American Laboratory Products Company
PO Box 451 • Windham, NH 03087
Tel.(800)592-5726 • Fax.(603)898-6854
MOC-31 (Lung Cancer Marker) Code: 13-2222MOC-31
SPECIES: Mouse Monoclonal; Hybridoma's: Mouse myeloma X 63-BALB/c
Ig CLASS: IgG1
REAGENT: Culture Supernatant
IMMUNOGEN: Small cell lung carcinoma derived cell line preparation.
CLINICAL APPLICATION: This antibody is reactive with all lung carcinomas and most epithelia.
MOC-31 is unreactive with normal and malignant mesothelia and
therefore especially useful for the detection of carcinoma cells in ascites
or pleural effusions. Immunoblotting: MOC-31 (Cluster 2 antibody) is
directed against a membrane associated protein of 40 kD
APPLICATION: Frozen sections / Cell preparations
Paraffin sections: *
* No pretreatment
* Microwave oven / Autoclave:
* Protease Digestion Trypsin:
POSITIVE CONTROL: Brain / adrenal gland
CONTENTS: 1.0 ml
STORAGE: Store undiluted antibody at 2-8ºC (until expiry date).
For prolonged storage: store aliquots at -20ºC.
DILUTION: 1:5 – 1:10 (Based on the Indirect method, with a normal ABC
method the dilution can be 5-10x higher, but the optimal dilution
should be tested by serial dilution)
Dilute immediately before use with PBS or Tris
REFERENCE: Berendsen H.H., et al. Detection of small lung cancer metastases in
bone marrow aspirates using monoclonal antibodies directed against
neuroendocrine differentiation antigen (1988). J. Clin. Pathol, 4, 273-276.
WARNING AND CAUTION:
This product is intended FOR RESEARCH USE ONLY, " FOR TESTS IN VITRO",
not for use in diagnostic or therapeutic procedures involving humans or animals.
This product contains sodium azide. To prevent formation of toxic vapors, do not mix with strongly acidic
solutions. to prevent formation of potentially explosive metallic azides in metal plumbing, always wash into
drain with copious quantities of water.