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Weekly Report Narrative 842009

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Weekly Report Narrative 842009
UW Weekly Recovery Act Report

Summary: The week of July 27th August 2nd 2009, the University of Washington

received 26 ARRA awards for $10, 271, 983 Million. This brought total awards to

date to 99 awards for $38,263,527 Million. Expenditures to date are $284,869.00.



Thirty (38) of the awards are from the National Science Foundation, 58 from the

National Institutes of Health, 1 from the State of Washington, 1 from PNNL and 1

from the National Endowment for the Arts.



Research Highlights:



Multisite Prevention of Adolescent Conduct Problems

PI Robert McMahon Sponsor NIH



This 10 year long comprehensive intervention study will

Evaluate almost 1400 youth from kindergarten through age 20. The research is designed

to prevent serious antisocial behavior and related adolescent problems and examine

developmental models of conduct problems through childhood and adolescence. Youth

have been followed annually from kindergarten through age 20. The research plan

focuses on two issues identified as central for advancing knowledge about conduct

problems. The first issue concerns the age-of-onset subtyping approach to identifying

developmental pathways of conduct problems and the diagnosis of conduct disorder. (The

second issue concerns the potential role of psychopathic traits in identifying an additional

developmental pathway of conduct problems.



Mediated Shedding in Endothelial Inflammatory Responses

PI Elaine W Raines Sponsor NIH



Activation of the endothelial cells that line blood vessels during inflammatory processes

such as those associated with cardiovascular disease results in the recruitment of

circulating white blood cells into the vessel wall. This situation can ultimately contribute

to blockage of the blood vessel. One potentially important mechanism for endothelial

cells to regulate the recruitment of white blood cells is to rapidly modulate their

repertoire of cell surface proteins through proteolytic "shedding". The long-term

objective of this research is to better understand the cellular and molecular mechanisms

controlling chronic inflammatory responses such as atherosclerosis that remains the

major cause of death in the Western world.

Clinical Nutrition Research Unit

PI Alan Chait

Sponsor NIH



The major goal of the Clinical Nutrition Research Unit (CNRU) at the University of

Washington is to promote and enhance interdisciplinary nutrition research by bringing

together basic science and clinical investigators on a cooperative basis.



Elementary Particle Physics Using High Energy Colliders

PI Henry J Lubatti Sponsor NSF



The start of the Large Hadron Collider Program at CERN laboratory in Geneva,

Switzerland opens up a rich physics opportunity for fully exploring the mass energy

region up to 1 TeV. The goal of our research program is to significantly extend our

understanding of the Standard Model and go beyond the Standard Model boson. In the

early years of the LHC operation the research will focus on the observation and search

for long-lived heavy particles. The prospects for new discoveries that will significantly

increase our understanding of the fundamental forces of nature are enormous.


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