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LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/02/2009



Clamp : 15 mn ; Frozen procedure : 24 mn ; T : 39 mn



Patient : N°LH 09-0215 N°LB 09-0072 ID : FE MA

Consent : YES

Diagnosis and staging : inflammatory excaved lesion with few

Age : 57 degenerative aspergillus

Diagnosis of frozen specimens : inflammatory parenchyma

Sex : F





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 4.5 x 3.5 cm Location : left upper lobe

Location : left upper lobe Histology : mild alveolitis



2D- Specimens for diagnosis :

1D- Specimens for diagnosis : Weights : D1 : 163 mg, D2 : 188 mg

Weights : D1 : 60 mg, D2 : 171 mg 2R- Specimens for research : Nb : 5

1R- Specimens for research : Nb : 5 Weights : R1 : 212 mg, R2 : 141 mg, R3 : 331

Weights : R1 : 74 mg, R2 : 116 mg, R3 : 45 mg, R4 : 308 mg, R5 : 366 mg

mg, R4 : 84 mg, R5 : 112 mg



4- Controls of quality

RNA (quality and quantity available)





Infection : YES (aspergillus)

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :







S P C ctDNA









Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/02/2009



Clamp : 35 mn ; Frozen procedure : 20 mn; T : 55 mn



Patient : N°LH 09-0219 N°LB 09-0076 ID : IB PE

Consent : YES

Diagnosis and staging : squamous cell carcinoma pT1N0MX

Age : 60

Diagnosis of frozen specimens : well differentiated squamous

Sex : M cell carcinoma





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 2.1 x 1.7 cm Location : dorsal

Location : bronchial proximal right upper lobe Histology : alveolitis



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 108 mg, D2 : 83 mg Weights : D1 : 370 mg, D2 : 430 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 128 mg, R2 : 141 mg, R3 : 44 Weights : R1 : 281 mg, R2 : 573 mg, R3 : 228

g, R4 : 67 mg, R5 : 85 mg mg, R4 : 356 mg, R5 : 520 mg



Percent of tumor cells : 30 %

4- Controls of quality

RNA (quality and quantity available)





Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock : 2008-6C







S P C ctDNA



x3



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/03/2009



Clamp : 20 mn ; Frozen procedure : 17 mn; T : 37 mn



Patient : N°LH 09-0221 N°LB 09-0077 ID : CL AN

Consent : YES

Diagnosis and staging : basaloid carcinoma pT2N0MX

Age : 67

Diagnosis of frozen specimens : basaloid carcinoma

Sex : F





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 1.7 x 1.6 cm Location : middle lobe

Location : middle lobe Histology : emphysema



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 77 mg, D2 : 79 mg Weights : D1 : 137 mg, D2 : 132 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 96 mg, R2 : 86 mg, R3 : 59 Weights : R1 : 156 mg, R2 : 175 mg, R3 : 155

mg, R4 : 56 mg, R5 : 28 mg mg, R4 : 199 mg, R5 : 314 mg



Percent of tumor cells : 70 %

4- Controls of quality

RNA (quality and quantity available)





Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock : 2008-6C







S P C ctDNA





x1



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/03/2009

Time for frozen procedure : 25 mn





Patient : N°LH 09-0229 N°LB 09-0078 ID : PO MA

Consent : YES NO

Diagnosis and staging : lung hamartoma

Age : 55

Diagnosis of frozen specimens : hamartoma

Sex : M





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 1.7 x 1.2 cm

Location : right lower lobe None

1D- Specimens for diagnosis :

Weights : D1 : 166.8 mg, D2 : 112 mg

1R- Specimens for research : Nb : 2

Weights : R1 : 155 mg, R2 : 125 mg







4- Controls of quality

RNA (quality and quantity available)





Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :

Not available



S P C ctDNA





x6



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/04/2009



Patient : N°LH 09-0239 N°LB 09-0081 ID : TU MI

Consent : YES

Diagnosis and staging : post chimiotherapy sterilised bronchic

Age : 74 tumor ypT0N0M0



Sex : M









Infection : NO

For diagnosis bank : NO









Destock :









S P C ctDNA



x8

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : S. LASSALLE

CHEST 02/05/2009



Patient : N°LH 09-0242 N°LB 09-0082 ID : CO DA

Consent : YES

Diagnosis and staging : mediastinal lymph node with tumoral

Age : 74 necrosis without residual metastasis



Sex : M









Infection : NO

For diagnosis bank : NO









Destock :









S P C ctDNA



x4

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : S. LASSALLE

CHEST 02/05/2009



Clamp : 25 mn ; Frozen procedure : 60 mn; T : 85 mn



Patient : N°LH 09-0248 N°LB 09-0083 ID : ME MA

Consent : YES

Diagnosis and staging : well differenciated squamous cell

Age : 61 carcinoma (grade 2). pT1N0Mx

Diagnosis of frozen specimens : squamous cell carcinoma

Sex : F





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 2 cm Location : right upper lobe

Location : right upper lobe Histology : normal



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 107 mg, D2 : 116 mg Weights : D1 : 145 mg, D2 : 199.5 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 51.2 mg, R2 : 91 mg, R3 : 38.2 Weights : R1 : 180 mg, R2 : 183 mg, R3 :

mg, R4 : 62 mg, R5 : 52.3 mg 166.5 mg, R4 : 147 mg, R5 : 192 mg



Percent of tumor cells : 60 %

4- Controls of quality

RNA (quality and quantity available)





Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :2008-6C







S P C ctDNA





x2



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/09/2009



Patient : N°LH 09-0255 LB

N° 09-0084 ID :GO GE

Consent : NO

Diagnosis and staging : emphysema

Age : 60





Sex : M









Infection : NO

For diagnosis bank : NO









Destock :









S P C ctDNA





x3

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/09/2009



Patient : N°LH 09-0264 N°LB 09-0085 ID : GI AL

Consent : YES

Diagnosis and staging : post radio and chimiotherapy lung

Age : 69 metastasis of squamous cell carcinoma : no residual tumor



Sex : M









Infection : NO

For diagnosis bank : NO









Destock :









S P C ctDNA



x4

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : V. HOFMAN

CHEST 02/10/2009

Time for frozen procedure : 15 mn





Patient : N°LH 09-0266 N°LB 09-0086 ID : MA GI

Consent : YES

Diagnosis and staging : desmoplastic malignant mesothelioma

Age : 73 T3NXMX (advice mesopath)

Diagnosis of frozen specimens : desmoplastic malignant

Sex : M mesothelioma





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : pleural decortication 9 cm

Location : right parietal pleura None

1D- Specimens for diagnosis :

Weights : D1 : 215 mg, D2 : 114 mg

1R- Specimens for research : Nb : 5

Weights : R1 : 104 mg, R2 : 118 mg, R3 : 195

mg, R4 : 119 mg, R5 : 166 mg



Percent of tumor cells : 30 %

4- Controls of quality

RNA (quality and quantity available)





Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :

Not available



S P C ctDNA





x5



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : CH. MARQUETTE

CHEST 02/10/2009

PNEUMO

Patient : N°12 LB

N° 09-0087 ID : GU RA

Consent : YES NO

Diagnosis and staging : PHRC

Age : 67





Sex : M









Infection : YES NO

For diagnosis bank : YES NO









Destock :









S P C ctDNA





x7

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : CH. MARQUETTE

CHEST 02/11/2009

PNEUMO

Patient : N°13 LB

N° 09-0090 ID : JU IL

Consent : YES NO

Diagnosis and staging : PHRC

Age : 76





Sex : M









Infection : YES NO

For diagnosis bank : YES NO









Destock :









S P C ctDNA





x9

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/16/2009

Time for frozen procedure : 10 mn





Patient : N°LH 09-0299 N°LB 09-0095 ID : GR DI

Consent : YES

Diagnosis and staging : mediastinal lymph node metastasis of

Age : 50 mixed sub type pulmonary adenocarcinoma

Diagnosis of frozen specimens : mixed sub type

Sex : M adenocarcinoma





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 1.1 cm

Location : right site 4 None

1D- Specimens for diagnosis :

Weights : D1 : 37 mg

1R- Specimens for research : Nb : 3

Weights : R1 : 74 mg, R2 : 47 mg, R3 : 22 mg



Percent of tumor cells : 50 %



4- Controls of quality

RNA (quality and quantity available)





Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :

Not available



S P C ctDNA









Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : CH. MARQUETTE

CHEST 02/17/2009

PNEUMO

Patient : N°14 LB

N° 09-0098 ID : LU RO

Consent : YES NO

Diagnosis and staging : PHRC

Age : 55





Sex : M









Infection : YES NO

For diagnosis bank : YES NO









Destock :









S P C ctDNA

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : CH. MARQUETTE

CHEST 02/17/2009

PNEUMO

Patient : N°15 LB

N° 09-0099 ID : LY JE

Consent : YES NO

Diagnosis and staging : PHRC

Age : 69





Sex : M









Infection : YES NO

For diagnosis bank : YES NO









Destock :









S P C ctDNA

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/17/2009

Time for frozen procedure : 20 mn





Patient : N°LH 09-0311 N°LB 09-0100 ID : GA JE

Consent : YES

Diagnosis and staging : esophagal intramural bronchogenic cyst

Age : 63

Diagnosis of frozen specimens : bronchogenic cyst

Sex : M





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 4.5 cm Location : esophagus

Location : lower esophagus Histology : normal mucosa



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 46 mg, D2 : 27 mg Weights : D1 : 72 mg, D2 : 87 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 54 mg, R2 : 95 mg, R3 : 77 Weights : R1 : 51 mg, R2 : 73 mg, R3 : 72 mg,

mg, R4 : 46 mg, R5 : 52 mg R4 : 152 mg, R5 : 136 mg







4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :







S P C ctDNA







Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/18/2009

Time for frozen procedure : 15 mn





Patient : N°LH 09-0315 N°LB 09-0101 ID : BE RE

Consent : YES

Diagnosis and staging : malignant epithelioid mesothelioma

Age : 74 TXNXMX

Diagnosis of frozen specimens : malignant epithelioid

Sex : M mesothelioma





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 7 cm

Location : parietal pleura None

1D- Specimens for diagnosis :

Weights : D1 : 88 mg, D2 : 196 mg

1R- Specimens for research : Nb : 5

Weights : R1 : 262 mg, R2 : 202 mg, R3 : 212

mg, R4 : 177 mg, R5 : 205 mg



Percent of tumor cells : 5 %

4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :

Not available



S P C ctDNA



x6



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : S. LASSALLE

CHEST 02/19/2009



Clamp : 18 mn ; Frozen procedure : 50 mn T : 68 mn



Patient : N°LH 09-0325 N°LB 09-0102 ID : AR FA

Consent : YES

Diagnosis and staging : squamous cell carcinoma basaloid

Age : 53 variant (grade 4). pT2N1Mx

Diagnosis of frozen specimens : squamous cell carcinoma

Sex : M basaloid variant





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 4.5 cm Location : left lower lobe

Location : left upper lobe Histology : alveolitis



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 88 mg, D2 : 93 mg Weights : D1 : 297 mg, D2 : 331 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 290 mg, R2 : 166 mg, Weights : R1 : 256 mg, R2 : 335 mg,

R3 : 267 mg, R4 : 119 mg, R5 : 150 mg R3 : 241 mg, R4 : 272 mg, R5 : 262 mg



Percent of tumor cells : 60 %

4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :







S P C ctDNA



x6



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : S. LASSALLE

CHEST 02/20/2009

Time for frozen procedure : 15 mn





Patient : N°LH 09-0340 N°LB 09-0105 ID : GR ER

Consent : YES

Diagnosis and staging : thymic carcinoma (type C thymoma)

Age : 46

Diagnosis of frozen specimens : thymic carcinoma

Sex : M





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 9 cm

Location : thymus None

1D- Specimens for diagnosis :

Weights : D1 : 167 mg, D2 : 77 mg

1R- Specimens for research : Nb : 5

Weights : R1 : 180 mg, R2 : 120 mg, R3 : 168

mg, R4 : 182 mg, R5 : 239 mg



Percent of tumor cells : 40 %

4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :

Not available



S P C ctDNA







Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/23/2009



Clamp : 15 mn ; Frozen procedure : 50 mn ; T : 65 mn



Patient : N°LH 09-0345 N°LB 09-0106 ID : MA PA

Consent : YES

Diagnosis and staging : mixed sub type adenocarcinoma

Age : 67 pT4N2MX

Diagnosis of frozen specimens : mixed sub type

Sex : M adenocarcinoma



1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 7 x 5 cm Location : right lower lobe

Location : right upper lobe Histology : alveolitis



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 69 mg, D2 : 112 mg Weights : D1 : 280 mg, D2 : 258 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 102 mg, R2 : 165 mg, R3 : Weights : R1 : 354 mg, R2 : 320 mg, R3 : 411

137 mg, R4 : 48 mg, R5 : 250 mg mg, R4 : 306 mg, R5 : 361 mg



Percent of tumor cells : 35 % 4- Controls of quality

RNA (quality and quantity available)

Lesion : R1 rRNA 28S/18S: 0.6

:

C° 0.10703µg/µl Tot qty : 4.71µg





Infection : NO rRNA 28S/18S: 1

For diagnosis bank : YES :

C° 0.054µg/µl Tot qty : 2.4 µg

Perilesion : R4





3- Morphological controls (mirrors) :

DNA (quality and quantity available)

Lesion :

- C°: 0.16862 µg/µl ; Tot qty : 32.54 µg

- DO 260/280 : 1.99 ; PCR GAPDH : OK

Perilesion :

- C°: 0.13094 µg/µl ; Tot qty : 25.27 µg

- DO 260/280 : 2.01 ; PCR GAPDH : OK

Destock : BIOBANK 2008-6 c.G







S P C ctDNA



x2



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : CH. MARQUETTE

CHEST 02/23/2009

PNEUMO

Patient : N°16 LB

N° 09-0107 ID : SC PI

Consent : YES NO

Diagnosis and staging : PHRC

Age : 75





Sex : M









Infection : YES NO

For diagnosis bank : YES NO









Destock :









S P C ctDNA





x6

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/23/2009

Time for frozen procedure : 15 mn





Patient : N°LH 09-0348 N°LB 09-0108 ID : CI BR

Consent : YES

Diagnosis and staging : mediastinal recurrent liposarcoma grade

Age : 64 1 FLNCC

Diagnosis of frozen specimens : well differentiated lipoma like

Sex : M and sclerosing with focal myxoid area





1- Lesional tissue specimens

Size : 10 cm

Location : anterior mediastinum



1D- Specimens for diagnosis :

Weights : D1 : 386 mg, D2 : 333 mg

1R- Specimens for research : Nb : 5

Weights : R1 : 291 mg, R2 : 196 mg,

R3 : 276 mg, R4 : 262 mg, R5 : 472 mg



Percent of tumor cells : 100 %

4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : YES





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :

Not available



S P C ctDNA







Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : C. BUTORI

CHEST 02/24/2009

Time for frozen procedure : 35 mn





Patient : N°LH 09-0352 N°LB 09-0109 ID : MA PA

Consent : YES

Diagnosis and staging : nodular amyloidosis

Age : 75

Diagnosis of frozen specimens : nodular amyloidosis

Sex : M





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 2.5 cm Location : perilesional

Location : right lower lobe Histology : alveolitis



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 69 mg, D2 : 90 g Weights : D1 : 114 mg, D2 : 165 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 110 mg, R2 : 104 mg, R3 : 95 Weights : R1 : 153 mg, R2 : 142 mg, R3 : 109

mg, R4 : 63 mg, R5 : 130 mg mg, R4 : 88 mg, R5 : 89 mg







4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : NO





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock :







S P C ctDNA







Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : S. LASSALLE

CHEST 02/26/2009



Clamp : 50 mn ; Frozen procedure : 90 mn ; T : 140 mn



Patient : N°LH 09-0373 N°LB 09-0111 ID : CO JE

Consent : YES

Diagnosis and staging : mixed subtype adenocarcinoma T2N0MX

Age : 62

Diagnosis of frozen specimens: poorly differentiated mixed

Sex : M subtype adenocarcinoma





1- Lesional tissue specimens 2- Perilesional tissue specimens

Size : 10.5 x 10.5 cm Location : dorsal segment

Location : right upper lobe Histology : alveolitis and emphysema



1D- Specimens for diagnosis : 2D- Specimens for diagnosis :

Weights : D1 : 180 mg, D2 : 234 mg Weights : D1 : 113 mg, D2 : 133 mg

1R- Specimens for research : Nb : 5 2R- Specimens for research : Nb : 5

Weights : R1 : 458 mg, R2 : 342 mg, R3 : 238 Weights : R1 : 287 mg, R2 : 218 mg, R3 : 321

mg, R4 : 249 mg, R5 : 239 mg mg, R4 : 222 mg, R5 : 216 mg



Percent of tumor cells : 70 %

4- Controls of quality

RNA (quality and quantity available)



Infection : NO

For diagnosis bank : YES





3- Morphological controls (mirrors) : DNA (quality and quantity available)









Destock : 2008-6 c.G







S P C ctDNA



x5



Lesion Perilesion

LPCE / CHU Unit

BIOBANK LPCE-NICE

Pathologist : S. LASSALLE

CHEST 02/27/2009



Patient : N°LH 09-0385 N°LB 09-0115 ID : VI JE

Consent : YES

Diagnosis and staging : lung metastasis of digestive

Age : 60 adenocarcinoma (T2NXM1)



Sex : M









Infection : NO

For diagnosis bank : NO









Destock :









S P C ctDNA





x5



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