $199,864   $199,864   $119,875
QLD   2007   2008                                                                      $17,127    $20,976    $15,231
SA    2007   2008                                                                     $204,050   $239,814   $208,571
VIC   2007   2008                                                                      $96,905    $99,107
WA    2007   2008                                                                      $82,425    $84,175    $84,175    $84,175
QLD   2007   2008                                                                      $92,500    $94,250    $94,250    $94,250
VIC   2008   2009                                                                                $100,975   $100,975   $100,975
QLD   2008   2009                                                                                $112,000   $109,750   $109,750
QLD   2008   2009                                                                                 $96,850    $81,550
QLD   2008   2009                                                                                $172,400   $172,400   $172,400
VIC   2008   2009                                                                                $132,075   $134,583   $134,583
NSW   2008   2009                                                                                 $96,850    $86,650    $86,650
WA    2008   2009                                                                                $217,000   $217,000   $217,000
QLD   2009   2010                                                                                           $174,757   $174,757
QLD   2009   2010                                                                                           $198,194   $198,194
QLD   2009   2010                                                                                           $197,175   $197,175
VIC   2009   2010                                                                                            $90,945    $60,898
$99,545 $162,740 $610,720 $1,130,173 $1,334,060 $1,387,767 $1,466,946 $1,921,746 $2,370,529 $2,976,607 $2,462,258 $1,968,682
   2       3        9         11         11         7          9          10         14         19         19         15
                         Broad Research        Field Of     Research Research Research Research Research Health                      Health     Health
2012   2013   Total
                                Area          Research         KW 1        KW 2        KW 3       KW 4        KW 5        KW 1        KW 2       KW 3
              $264,073   Public Health                      ATTITUDES
                                            Health Counselling                      HAEMOCHROMATOSIS
                                                                        GENETIC TESTING
              $244,617   Basic Science      Hepatology                  Hepatocytes and Kupffer Cells
                                                                                               Iron Metabolism
                                                            Haemochromatosis Intestinal Absorption Liver Disease                   Iron Overload
                                                                                                                       Haemochromatosis Liver Disease
               $55,195                      Medical and     Fibrosis    Iron absorption classified disease
                                                                                    Lipid      Liver
                         Clinical Medicine and Science Health Sciences not elsewhere peroxidation          Liver transplantation
              $285,990   Basic Science                                    ataxia    iron       neurodegenerative diseaselevels neurological disease
                                            Cell Physiology Friedreich'siron chelators metabolism                      iron                   therapeutics
              $256,980                      Gastroenterology and Hepatology
                         Clinical Medicine and Science                  Iron absorption in cholestatic and hepatocellular cirrhosisLiver
                                                                                                                       Cirrhosis
                                                            Hepatic Ferrokinetics Pathophysiology of iron overload in liver cirrhosis disease Liver transplantation
                     $334,800    Basic Science      Hepatology                    Haemochromatosis Liver
                                                                    Chelation therapy         Iron metabolism          Liver cancer
                     $195,990    Basic Science      Gastroenterology              Iron transport                       molecular Anaemia Haemochromatosis
                                                                    Intestinal absorption Physiology haemochromatosis mechanisms                             Intestinal
                     $341,210                       Gastroenterology and Hepatology
                                 Clinical Medicine and Science      cirrhosis haemochromatosisiron         liver                   haemochromatosis
                                                                                                                                                iron levels iron overload
                                                                                                                       magnetic resonance imaging
                       $49,358   Basic Science      Gastroenterology              Hereditary Iron transport
                                                                    HFE knockout mouse haemochromatosis
                     $868,795    Public Health                                    molecular epidemiology
                                                    Epidemiology hereditary haemochromatosis  risk factors                         epidemiology              iron overload
                                                                                                                                                genetic susceptibility
                     $473,000                       Mental Health Genetic polymorphisms
                                 Clinical Medicine and Science                    Haemochromatosis Molecular epidemiology assessment
                                                                                              Iron                                 Epidemiology
                                                                                                                       Neurocognitive                        I
                                                                                                                                                Gerontologyron levels
                     $474,750    Basic Science      Gastroenterology and Hepatology
                                                                    Haemochromatosis Iron metabolism
                                                                                  Instestine               Liver                                Iron overloadLiver disease
                                                                                                                                   Hereditary haemochromatosis
                     $337,125                       Gastroenterology
                                 Clinical Medicine and Science                    intesinal iron
                                                                    haemochromatosis absorption trace element metabolism
                    $3,285,318                      Hepatology
                                 Clinical Medicine and Science                    Hepatic     Iron         Iron
                                                                    Haemochromatosis fibrosis absorption overload      Regulation of iron metabolism
                     $606,000    Basic Science                      haem metabolism
                                                    Therapies and Therapeutic iron Technology neurodegenerative disease reactions
                                                                                                           oxidative stress
                                                                                                                       redox                      ataxia
                                                                                                                                   Friedreich'sataxia        neurodegenerative disease
                     $333,001                       Gastroenterology
                                 Clinical Medicine and Science                    hepatocytes
                                                                    haemochromotosis          liver cell stem cell transplantation
                     $537,773    Basic Science      Gastroenterologyhaem          intestinal absorption nutrient transport
                                                                                              iron                     physiology haemochromatosis           iron
                                                                                                                                                iron deficiency overload
                     $592,023    Basic Science      Gastroenterology and Hepatology
                                                                    haemochromatosis
                                                                                  intestine iron metabolismliver                                inherited disorders
                                                                                                                                                             iron overload
                                                                                                                                   hereditary haemochromatosis
                       $30,600                      Gastroenterology
                                 Clinical Medicine and Science                    hereditary haemochromatosisliver disease
                                                                    Coeliac disease           nonalcoholic fatty
                     $611,750                       Gastroenterology
                                 Clinical Medicine and Science                    Haematology
                                                                    Gastroenterology                       Inherited Iron metabolism
                                                                                              Haemochromatosis metabolic diseases
                     $465,750    Basic Science                      B             Digestive System
                                                    Medical Genetics lood Disorders
                     $527,683                       Hepatology
                                 Clinical Medicine and Science                    hepatic
                                                                    ductular reaction fibrosishepatic progenitor cells                          fatty liver hemochromatosis
                                                                                                                                   chronic liver disease disease
                     $443,197    Basic Science                      Drug delivery  Technology
                                                    Therapies and Therapeutic haemochromatosis drug design peptides
                                                                                              rational     regulatory                           new approaches to drug design
                                                                                                                                   haemochromatosis          therapeutics
                     $720,303                       Preventive Medicine
                                 Preventative Medicine                            G
                                                                    Adolescents enetic screening
                                                                                              Preventative Medicine
                                                                                                           School health promotion              Haemochromatosis
                                                                                                                                   Genetic screening         Health promoting schools
                       $53,334                      Gastroenterology and Hepatology epidemiology pathophysiology
                                 Clinical Medicine and Science      SNP           clinical    genetic polymorphismspolymerase chain reaction (PCR)
                     $652,435    Basic Science      Protein Targeting and Signal Transduction transport
                                                                    Nedd4 family ofdeath- apoptosis protein-protein interaction
                                                                                  cell ubiquitin ligases
                                                                                              iron                                              disease mechanisms
                                                                                                                                                             haemochromatosis
                                                                                                                       ubiquitin biochemistry and molecular biology
                     $196,012    Public Health      Epidemiology Cohort Studies               Haemochromatosis Statistics                       Genetic Screening
                                                                                                                                                              To Disease
                                                                                  Genetic Predisposition Preventative Medicine Genetic Predisposition Hereditary Haemochromatosis
 $84,175             $419,125    Clinical Medicine and Science
                                                    Gastroenterology physiology
                                                                    Cell                      Gastroenterology,Gene expression
                                                                                  Colorectal cancer                    haemochromatosis,
                                                                                                           Oncology, Hepatocarcinogenesis
                     $375,250    Basic Science                      antibiotics chronic Peptides
                                                                                              hemochromatosis
                                                    Medical Biochemistry: Proteins andpain and analgesia
$100,975 $100,975    $504,875                       Medical Genetics linical trial, Genetic screening, Preventative Pharmacological intervention, Genetic screening
                                 Clinical Medicine and Science      C                                      Incurable progressive neurological disease
                                                                                  Friedreich's ataxia, Haemochromatosis
$109,750 $109,750    $551,000                       Hepatology
                                 Clinical Medicine and Science      Cystic Fibrosis, Hepatic stellatefibrosis, Bile acids Cholestatic liver disease, Biliary Atresia
                                                                                  Cytokines and chemokines metab
                                                                                              Hepatic cell, Iron fibrosis,
                                                                                                           Hepatic     Hereditary haemochromatosis,
                     $178,400    Basic Science                      genetics haemochromatosis
                                                    Genetics not elsewhere classified         iron metabolism
                                                                                                           liver                   haemochromatosis
                                                                                                                       molecular basis                       iron overload
                                                                                                                                                hyperferritinaemia
                     $517,200    Basic Science                      intestinal absorption iron supplementation pregnancy iron deficiency overload
                                                                                  iron
                                                    Gastroenterology and Hepatology                        neonate                              iron         neonate
                     $401,241    Basic Science      Gastroenterologycolorectal cancer
                                                                                  gastrin     iron                                              gastroenterology
                                                                                                                                   colorectal cancer (CRC)   gastrointestinal tumorigenesis
                     $270,150    Basic Science      Medical Biochemistry: Proteins and Peptides
                                                                    Affinity-based proteindevelopmentFe(III)-siderophore cell-surface receptor proteins bacteria disease and beta
                                                                                  Antibiotic profiling
                                                                                              Compounds to treat iron-overload Controlling Development in biofilms
                                                                                                                                    disease the formation    Iron-overload
                                                                                                                       Siderophores and Fe(III) acquisition of antibiotics
                     $651,000    Basic Science      Hepatology      Hereditary haemochromatosis
                                                                                  inflammation metabolism
                                                                                              iron         liver                   alcoholic liver diseasehaemochomatosis
                                                                                                                       oxidative stress         hereditary iron overload
$174,757             $524,271    Basic Science      Gastroenterology and Hepatology
                                                                    haemochromatosis
                                                                                  iron metabolism
                                                                                              liver                    proteases anaemia blood disorders
                                                                                                           molecular mechanisms                              haemochromatosis
$198,194             $594,582    Basic Science      Haemotology haemolytic hepcidin iron homeostasis
                                                                                  anaemia                              macrophage iron metabolism
                                                                                                           iron kinetics                        anaemia iron overload
                                                                                                                                   haemolytic hereditary spherocytosis
$197,175             $591,525    Clinical Medicine and Science
                                                    Gastroenterology and Hepatology fibrosis overload diseasesoxidative stress
                                                                    haemochromatosis
                                                                                  hepatic     iron         mitochondria                         iron overload diseases
                                                                                                                                   haemochromatosis          liver disease
                     $151,843    Public Health      Epidemiology Cohort Studies               Haemochromatosis Statistics                       Genetic Predisposition To Disease
                                                                                  Genetic Predisposition Preventative Medicine Environmental modifiers       Genetic Screening
$865,026 $210,725 $18,967,524
   6        2
             Health     Health    Application
                                               Unit Status
             KW 4       KW 5        Status
                                              Payments
                                 Payments can be made can be made
Liver Disease                                 Payments
                                 Payments can be made can be made
                                              Payments
                                 Payments can be made can be made
therapeutics                                  Payments
                                 Payments can be made can be made
Liver transplantation                         Payments
                                 Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
                              Iron
                 Iron deficiency overload                Payments
                                          Payments can be made can be made
                              thalassaemia               Payments
                 iron storage disorder Payments can be made can be made
                                          Terminated     Terminated
                 risk factors                            Payments
                                          Payments can be made can be made
                              Mental health
                                          Payments can Payments
                 Memory related disordersand ageing be made can be made
    Liver disease                                        Payments
                                          Payments can be made can be made
                                          Terminated     Terminated
                                                         Payments
                                          Payments can be made can be made
                              therapeutics               Payments
                 neurological disease Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
                 nutrition                               Payments
                                          Payments can be made can be made
                 liver disease                           Payments
                                          Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
                              hepatitis C Payments can be made can be made
                 hepatic insulin resistance              Payments
    therapeutics                                         Payments
                                          Payments can be made can be made
                              Young people               Payments
                 Preventive screening Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
                              traumatic brain injury can be made can be made
                 iron deficiency          Payments       Payments
                              Treatment Payments         Payments
                 Preventive Medicine Efficacy can be made can be made
                                                         Payments
                                          Payments can be made can be made
                                                         Payments
                                          Payments can be made can be made
Genetic screening                                        Payments
                                          Payments can be made can be made
 Biliary Atresia                                         Payments
                                          Payments can be made can be made
                 liver                                   Payments
                                          Payments can be made can be made
                                                         Payments
                 nutrition pregnancy Payments can be made can be made
    gastrointestinal tumorigenesis                       Payments
                                          Payments can be made can be made
                                          Payments       Payments
    Iron-overload disease and beta-thalassemia can be made can be made
                 liver disease                           Payments
                                          Payments can be made can be made
                                          A
                 iron levels liver disease ccepted       Payments can be made
                 thalassaemia             Accepted       Payments can be made
                 thalassaemia             Accepted       Accepted
                              Preventive Medicine
                                          Payments       Payments
                 Hereditary Haemochromatosis can be made can be made
NHMRC FUNDED RESEARCH INTO HAEMOCHROMATOSIS 2000-01 to 2009-10
Keywords: haemochromatosis, hemochromatosis, iron overload
Report Run: 18 Dec 06/Updated 20 May 07/4 Aug 08/Updated 19 Jun 09/2 Jun 10
Sources: Extracted from NHMRC Databases - RGMS/RMIS/GMS as at Jun 10
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with research into Haemochromatosis
through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the research area in question may
be either immediate or be a longer term perceived benefit. This dataset was current as at 2 Jun 10 but is subject to change over time.
Summary of Expenditure :Haemochromatosis
 2000-01            $184,039 Actual Expenditure                         3 grants
 2001-02            $388,487 Actual Expenditure                         9 grants
 2002-03            $876,692 Actual Expenditure                         12 grants
 2003-04          $1,226,213 Actual Expenditure                         11 grants
 2004-05          $1,348,894 Actual Expenditure                         12 grants
 2005-06          $1,428,563 Actual Expenditure                         12 grants
 2006-07          $1,744,083 Actual Expenditure                         12 grants
 2007-08          $2,031,940 Actual Expenditure                         14 grants
 2008-09          $2,750,799 Actual Expenditure                         22 grants
 2009-10          $2,718,627 Actual Expenditure                         23 grants
 2010-11          $2,197,595 Forecast Expenditure                       18 grants
   Total        $16,895,932 As at Dec 10
 2011-12         $1,433,375 Forward commitments                         15 grants
 2012-13            $544,972 Forward commitments                        6 grants
 2013-14            $108,511 Forward commitments                        2 grants
   Total        $18,982,790 Includes out years

2. Forward commitments funding data for out-years (ie beyond 2010) is subject to change when new grants are awarded in subsequent years


 Grant Id        CIA Full Name              RMIS Grant Type               RMIS Grant Subtype   Scientific Title      Simplified Title           Admin Inst

     7079    Dr Bettina Meiser                                  Public Health (Australia) Fellowship SCREENINGGENETIC SCREENING FOR HAEMOCHROMATOSIS: DETERMI
                                   Training Fellowship (Australia)                         GENETIC                                        University of New South Wales
                                                                                                                    FOR HAEMOCHROMATOSIS: DETERMINATS OF UPTAKE OF
   110282    Dr Deborah Trinder NHMRC Project Grants            Standard Project Grant                             Iron Metabolism in the HFE Knockout
                                                                                                                                          University of Western Australia
                                                                                           The Pathogenesis of Haemochromatosisin Haemochromatosis Mouse Model
   164200    Dr Katherine A Stuart Scholarship                                             Iron Overload in End-stage Liver Disease: Mechanisms,Alexandra Mechanisms, Pathophys
                                                                Medical Postgraduate Scholarship                                          Princess Disease: Hospital
                                                                                                                   Iron Overload in End-stage Liver Pathophysiological Significance a
   189720    Prof Des R RichardsonNHMRC Project Grants          Standard Project Grant                             Freidreich's ataxia and iron The role of Institute
                                                                                                                                            Heart Research
                                                                                           Mitochondrial iron overload and Friedreich's ataxia: metabolismfrataxin in iron and haem m
210159                          NHMRC Project Grants
         Prof Darrell HG Crawford                        Standard Project Grant                               cirrhotic liver:studies on
                                                                                                                                       University of Queensland
                                                                                  Iron metabolism and theIron and the cirrhotic liveriron absorption and hepatic iron kinetics
211910   A/Pr Erica Baker       NHMRC Career Awards      NHMRC Research Fellowship                           Uncoupled Reseach Fellowship of Western Australia
                                                                                  Uncoupled Reseach Fellowship                        University
211940   Dr Phillip S OATES     NHMRC Project Grants     Standard Project Grant                              How iron is absorbed by the intestine
                                                                                                                                      University of Western and hemochromatos
                                                                                  The role of transferrin receptor, divalent metal transporter, ferroportinAustralia
211947                          NHMRC Project Grants
         A/Pr Timothy G St Pierre                        Development Grant                                   Non-invasive measurement and imaging of liver iron nuclear magn
                                                                                                                                      University of Western Australia
                                                                                  Non-invasive measurement and imaging of hepatic iron concentrations usingconcentration
212116   Ms Anita C Chua        Scholarship                                       Characterization of molecular mechanisms of iron overload Western Australia the in hepa
                                                         Biomedical Postgraduate Scholarship                                          University of in hepatocytes from
                                                                                                             Characterization of molecular mechanisms of iron overload HFE kn
251668   Dr Dorota Gertig       NHMRC Project Grants     Standard Project Grant                              What environmental risk  University of Melbourne
                                                                                  Epidemiology of Hereditary Haemochromatosis factors modify hereditary haemochromato
254594   Dr Elizabeth A Milward NHMRC Project Grants     Standard Project Grant                              Iron and Memory
                                                                                  Iron and Cognition in Older Adults                University of Western Australia
254609   Dr Deborah Trinder NHMRC Project Grants         Standard Project Grant                              Iron transport in haemochromatosishepatic iron transport in heredit
                                                                                                                                      University of
                                                                                  Characterisation of the mechanisms of gastrointestinal and Western Australia
290227   A/Pr Gregory J AndersonNHMRC Career Awards      NHMRC Research Fellowship                           Uncoupled                Queensland
                                                                                  Uncoupled Research Fellowship Research Fellowship Institute of Medical Research
339400   Prof Lawrie W Powell ACProgram                  New Program Grant                                   Iron Metabolism and Liver Disease Institute of Medical Research
                                                                                  Iron Metabolism and Liver Disease                   Queensland
350874   Prof Des R RichardsonNHMRC Project Grants       Standard Project Grant                              Mitochondrial Iron Overload The New South Wales
                                                                                                                                     Ataxia:
                                                                                  Mitochondrial Iron Overload and Friedreich'sUniversity of Role of Frataxin in Iron and Haem
384460   Dr Katrina J Allen     Career Development AwardsClinical CDA                                        Development of liver and for the treatment of
                                                                                                                                      Murdoch Childrens Research Institute
                                                                                  Development of liver and stem cell transplantationstem cell transplantation for the treatmen
389888   A/Pr Gregory J AndersonNHMRC Project Grants     Standard Project Grant                              Intestinal haem iron absorption
                                                                                                                                      Queensland Institute of Medical Research
                                                                                  The mechanism of intestinal haem iron absorption and characterization of a novel haem-bi
404021   Dr Deborah Trinder NHMRC Project Grants         Standard Project Grant                              Iron overload in of hereditary haemochromatosis
                                                                                                                                      University of Western Australia
                                                                                  The role of the liver in the pathogenesis hereditary haemochormatosis
404166                          S
         Dr Oyekoya T Ayonrinde cholarship                                        The epidemiology and significance of hepatic & gastroenterological conditions among adol
                                                         Medical Postgraduate Scholarship                                              significance Western & gastroenterologica
                                                                                                             The epidemiology and University of of hepaticAustralia
442913   A/Pr Gregory J AndersonNHMRC Career Awards      NHMRC Research Fellowship                           Uncoupled                Queensland
                                                                                  Uncoupled Research Fellowship Research Fellowship Institute of Medical Research
443026   Dr Daniel F Wallace Career Development Awards   Biomedical CDA                                      Hepcidin: The link between cytokines, anaemia
                                                                                                                                      Queensland Institute of Medical Research
                                                                                  Hepcidin: The link between cytokines, haemochromatosis and haemochromatosis and ana
455985   Dr Julie R Jonsson     NHMRC Project Grants     Standard Project Grant                              A new model progenitor in chronic liver disease
                                                                                                                                      University of Queensland
                                                                                  Hepatocyte replicative arrest, hepatic for fibrosis cells and the ductular reaction in hepatic f
456073   Dr Richard J Clark     NHMRC Project Grants     Standard Project Grant                              Stable peptide-based therapeutics
                                                                                                                                      University peptide-based
                                                                                  Development of a generic strategy for the stabilisation of of Queensland therapeutics
491224   A/Pr Martin B DelatyckiNHMRC Project Grants     Standard Project Grant                              Is high-school haemochromatosis acceptable and feasible?
                                                                                                                                      Murdoch Childrens Research Institute
                                                                                  Is high-school screening for hereditary screening for haemochromatosis acceptable and fea
496730   Dr Marnie J Wood       Scholarship                                       Clinical                   Clinical the Progression to Institute Progression to Cirrhosis in He
                                                                                                                               Queensland Cirrhosis in Hemochromatosis
                                                         Medical Postgraduate Scholarship and Genetic Modifiers inand Genetic Modifiers in the of Medical Research
508085   Prof Sharad Kumar NHMRC Project Grants          Standard Project Grant                              Study adaptors for theUniversity of cellubiquitin ligases disease
                                                                                                                                       Nedd4 family of physiology and
                                                                                  Roles of Ndfip1 and Ndfip2 as of novel regulatory proteins inAdelaide
509174   Dr Lyle C Gurrin       NHMRC Project Grants     Standard Project Grant                              Treatment effectiveness the prevention of hereditary haemochrom
                                                                                                                                      University of Melbourne
                                                                                  Early versus delayed therapeutic venesection forfor hereditary haemochromatosis
513761   Prof John K Olynyk     NHMRC Career Awards      Practitioner Fellowship  Practitioner Fellowship Practitioner FellowshipUniversity of Western Australia
519739   Dr Richard J Clark     Career Development AwardsBiomedical CDA                                      Effective peptide drugs
                                                                                  Development of effective peptide-based drugs University of Queensland
546452   A/Pr Martin Delatycki NHMRC Career Awards       Practitioner Fellowship                             Uncoupled           Murdoch Childrens Research Institute
                                                                                  Uncoupled Research Fellowship Research Fellowship
552409   A/Pr Grant A Ramm NHMRC Career Awards           NHMRC Research Fellowship                           Uncoupled         Queensland Institute of Medical Research
                                                                                  Uncoupled Research Fellowship Research Fellowship
552412   Dr Daniel F Wallace NHMRC Project Grants                                 Non-HFE haemochromatosis in Australia: natural history and molecularResearch
                                                         Priming Grant (New Investigator)                                      Queensland Institute of Medical characterisation
                                                                                                             Non-HFE haemochromatosis
552430   Prof Gregory J AndersonNHMRC Project Grants     Standard Project Grant                              Iron metabolism and consequences of iron supplementation during
                                                                                                                               Queensland Institute of
                                                                                  Mechanisms of intestinal iron absorption in the perinatal period Medical Research
566555   A/Pr Graham Baldwin NHMRC Project Grant         Standard Project Grant                              Gastrin, Iron            University of
                                                                                  Gastrin, Iron and Colorectal Cancer and Colorectal CancerMelbourne
570844   Dr Rachel Codd         NHMRC Project Grants                              Affinity-based profiling of bacterial Fe(III)-siderophore receptors: design strategies for strate
                                                         Priming Grant (New Investigator)                                                 University of Sydney
                                                                                                             Understanding iron-uptake mechanisms in bacteria to inform antib
572601   A/Pr Deborah Trinder NHMRC Project Grants       Standard Project Grant                              Liver iron transport haemochromatosis
                                                                                                                                    University of Western Australia
                                                                                  Regulation of liver iron loading in hereditaryin hereditary haemochromatosis
613643                          NHMRC
         A/Pr V. Nathan Subramaniam Project Grant        Standard Project Grant                              The Role of Matriptase-2 and Hemojuvelin ofHEMOJUVELIN,
                                                                                                                                        MATRIPTASE-2 AND Medical Research
                                                                                  EXAMINING THE RELATIONSHIP BETWEENQueensland Institutein Iron Metabolism TW
613688   Prof Gregory J AndersonNHMRC Project Grant      Standard Project Grant                              Anaemia and iron homeostasis.
                                                                                                                                      Queensland
                                                                                  Red cell disorders and the regulation of iron homeostasis Institute of Medical Research
613689   Prof Gregory J AndersonNHMRC Project Grant      Standard Project Grant                              Oxidant stress in iron loading diseases
                                                                                                                                      Queensland Institute of Medical Research
                                                                                  Assessment of oxidant stress and mitochondrial dysfunction in young adults with iron loadi
628697   Dr Lyle C Gurrin       NHMRC Project Grant      Standard Project Grant                              Risk iron overload-related disease Melbourne
                                                                                                                                      University of in a disease
                                                                                  Environmental risk factors forfactors for hereditary iron-overload cohort study of hereditary
    App    Start
State            2000-01 2001-02 2002-03    2003-04    2004-05    2005-06   2006-07   2007-08   2008-09   2009-10   2010-11
    Year   Year
NSW 1999   2000 $52,526 $55,004 $60,044      $64,105    $32,395
WA  1999   2000 $117,098 $83,154 $44,364
QLD 2000   2001 $14,415 $27,539 $13,240
NSW 2001   2002           $47,665 $95,330    $95,330    $47,665
QLD   2001   2002   $42,830 $85,660     $85,660    $42,830
WA    2001   2002   $31,500 $64,425     $66,525    $67,950    $69,375    $35,025
WA    2001   2002   $32,665 $65,330     $65,330    $32,665
WA    2001   2002   $57,720 $115,440   $112,885    $55,165
WA    2001   2002   $10,410 $19,459     $19,490                 $206          $0
VIC   2002   2003           $167,650   $338,138   $254,998    $89,260    $18,750
WA    2002   2003            $66,625   $169,875   $169,875    $66,625
WA    2002   2003            $79,125   $158,250   $158,250    $79,125
QLD   2003   2004                       $50,625   $102,375   $104,500    $79,625
QLD   2004   2005                                 $308,976   $637,547   $650,344   $643,546   $703,103   $341,803
NSW   2004   2005                                  $75,750   $151,500   $303,000    $75,750
VIC   2005   2006                                             $24,750    $49,875    $50,750    $90,344    $59,065      $177
QLD   2005   2006                                             $92,750   $179,913   $176,137    $88,974
WA    2005   2006                                             $96,625   $195,288   $199,387   $100,724
WA    2005   2006                                             $16,300    $14,300         $0        $16
QLD   2006   2007                                                        $59,500   $120,250   $122,625   $124,926   $126,101
QLD   2006   2007                                                                  $136,750    $93,375    $95,145    $96,040
QLD   2006   2007                                                        $86,125   $174,036   $177,717    $89,806
QLD   2006   2007                                                        $72,338   $146,166   $149,261    $75,432
VIC   2007   2008                                                                  $100,350   $200,282   $201,762   $162,905
QLD   2007   2008                                                                   $17,127    $17,439    $20,333
SA    2007   2008                                                                  $102,025   $221,932   $226,173   $106,266
VIC   2007   2008                                                                   $48,453    $98,006    $49,554
WA    2007   2008                                                                   $41,213    $83,300    $84,974    $85,774
QLD   2007   2008                                                                             $139,625    $95,145    $96,040
VIC   2008   2009                                                                              $50,488   $101,934   $102,893
QLD   2008   2009                                                                              $56,000   $113,064   $114,128
QLD   2008   2009                                                                              $48,425    $89,974    $41,549
QLD   2008   2009                                                                              $86,200   $174,037   $175,674
VIC   2008   2009                                                                               66038    $133,329   $134,583
NSW   2008   2009                                                                              $48,425    $92,573    $88,296
WA    2008   2009                                                                             $108,500   $219,061   $221,122
QLD   2009   2010                                                                                         $87,379   $174,757
QLD   2009   2010                                                                                         $99,097   $198,194
QLD   2009   2010                                                                                         $98,588   $197,175
VIC   2009   2010                                                                                         $45,473    $75,921
$184,039 $388,487 $876,692 $1,226,213 $1,348,894 $1,428,563 $1,744,083 $2,031,940 $2,750,799 $2,718,627 $2,197,595
   3        9        12        11         12         12         12         14         22         23         18
                                         Broad Research        Field Of     Research Research Research Research Research Health                 Health
2011-12   2012-13   2013-14   Total
                                                Area          Research         KW 1        KW 2        KW 3      KW 4       KW 5       KW 1      KW 2
                              $264,074   Public Health                      ATTITUDES
                                                            Health Counselling                      HAEMOCHROMATOSIS
                                                                                        GENETIC TESTING
                              $244,616   Basic Science      Hepatology                  Hepatocytes and Kupffer Cells
                                                                                                              Iron Metabolism
                                                                            Haemochromatosis Intestinal Absorption Liver Disease              Iron Overload
                                                                                                                                    Haemochromatosis
                               $55,194                      Medical and     Fibrosis    Iron absorption classified disease
                                                                                                    Lipid     Liver
                                         Clinical Medicine and Science Health Sciences not elsewhere peroxidation       Liver transplantation
                              $285,990   Basic Science                                    ataxia    iron      neurodegenerative diseaselevels neurological disease
                                                            Cell Physiology Friedreich'siron chelators metabolism                   iron
                                $256,980                       Gastroenterology and Hepatology
                                            Clinical Medicine and Science                    Iron absorption in cholestatic and hepatocellular cirrhosisLiver
                                                                                                                                              Cirrhosis
                                                                               Hepatic Ferrokinetics Pathophysiology of iron overload in liver cirrhosis disease
                                $334,800    Basic Science      Hepatology                    Haemochromatosis Liver
                                                                               Chelation therapy         Iron metabolism          Liver cancer
                                $195,990    Basic Science      Gastroenterology              Iron transport                       molecular Anaemia Haemochromatosis
                                                                               Intestinal absorption Physiology haemochromatosis mechanisms
                                $341,210                       Gastroenterology and Hepatology
                                            Clinical Medicine and Science      cirrhosis haemochromatosisiron         liver                   haemochromatosis
                                                                                                                                                           iron levels
                                                                                                                                  magnetic resonance imaging
                                  $49,565   Basic Science      Gastroenterology              Hereditary Iron transport
                                                                               HFE knockout mouse haemochromatosis
                                $868,796    Public Health                                    molecular epidemiology
                                                               Epidemiology hereditary haemochromatosis  risk factors                         epidemiology genetic susceptibility
                                $473,000                       Mental Health Genetic polymorphisms
                                            Clinical Medicine and Science                                Iron                     Neurocognitive
                                                                                                                                              Epidemiology
                                                                                             Haemochromatosis Molecular epidemiology assessment            Gerontology
                                $474,750    Basic Science                      Haemochromatosis Iron metabolism
                                                                                             Instestine
                                                               Gastroenterology and Hepatology                        Liver                                Iron overload
                                                                                                                                              Hereditary haemochromatosis
                                $337,125                       Gastroenterology
                                            Clinical Medicine and Science                    intesinal iron
                                                                               haemochromatosis absorption trace element metabolism
                               $3,285,319                      Hepatology
                                            Clinical Medicine and Science                    Hepatic     Iron         Iron
                                                                               Haemochromatosis fibrosis absorption overload      Regulation of iron metabolism
                                $606,000    Basic Science                      haem metabolism
                                                               Therapies and Therapeutic iron Technology neurodegenerative disease reactions
                                                                                                                      oxidative stress
                                                                                                                                  redox                      ataxia
                                                                                                                                              Friedreich'sataxia
                                $274,961                       Gastroenterology
                                            Clinical Medicine and Science                    hepatocytes
                                                                               haemochromotosis          liver cell stem cell transplantation
                                $537,774    Basic Science      Gastroenterologyhaem                      iron                     physiology haemochromatosis
                                                                                             intestinal absorption nutrient transport                      iron deficiency
                                $592,024    Basic Science                      haemochromatosis
                                                                                             intestine iron metabolism
                                                               Gastroenterology and Hepatology                        liver                                inherited disorders
                                                                                                                                              hereditary haemochromatosis
                                  $30,616                      Gastroenterology
                                            Clinical Medicine and Science                    hereditary haemochromatosisliver disease
                                                                               Coeliac disease           nonalcoholic fatty
 $63,051                        $616,453                       Gastroenterology
                                            Clinical Medicine and Science                    Haematology
                                                                               Gastroenterology                       Inherited Iron metabolism
                                                                                                         Haemochromatosis metabolic diseases
 $48,020                        $469,330    Basic Science                      B             Digestive System
                                                               Medical Genetics lood Disorders
                                $527,684                       Hepatology
                                            Clinical Medicine and Science                    hepatic
                                                                               ductular reaction fibrosishepatic progenitor cells                          fatty liver
                                                                                                                                              chronic liver disease disease
                                $443,197    Basic Science                      Drug delivery
                                                               Therapies and Therapeutic haemochromatosis drug design peptides
                                                                                              Technology rational     regulatory                           new approaches to drug desig
                                                                                                                                              haemochromatosis
 $61,076                        $726,375                       Preventive Medicine
                                            Preventative Medicine              Adolescents enetic screening
                                                                                             G                        School health promotion
                                                                                                         Preventative Medicine                             Haemochromatosis
                                                                                                                                              Genetic screening
                                  $54,899                      Gastroenterology and Hepatology epidemiology pathophysiology
                                            Clinical Medicine and Science      SNP           clinical    genetic polymorphismspolymerase chain reaction (PCR)
                                $656,396    Basic Science                      Nedd4 family ofdeath- apoptosis protein-protein interaction
                                                                                             cell ubiquitin ligases
                                                                                                         iron
                                                               Protein Targeting and Signal Transduction transport                                         disease mechanisms
                                                                                                                                  ubiquitin biochemistry and molecular biology
                                $196,013    Public Health      Epidemiology Cohort Studies               Haemochromatosis Statistics                       Genetic Screening
                                                                                             Genetic Predisposition Preventative Medicine Genetic Predisposition To Disease
 $85,774 $42,887                $423,922    Clinical Medicine and Science
                                                               Gastroenterology physiology
                                                                               Cell                      Gastroenterology,Gene expression
                                                                                             Colorectal cancer                    haemochromatosis,
                                                                                                                      Oncology, Hepatocarcinogenesis
 $48,020                        $378,830    Basic Science                      antibiotics chronic Peptides
                                                                                                         hemochromatosis
                                                               Medical Biochemistry: Proteins andpain and analgesia
$102,893 $102,893    $51,447    $512,548                       Medical Genetics linical trial, Genetic screening, Preventative Pharmacological intervention, Genetic screening
                                            Clinical Medicine and Science      C                                      Incurable progressive neurological disease
                                                                                             Friedreich's ataxia, Haemochromatosis
$114,128 $114,128    $57,064    $568,512                       Hepatology
                                            Clinical Medicine and Science      Cystic Fibrosis, Hepatic stellatefibrosis, Bile acids Cholestatic liver disease, Biliary Atresia
                                                                                             Cytokines and chemokines metab
                                                                                                         Hepatic cell, Iron fibrosis,
                                                                                                                      Hepatic     Hereditary haemochromatosis,
                                $179,948    Basic Science                      genetics haemochromatosis
                                                               Genetics not elsewhere classified         iron metabolism
                                                                                                                      liver                   haemochromatosis
                                                                                                                                  molecular basis          hyperferritinaemia
 $87,837                        $523,748    Basic Science                      intestinal absorption iron supplementation pregnancy iron deficiency overload
                                                                                             iron
                                                               Gastroenterology and Hepatology                        neonate                              iron
 $67,292                        $401,242    Basic Science      Gastroenterologycolorectal cancer
                                                                                             gastrin     iron                                              gastroenterology
                                                                                                                                              colorectal cancer (CRC)
 $44,148                        $273,442    Basic Science      Medical Biochemistry: Proteins and Peptides
                                                                               Affinity-based proteindevelopmentFe(III)-siderophore cell-surface receptor proteins bacteria
                                                                                             Antibiotic profiling
                                                                                                         Compounds to treat iron-overload Controlling Development in biofilms
                                                                                                                                  Siderophores and Fe(III) acquisition of antibiotics
                                                                                                                                               disease the formation
$110,561                        $659,244    Basic Science      Hepatology      Hereditary haemochromatosis
                                                                                             inflammation metabolism
                                                                                                         iron         liver                   alcoholic liver diseasehaemochomatosis
                                                                                                                                  oxidative stress         hereditary
$174,757   $87,379              $524,272    Basic Science      Gastroenterology and Hepatology
                                                                               haemochromatosis
                                                                                             iron metabolism
                                                                                                         liver                    proteases anaemia blood disorders
                                                                                                                      molecular mechanisms
$198,194   $99,097              $594,582    Basic Science      Haemotology haemolytic hepcidin iron homeostasis
                                                                                             anaemia                              macrophage iron metabolism
                                                                                                                      iron kinetics                        anaemia
                                                                                                                                              haemolytic hereditary spherocytosis
$197,175   $98,588              $591,526    Clinical Medicine and Science
                                                               Gastroenterology and Hepatology fibrosis overload diseasesoxidative stress
                                                                               haemochromatosis
                                                                                             hepatic     iron         mitochondria                         iron overload diseases
                                                                                                                                              haemochromatosis
 $30,449                        $151,843    Public Health      Epidemiology Cohort Studies               Haemochromatosis Statistics                       Genetic Predisposition To Dis
                                                                                             Genetic Predisposition Preventative Medicine Environmental modifiers
$1,433,375 $544,972 $108,511 $18,982,790
    15        6        2
 Health        Health   Health    Application
                                               Unit Status
 KW 3          KW 4     KW 5        Status
                                              Payments
                                 Payments can be made can be made
Liver Disease                                 Payments
                                 Payments can be made can be made
                                              Payments
                                 Payments can be made can be made
therapeutics                                  Payments
                                 Payments can be made can be made
              Liver transplantation                                Payments
                                                    Payments can be made can be made
                                                                   Payments
                                                    Payments can be made can be made
                                        Iron
               Intestinal Iron deficiency overload                 Payments
                                                    Payments can be made can be made
                            iron        thalassaemia               Payments
               iron overload storage disorder Payments can be made can be made
                                                    Terminated     Terminated
                            risk
               iron overload factors                               Payments
                                                    Payments can be made can be made
                                        Mental health
                                                    Payments can Payments
               Iron levels Memory related disordersand ageing be made can be made
               Liver disease                                       Payments
                                                    Payments can be made can be made
                                                    Terminated     Terminated
                                                                   Payments
                                                    Payments can be made can be made
                            neurological disease Payments can be made can be made
               neurodegenerative diseasetherapeutics               Payments
                                                                   Payments
                                                    Payments can be made can be made
               iron overloadnutrition                              Payments
                                                    Payments can be made can be made
                            liver
               iron overload disease                               Payments
                                                    Payments can be made can be made
                                                                   Payments
                                                    Payments can be made can be made
                                                                   Payments
                                                    Payments can be made can be made
                                                                   Payments
                                                    Payments can be made can be made
                            hepatic     hepatitis C Payments can be made can be made
               hemochromatosis insulin resistance                  Payments
               therapeutics                                        Payments
                                                    Payments can be made can be made
                            Preventive screening Payments can be made can be made
               Health promoting schools Young people               Payments
                                                                   Payments
                                                    Payments can be made can be made
                            iron deficiency
               haemochromatosis                     Payments       Payments
                                        traumatic brain injury can be made can be made
                            Preventive Medicine Payments
                                        Treatment                  Payments
               Hereditary Haemochromatosis Efficacy can be made can be made
                                                                   Payments
                                                    Payments can be made can be made
                                                                   Payments
                                                    Payments can be made can be made
 ervention, Genetic screening                                      Payments
                                                    Payments can be made can be made
hromatosis, Biliary Atresia                                        Payments
                                                    Payments can be made can be made
               iron overloadliver                                  Payments
                                                    Payments can be made can be made
                                                                   Payments
               neonate nutrition pregnancy Payments can be made can be made
               gastrointestinal tumorigenesis                      Payments
                                                    Payments can be made can be made
                                                    Payments       Payments
               Iron-overload disease and beta-thalassemia can be made can be made
                            liver
               iron overload disease                               Payments
                                                    Payments can be made can be made
                            iron levels liver disease ccepted
               haemochromatosis                     A              Payments can be made
               iron overloadthalassaemia            Accepted       Payments can be made
               liver diseasethalassaemia            Accepted       Accepted
                            Hereditary Haemochromatosis can be made can be made
               Genetic Screening                    Payments
                                        Preventive Medicine        Payments

				
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