Cytology Weekly Cases

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					Week of March 30, 2009
17 year old female. Conventional pap
A. Endocervical adenocarcinoma in situ
B. Benign endometrial cells
C. Viral changes consistent with Herpes
D. Alternaria
E. Trichimonas                            1
17 year old female. Conventional pap
C. Viral changes consistent with Herpes
   This picture is slightly out of focus;
    however, you can still see the molding
    and margination of the nuclei c/w
    herpes                                   1
69 year old male. FNA of Lung
A. Granuloma
B. Non-small cell carcinoma
C. Small cell carcinoma
D. Reactive bronchial cells
E. Lymphoma




                                2
69 year old male. FNA of Lung
B. Non-small cell carcinoma – The
    cluster is cohesive with large
    pleomorphic cells. The cells
    are overlapping and
    disorganized.




                                     2
57 year old male. Urine cytology
A. Polyoma virus
B. Reactive urothelial cells
C. High grade TCC
D. Metastatic prostate carcinoma
E. This picture is horrible…I can’t
    tell.




                                 3
57 year old male. Urine cytology
C. High grade TCC -- Though this
    picture is horrible (much like the
    pictures on the test), you can tell
    this is high grade TCC. The
    cells are enlarged (compared to
    the polys) with irregular nuclear
    membranes, eccentric nuclei
    and dark/irregularly distributed
    chromatin.




                                   3
67 year old male. History of prostate carcinoma
    and squamous cell carcinoma of the lung. Now
    presents with bone pain. FNA of bone lesion
A. Positive for tumor - Adenocarcinoma
B. Positive for tumor - SCC
C. Plasma cell neoplasm
D. Positive for tumor – Lymphoma
E. Positive for tumor - melanoma




Diff Quick                                     Pap   4
67 year old male. History of prostate carcinoma
    and squamous cell carcinoma of the lung. Now
    presents with bone pain. FNA of bone lesion
A. Positive for tumor – Adenocarcinoma
    The cells are cohesive with vague formation of
    acinar structures (seen in DQ). The monomorphic
    appearance of the cells along with the prominent
    nuclei favors prostate adenocarcinoma. Melanoma
    is in the differential; however, melanoma cells are
    usually more discohesive. Immunostains can
    always be done to help with the diagnosis.




Diff Quick                                            Pap   4
34 year old female. Thin Prep Pap
A. LSIL
B. Squamous metaplasia
C. Benign endocervical cells
D. HSIL
E. AIS                              5
34 year old female. Thin Prep Pap
D. HSIL                             5
60 year old male. BAL
A. Aspergillus
B. Blastomycosis
C. PCP
D. A and B
E. A and C              6
60 year old male. BAL
E. A and C – This is a case of Aspergillus
   and PCP together.                         6
      51 year old female with extensive
          bilateral lung infiltrates. A BAL
          shows numerous amorphous
          globules as seen here. What
          stain should be ordered to
          confirm the diagnosis?
      A.   Silver stain (GMS)
      B.   PAS
      C.   Iron stain
      D.   Oil Red O
      E.   Reticulin




PAP                                    7
                 51 year old female with extensive
                     bilateral lung infiltrates. A BAL
                     shows numerous amorphous
                     globules as seen here. What
                     stain should be ordered to
                     confirm the diagnosis?
                 B. PAS – PAS will confirm the
                    diagnosis of Pulmonary
                    Alveolar Proteinosis.




Surgical   PAS                                    7
41 year old female with newly
   developed breast mass.
   Breast FNA
A. Positive for breast carcinoma
B. Phyllodes tumor
C. Fibroadenoma
D. Consistent with breast cyst
E. Reactive ductal cells




                                   8
41 year old female with newly
   developed breast mass.
   Breast FNA
C. Fibroadenoma




                                8
29 year old female.
   ThinPrep pap
A. Reactive
B. Squamous metaplasia
C. ASC-US
D. LSIL
E. HSIL                  9
29 year old female.
   ThinPrep pap
D. LSIL               9

				
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