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APPENDIXB-MDTsresponsestotrialslistactionplans-vers2-6.09.11

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APPENDIXB-MDTsresponsestotrialslistactionplans-vers2-6.09.11 Powered By Docstoc
					                                 Greater Manchester & Cheshire Cancer Research Network
                                Multi-Disciplinary Team response to NSSG agreed Trials List
                                                    Measures Ref: 11-2C-127

MDT Location: Royal Bolton Hospital                                            MDT Name: Local Lung

List of studies and MDT response:

                                                                                           MDT Comments
                                                                                           Please provide a comment for every trial, for example:
                                                                                           to indicate whether studies are feasible for any sites,
                                                                      Patients recruited   if there are problems with recruitment the plans to
                                                                      in                   remedy issues or studies recruiting well and no action
                                                  Local Status         2010-11(UKCRN       required….
Trial Name                      National Status   (Please Specify)    data)
CONVERT                         Open               Open at Christie   N/A                                  Radiotherapy study
Does smoking after a
diagnosis of lung cancer
make a difference?              Open              N/A                 N/A                                            feasible
Donating lung tissue for
medical
 research                       Open              N/A                 N/A
ET Trial                        Open              Open at Christie    N/A                  Chemotherapy study
FRAGMATIC                       Open              Open at Christie    N/A                  Not open to other sites
IDEAL-CRT                       Open              N/A                 N/A                  To discuss
Living Well with Lung Cancer    Open              Open                7                    Open at Bolton
Lung ART                        In Set-up         N/A                 N/A                  Not open to other sites
LungStar                        Open              N/A                 N/A                  Not open to other sites
MALCS (Mesothelioma and
 Lung Cancer Study)             Open              Open                0                    Open at Bolton
MEDLUNG                         Open              N/A                 N/A                  ? a possibility to open at Bolton. To discuss
Modafinil for Fatigue in Lung
Cancer                          Open              Open at Christie    N/A                  Not open to other sites
NCRN019 - INDUSTRY
 STUDY                          Open              N/A                 N/A                  Not open to other sites
NCRN032 - INDUSTRY
STUDY                           Open              N/A                 N/A                  Not open to other sites
NCRN073                         Open              Open at Christie    N/A                  To discuss
NCRN095 (FORTIS-M)              Open              Open at Christie    N/A                  To discuss
                                                                                                             MDT response to NSSG agreed trials list
                                                                                                                                       Version 1
NCRN147                        Open                   Open at Christie    N/A                  Not open to other sites
QUARTZ                         Open                   N/A                 N/A                  To discuss
ReSoLuCENT                     Open                   Open at Christie    N/A                  Do not have refrigerated centrifuge to open here
REST - Chest Irradiation in
Extensive Disease Small Cell
Lung Cancer                    In Set-up              N/A                 N/A                  Not open to other sites
Supportive Care Intervention
for Lung Cancer Patients and
Caregivers                     Closed                 N/A                 N/A                  Closed
SWAMP trial                    Open                   N/A                 N/A                  To discuss
TACTIC                         Closed                 Open at Christie    N/A                  closed
The SYMPTOM Study              Open                   N/A                 N/A                  To discuss
Time 1                         Open                   N/A                 N/A                  To discuss
Time 3                         Open                   N/A                 N/A                  To discuss
03.05.2011

Recruitment Performance in 2010-11:

In 2010-11: A total of 7 Lung cancer/pre-malignant patients were recruited into all NCRN trials at Royal Bolton Hospital and 0 patients
into NCRN Lung RCTs.

Research Team Comment

2010/2011 was a particularly challenging year for the Research Team, due to a lack of a senior research nurse in post for almost 6 months.
A new Lead Oncology Research Nurse was recruited in February 2011, bringing a wealth of experience which was reflected in positive
changes in practice and increased recruitment in the short space of time before the end of the year. This resulted in the Research Team
meeting their accrual target for 2010/2011. Unfortunately, the team is predicted to undergo a further period of instability due to staff
turnover and it is of paramount importance that a high calibre candidate is recruited to enable the team to build on this year’s success.
Until such time, we will be unable to increase the research portfolio due to safety considerations. We will continue to screen MDT lists to
identify eligible patients for studies that are open and actively recruiting.

MDT Plans:
All lung cancer patients undergoing active treatment are treated at the Christie Hospital, no oncology treatment service exists at Bolton for
this cohort of patients currently. Dr Bayman, clinical oncologist from the Christie attends Bolton weekly & undertakes clinic every Thursday
& is an active member of our sector MDT. On assessing patients for treatment he considers any appropriate trials & discusses these with
them. He will then see them in his research clinic or refer them to the specific consultant leading the appropriate trial eg. Dr Blackhall.
Written information on most of the current trials is kept at Bolton & given to the patient in preparation for their next appointment.


                                                                                                                 MDT response to NSSG agreed trials list
                                                                                                                                           Version 1
I understand that the research team in Bolton is to undergo a period of instability due to staff turnover, so increasing their research portfolio
currently is not possible. Once the team has stabilised future links can be established with the possibility of identifying more patients that
that may be eligible for future trials.


It is important that recruitment to lung studies is reviewed at Bolton. Lung is not a disease group that is adequately covered by the research
team. A meeting is required with the lung team once oncology research is fully staffed to look at areas where we can open studies and
improve recruitment. We also need to explore shared care with Christie hospital due to the lack of chemo and radiotherapy services here at
Bolton.


On behalf of Dr I Webster
Clinical Lead for Lung Cancer
Royal Bolton Hospital




GMCCRN Clinical Lead Comments:
It is encouraging to see the recruitment to the living well with Lung cancer trial has continued and increased. Once the second
research nurse is in post at the MDT could consider opening the Fragmatic trial. To demonstrate the full research activity of the MDT
a mechanism of recording referral for consideration into NCRN trials to The Christie needs to be considered.




Discussed at the Lung CSG meeting on:20/7/2011

Agreed by:

____________________               Date: __20/7/2011_____                     ____________________                Date: __20/7/2011_

Dr Philip Barber                                                             Professor Nigel Bundred
Lung CSG Chair                                                               Greater Manchester and Cheshire Cancer Research
                                                                             Network, Clinical Lead for Research

                                                                                                                  MDT response to NSSG agreed trials list
                                                                                                                                            Version 1
                                 Greater Manchester & Cheshire Cancer Research Network
                                Multi-Disciplinary Team response to NSSG agreed Trials List
                                                  Measures Ref: ____________________

MDT Location: CMFT                                                                             MDT Name: Lung

List of studies and MDT response:

                                                                                               MDT Comments
                                                                                               Please provide a comment for every trial, for example:
                                                                                               to indicate whether studies are feasible for any sites,
                                                                          Patients recruited   if there are problems with recruitment the plans to
                                                                          in                   remedy issues or studies recruiting well and no action
                                                      Local Status         2010-11(UKCRN       required….
Trial Name                      National Status       (Please Specify)    data)
CONVERT                         Open                   Open at Christie   N/A                                Not aware of this study
Does smoking after a
diagnosis of lung cancer
make a difference?              Open                  N/A                 N/A                                Not aware of this study
Donating lung tissue for
medical
 research                       Open                  N/A                 N/A                  Not applicable
ET Trial                        Open                  Open at Christie    N/A                  Not applicable
FRAGMATIC                       Open                  Open at Christie    N/A                  Not recruiting
IDEAL-CRT                       Open                  N/A                 N/A                  Not applicable
Living Well with Lung Cancer    Open                  Open                4                    Recruited in 2009 / 2010
Lung ART                        In Set-up             N/A                 N/A                  Not applicable
LungStar                        Open                  N/A                 N/A                  Not applicable
MALCS (Mesothelioma and
 Lung Cancer Study)             Open                  Open                0                    Not applicable
MEDLUNG                         Open                  N/A                 N/A                  Not applicable
Modafinil for Fatigue in Lung
Cancer                          Open                  Open at Christie    N/A                  Not applicable
NCRN019 - INDUSTRY
 STUDY                          Open                  N/A                 N/A                  Not applicable
NCRN032 - INDUSTRY
STUDY                           Open                  N/A                 N/A                  Not applicable
NCRN073                         Open                  Open at Christie    N/A                  Not applicable
NCRN095 (FORTIS-M)              Open                  Open at Christie    N/A                  Not applicable
                                                                                                                 MDT response to NSSG agreed trials list
                                                                                                                                           Version 1
NCRN147                        Open                   Open at Christie    N/A                   Not applicable
QUARTZ                         Open                   N/A                 N/A                   Not applicable
ReSoLuCENT                     Open                   Open at Christie    N/A                   Not applicable
REST - Chest Irradiation in
Extensive Disease Small Cell
Lung Cancer                    In Set-up              N/A                 N/A                   Not applicable
Supportive Care Intervention
for Lung Cancer Patients and
Caregivers                     Closed                 N/A                 N/A                   Not aware of this study
SWAMP trial                    Open                   N/A                 N/A                   Not applicable
TACTIC                         Closed                 Open at Christie    N/A                   Not applicable
The SYMPTOM Study              Open                   N/A                 N/A                   Not applicable
Time 1                         Open                   N/A                 N/A                   Not applicable
Time 3                         Open                   N/A                 N/A                   Open for recruitment
03.05.2011


Recruitment Performance in 2010-11:



In 2010-11: A total of 4 Lung cancer/pre-malignant patients were recruited into all NCRN trials at CMFT and 0 patients into NCRN Lung
RCTs.




MDT Plans:
Nearly all studies are treatment studies and only accessible at the Christie. Many of our patients go into these studies, but there is no
foolproof and systematic mechanism that alerts us about which patients have been recruited to which trials.

We are always happy to consider studies relevant to diagnostics, staging and palliation which are the main parts of the lung cancer
pathway to which we contribute.




                                                                                                                 MDT response to NSSG agreed trials list
                                                                                                                                           Version 1
GMCCRN Clinical Lead Comments:

As stated in 2009/10 CMFT Lung MDTs report the ability to recruit to the Lung portfolio is limited at the trust but it is pleasing to see the
local recruitment to the Living well with lung cancer study has been maintained in 2010/11. To demonstrate the full research activity of the
MDT a mechanism of recording referral for consideration into NCRN trials to The Christie needs to be considered.



Discussed at the Lung CSG meeting on: 20/7/2011

Agreed by:

____________________              Date: __20/7/2011____________                                        ___ Date: _20/7/2011__________

Dr Philip Barber                                                           Professor Nigel Bundred
Lung CSG Chair                                                             Greater Manchester and Cheshire Cancer Research
                                                                           Network, Clinical Lead for Research




                                                                                                                MDT response to NSSG agreed trials list
                                                                                                                                          Version 1

				
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