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Syllabus_CBE_Sem 3-8


                                     (B. TECH)


   MAY - 2005

   (Deemed University)
                              JALANDHAR – 144011

Phone: 0181-2690301, 02 (Ext. 213)    Fax: 0181-2690932   Website:

                  To build a rich intellectual potential
                  embedded          with      inter-disciplinary
                  knowledge, human values and professional
                  ethics among the youth, aspirant of
                  becoming engineers and technologists, so
                  that they contribute to society and create a
                  niche for a successful career.


                  To become a leading and unique institution of
                  higher     learning,    offering     state-of-the-art
                  education, research and training in engineering
DEPARTMENT OF     and technology to students who are able and
                  eager to become change agents for the
                  industrial and economic progress of the nation.
BIO ENGINEERING   To nurture and sustain an academic ambience
                  conducive to the development and growth
                  committed      professionals     for     sustainable
                  development of the nation and to accomplish its
                  integration into the global economy.

                                   QUALITY POLICY

                         Develop technical human resource
                          of excellence suitable for global
                         Ensure good quality academic and
                          industrial research programmes in
                          different areas of engineering and
                         Generate industry-institute synergy
                          for shaping technical education to
                          meet the requirement of industry.
With upgradation of Regional Engineering College Jalandhar into National Institute of Technology
Jalandhar (Deemed University), the academic programmes are to be regulated in accordance with the
stipulations made in National Institute of Technology rules, 2002. Accordingly the institute requires to
restructure academic programmes around the credit system in which Mark System of evaluation is
replaced by Letter Grade System and Year wise passing makes way for course wise passing.

We have tried our best to prepare a Model Curriculum and syllabi for four year under graduate
programme in Chemical and Bio Engineering. The exercise was handicapped with the following

i)      It is interdisciplinary in character involving considerable inputs from other disciplines.
ii)     It depends on advances in science, technology and materials
iii)    Its differential status at the National and International level

It is really challenging to evolve a common programme for this discipline that meets the need of
national and international industries and research establishments. However, with the rich experience
of successful experimentation with above idea for over forty years, the task of development of a model
curriculum could be possible.

The suggested curriculum is based on philosophy presented by the Dean (Academic Programmes)
during 5 Senate meeting of the institute held on January 14, 2005. it possesses the following

i)      The suggested curriculum is in conformity with IIT/AICTE norms with emphasis on analysis
        and design of industrial processes required to work in control environment.
ii)     The graduates turned out have to be acceptable by national and international industry and
        academic / research establishments.
iii)    The programme has to be forward looking in context of the rapid changing scenario of
        science and technology which provides a proper balance in teaching of basic sciences, social
        sciences and management, engineering sciences and technical arts, technologies and their
iv)     Core subjects have been selected to cover all those, which are essential in training of CB
v)      The curriculum presents flexibility so that new programmes started with reasonable sources
        can be managed with a scope of further updating as the resource position improves.

The above features have been achieved by offering a number of electives courses both departmental
and open in nature.

I take this opportunity to express my deep appreciation to members of the Senate for their valuable
suggestions and critical comments in finalizing the curriculum and Professor Pramod S Mehta, Ex-
Director, NIT Jalandhar for his initiative and direction. It is hoped that the curriculum complied in form
of the booklet will be of immense help to the students and the faculty in smooth running the under
graduate programme in Chemical and Bio Engineering. I thank all the members of curriculum
committee for their help and cooperation rendered in bringing out this booklet in time.

                                                       (M.K. JHA)
                                                       Dean, Students and Alumni
                                                       Professor and Head
                                                       Department of Chemical and Bio Engineering
                                                       Dr B R Ambedkar National Institute               of
                                                       Jalandhar (Punjab)-144011
Place: Jalandhar

Date: 31.5.2005
                     UNDERGRADUATE PROGRAMME
                             (B. TECH)

                       Chemical and Bio Engineering


 S NO                           CONTENTS                                 PAGE NOS.

  1     Philosophy on Development of UG Curriculum                           1-2

  2     Course Structure (1st to 8th Semester) with details of Credits        3

  3     The Overall Credit Structure                                          4

  4     Course Descriptions

              Courses offered by CB Department                             5-34

              Courses offered by other departments                       35- 45
PHILOSOPHY ON DEVELOPMENT OF UNDER GRADUATE (UG)                                          CURRICULUM          AT


                 With upgradation of Dr B R Ambedkar REC Jalandhar to Dr B R Ambedkar NIT
                  Jalandhar (Deemed University) education being imparted at the Institute requires to be
                  organized around credit-based semester system.
                 There has been a sea-change in objectives, approaches and teaching technology in
                  engineering education during the last couple of years.

         This calls for restructuring of existing academic programme


                 to prepare students for the Technical and analytical skills enabling them to have potential
                  employment in industry, education, research and management.
                 to equip the students with an adequate background of Basic Science, Engineering
                  Science and Arts, Humanities, Social Sciences and Management to enable them to play
                  an effective role of an engineer for benefits of society.


     To realize the above objectives of UG-programmes, curriculum frame work should exhibit the following salient

                 Undergraduate-curriculum should be a broad based
                 Science based engineering education, which enables students to use basic sciences into
                  engineering practice/programmes
                 Should involve continuous evaluation to avoid rote learning and semester end
                 Curriculum should allow varying weightages to various categories of courses
                 Should provide flexibilities in choice of Electives – Departmental and Non-departmental
                 A dynamic regulatory and reviewing process is required to ensure that the proposed
                  curriculum is current.


     To ensure the above enumerated salient features of UG-programmes, the following major recommendations
     were given by Curriculum Core Committee, which were taken as Requirements and guidelines for the B.Tech
     programme at NIT Jalandhar:

         R1      The duration of UG-degree course should be limited to 4 years / 8-semesters each of a
                 minimum of 70-working days.        16-weeks will ordinarily be the duration of

         R2      The first two semesters should be common to all branches of engineering

         R3      Teaching should be reckoned in terms of contact hours. Norms chosen for contact hours
                 and credit correspondence are the same as being observed in IITs i.e. 100% weightage
                 to L and T & 50% weightage to Practical / Lab – contact hours.

         R4      Number of credits required to qualify for                        =    200
                 B.Tech degree should not exceed

         R5      Max / Min number of credits required in any semester            =     30/15

         R6      Total credits divided between various components of             =     3:2
               L,T and P-credits have the ratio :     L : (T+P)

        R7     Max / Min – contact hours for instructions / week              =    34/24

        R8     Max number of years allowed for completing degree-             =    06

        R9     Distribution of credits among various categories of courses

                       HSS and Management                                    :    12 Credits
                       Basic Science (BS)                                    :    32 Credits
                       Engineering Sciences & Arts                           :    36 Credits
                       Professional / Departmental                           :    106* Credits
                       Electives (including Emerging Technology)             :    14 Credits

                * Departmental credits also include 10-credits for Project and 8-credits for Industrial


        R10    Provision for Non-credit courses (Audit courses) should be made in the last 2-years of

        R11    The Major Project should be spread over the last 2-semesters – Phase-I and Phase-II
               with appropriate distribution of credits (8-12 credits).

        R12    Basic Courses should be planned to be taught in large class environment. Tutorial /
               practical Group size should not exceed 20.

        R13    For Laboratory practice a bank of experiments should be prepared with at least 100%
               more than those performed during a semester. Some experiments especially in higher
               semesters shouldl be open-ended – be performed without the help of technician.
         R14   A number of Elective courses (5-6 electives) should be offered starting from the 4
               semester to make the curriculum flexible and the core subjects be adjusted accordingly.
               Numbering scheme for electives should depend on the sequence of semester in which

        R15    Identification of common courses to more than one coherent departments should be
               done for ensuring economic use of faculty and infrastructural facilities in the Institute.

        R16    Participation by persons from industry should be encouraged in teaching courses,
               supervision and evaluation of Industrial Training and Project works.

        R17    Students should be required to attend at least 75% of the scheduled L, T and practical

               * The percentage of attendance calculated up to last day of instructions will reflect into a
               Code-number or Letter in the Grade Sheets.

        R18    Students must undergo Industrial Training at least for 90-100 days. In addition, they
               must participate in NSS, NCC, NSO, Literacy Mission etc. as mandatory requirement to
               qualify for B.Tech degree.

The above major recommendations have served as guidelines for all departments offering
UG-programmes for award of B.Tech Degree in NIT Jalandhar. However, marginal variations in above
suggested distribution of credits may be allowed to suit the requirement of the individual programme.

                                                                   (Dr R Jha)
                                                                   Dean, Academic Programmes
                                                                   January 14, 2005
        Course Structure                                                                                          B. Tech in Chemical and Bio Engineering



                                                                                                                                                                                                                                   Contact Hrs

        Sem                                                                                                                                                                                                         L    T    P

          I      MA-101            PH-101            PH-103            IC-101             IC-103             IE-101              IE-103              HM-101            ME-101           CS-101             07       18   0    12     34          28
                 Math-I            Physics           Physics Lab       Electrical Sci     Electrical Sci     Mfg. Processes      Mfg. Processes      Int. to Mgt. &    Thermal          Comp.Software                    4
                 (3 1 0) 4         (3 1 0) 4         (0 0 2) 1         (3 1 0) 4          Lab                (2 0 0) 2           Lab                 Comm.             Science          – Theory & Prc.
                                                                                          (0 0 2) 1                              (0 0 4) 2           (3 0 2) 4         (3 1 0) 4        (1 0 2) 2

          II     MA-102            CH-101            CH-103            EC-101             EC-103             MC-101              MC-103              HM-102            ME-102           ME-104             06       17   0    10     31          26
                 Math-II           Chemistry         Chemistry Lab     Basic              Basic              Mechanics of        Mech. of Solids     Engg Eco &        Engineering      Engineering                      4
                 (3 1 0) 4         (3 1 0) 4         (0 0 2) 1         Electronics        Electronics Lab    Solids & Fluids     & Fluids Lab        Fin. Mgmt.        Graphics         Graphics Lab
                                                                       (3 1 0) 4          (0 0 2) 1          (3 0 0) 3           ((0 0 2) 1          (3 1 0) 4         (2 0 0) 2        (0 0 4) 2

         III     MA-200            CB-201            CB-203            CB-205             CB-207             CB-209              CB-221              CB-223            CB-227                              06       18   0    06     31          28
                 Numerical         Microbiology      Mechanical        Chem. Process      Chemical           Energy              Microbiology        Mechanical        Chemical Tech.                                    7
                 Methods                             Operation         Calculation        Technology         Engineering         Lab.                Operations Lab.   Lab
                 (3 1 0) 4         (3 1 0) 4
                                                     (3 1 0) 4         (3 2 0) 5          (3 1 0) 4          (3 1 0) 4           (0 0 2) 1           (0 0 2) 1         (0 0 2)1

         IV      MA-202            PH-204            CB-202            CB-222             CB-204             CB-206              CB-208              PH-224            CB-224                              06       18   0    10     32          28
                 Optimization      Material          Biochemistry      Biochemistry       Heat Transfer      Chemical Engg.      Chem. Reaction      Material Sc. &    Energy Engg.                                      4
                 Techniques        Science & Engg    (3 0 0) 3         Lab                (3 1 0) 4          Thermodyna.         Engg-I              Engg. Lab         Lab.
                 (3 0 2) 5         (3 1 0) 4                           (0 0 3) 2                             (3 1 0) 4           (3 1 0) 4           (0 0 2) 1         (0 0 3) 2

          V      CB-301            CB-303            CB-305            CB-307             CB-309             CB-321              CB-327              CB-3XX                                                06       16   0    07     27          24
                 Mass Transfer –   Chem. Reaction    Petroleum         Bioprocess         Process Plant      Heat Transfer       Bio process         DE-I                                                                4
                 I                                   Refining Engg.    Engg.              Design I                                                   (3 0 0) 3

                                   Engg. II                                                                  Lab.                Engg. Lab.
                 (3 1 0) 4                           (3 1 0) 4         (3 1 0) 4          (1 0 3) 3
                                   (3 1 0) 4                                                                 (0 0 2) 1           (0 0 2) 1

         VI      CB-302            CB-304            CB-306            CB-3XX             CB-322                                                                                        OC-3XX             05       13   0    04     18          16
                 Mass Transfer –    Process Eco. &   Process Plant     DE-II              Mass Transfer                                                                                 OE-I                             1
                 II                Mngt.             Design II         (3 0 0) 3          Lab.                                                                                          (3 0 0) 3
                 (3 1 0) 4         (3 0 0) 3         (1 0 2) 2                            (0 0 2) 1

       Summer                                                                                          CB-300 Industrial Practical Training (0 0 16) 8                                                                                           08
         VII     CB-401            CB-403            CB-405            CB-423             CB-400             CB-427              CB-4XX                                                 OC-4XX             05       14   01   10     25          20
                 Chemical          Molecular         Industrial        Process            Project (Ph-I)     Colloquium          DE-III                                                 OE-II
                 Process Control   Biology &         Instrumentation   Modeling &         (0 0 4) 2                              (3 0 0) 3                                              (3 0 0) 3
                 (3 1 0) 4         Genetic Engg.     (2 0 0) 2         Sim. Lab                              (0 0 2) 1
                                   (3 0 0) 3                           (0 0 4) 2

        VIII     CB-402            CB-404            CB-422            CB-424             CB-400                                                     CB-4XX                                                03       9    01   20     30          20
                 Industrial        Environmental     Chem. Process     Environmental      Project (Ph-II)                                            DE-IV
                 Biotechnology     Engg. & Saf.      Cont. & Rxn.      Engg. Lab.         (0 0 16) 8                                                 (3 0 0) 3
                 (3 0 0) 3         (3 1 0) 4         Engg. Lab.
                                                                       (0 0 2) 1
                                                     (0 0 2) 1

                                                                                                                                                                                                                                   Total         198

    DE : 4 @ 3C = 12 C                                                          HM : 2 @ 4 = 8C from 2-courses
                                                                                OE : 2 @ 3 = 6 C     DC : 113, BS : 31, EAS : 28
Programme Code: CB
    Bachelor of Technology in Chemical and Bio Engineering
Department of Chemical and Bio Engineering
The overall credit structure                                         IC-302
                                                                                    Advanced Process Control
                                                                                    Transducers and Signal
                                                                     CB-302         Mass Transfer – II            3-1-0      4
 Undergraduate Core (UC)           Undergraduate Elective            CB-303         Chemical Reaction             3-1-0      4
                                            (UE)                                    Engineering – II
  Category         Credits         Category      Credits             CB-304         Process Economics &           3-0-0      3
   HSS&M             08               DE            12                              Management
                                                                     CB-305         Petroleum Refining            3-1-0      4
      BS             31              OE             06
     EAS             28
                                                                     CB-306         Process Plant Design – II     1-0-2      2
     DC              113
                                                                     CB-307         Bioprocess Engineering        3-1-0      4
   TOTAL             180            TOTAL             18             CB-309         Process Plant Design – I      1-0-3      3
 Total Credits = 198                                                 CB-321         Heat Transfer Laboratory      0-0-2      1
                                                                     CB-322         Mass Transfer Laboratory      0-0-2      1
 Humanities, Social Sciences and Management (HSS&M)                  CB-327         Bioprocess Engineering        0-0-2      1
 HM-101    Introduction to Management and 3-0-0                3                    Laboratory
           Communication                                             CB-400         Project (Phase-I & II)        0-0-20     10
 HM-102    Engineering Economics and      3-1-0                4     CB-401         Chemical Process Control      3-1-0      4
           Financial Management                                      CB-402         Industrial Biotechnology      3-0-0      3
 HM-103    Communication Laboratory       0-0-2                1     CB-403         Molecular Biology & Genetic   3-0-0      3
           TOTAL HSS&M                    6-1-2                8                    Engineering
                                                                     CB-404         Environmental Engineering     3-1-0      4
 Basic Sciences (BS)                                                                and Safety
 MA-101    Mathematics-I                     3-1-0             4     CB-405         Industrial Instrumentation    2-0-0      2
 MA-102    Mathematics-II                    3-1-0             4     CB-422         Chemical Process Control &    0-0-2      1
 MA-200    Numerical Methods                 3-1-0             4                    Reaction Engineering
 MA-202    Optimization Techniques           3-0-2             4                    Laboratory
 PH-101    Physics                           3-1-0             4     CB-423         Process Modeling and          0-0-4      2
 PH-103    Physics Laboratory                0-0-2             1                    Simulation Laboratory
 PH-204    Material Science & Engineering    3-1-0             4     CB-424         Environmental Engineering     0-0-2      1
 PH-224    Material Science & Engineering    0-0-2             1                    Laboratory
           Laboratory                                                CB-427         Colloquium                    0-0-2      1
 CH-101    Chemistry                         3-1-0             4                    TOTAL DC                      61-16-69   113
 CH-103    Chemistry Laboratory              0-0-2             1
           TOTAL BS                          21-6-8            31
                                                                    Department Electives (DE)
 Engineering Arts and Sciences (EAS)                                 CB-310        Bioinformatics                 3-0-0      3
 IC-101    Electrical Science                3-1-0             4
 IC-103    Electrical Science Laboratory     0-0-2             1     CB-311         Enzyme Technology             3-0-0      3
 EC-101    Basic Electronics                 3-1-0             4     CB-312         Protein Engineering           3-0-0      3
 EC-103    Basic Electronics Laboratory      0-0-2             1     CB-313         Bio Pharmaceuticals           3-0-0      3
 CS-101    Computer Software – Theory        1-0-2             2     CB-314         Petrochemical Technology      3-0-0      3
           and Practice                                              CB-315         Transport Phenomena           3-0-0      3
 IE-101    Manufacturing Processes           2-0-0             2     CB-410         Immunology                    3-0-0      3
 IE-103    Manufacturing Processes           0-0-4             2     CB-411         Food Biotechnology            3-0-0      3
           Laboratory                                                CB-412         Cell and Tissue Culture       3-0-0      3
 ME-101    Thermal Science                   3-1-0             4     CB-413         Down Stream Processing        3-0-0      3
 ME-102    Engineering Graphics              2-0-0             2     CB-414         Polymer Technology            3-0-0      3
 ME-104    Engineering Graphics              0-0-4             2     CB-415         Plant Utilities               3-0-0      3
           Laboratory                                                CB-416         Natural Gas Engineering       3-0-0      3
 MC-101    Mechanics of Solids and Fluids    3-0-0             3     CB-417         Petroleum Recovery            3-0-0      3
 MC-103    Mechanics of Solids and Fluids    0-0-2             1                    Technology
           TOTAL EAS                         17-3-16           28   Open Electives (OE)
                                                                     OC/CB-332      Energy Technology             3-0-0      3
 Departmental Core (DC)                                              OC/CB-431      Basic Biotechnology           3-0-0      3
  CB-201   Microbiology                      3-1-0         4
  CB-202   Biochemistry                      3-0-0         3
  CB-203   Mechanical Operations             3-1-0         4
  CB-204   Heat Transfer                     3-1-0         4
  CB-205   Chemical Process                  3-2-0         5
  CB-206   Chemical Engineering              3-1-0         4
  CB-207   Chemical Technology               3-1-0         4
  CB-208   Chemical Reaction                 3-1-0         4
           Engineering – I
  CB-209   Energy Engineering                3-1-0         4
  CB-221   Microbiology Laboratory           0-0-2         1
  CB-222   Bio Chemistry Laboratory          0-0-3         2
  CB-223   Mechanical Operations             0-0-2         1
  CB-224   Energy Engineering                0-0-3         2
  CB-227   Chemical Technology               0-0-2         1
  CB-300   Industrial Practical Training     0-0-16        8
  CB-301   Mass Transfer - I                 3-1-0         4
(Courses Offered by CB Department)


S. NO.     COURSE NO.        COURSE TITLE                          PERIODS        CREDITS
                                                              L      T    P/D
1.         CH 101            Chemistry                        3      1    0       4
2.         EC-101            Basic Electronics                3      1    0       4
3.         HM-101            Introduction to Management       3      0    0       3
4.         HM-102            Engineering Economics and        3      1    0       4
                             Financial Management
5.         MA-101/MA-102     Mathematics-I/Mathematics-II     3     1     0       4
6.         MC-101            Mechanics of Solids & Fluids     3     0     0       3
7.         ME-102            Engineering Graphics             2     0     0       2
8.         CH-103            Chemistry                        0     0     2       1
9.         EC-103            Basic Electronics Laboratory     0     0     2       1
10.        MC-103            Mechanics of Solids & Fluids     0     0     2       1
11.        ME-103            Engineering Graphics             0     0     4       2
                             TOTAL                            20    4     10      29
         Drawing practice

                                                                               Contact Hours = 34


S. NO.     COURSE NO.        COURSE TITLE                          PERIODS        CREDITS
                                                              L      T    P/D
1.         HM-101            Introduction to Management and   3      1    0       4
2.         IC-101            Electrical Science               3     1     0       4
3.         IE-101            Manufacturing Processes          2     0     0       2
4.         MA-101/MA-102     Mathematics-I/Mathematics-II     3     1     0       4
5.         ME-101            Thermal Science                  3     1     0       4
6.         PH-101            Physics                          3     1     0       4
7.         CS-103            Computer Software – Theory       1     0     2       2
                             and Practical
8.         HM-103            Communication Laboratory         0     0     2       1
9.         IC-103            Electrical Science Laboratory    0     0     2       1
10.        IE-103            Manufacturing Process 16         0     0     4       2
11.        PH-103            Physics Laboratory               0     0     2       1
                             TOTAL                            18    5     12      29
                                                                               Contact Hours = 35
S      Course   Course Title                       Periods        Contact Credits
No     No                                                         Hours
                                                   L    T    P

1.     MA-200   Numerical Methods                  3    1    0    4       4

2.     CB-201   Microbiology                       3    1    0    4       4

3.     CB-203   Mechanical Operations              3    1    0    4       4

4.     CB-205   Chemical Process Calculations      3    2    0    5       5

5.     CB-207   Chemical Technology                3    1    0    4       4

6.     CB-209   Energy Engineering                 3    1    0    4       4

7.     CB-221   Microbiology Laboratory            0    0    2    2       1

8.     CB-223   Mechanical Operations Laboratory   0    0    2    2       1

9.     CB-227   Chemical Technology Laboratory     0    0    2    2       1

                Total                              18   7    6    31      28

Fourth Semester
S      Course   Course Title                       Periods        Contact Credits
No     No                                                         Hours
                                                   L    T    P

1.     PH 204   Material Science and Engineering   3    1    0    4       4
2.     CB-202                                      3    0    0    3       3
       MA 202   Optimization Techniques
3.                                                 3    0    2    5       4
                Heat Transfer
4.     CB-204                                      3    1    0    4       4
                Chemical Engineering
5.     CB-206                                      3    1    0    4       4
6.     CB-208   Chemical Reaction Engineering –I   3    1    0    4       4

7.     PH 224   Material Science and Engineering   0    0    2    2       1
                Biochemistry Laboratory
8.     CB-222                                      0    0    3    3       2

9.     CB-224   Energy Engineering Laboratory      0    0    3    3       2

                Total                              18   4    10   32      28
Fifth Semester

S    Course      Course Title                        Periods       Contact Credits
No   No                                                            Hours
                                                     L    T    P

1.   CB 301      Mass Transfer –I                    3    1    0   4       4

2    CB 303      Chemical Reaction Engineering - 3        1    0   4       4

3    CB 305      Petroleum Refining Engineering      3    1    0   4       4

4    CB 307      Bioprocess Engineering              3    1    0   4       4

5    CB 309      Process Plant Design – I            1    0    3   4       3

6.   CB 3XX      Elective –I                         3    0    0   3       3

7    CB 321      Heat Transfer Laboratory            0    0    2   2       1

8    CB-327      Bioprocess Engineering Laboratory   0    0    2   2       1

                 Total                               16   4    7   27      24
Sixth Semester

S    Course      Course Title                        Periods       Contact Credits
No   No                                                            Hours
                                                     L    T    P

1    CB 302      Mass Transfer –II                   3    1    0   4       4

2    CB 304      Process    Economics            and 3    0    0   3       3

3    CB 306      Process Plant Design –II            1    0    2   3       2

4    CB 3XX      Elective – II                       3    0    0   3       3

5    OC 3XX      Open Elective – I                   3    0    0   3       3

6    CB 322      Mass Transfer Laboratory            0    0    2   2       1

7.   CB 300      Industrial Practical Training       0    0    0   0       8

                 Total                               13   1    4   18      24
Seventh Semester

S      Course   Course Title                       Periods       Contact Credits
No     No                                                        Hours
                                                   L    T    P

1      CB 401   Chemical Process Control           3    1    0   4       4

2      CB 403   Molecular Biology and Genetic 3         0    0   3       3

3      CB 405   Industrial Instrumentation         2    0    0   2       2

4      CB 4XX   Elective –III                      3    0    0   3       3

5.     OC 4XX   Open Elective –II                  3    0    0   3       3

6      CB 423   Process Modeling and Simulation 0       0    4   4       2

7.     CB 400   Project ( Phase –I)                0    0    4   4       2

8.     CB 427   Colloquium                         0    0    2   2       1

                Total                              14   1    10 25       20

     Eighth Semester

S      Course   Course Title                       Periods       Contact Credits
No     No                                                        Hours
                                                   L    T    P

1      CB 402   Industrial Biotechnology           3    0    0   3       3

2      CB 404   Environmental    Engineering   and 3    1    0   4       4

3      CB 4XX   Elective – IV                      3    0    0   3            3

4.     CB 422   Chemical Process Control and 0          0    2   2       1
                Reaction Engineering Laboratory

5.     CB 424   Environmental           Engineering 0   0    2   2       1

6.     CB 400   Project ( Phase –II)               0    0    16 16       8

                Total                              9    1    24 29       20
List of Electives

   Elective I

   S.No               Course Title               L   T   P   C
   1    CB 311        Enzyme Technology          3   0   0   3
   2    CB 313        Bio Pharmaceuticals        3   0   0   3
   3    CB 315        Transport Phenomena        3   0   0   3

   Elective II

   S.No               Course Title               L   T   P   C
   1    CB 310        Bioinformatics             3   0   0   3
   2    CB 312        Protein Engineering        3   0   0   3
   3    CB 314        Petrochemical              3   0   0   3

   Elective III

   S.No               Course Title               L   T   P   C
   1    CB 411        Food Biotechnology         3   0   0   3
   2    CB 413        Down             Stream    3   0   0   3
   3       CB 415     Plant Utilities            3   0   0   3
   4       CB 417     Petroleum       Recovery   3   0   0   3

   Elective IV

   S.No               Course Title               L   T   P   C
   1       CB 410     Immunology                 3   0   0   3
   2       CB 412     Cell and Tissue Culture    3   0   0   3
   3       CB 414     Polymer Technology         3   0   0   3
   4       CB 416     Natural            Gas     3   0   0   3

   Open Elective I

   S.No               Course Title               L   T   P   C
   1    OC/CB 332     Energy Technology          3   0   0   3

   Open Elective II

   S.No               Course Title               L   T   P   C
   1    OC/CB 431     Basic Biotechnology        3   0   0   3

CB- 201       Microbiology                                                   [ 3 1 0 4 ]

Scope and History of Microbiology: Scope and History of Microbiology, Classification,
Characterization, Identification and Nomenclature of Microorganisms, Microscopy,
Morphological, Structural and Biochemical characteristics of prokaryotes and eukaryotes
(bacteria , yeast, mold, algae, protozoa, actinomycetes)
Cultivation of Microorganisms: Microbiological media, physical conditions required for
Reproduction and Growth of Microorganism: Modes of cell division , growth curve of
microbes, Quantitative measurement of growth.
Methods in Microbiology: Chemical, Physical and Biological methods of selection of
microorganisms , Methods of isolating pure cultures , Maintenance and preservation of pure
cultures , microbial mutation .
Microbial Metabolism: Metabolic pathways and Bioenergetics, Aerobic and Anaerobic
growth, Transport of nutrients across cell membranes
Physical and Chemical Control of Microorganism: Major groups of antimicrobial agents ,
Mode of action and practical applications
Energy Transduction Mechanisms in Microbial Cell : Aerobic and anaerobic respiration,
Microbial photosynthesis, Transduction, Transformation, Conjugation
Microbial Interaction :- Roles of microbes in Nitrogen, Carbon and Sulphur cycle
Application of Microorganism in various Field : - Agriculture, food, environment ,
medicine, public health and industry.
Viruses:      Classification,    morphology     and    composition,  DNA      and     RNA
bacteriophages,Lysogeny and lytic cycle

Books Recommended

1.     Pelczar M J, Chan E C S and Krieg N R “Microbiology,” Mc Graw Hill, New York
2.     Salle A J, “Fundamental Principles of Bacteriology” , Tata McGraw Hill, New Delhi
3.     Stanier R Y, “Text in Microbiology” McMillan Press London (1995)
4.     Davis B D, “Microbiology”, Harper and Row Publications, Hageston (1980)
5.     Casida L E, “Industrial Microbiology”, New Age International Publishers, New Delhi

CB-202        Biochemistry                                                      [3 0 0 3]

Molecular basis of life,tudy of macro molecules
Carbohydrates: Their structure and biological functions, Monosaccharides disaccharides
and polysaccharides Glycoproteins.
Amino Acids and Proteins: Their structure and function,Types of amino acids,Fbrous
proteins and globular proteins, Separation of proteins
Fats and Lipids: Their structure and biological functions, Types of lipids, triacylglycerol,
Waxes, Phospolipids, Sphingolipids, Lipoproteins
Nucleic acid and Nucleotides : DNA, Structure of chromosomes and genes, Replication
and transcription of DNA, RNA Protein synthesis and its regulation, Genetic recombination
and cloning
Vitamins and Harmones: Types, Structure and functions
Photosynthesis: Chlorophylls, Kinds and roles of photosystems, Calvin cycle
Enzymes: Properties and types, Kinetics of enzyme action, Enzyme inhibition,Allosteric
enzymes, Assay of enzymes, Regulation of enzyme activity
Bioenergetics and Metabolism: Metabolism, basic concepts and design, Glycolysis citric
acid cycle oxidative phosphorylation pentose phospate pathway and gluconeogenesis
glycogen and disaccharide metabolism amino acid degradatoon and urea cycle
Biological Membranes: Characteristics of biological membranes components of
membranes types of membranes fluid mosaic model membrane asymmetry

Books Recommended

1.     Stryer L, “Biochemistry” ,W.H.Freeman and Company (1995)
2.     Lehninger, A L “Principles of Biochemistry”, Butterworth Publishers, New York
3.     Conn E E and Stumpf P K “Outlines of Biochemistry” ,John Wiley and Sons, New
       York (1987)
4.     Walsh G , “ Proteins Biochemistry and Biotechnology” John Wiley and sons (2003)
5.     Rastogi,” Biochemistry” , 2nd Edition, Tata Mc Graw Hill (2003).

CB-203         Mechanical Operations                                                   [3 1 0 4 ]

Size Reduction : Particle size and shape, particle mass, size and shape distributions,
measurement and analysis, concept of average diameter ,size reduction , crushing, grinding
and law of grindings.
Screening : Screening equipment ,capacity and effectiveness of screen, effect of mesh size
on capacity of screen.
Settling : Flow around a single particle, drag force and drag coefficient, settling velocity of
particles in a fluid, hindered and free settling of particles, thickening gravity separation
Filtration : Classification of filters, various types of cake filters ,principle of cake filtration
,clarification filters, liquid clarification, centrifugal settling process.
Agitation & Mixing: Agitation of liquids, axial flow impellers, radial flow impellers, velocity
and power consumption of agitated vessels, blending & mixing.
Fluidization : Packed beds, bed porosity, flow though a bed of particles, fluidization &
fluidized bed, conditions for fluidization minimum velocity, types of fluidization.
Solid Handling : Flow of solid by gravity, transport of solids by screw / belt conveyers,
cyclones, bag filters, electrostatic precipitators, particulate collection system.

Books Recommended

1.     Smith J C, Mccabe W L and Harriot P H, “Unit Operations of Chemical Engineering”,
       McGraw Hill (2001).
2.     Bhattacharya B C and Narayanan C M “Mechanical Operation for Chemical
3.     Perry’s, “Handbook of Chemical Engineering”, 7th Ed, McGraw Hill (1997).
4.     Brown G G “Unit Operations” 1st ed. , CBS Publisher (2004)
5.     Richardson and Coulson “Chemical Engineering Vol II”,5 th ed., Butterworth –
       Heinemann (2003).

CB-204         Heat Transfer                                                           [3 1 0 4]

Conduction: Basic law of heat conduction – Fourier’s law, thermal conductivity, its
dependence on temperature, steady state heat conduction through a composite solid and its
electric analogue, steady state heat conduction through cylinders, spheres and variable area
of solids, different insulating materials and their applications for process equipment and
pipelines, Fourier’s law in three dimensions, lumped capacity method of unsteady state
Convection: Convection heat transfer and the concept of heat transfer coefficient, individual
and overall heat transfer coefficient, heat transfer between fluids separated by plane wall,
heat transfer between fluids separated by cylindrical wall (pipes), critical/ optimum insulation
thickness, heat transfer through extended surfaces.
Forced Convection: Over a flat plate, thermal boundary layer, dimensionless groups and
dimensional analysis, Buckingham Pi-theorem, heat transfer correlations- internal and
external flows, laminar and turbulent flows,
Free convection: Heat transfer correlations for free convection, free convection from flat
surfaces, free convection from a cylinder.
Heat Transfer with phase change: Boiling phenomena and analysis of boiling curve,
correlation for nucleate boiling, critical heat flux, condensation phenomena, film
condensation on a vertical surface (Nusselt equation, effect of non-condensable gases, drop
wise condensation.
Radiation: Basic principle of radiation from a surface, blackbody radiation, Planck’s law,
Wein’s displacement law, the Stefan Boltzmann law, Kirchoff’s law, gray body, radiation
exchange between black bodies & gray bodies.
Evaporation: Types of evaporators, single and multiple effect evaporators, capacity and
economy, boiling point elevation.
Books recommended

1.     Geankopolis C J, “Transport Processes and Separation Process Principles”, Prentice
       Hall of India, 4th Edition, Eastern Economy Edition (2004)
2.     Holman J P, “Heat Transfer”, McGraw Hill Book Co. (1992).
3.     Incropera F P and DeWitt D P, “Introduction to Heat Transfer,” 2nd Ed John Wiley
       New York (1996).
4.     Kern D Q, “Process Heat Transfer”, McGraw Hill Book Co. (1997).
5.     Coulson J M and Richardson J F, “Chemical Engineering” Volume 1, Pergamon
       Press (1999).

CB-205         Chemical Process Calculations                                        [3 2 0 5]

Introduction to Chemical Engineering Calculations: Units and dimensions, mole concept,
conventions in methods of analysis and measurement, basis, temperature, pressure, the
chemical equations and stoichiometry, limiting and excess reactant, conversion and yield.
Material Balance: Material balance, program of analysis of material balance problems,
solving material balance problems that do not involve chemical reactions, solving material
balances problems involving chemical reactions, multiple subsystems, recycle, bypass, and
purge calculations.
Gases Vapors, Liquids and Solids: Ideal gas law calculations, real gas relationships,
vapor pressure and liquids, saturation, partial saturation and humidity.
Energy Balances: Concepts and units, calculation of enthalpy changes, application of the
general energy balance without reactions occurring, energy balances that account for
chemical reaction, reversible processes and the mechanical energy balances, heats of
solution and mixing, psychrometric charts and their use.
Books recommended

1.     Himmelblau D M, “Basic Principles and Calculations in Chemical Engineering,”
       Prentice Hall (1998).
2.     Haugen O A, Watson K M and Ragatz R A, “Chemical Process Principles (Part-I):
       Material and Energy Balances”, Asia Publishing House (1995).
3.     Bhatt B I and Vora S M, “ Industrial Stoiciometry”: Tata McGraw Hill Publishing, New
       Delhi (1987).
4.     Reklaitis G V, “Introduction to material and energy balances” Wiley, New York (1983)
5.     Felder R M and Rousseau R W, “Elementary principles of Chemical Processes”
       Wiley, New York 2nd Edition (1986)
CB-206        Chemical Engineering Thermodynamics                               [3 1 0 4]

Review of First ,Second            and Third Law of Thermodynamics : First law of
Thermodynamics , Thermodynamics state and state functions , enthalpy, the steady state
steady flow process, equilibrium, phase rule, reversible processes , Second law of
thermodynamics, Heat engines, Entropy, Entropy changes of an ideal gas,
Third law of thermodynamics.
Volumetric properties of pure fluids :PVT behaviour for an ideal gas, Virial equation of
state, Applications of Virial equations, Cubic equation of state, Generalized correlations,
Acentric factors.
Heat Effects : Sensible Heat Effects , Internal Energy of ideal gases, Latent heat of pure
substances , Standard heat of reaction, formation , combustion, Heat of reaction at higher
temperature, Heat effects of Industrial reactions.
Thermodynamic Properties of fluid: Maxwell relations, Residual properties, Two phase
system, Thermodynamic diagram
Equilibrium and Stability: Criteria of equilibrium, Chemical Potential, Application of
equilibrium criteria, Clausius clapeyon equation.
Phase Equilibria: Fugacity ,Determining of fugacity of pure substances, Fugacity in
mixture, Ideal solution , Excess properties, Liquid phase properties from VLE data, Activity
coefficients, coefficient equations.
Chemical Reaction Equilibria: Reaction ordinate for single & multiple reactions , condition
of equilibrium for a chemical reactions, Standard states and G, Temperature dependence
of the equilibrium constant , Estimation of equilibrium rate constant , Homogeneous gas
phase reactions, Heterogeneous chemical equilibrium.

Books Recommended

1.     Smith J M, Van Ness H C, Abbott M M, “Introduction to Chemical Engineering
       Thermodynamics” , McGraw Hill ( TMH Edition), 6th ed (2003).
2.     Rao Y V C, “ Chemical Engineering Thermodynamics”, First Edition, Universities
       Press (India) Ltd., Hyderabad (1997).
3.     Kyle B G, “Chemical and Process Thermodynamics”, Third Edition, Prentice Hall
       PTR, Upper Saddle River, New Jersy (1999).
4.     Denbigh K G, “Principles of Chemical Equilibrium”, Cambridge University Press, 4th
       ed. (1981).
5.     Keeneth S Pitzer, “Thermodynamics”, McGraw Hill, 3rd ed.

CB- 207       Chemical Technology                                               [3 1 0 4 ]

Soaps & Detergents: Raw materials and Reaction Chemistry, Continuous process for
manufacture of fatty acids, soaps and glycerine, Classification of detergents, Builders and
additives, Manufacture of detergents like alkyl benzene sulphonate ,Sodium alkane
Cane Sugar: Manufacturing equipments and technology, Cane sugar refining. Polymers :
Nomenclature of polymers and their classification, Modes of polymerisation i.e addition,
condensation , step growth and chain growth polymerisation , Methods of polymerisation,
Synthetic fibres: Cellulosic fibres, manufacture of Viscose Rayon , Polyamides; Plastics :
Classification, manufacture of different types of Polyethylene; Rubbers : Natural rubber,
different types of synthetic rubbers, manufacture of styrene- butadiene rubber
Chlor- Alkali Industry: Electrochemistry of brine electrolysis , diaphragm cells, mercury,
cells, membrane cells ,Manufacture of caustic soda , chlorine and hydrochloric acid ,
Manufacture of Soda Ash
Portland Cement: Raw materials, types and properties of cement, manufacture of portland
Sulphuric Acid: Raw materials, Contact process of the manufacture of sulphuric acid and
Fertilizers : Elements required for plant growth, classification of fertilizers,N-P-K Values,
Ammonia based fertilizers, Phosphatic fertilizers, Potash fertilizers

Books Recommended

1.     Dryden C E, “Outlines of Chemical Technology”, East –West Press Pvt. Ltd., New
       Delhi, 2nd Edition (1973 )
2.     Austin G T, “Shreve’s Chemical Process Industries”, McGraw Hill Book Company,
       New Delhi 5th Edition (1986 )
3.     Chemical Engineering Education Development Centre– “Chemical Technology I, II,
       III , IV , Manual of Chemical Technology, Indian Institute of Technology , Madras”.
4.     Shukla S D and Pandey G N, “A text book of Chemical Technology Vol I”, Vikas
       Publishing House Pvt. Ltd., New Delhi
5.     Shukla S D and Pandey G N, “A text book of Chemical Technology Vol lI”, Vikas
       Publishing House Pvt. Ltd., New Delhi

CB-208          Chemical Reaction Engineering - I                             [3 1 0 4]

Introduction: Kinetics of homogeneous chemical and biochemical reactions, single and
multiple reactions, order & molecularity, rate constant, elementary and non elementary
reactions, temperature dependent term of rate equation,
Interpretation of Batch Reactor: Constant volume batch reactor, integral method of
analysis of data, series and parallel reactions, reversible reactions, Variable volume batch
reactor, Differential methods of analysis, Temperature and reactions rate.
Introduction to Reactor Design: Ideal batch reactor, mixed flow reactor, plug flow reactor,
holding and space time, design for single reactions, size comparison (analytical and
graphical method, plug flow reactors in series & parallel, mixed reactor in series , recycle
Design for Multiple Reactions: Reactions in parallel and series in C.S.T.R, reactions in
parallel and series in Plug flow reactor, yield & selectivity.
Temperature and Pressure Effect: General design procedure, optimum temperature
progression, adiabatic operation, non adiabatic operation, semi batch reactors.
Non Catalytic Fluid Solid Reactions: Selection of model, unreacted core model for
spherical particles, diffusion through gas film control, diffusion through ash layer control,
chemical reaction control, Design.

Books Recommended

1.     Levenspiel O, “Chemical Reaction Engineering”, 3rd Ed , John Wiley & Sons,
       Singapore (1999).
2.     Fogler H Scott, “Elements of Chemical Reaction Engineering”, 3rd ed, Prentice Hall
       Inc. (1999).
3.     Smith J M , “Chemical Engineering Kinetics” , McGraw Hill , 3rd ed. (1981).
4.     Hill, C G, “ Chemical Engineering Kinetics and Reactor Design”, John Wiley (1977).
5.     Coulson J M and Richardson J F, “Chemical Engineering Volume 3”, Pergamon
       Press (1999).

CB-209         Energy Engineering                                                      [3 1 0 4 ]

Solid Fuels : Principle Solid Fuels – Coal, origin , composition & classification of coal,
properties of coal , terms used in analysis of coal, classification of Indian coals , petrology of
Coal Preparation : Dry and Wet processes, storage of coal. Coal carbonisation :
mechanism of carbonisation , high temperature and low temperature carbonization
briquetting, gasification of coal, Lurgi process, Winkler process , Kopper –Totzek process ,
liquefaction of solid fuels.
Liquid Fuels: Petroleum and related products,origin, occurrence and reserves, nature of
petroleum crudes, classification and characteristics of petroleum, Refining Unit Process:
Cracking, Thermal Cracking ,Catalytic cracking , Hydrocracking, Reforming Thermal and
Catalytic Reforming, Alkylation, Polymerization Isomerization, petroleum products :naphtha,
motor gasoline, aviation gasoline , kerosene , diesel oil, gas oil , fuel oil , lubricants ,
petroleum waxes,petroleum coke.
Gaseous Fuels: Classification, Wobbe Index natural gas, methane from coal mines,
producer , water, carbureted water gas , coal, blast furnace , refinery gases , LPG.
Combustion: General Principles of combustion, stoichiometry & heat balance calculations,
coal burning equipments, stokers, pulverized fuel burners gas and oil burners, fluidized bed
Alternate Energy Systems: Solar Energy – Photovoltaic cells , solar collectors. Nuclear
energy: nuclear reactions, fuel materials, moderators and structural materials, reactors
,wind energy, tidal energy, geothermal energy .
Furnaces : General classification and description of different types of furnaces.

Books Recommended

1.     Brame J S and King J C, “Fuels- Solid, Liquid and Gaseous” , St. Martin Press
2.     Sarkar S, “Fuels and combustion”, Longman publishers India Ltd.., IInd Edition
3.     Haslam R T and Russel R P, “Fuels and their combustion” , McGraw Hill
4.     Gupta O P, “Elements of Fuels, Furnaces and Refractories”, Khanna Publishers
5.     Griswold J, “Fuels combustion and furnaces”, McGraw Hill

CB-221        Microbiology Laboratory                                            [0 0 2 1]

1.     To study the microscope.
2.     Calibration of pH meter.
3.     Preparation and sterilization of the medium for bacteria yeast and mold.
4.     Preparation of slants /plates /deeps for culture of bacteria yeast and mold.
5.     Asceptic transfer of microbial cultures.
6.     To study the morphology of bacteria, yeast and mold.
7.     .Staining of bacteria (Gram’s stain).
8.     The quantitative bacteriological examination of water/milk.
9.     Determination of phenol coefficient.
10.    a) Determination of cell mass in a fermentation broth.
       b) Calibration of cell mass vs cell number and cell mass vs optical density

CB-222        Biochemistry Laboratory                                           [0 0 3 2]

1.     Determination of reducing sugar by dinitro-salicylic (DNS) method.
2.     Protein estimation by Lowry’s method.
3.     Estimation of DNA by diphenylamine reagent method.
4.     Estimation of RNA by orcinol reagent method.
5.     Determination of Michaelis constant of enzymes.
6.     Agarse gel electrophoresis of DNA.
7.     Determination of isoelectric point of casein.
8.     Sephadex gel filtration chromatography.
9.     Extraction of lipids from egg yolk.
10.    Separation by amino acids by paper electrophoresis.
CB-223        Mechanical Operations Laboratory                                    [0 0 2 1]

1.     Determination of power consumption and study of agitation and mixing characteristic
       of a fluid.
2.     Determination of drag coefficient from the plot of drag coefficient Vs modified
       Reynolds No.
3.     Pressure drop through a packed bed: To plot the graph between modified Reynolds
       no. Vs modified friction factor and verify Ergun Equation in packed column.
4.     To find out the collection efficiency of a cyclone separator.
5.     Determination of screening efficiency in a vibrating screen.
6.     Plate and frame filter press: determination of cake resistance and filter medium
7.     Determination of specific cake resistance in constant pressure vacuum filtrations
8.     To study filtration characteristics of a leaf filter.
9.     To study the flow through a helical coil.
10.    To study the crushing efficiency of a roll crusher.
11.    To study flow through an orifice meter.

CB-224        Energy Engineering Laboratory                                       [0 0 3 2]

1.     To determine the flash point of a given sample.
2.     To determine the Smoke Point of a given sample
3.     To study the Distillation of Petroleum Products
4.     To determine the calorific value of a fuel using Peroxide Bomb Calorimeter
5.     To determine the sediment in Crude Petroleum and Fuel oils by Extraction
6.     To determine the Vapour Pressure of a given sample by Reid method
7.     To determine the Cloud Point and Pour Point of a given sample
8.     To study the burning properties of a given sample.
9.     To determine the Melting Point of Petroleum wax

CB-227        Chemical Technology Laboratory                                       [0 0 2 1]

1.     To determine the acid value of a vegetable oil.
2.     To determine the saponification value of vegetable Oil
3.     To determine the acid value of Lubricating Oil
4.     To estimate the given reducing sugar
5.     To estimate the given non reducing sugar
6.     To study loss on Heating of Tar and Bitumen
7.     To determine the sediment in Crude Petroleum and Fuel oils
8.     To determine the viscosity of a given sample by Redwood Apparatus
9      To standardize the given Fehling’s solution.
10.    To Study the given polymerization reaction
11.    To determine the viscosity of a given sample by U-tube viscometer .

CB-300        Practical Training                                                  [0 0 0 8]

Each student is required to undergo compulsory three months practical training in reputed
industry/ CSIR Laboratory or any institute of National Importance including National Institute
of Technology, Jalandhar etc as approved by the Department.

CB-301        Mass Transfer – I                                                   [3 1 0 4]

Mass Transfer Operations: Classification of mass transfer operation, choice of separation
Diffusion in Mass Transfer: Steady state molecular diffusion in fluids at rest and in
laminar flow, molecular diffusion in gases, molecular diffusion in liquids, diffusivity in liquids
and gases, momentum and heat transfer in laminar flow.
Mass Transfer Coefficient: Local and overall mass transfer coefficient, heat and mass
transfer analogy, eddy diffusivities, film theory, penetration theory, surface renewal theories,
combination film theory and surface stretch theory.
Interphase Mass Transfer: Equilibrium, local two phase mass transfer coefficients, Local
overall Mass Transfer coefficients, material balance for co current & counter current
processes, cascades and concept of Ideal stage and stage efficiencies, continuous contact
Gas Absorption: Choice of solvent, Estimation of number of ideal stages – Graphical and
Analytical methods, Minimum solvent flow rate, Significance of absorption factor, number of
transfer units and height of a transfer unit (NTU & HTU) concepts, packed column for
absorption, rate of absorption, height of column based on condition in gas film and liquid film,
height based on overall coefficients, equipment for gas absorption
Drying: Equilibrium in drying, batch drying and rate of batch drying, time of drying, Through
circulations drying & continuous drying, batch & continuous drying equipments.

Books Recommended

1.      Geankopolis C J, “Transport Processes and Separation Process Principles”, Prentice
        Hall of India, 4th Edition, Eastern Economy Edition (2004)
2.      Treybal R E , “Mass Transfer Operations” 3rd ed. , McGraw Hill (1980)
3.      McCabe W L and Smith J C “Unit Operations of Chemical Engineering”, McGraw
        Hill (2001).
4.      Coulson J M and Richardson J F “Chemical Engineering , Vol. 2, 5”, McGraw Hill
        (1999 )
5.      Walter L, Badger & Julius T.Banchero “Introduction to Chemical Engineering”,
        McGraw Hill (1997).

CB-302          Mass Transfer –II                                                          [3 1 0 4]

Mass Transfer equilibria for vapour - liquid, liquid – liquid , solid - liquid and solid- gas
Distillation : Raoult’s Law and Dalton’s law, partial vaporisation and partial condensation,
relative volatility, differential distillation & flash distillation, steam distillation, Lewis Sorel and
MaCabe –Thiele methods & numerical, Ponchon Savarit method, Underwood and Fenske
equations, total reflux , minimum and optimum reflux ratios, multiple feeds and side streams
Liquid – Liquid Extraction: Ternary phase diagrams & choice of solvent, single stage and
multistage cross current, co-current and counter current extraction operation for immiscible
and miscible solvents, related numerical problems, continuos contact extractors.
Leaching: Mass transfer in leaching, equipment for leaching, single stage and multistage
cross current, co-current and counter current leaching operations, related numerical
Adsorption: Introduction and the nature of adsorbent, adsorption equilibria, the Langmuir
isotherm , BET isotherm and Gibbs isotherm, potential theory and adsorption equipments.
Crystallization: Formation of nuclei, nuclei growth and properties of crystals, effect of
impurities on crystals formation, effect of temperature on solubility, caking of crystals, yield
of crystals, crystallisers, related numerical problems

Books Recommended

1.      Geankopolis C J, “Transport Processes and Separation Process Principles”, Prentice
        Hall of India, 4th Edition, Eastern Economy Edition (2004)
2.      Treybal R E , “Mass Transfer Operations” 3rd ed. , McGraw Hill (1980)
3.     McCabe W L and Smith J C “Unit Operations of Chemical Engineering”, McGraw
       Hill (2001).
4.     Coulson J M and Richardson J F “Chemical Engineering , Vol. 2, 5”, McGraw Hill
       (1999 )
5.     Walter L, Badger & Julius T.Banchero “Introduction to Chemical Engineering”,
       McGraw Hill (1997).

CB-303         Chemical Reaction Engineering – II                                   [3 1 0 4]

Non Ideal Flow: Non ideal flow patterns, E,F &C Curve, Mean residence time, Models for
non ideal flow, N Tanks in series model, conversion in a reactor using RTD data .
Heterogeneous Process: Global rates of reaction, Types of Heterogeneous reactions
Catalysis, The nature of catalytic reactions, Mechanism of catalytic reactions.
Physical Adsorption and Chemisorption: Physical             adsorption and Chemisorption,
Adsorption isotherms, Assumptions,Rates of adsorption isotherm, problems.
Solid Catalysts : Determination of surface area, Void volume and solid density, Pore
volume distribution , Theories of heterogeneous catalysis, Classification of catalysts, catalyst
preparation, Promoter and inhibitors, Catalysts Deactivation
Rate Equations for Fluid solid catalytic reactions: Rates of Adsorption, Surface reaction,
Desorption , Rate limiting step, Power Law, Langmuir Hishelwood rate, Eley Rideal
mechanism , Packed bed reactor and fluidized bed reactor, Numerical Problems
Intra Pellet Mass Transfer : Gaseous diffusion in single cylindrical pore, Different modes
of diffusion: Bulk diffusion, Knudsen diffusion and surface diffusion, Diffusion in Liquids,
Diffusion in Porous Catalyst, Concepts of effective thermal conductivity and effective
diffusivity, Effectiveness factors
Reactors : Fixed Bed Catalytic Reactor, Single and multibed adiabatic reactors, Multitubular
fixed bed reactor
Introduction to Fluid Reactions: Kinetic Regimes for Mass Transfer and Reaction, Film
Conversion parameter, Clues to the kinetic Regime from solubility data, Clues to the
Kinetic Regime from equipment, Applications to design

Books Recommended

1.     Levenspiel O, “Chemical Reaction Engineering”, 3rd Ed , John Wiley & Sons,
       Singapore (1999).
2.     Fogler H Scott, “Elements of Chemical Reaction Engineering”, 3rd ed, Prentice Hall
       Inc. (1999).
3.     Smith J M , “Chemical Engineering Kinetics” , McGraw Hill , 3rd ed. (1981).
4.     Hill, C G, “ Chemical Engineering Kinetics and Reactor Design”, John Wiley (1977).
5.     Coulson J M and Richardson J F, “Chemical Engineering Volume 3”, Pergamon
       Press (1999).

CB-304         Process Economics and Management                                     [3 0 0 3]

Cost Estimation: Factors affecting investment & production costs, Capital investments
(Fixed and working capital), Types of capital cost estimates, Cost Indexes, Estimating
equipment costs by scaling 6/10 Factor Rule, Purchase Equipment Installation , Insulation
costs, Instrumentation & Control, Piping , Electrical Installation , Service facilities, Land,
Engineering . & Supervision , Start –up expenses. Methods of Estimating Capital
Investment, Estimation of total product cost, Different costs involved in the total product
for a typical Chemical Process plant.
Interest & Investment Costs : Types of interest ( simple & compound interest ), Nominal
& Effective Rates of interest, Continuous interest, Present worth & discounts, perpetuities,
capitalized costs, Interest & Investment costs.
Taxes & Insurance:         Types of taxes, Property taxes, excise taxes, income taxes,
Types of Insurance & Legal Responsibility.
Depreciation: Purpose of Depreciation as cost, Types of Depreciation, Depletion, Service
life., Salvage value, Present value, Methods of Determining Depreciation , Straight- line
method, Declining Balance Method, Sum of the years Digits method, Sinking Fund Method,
Single Unit & Group Depreciation.
Profitability, Alternative Investments & Replacement: Profitability standards,
Mathematical methods of profitability evaluation: Rate of return on investment, Discounted
cash flow method, Net Present worth, Capitalised costs, pay out period. Determination of
Acceptable investment, Alternatives when an investment must be made, Alternative analysis
by method of return on incremental investment, Alternative analysis incorporating minimum
return as a cost, Replacements, Balance sheets & Income statement.
Optimum Design: General procedure for Determining optimum conditions, Procedure with
one variable, Procedure with Two or More variables, Break even chart for production
schedule and its significance for optimum analysis. Examples of optimum design in a
Chemical Process Plant.

Books Recommended

1.      Peters, M S & Timmerhaus K D,“Plant Design and Economics for Chemical
        Engineers”, McGraw Hill , New York , 4th Edition (2003)
2.      Ulrich , G D,“A Guide to Chemical Engineering Process Design and Economics”,
        John Wiley (1984)
3.      Guthrie K M, “ Process Plant Estimation, Evaluation and Control”, Craftsman Solano
        Beach, California (1974)
4.      Douglas, “ Conceptual Design of Chemical Processes”, McGraw Hill (1998)
5.      Valle Riestra , “Project Evaluation in Chemical Process Industries”, McGraw Hill

CB-305          Petroleum Refining Engineering                                              [3 1 0 4]

Scope and Purpose of Refining: Global and Indian refining scenario, Petroleum refining
industry in India practice and prospects, An overview of the entire spectrum of the refinery
products, refinery configuration development, Physio chemical characteristics of Petroleum
and Petroleum products
Refinery Distillation Processes: Desalting and Stabilization of crude, Process description
of typical simple distillation, Fractional distillation, crude oil distillation, vacuum distillation etc,
Degree of separation (5-95 gap) and degree of difficulty of separation ( t 50), Packie charts,
ASTM, TBP and EFV Distillation.
Fuel Refining: Cracking, coking, reforming, alkylation, isomerisation, polymerization,
sweetening, visbreaking.
Lube Refining: Solvent extraction, dewaxing, propane deasphalting.
Wax Refining: Deoiling of crude wax, crystallization, catalytic, sweating microcrystalline and
petroleum wax applications.
Hydro processing: Hydro cracking, hydro treating, hydro finishing.
Refinery Feedstock: Nature and effect of different types of refinery feedstock and their
impurities on refinery configuration and operation.
Refinery Gas Processing: Process description of typical light ends unit, acid gas removal
using gas treating processes.
Two Phase oil and gas separation equipment : Types, their description , vessel sizing .
Theory of separation and separator design.
Three phase Oil gas and water separators : Types of separators, their description.
Various control and vessel internals, theory and sizing of three phase separator . LACT
Books Recommended

1.     Nelson W L, “Petroleum Refinery Engineering”, Mc Graw Hill Book Co. 1985)
2.     Watkins R N, “Petroleum Refinery Distillation”, Gulf Publishing Co.
3.     Gary J H and Handework G E, “Petroleum Refining Technology and Economics”,
       Marcel Dekker, Inc. (2001).
4.     Jones D S J, “Elements of Petroleum processing”, John Wiley & Sons (1995)
5.     Waquier J P, “Petroleum Refining” Vol. I & II Editions, Technip (1995)

CB-306         Process Plant Design –II                                             [1 0 2 2]

Heat exchangers: Classification of shell and tube heat exchanger, material of construction,
cleaning of heat exchangers, heat transfer fluid, agitated vessels, description of shell, tubes,
bonnet and channel, pass partition plate, nozzle, baffles, tie rods, baffle spacers, flanges,
gaskets and expansion joints.
Design of heat exchangers: Energy balance, heat duty consideration and process design
of double pipe and shell and tube heat exchangers.
Mass Transfer Equipments: Types of mass transfer equipments, packed and tray type
Tray Hydraulics: Bubble cap columns, perforated plate columns and packed towers
Process Design: Process design of tray and packed towers.

Books Recommended

1.     Kern D Q, “Process Heat Transfer”, McGraw Hill (2001)
2.     Perry’s, “Handbook of Chemical Engineering” McGraw Hill, 7th Ed (1997).
3.     Coulson J M and Richardson R E, “Chemical Engineering” Vol 2 and 6, Pergamon
       Press (1998).
4.     Van Winkle M, “ Distillation”, Ist Ed. , McGraw Hill Company, New York (1967).
5.     Ludwig E E, “Applied Process Design for Chemical and Petrochemical Plants (Vol.
       1,2 and 3)”, 3rd Ed., Gulf Publishing Company, Houston (1995)

CB-307         Bioprocess Engineering                                               [3 1 0 4]

Introduction to Bioprocess Engineering: Mass and energy balances in bioprocesses,
flow sheet and process calculations, metabolic stoichiometry of growth and product
formation, material balance and energy balance with recycle, by pass and purge streams.
Microbial Growth Kinetics: Batch, continuous and fed batch, mass balance in series of
vessels, recycle system
Media Sterilization : Methods of media sterilization, batch and continuous sterilization,
kinetics of sterilization
Air Sterilization: Methods of air sterilization, mechanism of air sterilization, filter design.
Aeration and Agitation: Mass transfer and microbial respiration , bubble aeration and
mechanical agitation, correlation between oxygen transfer coefficient and operating
variables, factors affecting volumetric oxygen transfer, rheology of fermentation fluids
Scale Up: Scale up concepts, criteria for bioreactors scale up.
Design and Analysis of Bioreactors: Component of fermentors and their design, asceptic
operations, RTD studies in bioreactors
Monitoring of Bioprocesses: On line data analysis for measurement and control of
important physicochemical and biochemical parameters, parameter estimation techniques
for biochemical processes, parameter estimation techniques for biochemical processes,
Computer based data acquisition,
Modelling and Simulation of Bioprocess: Study of structured models for analysis of
various bioprocess, model simulation using software packages
Books Recommended

1.     Lee J M, “Biochemical Engineering” , Prentice Hall (1992)
2.     Shuler M L, Kargi F, “ Bioprocess Engineering- Basic Concepts” , 2nd ed, Prentice
       Hall of India Ltd. ( 2002)
3.     Aiba S, Humphrey A E and Millis N F ,“Biochemical Engineering” , Academic Press
4.     Stanbury P F and Whitaker A, “Principles of Fermentation Technolgy,” Pergamon
       Press (1995)
5.     Bailey J E and Ollis D F, “Biochemical Engineering Fundamentals” , McGraw     Hill

CB-309         Process Plant Design –I                                             [1 0 3 3]

Introduction: Introduction to principles involved in the design and construction of plant.
Design preliminaries: Design codes, pressure, temperature, factor of safety, corrosion
allowance, weld joint efficiency factor, design loadings, Poisson’s ratio, dilation of pressure
vessels, criteria of failure, material of construction.
Storage tanks: Introduction to Indian standards for storage tanks and their use to design
cylindrical and spherical vessels under internal pressure, fixed roof and open roof tanks.
Mechanical design: Mechanical design of tall vessels for distillation and absorption
Design of supports: Design of supports for vertical and horizontal vessels.

Books Recommended

1.     Bhattacharya B C, “Chemical Equipment Design”, CBS Publisher (1985).
2.     Sinnott R K , Coulson & Richardson, “Chemical Engineering (Vol.6)”, 2nd ed,
       Butterworth Heinemann, Oxford (1998).
3.     Ludwig E E, “Applied Process Design for Chemical and Petrochemical Plants(Vol.
       1,2 and 3)” , 3rd Ed., Gulf Publishing Company, Houston (1995).
4.     Perry’s, “Handbook of Chemical Engineering”, 7th Ed, McGraw Hill (1997).
5.     Ulrich, G D, “A Guide to Chemical Engineering Process Design and Economics”,
       John Wiley (1984).

CB-310         Bioinfomatics                                               [3 0 0 3]

Introduction and Definition: Definition of Bioinformatics, Applications, Information
Biological Databases: Concepts, Introduction to SQL, Various Biological Databases.
Computational Biology: Sequence analysis, Pair wise and multiple sequence alignment,
Similarity searches, Phylogenetic analysis.
Bioinformatics Software: Clustal W, oligoprimer. ALSCRIPT, MOLSCRIPT, Rasmol,
Phylip, Submitting sequence to databases.
Biocomputing Languages: HTML, XML, CML, PERL, UNIX

Books Recommended

1.     Westhed D R , Parish J H and Twyman R M, “Bioinformatics” ,Viva Books Pvt. Ltd. ,
       New Delhi (2003).
2.     Gibas C , Gambeck P “Bioinformatics Computer Skills”, O’Reilly, Tokyo
3.     Attwood T K, and Parry- Smith “ Introduction to Bioinformatics”, Pearson Education ,
       Singapore (2000).
4.     Mount D W “Bioinformatics” CBS Publsiher New Delhi (2003).
5.     Brgeron Bryan, “ Bioinformatics Computing”, Prentice Hall of India (2003).

CB-311        Enzyme Technology                                                     [3 0 0 3]

Basic concepts of enzyme: Mechanism of Enzyme Action and kinetic of reaction: Concept
of active sites, and energetics of enzyme substrate complex formation, Specificity of enzyme
action, Estimation of Michaelis-Menten Parameter
Stability of enzymes: PH, Temperature, Mechanical forces, Heterogeneous system.
Production and purification of enzymes: Extract from plant, animal and microbial sources,
Methods of characterization of enzymes, Development of enzymatic assays.
Enzyme immobilization: Physical and chemical techniques for enzyme immobilization
adsorption, Matrix entrapment, Encapsulation, cross linking, covalent binding, Advantages
and disadvantages of different immobilization techniques.
Applications of enzymes: Classification of enzymes, Commercial application of enzymes in
food, Pharmaceutical and other industries, Enzymes for analytical and diagnostic
Mass transfer effects in immobilized enzymes: Analysis of film and pore diffusion effects
on kinetics of immobilized enzyme reaction, Formulation of dimensionless groups,
Calculation of effectiveness factors

Books Recommended
1.    Lee J M, “Biochemical Engineering” , Prentice Hall (1992)
2.    Bailey and Ollis, “Biochemical Engineering Fundamentals” , McGraw Hill (1996)
3.    Lehninger, A L “Principles of Biochemistry”, Butterworth Publishers,New York(1993)
4.    Conn E E and .Stumpf P K “Outlines of Biochemistry” John Wiley and Sons, New
      York (1987)
5.    Stanbury P F and Whitaker A, “Principles of Fermentation Technolgy,” Pergamon
      Press (1995)

CB-312        Protein Engineering                                                   [3 0 0 3]

Structure of protein: Primary, secondary, tertiary, quaternery structure, Protein folding Post
translation modification.
Methods to determine structure of proteins: Protein structure determination, X-Ray
analysis of protein, NMR and mass Spectroscopy, Protein characterization, 2 D Gel
Methods to alter primary structure of protein: Random mutation Site directed mutation,
Catalytic activity.
Protein engineering benefit: Industry, Medicine
Structure and function prediction: Protein Bimolecular interaction, Drug protein interaction

Books Recommended

1.     Lehninger, A L “Principles of Biochemistry”, Butterworth Publishers, New York
2.     Conn E E and .Stumpf P K “Outlines of Biochemistry” John Wiley and Sons,New
       York (1987)
3.     Walsh G , “ Proteins Biochemistry and Biotechnology” John Wiley and sons (2003).
4.     Permington S R , Dunn M J, “Proteomics from Protein sequence to function” , Viva
       Books Pvt. Ltd., New Delhi
5.     Holtje H D, Sippl W and Rognan D , Folkers G , “ Molecular Modeling, Basic
       Principles and Applications”, Wiley VCH Germany (2002).

CB-313        Biopharmaceutical Technology                                          [3 0 0 3]
Introduction to Biopharmaceutical: Biopharmaceutica, Current status and future
Drug development process: Drug discovery, Patenting, Delivery of pharmaceutical,
Preclinical trials, Drug regulatory authorities.
Drug manufacturing process: Manufacturing practice, Facilities, Analysis of products.
Pharmaceutical products: Interleukins, interferon, Growth factor, Hormones, Therapeutic
enzymes, Antibodies, Vaccines, Nucleic acid therapeutics , Antibiotics.

Books Recommended

1.     Leon Lachman tet al “Theory and Practice of Industrial Pharmac”,, 3 Edition , Lean
       and Febiger (1986).
2.     Remington’s Pharmaceutical Sciences, Mark Publishing and Co. (2000)
3.     Klefenz H “Industrial Pharmaceutical Biotechnology” Wiley – VCH Verlag GmbH
       Germany (1999).
4.     Vyas S P and Dixit U K “Pharmaceutical Biotechnology” CBS Publisher New Delhi
5.     Moo- Young Murray , “Comprehensive Biotechnology Vol. IV”, Pergamon Press New
       York (1985).

CB-314        Petrochemical Technology                                             [3 0 0 3]

Petrochemicals – an overview. Growth of Global and Indian petrochemical industry.
Petrochemical feed stock.
Technologies for the manufacture of Bulk organic Chemicals: Steam Reforming, Syn
gas manufacture, Steam Cracking, Olefin Separation, Up gradation of C2,C3,C4,C5 cuts,
Separation of ethyl benzene, hydrogen, benzene, toluene, xylene isomers
Aromatic conversion process: Xylene isomerisation.
Manufacture of the major downstream products and their uses, properties: Methanol,
Formaldehyde, Ethylene oxide, Ethylene glycol, Poly-vinyl chloride, LDPE and HDPE,
Propylene oxide, Iso-Propyl Alcohol, Butadiene, isobutylene, Acetic acid, Maleic anhydride,
Nylon 6, Nylon 66, Polyethylene terepthalate, Formaldehyde resins, Styrene Butadiene
Rubber, Alkyl Benzene Sulfonate, Butanediol, 1,4-butene

Books Recommended

1.     Chauvel A Lefebvre G, “Petrochemical Process Vol. I & II”, Gulf Publishing Company
2.     Rao G, Sitting “Dryden’s Outline of Chemical Technology”.
3.     .Maiti Sukumar, “Introduction to Petrochemicals”,Oxford & IBH Publishing Co. (1992).
4.     Hatch L F, Matar S, “From Hydrocarbons to Petrochemicals,” Gulf Publishing
       Company (1981)
5.     Lee S, “Methane and its Derivaties”, Marcel Dekker (1997).

CB-315         Transport Phenomena                                                 [3 0 0 3]

Momentum Transport: Viscosity and the mechanism of momentum transport, newton’s law
of viscosity, non- newton fluids, pressure and temperature dependence of viscosity, theory of
viscosity of gases at low density, theory of viscosity of liquids.
Velocity Distributions in Laminar Flow: Shell momentum balances: boundary conditions,
flow of a falling film, flow through a circular tube, flow through an annulus, adjacent flow of
two immiscible fluids.
The Equations of Change for Isothermal System : To equation of continuity, the equation
of motion, the equation of mechanical energy.
Interphase Transport in Isothermal System: Definition of friction factors, friction factors for
flow in tubes, friction factors for flow around spheres, friction factors for packed columns.
Thermal Conductivity and the Mechanism of Energy Transport: Fourier’s Law of heat
conduction, temperature and pressure dependence of thermal conductivity in gases and
liquids, theory of thermal conductivity of gases at low density, theory of thermal conductivity
of liquids, thermal conductivity of solids.
Temperature Distributions in solids and in Laminar Flow: Shell energy balances;
boundary conditions, heat conduction with an electrical heat source, heat conduction with a
chemical heat source, heat conduction through composite walls: Addition of Resistance,
Forced Convection, Free Convection.
The Equations of change for Nonisothermal systems: The equations of energy, the
energy equation in curvilinear coordinates, the equations of motion for forced and free
convection in nonisothermal flow, summary of the equations of change, use of equation of
change to set up steady – state heat transfer problems.
Diffusivity and the Mechanism of Mass Transport: Definition of concentrations, velocities
and mass fluxes, fick’s law of diffusion, theory of ordinary diffusion in gases at low density,
theory of ordinary diffusion in liquids.
Concentration Distributions in Solid and in Laminar Flow: Shell mass balances:
boundary conditions, diffusion through a stagnant gas film, diffusion with heterogeneous
chemical reaction, diffusion with homogeneous chemical reaction, diffusion into a falling
liquid film l forced – convection mass transfer, diffusion and chemical reaction inside a
porous catalyst: the “effectiveness factor”.
Analogies between Heat, mass and momentum and transfers.

Books Recommended

1.     Bird R B, Stewart W E and Light fort R N, “Transport Phenomena”, John Wiley and
       Sons (2002).
2.     Welty J R , Wilson R E and Wicks C E , “Fundamentals of Momentum , Heat and
       Mass Transfer”, 4th ed,John Wiley and Sons (2001 ).
3.     John C Slattery, “Momentum, Energy and Mass transfer in continua”, McGraw Hill,
       Co. (1972).
4.     Bennet C U and Myers J E, “ Momentum, Heat and Mass Transfer” Tata McGraw Hill
       Publishing Co. (1975)
5.     Robert S Brodkey and Harry C Hersing, “ Transport Phenomena a Unified approach”
       McGraw Hill Book Co. (1988).

CB-321         Heat Transfer Laboratory                                            [0 0 2 1]

1.     Determination of emmissivity for surface heat transfer
2.     Determination of thermal conductivity of liquid
3.     Determination of thermal conductivity of insulating powder
4.     Determination of heat transfer coefficient by natural convection
5.     Determination of heat transfer coefficient by forced convection
6.     Determination of heat transfer coefficient for pin fin by natural convection
7.     Determination of heat transfer coefficient for pin fin by forced convection
8.     Determination of heat transfer coefficient by dropwise and filmwise condensation
9.     Determination of overall heat transfer for parallel flow in double pipe heat exchange
10.    Determination of overall heat transfer coefficient for counter flow in double pipe
       heat exchanger
11.    To conduct test on heat pipe and compare the temperature distribution
12.    Determination of heat transfer coefficient in shell & tube heat exchanger
13.    Determination of overall heat transfer coefficient in an open pan evaporator

Note : At least 8 experiments to be performed .
CB-322        Mass Transfer Laboratory                                             [0 0 2 1]

1.     To plot the ternary phase diagram for acetic-acid – water Toluene
2.     To draw the tie line and to determine plait point for ternary system
3.     To determine the diffusivity of acetone in air
4.     To study the drying characteristics of the given wet material (Natural Convection)
5.     To determine the Mass Transfer Coefficient for vaporization of naphthalene in air
6.     To verify Rayleigh’s Equation for Batch distillation
7.     To find HETP and HTU for packed distillation column
8.     To purify turpentine oil having high boiling point using steam distillation
9.     To determine VLE data for methanol –water and to compare it with literature data
10.    To determine the mass transfer coefficient by carrying out liquid-liquid extraction in a
       packed column using acetic acid- toluene-water system
11.    To study the drying characteristics of the given wet material (forced convection)
12.    To study the process of crystallization in an agitated batch crystallizer and to plot a
       graph between weight of crystals Vs temp.
13.    To find out mass transfer coefficient in a drop wise liquid –liquid extraction.

Note : At least 8 experiments to be performed

CB-327        Bioprocess Engineering Laboratory                                    [ 0 0 2 1]

1.     Sterilization of bio reactor.
2.     To estimate growth kinetic parameters of Escherichia coli .
3.     To determine Volumetric Oxygen Transfer Coefficient (kla) in fermentation system by
       dynamic method.
4.     To determine Volumetric Oxygen Transfer Coefficient (kla) in fermentation system by
       sulphite oxidation method.
5.     To determine mixing time in a stirred tank reactor (STR).
6.     Estimation of cell maintenance coefficient and true growth yield by studying the mass
       and energy balance during cell growth.
7.     Comparison between aerobic and anaerobic fermentation.
8.     Heat balance across a batch sterilization process.
9.     To determine the control characteristics of a pH controller.
10.    To determine Residence Time Distribution (RTD) for a continuous stirred tank reactor

CB-400        Project Phase –I                                                     [0 0 4 2]

Every student will be required to submit a project report in a typed form, on a topic
selected by the student, but specifically approved by the faculty member, who will guide
the student or on a topic to be assigned by one or more faculty members.

The project work on the topic will consist of either some investigational work, computer
simulation or design problem or experimental set up of some development work of or
prototype equipment. Every student will be orally examined in the topic incorporated in
the project and in the project and in the related area of specialization.

The student will be required to submit three copies of his/her project report to the
department office for record. One copy each for the department library, participating
faculty and students own copy.
CB-400        Project (Phase –II)                                               [0 0 16 8]

Every student will be required to submit a project report in a typed form, on a topic
selected by the student, but specifically approved by the faculty member, who will guide
the student or on a topic to be assigned by one or more faculty members.
The project work on the topic will consist of either some investigational work, computer
simulation or design problem or experimental set up of some development work of or
prototype equipment. Every student will be orally examined in the topic incorporated in
the project and in the project and in the related area of specialization.
The student will be required to submit three copies of his/her project report to the
department office for recor. One copy each for the department library, participating faculty
and students own copy.

CB-401        Chemical Process Control                                          [3 1 0 4]

Laplace Transform : Transforms of simple function, Transforms of Derivative, Initial value
theorem and Final value theorem, Transform of Integral
Response of First order system: Mercury thermometer & its transfer function,       Forcing
functions, Liquid Level System , Liquid Level Process with constant flow out let,
Linearization , Mixing tank & R.C. Circuit
Response of First order system in series: Non interacting System, Interacting System
Higher order System :Transfer function of second order system, Underdamped System,
Impulse function , Sinusoidal function,Transportation lag,
Control System : Components of control system, block diagram, Negative and Positive
feed back, Servo problem and Regulation Problem, Development of Block diagram
Controllers and final control element: Control Valve , Proportional controller, Integral &
Derivative controller, Comparison.
Closed Loop Transfer functions: Determination of transfer function
Transient response of control system: Proportional control for set point change,
Proportional control for load change, Proportional Integral control for load
change,Proportional Integral Control for set point change
Stability: Concept of stability, Stability Criteria, Routh test for stability
Introduction to frequency response: Bode diagram for first order, Bode diagram for
proportional, Integral and derivative control, Second order system
Control System Design by frequency response : Bode stability criteria, Gain and phase
Margin, Ziegler Nichols Controller settings,
Advanced Control Strategies: Cascade Control, Feed forward control, Ratio control, Dead
time compensation.

Books Recommended

1.     Coughanower D R, “Process System Analysis and Control”, McGraw Hill, 2nd ed.
2.     Seborg, Edgar, and Mellichamp, “Process Dynamics & Control”, John Wiley 2nd. Ed.
3.     Harriot, “ Process Control”, Tata Mcgraw Hill (2000)
4.     Stephanopoulos,” Chemical Process Control - An Introduction To Theory &
       Practice”, Ist Ed., Prentice Hall of India Private Limited (2003 ).
5.     Luyben W L, “ Essentials Of Process Control” McGraw Hill (1997).

CB-402        Industrial Biotechnology      [30 03]

Introduction to Industrial Biotechnology: Definition and scope of Industrial
Biotechnology, historical overview of industrial fermentation processes and products.
Role of Bioprocess Engineer         in bioprocess development on an industrial scale,
Microorganisms and various unit operations involved, process parameter optimization,
products and market economics relating to modern industrial biotechnology.
Raw materials and microorganism for fermentation process: Isolation, preservation and
maintenance and improvement of industrial microorganisms for overproduction of primary
and secondary metabolites, media requirements for fermentation processes, carbon,
nitrogen, minerals, vitamins and other nutrients, simple and complex media, media
 Production of Primary Metabolites: Organic acids, alcohols, acetone and butanol etc.,
Production of Secondary Metabolites: Antibiotics – Beta lactam antibiotics, amino
glycosides, tetracyclines, erythromycin, vitamins and steroids.
Commercially Important Products: Enzymes and                 recombinant proteins having
therapeutic and diagnostic applications, specialty by products for agricultural, food and
pharmaceutical industries, biopesticides, biofertilizer and plant growth stimulants,
biopolymers, single cell proteins,
baker’s yeast, high fructose corn syrup.
Biological Waste Treatment : Objective and overview of various aerobic and anaerobic

Books Recommended

1.     Crueger W and Crueger A, “Biotechnology : A Text book of Industrial Microbiology”
       Sinouer Associate, Inc. Sunderland MA, USA(1990)
2.     Casida L E, “Industrial Microbiology” , New Age International Publishers Ltd.(2003)
3.     Reed G, “Prescott and Dunn’s Industrial Microbiology” CBS publishers and
       distributors, New Delhi (1987). ,
4.     Mansi E M T EL, Bryce C F A ,“Fermentation Microbiology and Biotechnology”. Ane
       Books Publishers and Distributors (2003)
5.     Kumar H D, “ A Text book of Biotechnology”, EWP (1994).

CB-403      Molecular Biology and Genetic Engineering                         [3 0 0 3]

Introduction to Molecular Biology and Genetic Engineering: Gene its concepts and
inheritence, development of Molecular Biology and Genetic Engineering, DNA–structure,
forms and replication, RNA–types and functions, ribosome and translation, regulation of
transcription and translation
Genome Organisation: Genome size and complexity, the super coiling of DNA the
structure of prokaryotic and eukaryotic chromosome, satellite DNA, centromere and
telomere structure.
Mutation: Spontaneous versus induced mutations, types of mutations, mechanism of DNA
repair, mutations frequency gene transfer and expression in bacteria, eukaryotes and
Bacteria: Transformation, transduction and conjugation.
Eukaryotes: Transcription, RNA splicing, Retroviruses.
Virus: Bacteriophages, genome its organization and its expression, virus of eukaryotes .
Basics of Recombinant DNA: Role of genes within cells, elucidation of genetic code,
genetic elements that control gene expression, method of creating recombinant DNA
research, restriction –modification    enzymes and mapping in eukaryotes, plasmids,
bacteriophage lambda and M-13 molecular biology, RNA tumour viruses- replication and
Construction of c DNA libraries: Construction of genomic and c DNA libraries, methods
of nucleic acid sequencing, expression of cloned genes
Tools and Techniques: labeling of nucleic acids, hybridization and blotting, PCR
Application of Recombinant DNA Technology: In agriculture, transgenic plants and
animals, gene therapy, synthesis of important molecules like insulin, growth hormone
interferon etc

Books Recommended

1.     De- Robertis, F D P and De Robertis E M F, “Cell and Molecular Biology”,Saunders,
       Philadelphia (1991)
2.     Lewin B “Gene VII”, Oxford University Press, Oxford (1990)
3.     Sambrook J, Fritsch E F and Maniatis T, “MolecularCloning” ., Cold            Spring
       Harbor Laboratory Press (1989 )
4.     Pelczar M J, Chan E C S and Krieg N R, “Microbiology,”Mc Graw Hill, New York
5.     Lehninger A L, “Principles of Biochemistry”, Butterworth Publishers, New York (1993)

CB-404         Environmental Engineering and Safety                                    [3 1 0 4]

Air Pollution: Primary pollutants-particulate matter , dust ,smoke fumes, mist, fog & aerosol,
oxides of sulphur , nitrogen oxides. secondary pollutants -sulphur trioxide , Peroxyacetyl
nitrate, ozone, aldehydes etc. control equipments- collection efficiency, settling chamber,
multi tray gravity settling chamber, cyclone separator, electrostatic precipitator, fabric filter
system, scrubber or wet collectors , spray towers , centrifugal scrubbers, packed bed
scrubber, venturi scrubber.
Lapse rate : Temperature lapse rate , adiabatic lapse rate. atmospheric stability-
inversion, radiation inversion, subsidence inversion, double inversion .plume behaviour .
Water Pollution : Physical characteristics- total solids, odors, temperature , color. chemical
characteristics- organic matter , protein , carbohydrates , fats & Oils,
BOD, COD , TOC, TOD , ThoD, inorganic matters, pH , chlorides , Alkalinity , nitrogen
phosphorus,heavy         metals,gases. biological characteristics-      microorganism, protista,
viruses. primary treatments- pretreatment , sedimentation, floatation. secondary treatments-
activated sludge process, trickling filters. tertiary treatments-coagulation and filtrtion , reverse
osmosis , ion exchange biological ponds etc.
Solid Waste: Solid waste treatment- sanitary landfill, incineration , composting.
Safety: Introduction, toxicity, flammability, explosions, pressure& temperature, safety
training, emergency planning.

Books Recommended

1.     Metcalf and Eddy , “Waste Water Treatment Disposal and Reuse” ,Tata McGraw
       Hill (2003)
2.     Crowl D A, Louvar J F, “ Chemical Process Safety Fundamentals with applications”,
       2nd Prentice Hall, Englewood Cliffs (2002).
3.     Rao C S “Environmental Pollution Control Engineering”, McGraw Hill (1998 )
4.     Pandey G N and Carney G C,“Environmental Engineering” , McGraw Hill (1995 )
5.     Coulson J M and Richardson J F , “Chemical Engineering”,2nd , Vol 6, Pergamon
       Press (1999).

CB-405         Industrial Instrumentation                                              [2 0 0 2]

General principles of measurement.
Static and dynamic characteristics of instruments.
Temperature Measurement: Thermocouples, resistance thermometers, thermistors, optical
and radiation pyrometers.
Pressure Measurement: Use of manometers, Bourdon gauge, bellows type gauge,
measurement of vacuum and pressure transducers.
Flow Measurement: use of obstruction type meters. Variable area meters. Pressure probes,
positive displacement type meters.
Liquid level Measurement: Direct and differential method, measurement in open and
pressure vessels, measurement of liquid.
Measurement of Viscosity, Conductivity, Humidity and pH.
Measurement of nuclear radiation. Instrument for gas analysis, gas chromatography, mass
Industrial weighing and feeding systems.
Process instrumentation, recording instruments, indicating and signalling instruments,
transmission of instrument reading, control centre, instrumentation diagram, instrumentation
in modern plant.

Books Recommended

1.     Eckman D P, “ Industrial Instrumentation”, Wiley Eastern Ltd (1975).
2.     Kerk F W, Rimboi W, and Tarapore R, “Instrumentation”, Wiley and Sons (1983).
3.     Considine D N, “Process Instruments and Controls Handbook”, McGraw Hill (2001).
4.     Andrew W G,” Applied instrumentation in the Process Industries Vols I,II,III” Gulf
       Publishing Company (1987).
5.     Instrument Society of America Instrumentation in the chemical and petrochemical
       Industries Vol 8 (1984).

CB-410        Immunology                                                         [3 0 0 3]

Introduction       and Historical    Perspective: Innate and acquired immunity, major
components of immune system and their function, concept of antigen, antibody.
Cells and Organs of Immune System: Lymphoid cell, heterogenecity of lymphoid cells, T-
Cells, primary and secondary lymphoid organs- thymus, bursa of fabricus , spleen,
Lymphnodes, lymphatic system,, mucosal associated lymphoid tissue (MALT)
Humoral Immunity: B-lymphocytes and their activation , structure and function of
immunoglobulins, immnunologobulin classes and subclasses, genetic control and
production, monoclonal antibodies and diagnosis, major histocompatibility complex,
complement fixing antibodies and complement cascade
Cellular Immunity: Thymus derived lymphocytes (T-cells their classification antigen
presenting cells (APC), Macrophage their origin and function, mechanism of phagocytosis,
Identification of cell types of immune systems, immuno suppression and immune tolerance,
interferrons and their mechanism of action, interleukins and their functions.
Immunity and Infection: Hypersensitivity reactions, types and mechanisms of T Cell
activation, Cytokines and their role in immune response, transplantation and rejection, graft
rejection, Immunosuppressive drugs, mechanism of immunity, tumor antigens.
Immune Disorders and Diseases: Primary immuno deficiency,secondary immuno-
deficiency, Acquired immuno deficiency syndrome (AIDS)
Auto Immunity: Auto antibodies in humans, Pathogenic mechanisms, experimental models
of auto immune disease, treatment of autoimmune disorders.
Immunological Techniques and Vaccines: Precipitation, agglutination, RIA, ELISA,
Immunoelectrophoresis, Immunodiffusion

Books Recommended

1.     Kuby J “Immunology” , W.H. Freeman and Company, New York (2003)
2.     Roitt I M “Essentials of Immunology” , Blackwell Scientific Publications
       Oxford (1991)
3.     Benjamin E and Leskowity S “Immunology, A Short Course”, Wiley Liss (1991)
4.     Pelczar M J, Chan E C S and Krieg N R “Microbiology,”Mc Graw Hill, New York
5.     Pinchuk G, ”Schaum’s Outline of Immunology”,Tata McGraw Hill (2004)

CB-411        Food Biotechnology                                                 [3 0 0 3]

Introduction to Food Biotechnology :- Biotechnological processes in conventional and
non-conventional food, safety aspects, food industry wastes
Food Biotechnology Products :- Dairy products, cereal products, fruit and vegetable
products, meat and fish, food ingredients , High Fructose Corn Syrup , Mycoprotein etc.
Flavors and Pigments
Biotechnology and Food Preservation : Different techniques in food preservation,
canning, drying ,freezing encapsulation and controlled release of food components,
microwave food processing , super critical fluid extraction , accepting processing of food.
Genetically Modified and Transgenic Food: Development,processing , nutrition and
safety aspects.
Bioreactors in Food Biotechnology: Use of different bioreactors (e.g membrane
bioreactors) for various food productions, Modelling , simulation and optimization of
industrial processes, use of sensor and biosensors ,process control.

Books Recommended

1.     Angold ,Beech and Taggart “Food Biotechnology” , Cambridge University Press ,
       New York (1989)
2.     Schwartzberg H G and Rao M A “Biotechnology and Food Process Engineering”,
       Marcel Dekker ,IC (1990)
3.     Moo- Young Murray , “Comprehensive Biotechnology Vol. IV”, Pergamon Press New
       York (1985)
4.     Moo- Young Murray , “Comprehensive Biotechnology Vol. II”, Pergamon Press New
       York (1985)
5.     Reed G, “Prescott and Dunn’s Industrial Microbiology” CBS publishers and
       distributors, New Delhi (1987).

CB-412        Cell and Tissue Culture                                            [3 0 0 3]

Introduction : Special features and organization of plant cells, totipotency, regeneration of
plants, basic techniques in cell and tissue culture, culture media composition and
preparation, cell growth regulations
Cell Cultures : Initiation and maintenance of callus and suspension culture, protoplast
isolation, fusion and culture , somatic hybridization
Micropropagation : Techniques, factors affecting morphogenesis and proliferation rate ,
technical problems in micro propagation, meristem culture for the production of pathogen
free plants , applications of micro propagation,
Biochemistry of major metabolic pathways and products: Autotrophic and heterotrophic
growth – carbon dioxide assimilation, carbohydrate metabolism, nitrogen assimilation.
Plant products of industrial importance : Cell suspension culture development and
production of secondary metabolites by suspension cultures (case studies of azardiractin,
podophyllotoxin etc),
Biological and technology barriers : Mutation, somaclonal variation , hydrodynamic shear
and its quantification, mixing and impeller design aspects.
Plant Cell Reactors : Comparison of reactor performance , immobilized plant cell and cell
retention reactors.
Introduction: Cell and tissue culture media , media optimization (with and without serum )
and design asceptic techniques in tissue culture , cell metabolism and regulation, kinetics,
storage and preservation of cells, safety considerations in cell culture laboratory .
Cell culture : Monolayer culture , microcarrier culture and hybridoma technology ,
suspension cell cultures .
Animal Cell Bioreactors: Factors affecting mass transfer during growth of cells in culture,
criteria of scale up, use of perfusion and hollow fiber rector, harvesting and purification
methods for end product recovery .
Applications: Urokinase production, vaccines, monoclonal antibodies.

Books Recommended

1.     Bhojwani S S and Razdan M K,”Plant Tissue culture Theory and Practice”,
       Elesevier Science , Netherlands (2004)
2.     Narayanswamy S,”Plant Cell and Tissue culture”, Tata Mc-Graw Hill publishing Co.
       Ltd. (2002)
3.     Freshney R T, “Animal cell culture - A Practical approach”, Oxford University Press
4.     Spier R R and Griffiths J B,”Animal Cell Biotechnology”, Academics Press , London
5.     Butler, M “Mammalian Cell Biotechnology- A Practical Approach,” IRL Oxford
       University Press (1991)

CB-413        Downstream Processing                                             [3 0 0 3]

Role of downstream processing in biotechnology: role and importance, economics,
characterstics of biological mixtures, process design criteria for bioproducts, physico-
chemical basis of bio separation processes.
Primary separation and recovery processes: cell disruption method for intracellular
products, biomass separation techniques, flocculation and sedimentation, centrifugation and
filtration methods.
Enrichment operations: membrane separation, theory, design and configuration,
precipitation methods, extractive separation, aqueous 2-phase separation, in-situ product
Product resolution: adsorptive chromatographic separation processes, electrophoretic
separations, hybrid separation technologies
Product polishing: gel permeation chromatography, dialysis, crystallization

Books Recommended

1.     Wankat PC, “Rate Controlled Separations”, Elsevier (1990)
2.     Belter PA and Cussler E, Bioseparation , Wiley (1985)
3.     Asenjo J M, “ Separation Processes in Biotechnology”, 1993 Marcel Dekker Inc.
4.     Ladisch M R “ Bio Separation Engineering “, John Wiley and Sons (2002).
5.     John Garside , “ Separation Technology : The next ten years”, Institute of Chemical
       Engineers, U K.

CB-414        Polymer Technology                                                [3 0 0 3 ]

Introduction: Concepts and classification of polymers Functionality , Glass transition
temperature, Addition, condensation , step- growth and chain –growth polymerization
Molecular weight estimation: Average molecular weight – Number and weight average,
Sedimentation and viscosity average molecular weights, Molecular weight and degree of
polymerization, Significance of molecular weight.
Polymerization Processes: Bulk , solution, emulsion and suspension polymerization,
Comparison of polymerization processes.
Polymerization Kinetics: Chemistry of step reaction polymerization, Mechanism and
kinetics of polycondensation reactions and free- radical chain polymerization.
Synthetic Fibres: Types of Fibres, Spinning Techniques, Manufacturing Technology and
Applications of different types of fibres: cellulosic fibres, polyamides, acrylics, vinyls and
vinylidines, fluorocarbons.
Plastics: Manufacturing Technology and applications of different types of plastics:
Polyester, polyethylene, Phenolics, rubbers ,structure, properties and preparation natural
rubber synthetic rubbers: SBR, rubber compounding and reclaiming..

Books Recommended

1.     Gowariker V R , Viswanathan N V and Sreedhar J “Polymer Science” New Age
       International Publishers (1996)
2.     Billmeyer F W “Text Book of Polymer Science” Wiley Tappers (1994)
3.     Ghosh P, “Polymer Science and Technology of plastics and rubber” Tata McGraw
       Hill (2001).
4.     Gupta R K and Anil Kumar, “ Fundamentals of Polymer Engineering”, 2nd Ed., Marcel
       Dekkar (2003)
5.     Fried J R “Polymer Science and Technology” PHI

CB-415        Plant Utilities                                                      [3 0 0 3]

Steam :- Boilers- classification , various types, construction, boiler mountings & accessories,
properties of steam-tables, Mollier Diagram.
Power Generation :Internal Combustion Engines- classification, two- stroke, four stroke
petrol & diesel engine, valve timing diagram,carburetor, Combustion Phenomena .
Refrigeration: Air refrigeration cycles, vapour compression cycle, P-H diagram , liquification
processes .
Compressed Air and Vacuum :Use of compressed air. classification of compressors.
reciprocating compressors-mechanical details, single stage and two stage reciprocating
compressor , inter cooler, minimum work input in multistage.
centrifugal compressor- velocity diagram for centrifugal compressors, dimensional
parameters, slip factor , impeller blade shapes, losses in axial flow compressors.
Fuel : Natural gas, liquid petroleum fuels, coal &cCoke .
Waste Disposal : Plant sewer system and waste disposal .

Books Recommended

1.     Yadav R, “Thermodynamics & Heat Engines”, Central Publishing House.
2.     Vasandani, “Treatise on Heat Engines”
3.     Lyle O, “The efficient use of steam”,Her Majesty’s Stationary Ofiice,London (1968).
4.     Barrow H M, “ Preliminary Chemical Engineering Plant Design” New York
5.     Dodge B F, “Chemical Engineering Thermodynamics”, McGraw Hill

CB-416        Natural Gas Engineering                                              [3 0 0 3]

Gas from condensate and oilfields. Scope of Natural gas industry. Basic thermodynamic and
system energy concepts in Natural Gas Engineering.
Physical properties of natural gas and hydrocarbon liquids associated with Natural gas.
Phase behaviour studies of two phase hydrocarbon systems. Water-hydrocarbon system.
Vapour liquid equilibria.
Flow of fluids. Compression calculations. Heat Transfer and Mass Transfer principles and
applications in Natural Gas Engineering.
Gas flow measurement. Process control and instrumentation in natural gas processing
Natural Gas Processing. Field separation and oil absorption process. Refrigeration and low
temperature processing. Liquification process. Dehydration of Natural Gas sweetening of
Natural gas and sulphur recovery, Processing for LPG, LNG, CNG system.
Transmission of Natural Gas. Specifications. Utilization of Natural Gas. Underground storage
and conservation of Natural Gas.
Unconventional Gas: Coal Bed Methane, Natural Gas Hydrate.
Conversion of gas to liquid.

Books Recommended

1      Kumar S, “Gas Production Engineering”, Gulf Publishing Co. (1987)
2      Beggs H D, “Gas Production Operations”, OGCI Publication (1984).
3.     Ikoku C K, “Natural Gas Engineering” – John Wiley (1984).
4.     Alexandre R, “Natural Gas : Production, Processing and Transport” – Hyperion
       Books (1995).
5.     Donald L Katz, “Hand Book of Natural Gas Engineering” Mc Graw Hill

CB-417        Petroleum Recovery Technology                                       [3 0 0 3]

Physical and chemical characteristics of crude oil, origin of oil, source rock and maturation.
Migration of oil-mechanism pattern and barriers, Reservoir rocks and cap rocks, Entrapment
of oil-types and mechanism
Reservoir Rock Properties: Porosity, permeability, Effective and relative permeability,
wettability, capillary pressure characteristics.
Flow of fluids through porous media: Darcy’s law, single and multiphase flow.
Reservoir flow through porous media, drive mechanism, Introduction to enhanced oil
recovery methods.
Drilling: Introduction to on-shore and offshore drilling operations, drilling accessories rig
components, drilling fluid circulation system.
Production: Production equipment, Introduction to work over and well stimulation method.
Two phase oil and gas separation equipment, Types, their description, vessel internal sizing.
Theory of separation., Three phase oil- Gas and water separators- type of separators their
description, various control and vessel internals. LACT Units.
Storage and handling of Petroleum fluids: Different types of tanks for storage of oil and

Books Recommended

1.     Berger B D, Anderson K E, “Modern Petroleum” Pennwell books
2.     Bradley H B, “Petroleum Engineering Handbook”, SPE
3.     Cole F W, Reservoir Engineering manual
4.     Carl Gatlin , “Petroleum Engineering Drilling and Well Completions” Prentice Hall .
5.     Mc Cray and Cole , “ Oil Well Drilling Technology” Oklahoma Press .

CB-422        Chemical Process Control                                            [0 0 2 1]
              and Reaction Engineering Laboratory

1.     Study of rate constant for saponification reaction in constant strirred flow tank
2.     Study of rate constant for saponification reaction in Plug Flow Reactor
3.     Study of rate constant for saponifiction reaction in batch reactor
4.     Determination of rate constant in a packed bed reactor
5.     Study of RTD in a packed bed reactor
6.     Determination of time constant in liquid level tank
7.     Determination of time constant in a heated tank
8.     To study the effect of proportional controller in a liquid level tank
9.     To study the effect of proportional Integral controller in a liquid level tank
10.    To study the effect of proportional – Integral and derivative controller in a liquid
       level tank.

       Note : At least 8 experiments to be performed.

CB-423         Process Modeling and Simulation Laboratory                             [0 0 4 2]

Principles of formulation of mathematical models , Fundamental laws , continuity equation ,
energy equation , Equation of motion , Transport equation, Equation of state, Equilibrium ,
Chemical kinetics, Lumped parameter model, distributed parameter models .
Modeling & Simulation of various Chemical Engineering systems like isothermal CSTR, non-
isothermal CSTR , Isothermal batch reactor , non –isothermal batch reactor, Heat
exchangers, etc.

Books Recommended

1.     Luyben W L , “Process Modelling Simulation and Control for Chemical Engineers”,
       international ed. McGraw Hill (1990).
2.     Rose L M, “ The Application of Mathematical Modelling to Process Development and
       Design”, First Ed. Applied Science Publisher Limited., London (1974).
3.     Bequette , “ Process Dynamics- Modelling, Analysis and Simulation”, PHI
       International (2003).
4.     Rase H F, “Chemical Reactor Design for Process Plants, Vol II: Case Studies and
       Design Data”, 1st Ed., John Wiley and Sons, New York (1997)
5.     Denn M Morton, “ Process Modelling”, First Ed. Longman Publisher (1986).

CB-424         Environmental Engineering Laboratory                                   [0 0 2 1]

1.     To determine the Total Solids of a given sample.
2.     To find out Total Dissolved Solids of a given sample.
3.     To find out Fixed and Volatile solids of the given sample.
4.     To determine Acidity ( base capacity ) of the given sample.
5.     To determine the Alkalinity of the given sample.
6.     To determine the Total Hardness of the given sample.
7.     To find out amount of Sulphates in a given sample .
8.     To estimate the content of Chlorides in the given water sample
9.     To find the quantity of the Dissolved Oxygen present in the given sample
10.    To determine the BOD of a given waste water sample.
11.    To determine the COD of a given waste water sample.

CB-427         Colloquium                                                             [0 0 2 1]

Every student has to present the seminar on the assigned topic by the department . The
student will be required to submit one copy of the report.

OC/CB-332      Energy Technology                                                      [3 0 0 3]

Solid Fuels : Principle Solid Fuels – Coal, origin , composition & classification of coal,
properties of coal , terms used in analysis of coal, classification of Indian coals , petrology of
Coal Preparation : Dry and Wet processes, storage of coal. Coal carbonisation :
mechanism of carbonisation , high temperature and low temperature carbonization
briquetting, gasification of coal, liquefaction of solid fuels.
Liquid Fuels: Petroleum and related products,origin, occurrence and reserves, nature of
petroleum crudes, classification and characteristics of petroleum, Refining Unit Process:
Cracking, Thermal Cracking ,Catalytic cracking , Hydrocracking, Reforming Thermal and
Catalytic Reforming, Alkylation, Polymerization Isomerization, petroleum products :naphtha,
motor gasoline, aviation gasoline , kerosene , diesel oil, gas oil , fuel oil , lubricants ,
petroleum waxes,petroleum coke.
Gaseous Fuels: Classification, natural gas, methane from coal mines, producer, water,
carbureted water gas , coal, blast furnace , refinery gases , LPG.
Alternate Energy Systems: Solar Energy, Nuclear energy, wind energy, tidal energy,
geothermal energy .

Books Recommended

1.     Brame J S and King J C, “Fuels- Solid, Liquid and Gaseous” , St. Martin Press
2.     Sarkar S, “Fuels and combustion” , Longman publishers India Ltd.., IInd Edition
3.     Haslam R T and Russel R P, “Fuels and their combustion” , McGraw Hill.
4.     Gupta O P ,“Elements of Fuels , Furnaces and Refractories”, Khanna Publishers.
5.     Griswold J, “Fuels combustion and furnaces”, McGraw Hill

OC/CB-431      Basic Biotechnology                                                  [3 0 0 3]

Introduction to Life : Characteristics of Living Organisms, molecular basic of Life, structure
and function of prolaryotic and eukaryotic cell.
Structure and Function of Macromolecules : Carbohydrates, Lapids , proteins, nucleic acid,
enzymes as biocatalysts.
Biotechnology: Definition & history, fields of biotechnology, importance and achievement
of biotechnology; biological process and Chemical processes their advantages and
disadvantages , safety aspects of biotechnology.
Genetic Engineering and Biotechnology :Definition , tools of genetic engineering ,
applications, bioinformatics.
Biotechnology and Medicine :Pharmaceuticals and biopharmaceuticals, antibiotics,
vaccines and monoclonal antibodies, gene therapy.
Biotechnology and Environment : Microbial ecology, role of m microbes in waste water
and sewage treatment, mineral leaching , bioremediation .
Plant and Animal biotechnology: Animal Requirements for plant and animal cell and tissue
culture, substrates for cell culture, biotechnological application of plant cell and animal cell
Microbial and Food biotechnology : Role of microbes and enzyme for different
industrial products , enzyme and food processing.

Books Recommended

1.     Pelczar M J, Chan E C S and Krieg N R, “ Microbiology”, McGraw Hill , New York
2.     Lehninger A L, Nelson D L , “ Principles of Biochemistry” , CBS Publishing and
       Distributors , New Delhi ( 1993 )
3.     Smith J E, “ Biotechnology”, Cambridge Univeristy Press ( 1996)
4.     Dubey R C , “ A text book of Biotechnology ”, S Chand and Company Ltd., New
       Delhi ( 2001)
5.     Rajeshwari S Setty, and V Sreekrishna , “Biotechnology”, New Age International
       Publisher, New Delhi (2003)
(Courses Offered by other departments)
MA-200         Numerical Methods                                [3 1 0 4]

Approximation and Errors: Accuracy of numbers, Errors in approximations, Order of
approximation and Propagation of errors.
Roots of Algebraic and Transcendental Equations: Bisection method, Regula-falsi
method, Iteration method, Newton-Raphson method, Bairstow’s method and Graeffe’s root
squaring method.
Solution of Simultaneous Algebraic Equations, Matrix Inversion and Eigen-value
Problems: Triangularisation method, Jacobi’s and Gauss-Siedel iteration methods, Newton-
Raphson method for nonlinear simultaneous equations, Triangularisation method for matrix
inversion, Partition method for matrix inversion, Power method for largest eigen-values and
Jacobi’s method for finding all eigen-values.
Finite Differences Interpolations and Numerical Differentiations: Forward, Backward,
Central differences and relations between them, Newton’s forward, backward and divided
difference interpolation formulas, Lagrange’s interpolation formula, Stirling’s and Bessel’s
central difference interpolation formulas, Numerical differentiations using Newton’s forward
and backward difference formulas and Numerical differentiations using Stirling’s and
Bessel’s central difference interpolation formulas.
Numerical Integrations: Trapezoidal rule, Simpson’s one-third rule and Numerical double
integrations using Trapezoidal rule and Simpson’s one-third rule.
Numerical Solution of Differential Equations
Ordinary Differential Equations: Taylor’s series method, Euler’s and modified Euler’s
methods, Runge-Kutta fourth order methods, methods for solving simultaneous first order
differential equations and methods for solving second order differential equations.
Boundary Value Problems: Finite difference methods for Boundary Value Problems
Partial Differential Equations: Finite difference methods for Elliptic, Parabolic and
Hyperbolic equations

Books Recommended

1.     Sastry S S, “Introductory Methods of Numerical Analysis”, 3rd Ed. Prentice Hall of
       India Pvt. Limited , New Delhi, 1999.
2.      Schilling R J, Harries S L, “Applied Numerical Methods for Engineers( Using
       MATLAB and C)”, Thomsan Asia Pvt. Limited, Singapore, 2002
3.      Gerald C F, Wheatley P O, “ Applied Numerical Analysis”, 5th Ed (First ISE Reprint)
       Addison –Wesley Publishing Company, 1998.
4.      Chapra S C, Canale R P, “ Numerical Methods for Engineers”, 2nd Ed., McGraw
       Hill, Singapore , 1990.
5.      Gupta S K, “ Numerical Methods for Engineers”, Ist Edition, New Age International
       Private Limited, New Delhi, 1998.

MA 202                Optimization Techniques                    [ 3 0 03]

Linear Programming Problem: Simplex method of linear programming technique.
Engineering applications of optimization. Design variables, constraints, objective function,
variable bounds, statement and formulation of an optimization problem. Examples of
Chemical Engineering optimization problems, classification of optimization problems,
different optimization algorithms. Optimal point, local optimal point, global optimal point and
inflection point.
Single Variable Optimization Techniques: Optimality criterion, Bracketing method-
Bounding phase method. Region elimination methods- internal halving method, Golden
section search method. Point estimation method-             successive quadratic estimation
method.Gradient based method - Newton-Raphson method, Bisection method, Secant Cubic
search method. Root finding using optimization techniques.
Multivariable Optimization Techniques: Optimality criterion, Unidirectional search method,
Direct search method - Hooke-Jeeves pattern search method, Powell’s conjugate direction
method.Gradient based methods -Steepest descent method, Newton’s Method, Marquardts
Constrained Optimization Algorithms: Kuhn-tucker conditions, Transformation method -
penalty function method. Direct search for constrained minimization - Variable elimination
method. Complex search method.

Books Recommended:

1.     Deb Kalyanmoy., “Optimization for Engineering DesignAlgorithms and
       Examples”, Prentice-Hall of India, New Delhi, 2003.
2.     Hadley G, “Non-linear and Dynamic Programming”, Addison Wesley, New York,
3.      Rao S S, “Optimization Theory and Applications” , Wiley Eastern, New Delhi,
4.     Reklaitis G V, Ravindran A and Ragsdell K M, “ Engineering Optimizations 
       Methods and Applications “, Wiley, New York, 1983.
5.     Taha H A, “Operations Research” , MacMillan, New York, 2003.

     MA 202   Optimization Techniques Laboratory               [0 0 21]

1.     Simplex method
2.     Bounding phase method
3.     Golden section search method.
4.     Successive quadratic estimation method.
5.     Steepest descent method.
6.     Marquardt’s method.
7.     Powell’s conjugate direct method.
8.     Penalty function method.
9.     Variable elimination method.

PH 204                        Material Science and Engineering            [ 3   1   0   4]

Structure of crystalline Solids: Crystal structures and crystal system, reciprocal lattice,
miller indices, closed packed structures, determination of crystal structures.
Imperfections in solid: Point imperfections and their equilibrium concentration, Edge and
screw dislocations; burgers vector and the dislocations; burgers vector and the dislocation
leap, stress fields and energies of dislocations, dislocations forces, dislocation sources;
Multiplication of dislocations.
Diffusion in Solid : Fick’s law of diffusion, solution to fick;s second law, applications based
on second law solution , the kirkendall effect, the atomic model of diffusion.
Mechanical properties: The elastic properties, model of elastic Behaviour, platic
deformation tensile stress-strain curve, shear strength of perfect and real crystals,
mechanical failure, fatigue and fracture, creeps: mechanism of creep, Characterization of
creep curves.
Electrical properties : Classical and quantum theory of free electronics; relaxtion time,
collision time and mean free path, density of energy states and Fermi energy, Electorn
motion under periodic potential , Origin of energy bands in solids, classification of material
on the basis of band gap, effective mass, intrinsic and extrinsic semi- conductors, hall effect
and its applications.
Dielectric properties: Mechanism of polarization, concept of polarizability and internal
fields, Dielectrics in alternating fields; frequency of dependence of polarizability.
Magnetic properties : Magnetic moments and its origin, dia- and para- magnetism, ferro
and ferri- magnetism, soft and hard magnetic materials , ferrites , Application of magnetic
Super conductivity : Properties          of superconductors. London equations, quantum
explanation of super conductivity, flux quantization, application of super conductors.

Books Recommended

1.     William D. Callister, Jr. “Materials Science and Engineering” John Wiley and Sons,
       Inc. New York , 1997
2.     Dekker A.J. , “Solid State Physics” Macmillan, India Limited , Madra, 1991.
3.     Azaroff. L.V “ Introduction to Solid”, Tata Mc Graw Hill , New Delhi, 1992
4.     RaghvanV. “ Material Science and Engineering “, Prentice Hall of India, New Delhi,
5.     Kittal “Solid State Physics” Wiley Eastern Limited, New Delhi, 1987

PH 224     Material Science and Engineering Laboratory            [0 0 2 1]

1.     To determine the resistivity of a semiconductor by four –probe method.
2.     To estimate the band gap energy of seminconductor .
3.     To determine the Hall coefficient of a semiconductor and hence to estimate the
       charge carrier concentration
4.     To calibrate an electromagnet
5.     To determine the magnetic susceptibility of paramagnetic salt by Guoy’s balance
6.     To find energy loss due to hysteresis for the material of given metal ring using a
7.     To investigate creep of a copper wire at room temperature .
8.     To find young’s modulus , modulus of rigidity and Poisson’s ratio for the material of a
       given wire by Searle’s method.
9.     To study the elastic behaviour of solid using composite Piezo- electro oscillator .
10.    To study cooling curve a binary alloy
11.    To test the given cement sample using autocalve
12.    To determine the permittivity of a given material using parallel capacitor
13.    To verify Richerdson’s equation of thermionic emission
14.    To study the magnetization and de-magnetization behaviour of ferromagnetic rod
       by magnetometer method.

                                          THE HONOUR CODE

I____________________________, Registration no.______________ do hereby
undertake that as a student at Dr B R Ambedkar NIT Jalandhar:

(1)     I will not give or receive aid in examinations; that I will not give or receive
        unpermitted aid in class work, in preparation of reports, or in any other work
        that is to be used by the instructor as the basis of grading; and
(2)     I will do my share and take an active part in seeing to it that others as well as
        myself uphold the spirit and letter of the Honour Code.
I realize that some examples of misconduct which are regarded as being in violation of
the Honour Code include:
       copying from another’s examination paper or allowing another to copy from one’s
        own paper;
       unpermitted collaboration;
       plagiarism;
       revising and resubmitting a marked quiz or examination paper for re-grading
        without the instructor’s knowledge and consent;
       giving or receiving unpermitted aid on take-home examinations;
       representing as one’s own work the work of another, including information
        available on the internet; and
       giving or receiving aid on an academic assignment under circumstances in which a
        reasonable person should have known that such aid was not permitted.
       committing a cyber offence, such as, breaking passwords and accounts, sharing
        passwords, electronic copying, planting viruses etc.
I accept that any act of mine that can be considered to be an Honour Code violation will
invite disciplinary action.
Date ________________             Student’s Signature _____________________________
                                  Entry no.______________________________________
Submit one signed copy at Registration
Keep one signed copy with you
Keep one signed copy with your parent(s)/guardian

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