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American Laboratory Products Company PO Box 451 • Windham, NH 03087 Tel.(800)592-5726 • Fax.(603)898-6854 www.alpco.com MOC-31 (Lung Cancer Marker) Code: 13-2222MOC-31 SPECIES: Mouse Monoclonal; Hybridoma's: Mouse myeloma X 63-BALB/c CLONE: MOC-31 Ig CLASS: IgG1 REAGENT: Culture Supernatant IMMUNOGEN: Small cell lung carcinoma derived cell line preparation. CLINICAL APPLICATION: This antibody is reactive with all lung carcinomas and most epithelia. MOC-31 is unreactive with normal and malignant mesothelia and therefore especially useful for the detection of carcinoma cells in ascites or pleural effusions. Immunoblotting: MOC-31 (Cluster 2 antibody) is directed against a membrane associated protein of 40 kD LOCALIZATION: Membrane APPLICATION: Frozen sections / Cell preparations Paraffin sections: * * No pretreatment * Microwave oven / Autoclave: * Protease Digestion Trypsin: POSITIVE CONTROL: Brain / adrenal gland CONTENTS: 1.0 ml STORAGE: Store undiluted antibody at 2-8ºC (until expiry date). For prolonged storage: store aliquots at -20ºC. DILUTION: 1:5 – 1:10 (Based on the Indirect method, with a normal ABC method the dilution can be 5-10x higher, but the optimal dilution should be tested by serial dilution) Dilute immediately before use with PBS or Tris REFERENCE: Berendsen H.H., et al. Detection of small lung cancer metastases in bone marrow aspirates using monoclonal antibodies directed against neuroendocrine differentiation antigen (1988). J. Clin. Pathol, 4, 273-276. 2222MOC-3107.03 WARNING AND CAUTION: This product is intended FOR RESEARCH USE ONLY, " FOR TESTS IN VITRO", not for use in diagnostic or therapeutic procedures involving humans or animals. This product contains sodium azide. To prevent formation of toxic vapors, do not mix with strongly acidic solutions. to prevent formation of potentially explosive metallic azides in metal plumbing, always wash into drain with copious quantities of water.
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