From Wikipedia, the free encyclopedia BOC (gene)
BOC (gene)
Boc homolog (mouse) References
[1] ^ Kang JS, Mulieri PJ, Hu Y, Taliana L, Krauss RS
(Jan 2002). "BOC, an Ig superfamily member,
associates with CDO to positively regulate
myogenic differentiation". EMBO J 21 (1-2): 114–24.
doi:10.1093/emboj/21.1.114. PMC 125805.
PMID 11782431.
http://www.pubmedcentral.nih.gov/
PDB rendering based on 1x4y.
articlerender.fcgi?tool=pmcentrez&artid=125805.
[2] ^ "Entrez Gene: BOC Boc homolog (mouse)".
Identifiers http://www.ncbi.nlm.nih.gov/sites/
Symbols BOC; entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=91653.
External OMIM: 608708 MGI: 2151153
IDs HomoloGene: 32819 GeneCards: BOC Gene Further reading
• Bonaldo MF, Lennon G, Soares MB (1997).
Orthologs
"Normalization and subtraction: two approaches to
Species Human Mouse facilitate gene discovery.". Genome Res. 6 (9): 791–806.
doi:10.1101/gr.6.9.791. PMID 8889548.
Entrez 91653 117606
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
Ensembl ENSG00000144857 ENSMUSG00000022687 "Generation and initial analysis of more than 15,000
UniProt Q9BWV1 Q6AZB0 full-length human and mouse cDNA sequences.".
Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
RefSeq NM_033254 NM_172506.2 doi:10.1073/pnas.242603899. PMC 139241.
(mRNA)
PMID 12477932.
RefSeq NP_150279 NP_766094.1 http://www.pubmedcentral.nih.gov/
(protein) articlerender.fcgi?tool=pmcentrez&artid=139241.
Location Chr 3: Chr 16: • Kang JS, Feinleib JL, Knox S, et al. (2003).
(UCSC) 112.93 – 113.01 44.49 – 44.56 Mb "Promyogenic members of the Ig and cadherin
Mb families associate to positively regulate
PubMed [1] [2]
differentiation.". Proc. Natl. Acad. Sci. U.S.A. 100 (7):
search 3989–94. doi:10.1073/pnas.0736565100. PMC 153035.
PMID 12634428.
Brother of CDO is a protein that in humans is encoded by http://www.pubmedcentral.nih.gov/
the BOC gene.[1][2] articlerender.fcgi?tool=pmcentrez&artid=153035.
CDON (MIM 608707) and BOC are cell surface recep- • Wegorzewska M, Krauss RS, Kang JS (2003).
tors of the immunoglobulin (Ig)/fibronectin type III "Overexpression of the immunoglobulin superfamily
(FNIII; see MIM 135600) repeat family involved in myo- members CDO and BOC enhances differentiation of
genic differentiation. CDON and BOC are coexpressed the human rhabdomyosarcoma cell line RD.". Mol.
during development, form complexes with each other Carcinog. 37 (1): 1–4. doi:10.1002/mc.10121.
in a cis fashion, and are related to each other in their PMID 12720294.
ectodomains, but each has a unique long cytoplasmic • Clark HF, Gurney AL, Abaya E, et al. (2003). "The
tail.[supplied by OMIM][2] secreted protein discovery initiative (SPDI), a large-
scale effort to identify novel human secreted and
transmembrane proteins: a bioinformatics
Interactions assessment.". Genome Res. 13 (10): 2265–70.
BOC (gene) has been shown to interact with CDON.[1] doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
http://www.pubmedcentral.nih.gov/
articlerender.fcgi?tool=pmcentrez&artid=403697.
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From Wikipedia, the free encyclopedia BOC (gene)
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete http://www.pubmedcentral.nih.gov/
sequencing and characterization of 21,243 full- articlerender.fcgi?tool=pmcentrez&artid=2172498.
length human cDNAs.". Nat. Genet. 36 (1): 40–5. • Tenzen T, Allen BL, Cole F, et al. (2006). "The cell
doi:10.1038/ng1285. PMID 14702039. surface membrane proteins Cdo and Boc are
• Kang JS, Yi MJ, Zhang W, et al. (2004). "Netrins and components and targets of the Hedgehog signaling
neogenin promote myotube formation.". J. Cell Biol. pathway and feedback network in mice.". Dev. Cell 10
167 (3): 493–504. doi:10.1083/jcb.200405039. (5): 647–56. doi:10.1016/j.devcel.2006.04.004.
PMC 2172498. PMID 15520228. PMID 16647304.
Retrieved from "http://en.wikipedia.org/w/index.php?title=BOC_(gene)&oldid=418422055"
Categories:
• Human proteins
• Chromosome 3 gene stubs
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